guaifenesin 40 MG/ML / hydrocodone bitartrate 0.5 MG/ML / pseudoephedrine hydrochloride 6 MG/ML Oral Solution [Hycofenix]

RxCUI: 1651564
RxNorm name: guaifenesin 40 MG/ML / hydrocodone bitartrate 0.5 MG/ML / pseudoephedrine hydrochloride 6 MG/ML Oral Solution [Hycofenix]
Term type: SBD
Status: Active
Updated: 2026-10-15 15:47:19

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 072015
Active start: 072015
Multiple ingredient: YES
Branded: YES

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
guaifenesin	40 MG / 1 ML	guaifenesin	guaifenesin
hydrocodone bitartrate	0.5 MG / 1 ML	hydrocodone	hydrocodone bitartrate
pseudoephedrine hydrochloride	6 MG / 1 ML	pseudoephedrine	pseudoephedrine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Solution	316968

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
guaifenesin	5032
hydrocodone	5489
pseudoephedrine	8896

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
RXNAV_STR	Hycofenix (HYDROcodone bitartrate 2.5 MG / guaiFENesin 200 MG / pseudoephedrine HCl 30 MG) per 5 ML Oral Solution	1	NAMES
RxNorm Name	guaifenesin 40 MG/ML / hydrocodone bitartrate 0.5 MG/ML / pseudoephedrine hydrochloride 6 MG/ML Oral Solution [Hycofenix]	1	NAMES
RxNorm Synonym	Hycofenix (hydrocodone bitartrate 2.5 MG / guaifenesin 200 MG / pseudoephedrine HCl 30 MG) per 5 ML Oral Solution	1	NAMES
TTY	SBD	1	ATTRIBUTES
RxCUI	1651564	1	CODES
MMSL_CODE	BD30401	1	CODES

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 3 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
00178329104	rxnav_historical
00178329116	rxnav_historical
24470091504	rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 0 matching rows.

No records found.

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	R05CA	Expectorants	ATC1-4		guaifenesin
ATC	R05DA	Opium alkaloids and derivatives	ATC1-4		hydrocodone
ATC	R01BA	Sympathomimetics	ATC1-4		pseudoephedrine
FDASPL	N0000175552	alpha-Adrenergic Agonist	EPC	has_epc	pseudoephedrine
FDASPL	N0000193956	Expectorant	EPC	has_epc	guaifenesin
FDASPL	N0000175690	Opioid Agonist	EPC	has_epc	hydrocodone
FDASPL	N0000000174	Opioid Agonists	MOA	has_moa	hydrocodone
MEDRT	D006140	Guaifenesin	CHEM	has_ingredient	guaifenesin
MEDRT	D006853	Hydrocodone	CHEM	has_ingredient	hydrocodone
MEDRT	D006853	Hydrocodone	CHEM	has_ingredient	hydrocodone bitartrate
MEDRT	D054199	Pseudoephedrine	CHEM	has_ingredient	pseudoephedrine hydrochloride
MEDRT	D054199	Pseudoephedrine	CHEM	has_ingredient	pseudoephedrine
MEDRT	D001249	Asthma	DISEASE	may_treat	pseudoephedrine hydrochloride
MEDRT	D001249	Asthma	DISEASE	ci_with	hydrocodone bitartrate
MEDRT	D001249	Asthma	DISEASE	ci_with	hydrocodone
MEDRT	D001249	Asthma	DISEASE	may_treat	pseudoephedrine
MEDRT	D001991	Bronchitis	DISEASE	may_treat	guaifenesin
MEDRT	D003139	Common Cold	DISEASE	may_treat	pseudoephedrine
MEDRT	D003139	Common Cold	DISEASE	may_treat	pseudoephedrine hydrochloride
MEDRT	D003139	Common Cold	DISEASE	may_treat	guaifenesin
MEDRT	D003371	Cough	DISEASE	may_treat	guaifenesin
MEDRT	D003371	Cough	DISEASE	may_treat	hydrocodone
MEDRT	D003371	Cough	DISEASE	may_treat	hydrocodone bitartrate
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	pseudoephedrine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	guaifenesin
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	hydrocodone bitartrate
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	hydrocodone
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	pseudoephedrine hydrochloride
MEDRT	D007415	Intestinal Obstruction	DISEASE	ci_with	hydrocodone bitartrate
MEDRT	D007415	Intestinal Obstruction	DISEASE	ci_with	hydrocodone
MEDRT	D007827	Laryngitis	DISEASE	may_treat	guaifenesin
MEDRT	D008173	Lung Diseases, Obstructive	DISEASE	may_treat	hydrocodone bitartrate
MEDRT	D008173	Lung Diseases, Obstructive	DISEASE	may_treat	hydrocodone
MEDRT	D010612	Pharyngitis	DISEASE	may_treat	guaifenesin
MEDRT	D010149	Postoperative Pain	DISEASE	may_treat	hydrocodone
MEDRT	D010149	Postoperative Pain	DISEASE	may_treat	hydrocodone bitartrate
MEDRT	D012131	Respiratory Insufficiency	DISEASE	ci_with	hydrocodone
MEDRT	D012131	Respiratory Insufficiency	DISEASE	ci_with	hydrocodone bitartrate
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	guaifenesin
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	pseudoephedrine
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	pseudoephedrine hydrochloride
MEDRT	D012852	Sinusitis	DISEASE	may_treat	guaifenesin
MEDRT	D012852	Sinusitis	DISEASE	may_treat	pseudoephedrine
MEDRT	D012852	Sinusitis	DISEASE	may_treat	pseudoephedrine hydrochloride
MEDRT	D014917	Whooping Cough	DISEASE	may_treat	guaifenesin
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	pseudoephedrine hydrochloride
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	pseudoephedrine
MEDRT	N0000000245	Adrenergic beta-Agonists	MOA	has_moa	pseudoephedrine hydrochloride
MEDRT	N0000000245	Adrenergic beta-Agonists	MOA	has_moa	pseudoephedrine
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	pseudoephedrine hydrochloride
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	pseudoephedrine
MEDRT	N0000191866	Opioid mu-Receptor Agonists	MOA	has_moa	hydrocodone
MEDRT	N0000191866	Opioid mu-Receptor Agonists	MOA	has_moa	hydrocodone bitartrate
MEDRT	N0000175439	Analgesia	PE	has_pe	hydrocodone
MEDRT	N0000175439	Analgesia	PE	has_pe	hydrocodone bitartrate
MEDRT	N0000008322	Bronchodilation	PE	has_pe	pseudoephedrine hydrochloride
MEDRT	N0000008322	Bronchodilation	PE	has_pe	pseudoephedrine
MEDRT	N0000008501	Decreased Central Nervous System Organized Electrical Activity	PE	ci_pe	hydrocodone
MEDRT	N0000008501	Decreased Central Nervous System Organized Electrical Activity	PE	ci_pe	hydrocodone bitartrate
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	hydrocodone bitartrate
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	hydrocodone
MEDRT	N0000008768	Decreased Organized Electrical Activity	PE	has_pe	hydrocodone bitartrate
MEDRT	N0000008768	Decreased Organized Electrical Activity	PE	has_pe	hydrocodone
MEDRT	N0000008867	Decreased Respiratory Secretion Viscosity	PE	has_pe	guaifenesin
MEDRT	N0000009560	Increased Respiratory Secretions	PE	has_pe	guaifenesin
MEDRT	N0000009908	Vasoconstriction	PE	has_pe	pseudoephedrine
MEDRT	N0000009908	Vasoconstriction	PE	has_pe	pseudoephedrine hydrochloride

Group, Type, Concept table
Group	Type	Concept	Source
BN	BN	Hycofenix	rxnav_allrelated
DF	DF	Oral Solution	rxnav_allrelated
DFG	DFG	Oral Liquid Product	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
IN	IN	guaifenesin	rxnav_allrelated
IN	IN	hydrocodone	rxnav_allrelated
IN	IN	pseudoephedrine	rxnav_allrelated
MIN	MIN	guaifenesin / hydrocodone / pseudoephedrine	rxnav_allrelated
PIN	PIN	hydrocodone bitartrate	rxnav_allrelated
PIN	PIN	pseudoephedrine hydrochloride	rxnav_allrelated
SBD	SBD	guaifenesin 40 MG/ML / hydrocodone bitartrate 0.5 MG/ML / pseudoephedrine hydrochloride 6 MG/ML Oral Solution [Hycofenix]	rxnav_allrelated
SBDC	SBDC	guaifenesin 40 MG/ML / hydrocodone bitartrate 0.5 MG/ML / pseudoephedrine hydrochloride 6 MG/ML [Hycofenix]	rxnav_allrelated
SBDF	SBDF	guaifenesin / hydrocodone / pseudoephedrine Oral Solution [Hycofenix]	rxnav_allrelated
SBDFP	SBDFP	guaifenesin / hydrocodone bitartrate / pseudoephedrine hydrochloride Oral Solution [Hycofenix]	rxnav_allrelated
SBDG	SBDG	Hycofenix Oral Liquid Product	rxnav_allrelated
SBDG	SBDG	Hycofenix Oral Product	rxnav_allrelated
SCD	SCD	guaifenesin 40 MG/ML / hydrocodone bitartrate 0.5 MG/ML / pseudoephedrine hydrochloride 6 MG/ML Oral Solution	rxnav_allrelated
SCDC	SCDC	guaifenesin 40 MG/ML	rxnav_allrelated
SCDC	SCDC	hydrocodone bitartrate 0.5 MG/ML	rxnav_allrelated
SCDC	SCDC	pseudoephedrine hydrochloride 6 MG/ML	rxnav_allrelated
SCDF	SCDF	guaifenesin / hydrocodone / pseudoephedrine Oral Solution	rxnav_allrelated
SCDFP	SCDFP	guaifenesin / hydrocodone bitartrate / pseudoephedrine hydrochloride Oral Solution	rxnav_allrelated
SCDG	SCDG	guaifenesin / hydrocodone / pseudoephedrine Oral Liquid Product	rxnav_allrelated
SCDG	SCDG	guaifenesin / hydrocodone / pseudoephedrine Oral Product	rxnav_allrelated
SCDGP	SCDGP	guaifenesin / hydrocodone bitartrate / pseudoephedrine hydrochloride Oral Liquid Product	rxnav_allrelated
SCDGP	SCDGP	guaifenesin / hydrocodone bitartrate / pseudoephedrine hydrochloride Oral Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	SCHEDULE	2
NAMES	Prescribable Synonym	Hycofenix 2.5 MG / 200 MG / 30 MG in 5 mL Oral Solution
NAMES	Tallman Synonym	guaiFENesin 40 MG/ML / HYDROcodone bitartrate 0.5 MG/ML / pseudoephedrine hydrochloride 6 MG/ML Oral Solution [Hycofenix]
NAMES	Tallman Synonym	Hycofenix (HYDROcodone bitartrate 2.5 MG / guaiFENesin 200 MG / pseudoephedrine HCl 30 MG) per 5 ML Oral Solution
SOURCES	Source	Multum MediSource Lexicon