1.8 ML bupivacaine hydrochloride 5 MG/ML / epinephrine 0.005 MG/ML Cartridge

RxCUI: 1670365
RxNorm name: 1.8 ML bupivacaine hydrochloride 5 MG/ML / epinephrine 0.005 MG/ML Cartridge
Display name: BUPivacaine/EPINEPHrine (Injectable)
Full name: 1.8 ML bupivacaine hydrochloride 5 MG/ML / epinephrine 0.005 MG/ML Cartridge
Term type: SCD
Status: Active
Strength: 5-0.005 mg/ml
Dose form: Cartridge 1.8 ml
Route: Injectable
Updated: 2026-10-27 17:48:25

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 112015
Active start: 112015
Multiple ingredient: YES
Branded: NO

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
bupivacaine hydrochloride	5 MG / 1 ML	bupivacaine	bupivacaine hydrochloride
epinephrine bitartrate	5 MCG / 1 ML	epinephrine	epinephrine

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Cartridge	1649572

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
bupivacaine	1815
epinephrine	3992

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
PRESCRIBABLE	Y	1	ATTRIBUTES
RXNAV_STR	1.8 ML BUPivacaine hydrochloride 5 MG/ML / EPINEPHrine 0.005 MG/ML Cartridge	1	NAMES
RxNorm Name	1.8 ML bupivacaine hydrochloride 5 MG/ML / epinephrine 0.005 MG/ML Cartridge	1	NAMES
RxNorm Synonym	bupivacaine HCl 0.5 % / epinephrine 1:200,000 per 1.8 ML Dental Cartridge	1	NAMES
TTY	SCD	1	ATTRIBUTES
RxCUI	1670365	1	CODES

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 1 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
00409760001	rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Marcaine	BUPIVACAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE	Septodont, Inc.	3e196aa4-0b01-44db-9267-98a995b54743	2025-10-10	Warnings, Adverse reactions	Exact identifier rxcui: 1670365
Vivacaine	BUPIVACAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE	Septodont, Inc.	b4c60d8e-e350-45b2-9d6b-5815eeb6c994	2024-02-16	Warnings, Adverse reactions	Exact identifier rxcui: 1670365

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 2 matching rows.

Set ID, RxNorm mappings, Terms table
Set ID	RxNorm mappings	Terms	SPL version	Label	Effective
b4c60d8e-e350-45b2-9d6b-5815eeb6c994	BUPivacaine HCl 0.5 % / EPINEPHrine 1:200,000 in 1.8 ML Dental Cartridge [PSN] · 1.8 ML bupivacaine hydrochloride 5 MG/ML / epinephrine 0.005 MG/ML Cartridge [SCD] · bupivacaine HCl 0.5 % / epinephrine 1:200,000 per 1.8 ML Dental Cartridge [SY]	3	11	Vivacaine® Bupivacaine HCl 0.5% (5 mg/mL) and Epinephrine 1:200,000 Injection (as bitartrate) (Bupivacaine Hydrochloride and Epinephrine Injection, USP)	20240216
3e196aa4-0b01-44db-9267-98a995b54743	BUPivacaine HCl 0.5 % / EPINEPHrine 1:200,000 in 1.8 ML Dental Cartridge [PSN] · 1.8 ML bupivacaine hydrochloride 5 MG/ML / epinephrine 0.005 MG/ML Cartridge [SCD] · bupivacaine HCl 0.5 % / epinephrine 1:200,000 per 1.8 ML Dental Cartridge [SY]	3	5	Marcaine® 0.5% (5 mg/mL) with epinephrine 1:200,000 injection (as bitartrate) (bupivacaine hydrochloride and epinephrine injection, USP)	20251010

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
8292cff2-4985-4c9a-bcff-1615a008d1e3		National Council for Prescription Drug Programs	20120724

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	C01CA	Adrenergic and dopaminergic agents	ATC1-4		epinephrine
ATC	R03AA	Alpha- and beta-adrenoreceptor agonists	ATC1-4		epinephrine
ATC	N01BB	Amides	ATC1-4		bupivacaine
ATC	B02BC	Local hemostatics	ATC1-4		epinephrine
ATC	A01AD	Other agents for local oral treatment	ATC1-4		epinephrine
ATC	S01EA	Sympathomimetics in glaucoma therapy	ATC1-4		epinephrine
ATC	R01AA	Sympathomimetics, plain	ATC1-4		epinephrine
FDASPL	D000577	Amides	CHEM	has_chemical_structure	bupivacaine
FDASPL	D002395	Catecholamines	CHEM	has_chemical_structure	epinephrine
FDASPL	N0000175552	alpha-Adrenergic Agonist	EPC	has_epc	epinephrine
FDASPL	N0000175682	Amide Local Anesthetic	EPC	has_epc	bupivacaine
FDASPL	N0000175555	beta-Adrenergic Agonist	EPC	has_epc	epinephrine
FDASPL	N0000175570	Catecholamine	EPC	has_epc	epinephrine
FDASPL	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	epinephrine
FDASPL	N0000000245	Adrenergic beta-Agonists	MOA	has_moa	epinephrine
FDASPL	N0000175976	Local Anesthesia	PE	has_pe	bupivacaine
MEDRT	D002045	Bupivacaine	CHEM	has_ingredient	bupivacaine
MEDRT	D002045	Bupivacaine	CHEM	has_ingredient	bupivacaine hydrochloride
MEDRT	D004837	Epinephrine	CHEM	has_ingredient	epinephrine
MEDRT	D000402	Airway Obstruction	DISEASE	may_treat	epinephrine
MEDRT	D000707	Anaphylaxis	DISEASE	may_treat	epinephrine
MEDRT	D001145	Arrhythmias, Cardiac	DISEASE	ci_with	epinephrine
MEDRT	D001919	Bradycardia	DISEASE	may_treat	epinephrine
MEDRT	D001986	Bronchial Spasm	DISEASE	may_treat	epinephrine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	bupivacaine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	epinephrine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	bupivacaine hydrochloride
MEDRT	D015812	Glaucoma, Angle-Closure	DISEASE	ci_with	epinephrine
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	epinephrine
MEDRT	D006323	Heart Arrest	DISEASE	may_treat	epinephrine
MEDRT	D006327	Heart Block	DISEASE	may_treat	epinephrine
MEDRT	D007022	Hypotension	DISEASE	may_treat	epinephrine
MEDRT	D010146	Pain	DISEASE	may_prevent	bupivacaine hydrochloride
MEDRT	D010146	Pain	DISEASE	may_prevent	bupivacaine
MEDRT	D010149	Postoperative Pain	DISEASE	may_treat	bupivacaine hydrochloride
MEDRT	D010149	Postoperative Pain	DISEASE	may_treat	bupivacaine
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	epinephrine
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	may_treat	epinephrine
MEDRT	D014693	Ventricular Fibrillation	DISEASE	may_treat	epinephrine
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	epinephrine
MEDRT	N0000009921	Adrenergic beta1-Agonists	MOA	has_moa	epinephrine
MEDRT	N0000009922	Adrenergic beta2-Agonists	MOA	has_moa	epinephrine
MEDRT	N0000000108	Prostaglandin Receptor Antagonists	MOA	has_moa	bupivacaine hydrochloride
MEDRT	N0000000108	Prostaglandin Receptor Antagonists	MOA	has_moa	bupivacaine
MEDRT	N0000000180	Sodium Channel Interactions	MOA	has_moa	bupivacaine hydrochloride
MEDRT	N0000000180	Sodium Channel Interactions	MOA	has_moa	bupivacaine
MEDRT	N0000008298	Arterial Vasoconstriction	PE	has_pe	epinephrine
MEDRT	N0000008322	Bronchodilation	PE	has_pe	epinephrine
MEDRT	N0000009944	Decreased Intraocular Aqueous Secretion	PE	has_pe	epinephrine
MEDRT	N0000008768	Decreased Organized Electrical Activity	PE	has_pe	bupivacaine hydrochloride
MEDRT	N0000008768	Decreased Organized Electrical Activity	PE	has_pe	bupivacaine
MEDRT	N0000009014	Decreased Uterine Smooth Muscle Contraction or Tone	PE	has_pe	epinephrine
MEDRT	N0000009070	Hemostasis Alteration	PE	has_pe	epinephrine
MEDRT	N0000178478	Increased Blood Pressure	PE	has_pe	epinephrine
MEDRT	N0000175976	Local Anesthesia	PE	has_pe	bupivacaine hydrochloride
MEDRT	N0000175976	Local Anesthesia	PE	has_pe	bupivacaine
MEDRT	N0000009808	Positive Chronotropy	PE	has_pe	epinephrine
MEDRT	N0000009809	Positive Inotropy	PE	has_pe	epinephrine
MEDRT	N0000009820	Pupillary Dilation	PE	has_pe	epinephrine

Group, Type, Concept table
Group	Type	Concept	Source
BN	BN	Marcaine with Epinephrine	rxnav_allrelated
BN	BN	Vivacaine	rxnav_allrelated
DF	DF	Cartridge	rxnav_allrelated
DFG	DFG	Injectable Product	rxnav_allrelated
IN	IN	bupivacaine	rxnav_allrelated
IN	IN	epinephrine	rxnav_allrelated
MIN	MIN	bupivacaine / epinephrine	rxnav_allrelated
PIN	PIN	bupivacaine hydrochloride	rxnav_allrelated
SBD	SBD	1.8 ML bupivacaine hydrochloride 5 MG/ML / epinephrine 0.005 MG/ML Cartridge [Marcaine with Epinephrine]	rxnav_allrelated
SBD	SBD	1.8 ML bupivacaine hydrochloride 5 MG/ML / epinephrine 0.005 MG/ML Cartridge [Vivacaine]	rxnav_allrelated
SBDC	SBDC	bupivacaine hydrochloride 5 MG/ML / epinephrine 0.005 MG/ML [Marcaine with Epinephrine]	rxnav_allrelated
SBDC	SBDC	bupivacaine hydrochloride 5 MG/ML / epinephrine 0.005 MG/ML [Vivacaine]	rxnav_allrelated
SBDF	SBDF	bupivacaine / epinephrine Cartridge [Marcaine with Epinephrine]	rxnav_allrelated
SBDF	SBDF	bupivacaine / epinephrine Cartridge [Vivacaine]	rxnav_allrelated
SBDFP	SBDFP	bupivacaine hydrochloride / epinephrine Cartridge [Marcaine with Epinephrine]	rxnav_allrelated
SBDFP	SBDFP	bupivacaine hydrochloride / epinephrine Cartridge [Vivacaine]	rxnav_allrelated
SBDG	SBDG	Marcaine with Epinephrine Injectable Product	rxnav_allrelated
SBDG	SBDG	Vivacaine Injectable Product	rxnav_allrelated
SCD	SCD	1.8 ML bupivacaine hydrochloride 5 MG/ML / epinephrine 0.005 MG/ML Cartridge	rxnav_allrelated
SCDC	SCDC	bupivacaine hydrochloride 5 MG/ML	rxnav_allrelated
SCDC	SCDC	epinephrine 0.005 MG/ML	rxnav_allrelated
SCDF	SCDF	bupivacaine / epinephrine Cartridge	rxnav_allrelated
SCDFP	SCDFP	bupivacaine hydrochloride / epinephrine Cartridge	rxnav_allrelated
SCDG	SCDG	bupivacaine / epinephrine Injectable Product	rxnav_allrelated
SCDGP	SCDGP	bupivacaine hydrochloride / epinephrine Injectable Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	5 MG/ML / 0.005 MG/ML
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	QUANTITY	1.8 ML
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
ATTRIBUTES	SCHEDULE	0
CODES	VUID	4004275
NAMES	Prescribable Synonym	BUPivacaine HCl 0.5 % / EPINEPHrine 1:200,000 in 1.8 ML Dental Cartridge
NAMES	Tallman Synonym	1.8 ML BUPivacaine hydrochloride 5 MG/ML / EPINEPHrine 0.005 MG/ML Cartridge
NAMES	Tallman Synonym	BUPivacaine HCl 0.5 % / EPINEPHrine 1:200,000 per 1.8 ML Dental Cartridge
SOURCES	Source	National Drug Data File Plus Source Vocabulary
SOURCES	Source	Veterans Health Administration National Drug File