acetaminophen 25 MG/ML / chlorpheniramine maleate 0.4 MG/ML / dextromethorphan hydrobromide 1.33 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution

RxCUI: 1743369
RxNorm name: acetaminophen 25 MG/ML / chlorpheniramine maleate 0.4 MG/ML / dextromethorphan hydrobromide 1.33 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution
Term type: SCD
Status: Active
Updated: 2026-10-22 07:01:08

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 042016
Active start: 042016
Multiple ingredient: YES
Branded: NO

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
acetaminophen	25 MG / 1 ML	acetaminophen	acetaminophen
chlorpheniramine maleate	0.4 MG / 1 ML	chlorpheniramine	chlorpheniramine maleate
dextromethorphan hydrobromide	1.33 MG / 1 ML	dextromethorphan	dextromethorphan hydrobromide
guaifenesin	20 MG / 1 ML	guaifenesin	guaifenesin
phenylephrine hydrochloride	0.5 MG / 1 ML	phenylephrine	phenylephrine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Oral Solution	316968

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
acetaminophen	161
chlorpheniramine	2400
dextromethorphan	3289
guaifenesin	5032
phenylephrine	8163

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
RXNAV_STR	acetaminophen 25 MG/ML / chlorpheniramine maleate 0.4 MG/ML / dextromethorphan hydrobromide 1.33 MG/ML / guaiFENesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution	1	NAMES
RxNorm Name	acetaminophen 25 MG/ML / chlorpheniramine maleate 0.4 MG/ML / dextromethorphan hydrobromide 1.33 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution	1	NAMES
RxNorm Synonym	2 linked values acetaminophen 250 MG / chlorpheniramine maleate 4 MG / dextromethorphan HBr 13.33 MG / guaifenesin 200 MG / phenylephrine HCl 5 MG per 10 ML Oral Solution APAP 25 MG/ML / Chlorpheniramine Maleate 0.4 MG/ML / Dextromethorphan Hydrobromide 1.33 MG/ML / Guaifenesin 20 MG/ML / Phenylephrine Hydrochloride 0.5 MG/ML Oral Solution	2	NAMES
TTY	SCD	1	ATTRIBUTES
SPL_SET_ID	d0426469-9dd1-4bd1-b81e-69d33187daa2	1	CODES
RxCUI	1743369	1	CODES

FDA NDC Products And Packages#

Package NDC, Product NDC, Name table
Package NDC	Product NDC	Name	Labeler	Application
65131-116-87	65131-116	BRONCOCHEM ACETAMINOPHEN-CHLORPHENIRAMINE MALEATE-DEXTROMETHORPHAN HBr-GUAIFENESIN-PHENYLEPHRINE HCl	LABORATORIO MAGNACHEM INTERNATIONAL SRL	part343

Drugs@FDA Applications#

Application, NDC, Name table
Application	NDC	Name	Marketing category	Labeler
part343	65131-116	BRONCOCHEM ACETAMINOPHEN-CHLORPHENIRAMINE MALEATE-DEXTROMETHORPHAN HBr-GUAIFENESIN-PHENYLEPHRINE HCl	OTC MONOGRAPH NOT FINAL	LABORATORIO MAGNACHEM INTERNATIONAL SRL

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 1 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
65131011687	rxnav_ndcs	yes

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
BRONCOCHEM EXPECTORANT II	ACETAMINOPHEN-CHLORPHENIRAMINE MALEATE-DEXTROMETHORPHAN HBR-GUAIFENESIN-PHENYLEPHRINE HCL	LABORATORIO MAGNACHEM INTERNATIONAL SRL	d0426469-9dd1-4bd1-b81e-69d33187daa2	2016-12-19	Warnings	Exact identifier ndc (package): 65131-116-87 ndc (product): 65131-116 ndc11 (package): 65131011687 rxcui: 1743369

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 1 matching rows.

Set ID, RxNorm mappings, Terms table
Set ID	RxNorm mappings	Terms	SPL version	Label	Effective
d0426469-9dd1-4bd1-b81e-69d33187daa2	acetaminophen 250 MG / chlorpheniramine maleate 4 MG / dextromethorphan HBr 13.33 MG / guaiFENesin 200 MG / phenylephrine HCl 5 MG in 10 mL Oral Solution [PSN] · acetaminophen 25 MG/ML / chlorpheniramine maleate 0.4 MG/ML / dextromethorphan hydrobromide 1.33 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution [SCD] · acetaminophen 250 MG / chlorpheniramine maleate 4 MG / dextromethorphan HBr 13.33 MG / guaifenesin 200 MG / phenylephrine HCl 5 MG per 10 ML Oral Solution [SY] · APAP 25 MG/ML / Chlorpheniramine Maleate 0.4 MG/ML / Dextromethorphan Hydrobromide 1.33 MG/ML / Guaifenesin 20 MG/ML / Phenylephrine Hydrochloride 0.5 MG/ML Oral Solution [SY]	4	2	BRONCOCHEM EXPECTORANT II	20161219

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
d0426469-9dd1-4bd1-b81e-69d33187daa2	BRONCOCHEM EXPECTORANT II	LABORATORIO MAGNACHEM INTERNATIONAL SRL	20161219

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	C01CA	Adrenergic and dopaminergic agents	ATC1-4		phenylephrine
ATC	N02BE	Anilides	ATC1-4		acetaminophen
ATC	R05CA	Expectorants	ATC1-4		guaifenesin
ATC	R05DA	Opium alkaloids and derivatives	ATC1-4		dextromethorphan
ATC	C05AX	Other agents for treatment of hemorrhoids and anal fissures for topical use	ATC1-4		phenylephrine
ATC	R06AB	Substituted alkylamines	ATC1-4		chlorpheniramine
ATC	R01BA	Sympathomimetics	ATC1-4		phenylephrine
ATC	S01FB	Sympathomimetics excl. antiglaucoma preparations	ATC1-4		phenylephrine
ATC	S01GA	Sympathomimetics used as decongestants	ATC1-4		phenylephrine
ATC	R01AB	Sympathomimetics, combinations excl. corticosteroids	ATC1-4		phenylephrine
ATC	R01AA	Sympathomimetics, plain	ATC1-4		phenylephrine
FDASPL	N0000186105	alpha-1 Adrenergic Agonist	EPC	has_epc	phenylephrine
FDASPL	N0000193956	Expectorant	EPC	has_epc	guaifenesin
FDASPL	N0000175587	Histamine-1 Receptor Antagonist	EPC	has_epc	chlorpheniramine
FDASPL	N0000182149	Sigma-1 Agonist	EPC	has_epc	dextromethorphan
FDASPL	N0000181821	Uncompetitive N-methyl-D-aspartate Receptor Antagonist	EPC	has_epc	dextromethorphan
FDASPL	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan
FDASPL	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan
MEDRT	D000082	Acetaminophen	CHEM	has_ingredient	acetaminophen
MEDRT	D002744	Chlorpheniramine	CHEM	has_ingredient	chlorpheniramine maleate
MEDRT	D002744	Chlorpheniramine	CHEM	has_ingredient	chlorpheniramine
MEDRT	D003915	Dextromethorphan	CHEM	has_ingredient	dextromethorphan
MEDRT	D003915	Dextromethorphan	CHEM	has_ingredient	dextromethorphan hydrobromide
MEDRT	D006140	Guaifenesin	CHEM	has_ingredient	guaifenesin
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine hydrochloride
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine hydrochloride
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine
MEDRT	D001991	Bronchitis	DISEASE	may_treat	guaifenesin
MEDRT	D003139	Common Cold	DISEASE	may_treat	guaifenesin
MEDRT	D003371	Cough	DISEASE	may_treat	dextromethorphan hydrobromide
MEDRT	D003371	Cough	DISEASE	may_treat	dextromethorphan
MEDRT	D003371	Cough	DISEASE	may_prevent	dextromethorphan
MEDRT	D003371	Cough	DISEASE	may_treat	guaifenesin
MEDRT	D003371	Cough	DISEASE	may_prevent	dextromethorphan hydrobromide
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	dextromethorphan
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	acetaminophen
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	chlorpheniramine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	dextromethorphan hydrobromide
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	guaifenesin
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D004380	Duodenal Obstruction	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D004380	Duodenal Obstruction	DISEASE	ci_with	chlorpheniramine
MEDRT	D005334	Fever	DISEASE	may_prevent	acetaminophen
MEDRT	D005334	Fever	DISEASE	may_treat	acetaminophen
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D015812	Glaucoma, Angle-Closure	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D015812	Glaucoma, Angle-Closure	DISEASE	ci_with	chlorpheniramine
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine
MEDRT	D005955	Glucosephosphate Dehydrogenase Deficiency	DISEASE	ci_with	acetaminophen
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D007231	Infant, Newborn	DISEASE	ci_with	chlorpheniramine
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D007234	Infant, Premature	DISEASE	ci_with	chlorpheniramine
MEDRT	D007827	Laryngitis	DISEASE	may_treat	guaifenesin
MEDRT	D008107	Liver Diseases	DISEASE	ci_with	acetaminophen
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine hydrochloride
MEDRT	D010146	Pain	DISEASE	may_treat	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_prevent	acetaminophen
MEDRT	D010437	Peptic Ulcer	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D010437	Peptic Ulcer	DISEASE	ci_with	chlorpheniramine
MEDRT	D010612	Pharyngitis	DISEASE	may_treat	guaifenesin
MEDRT	D011470	Prostatic Hyperplasia	DISEASE	ci_with	chlorpheniramine
MEDRT	D011470	Prostatic Hyperplasia	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	chlorpheniramine
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	chlorpheniramine maleate
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	guaifenesin
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012852	Sinusitis	DISEASE	may_treat	guaifenesin
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	chlorpheniramine
MEDRT	D013224	Status Asthmaticus	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D001748	Urinary Bladder Neck Obstruction	DISEASE	ci_with	chlorpheniramine maleate
MEDRT	D001748	Urinary Bladder Neck Obstruction	DISEASE	ci_with	chlorpheniramine
MEDRT	D014581	Urticaria	DISEASE	may_treat	chlorpheniramine
MEDRT	D014581	Urticaria	DISEASE	may_treat	chlorpheniramine maleate
MEDRT	D014917	Whooping Cough	DISEASE	may_treat	guaifenesin
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine hydrochloride
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	chlorpheniramine maleate
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	chlorpheniramine
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	dextromethorphan
MEDRT	N0000000184	Monoamine Oxidase Inhibitors	MOA	ci_moa	dextromethorphan hydrobromide
MEDRT	N0000000108	Prostaglandin Receptor Antagonists	MOA	has_moa	acetaminophen
MEDRT	N0000000109	Serotonin Uptake Inhibitors	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000000109	Serotonin Uptake Inhibitors	MOA	has_moa	dextromethorphan
MEDRT	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000182147	Sigma-1 Receptor Agonists	MOA	has_moa	dextromethorphan
MEDRT	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan hydrobromide
MEDRT	N0000181819	Uncompetitive NMDA Receptor Antagonists	MOA	has_moa	dextromethorphan
MEDRT	N0000175724	Central Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine hydrochloride
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	chlorpheniramine
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	chlorpheniramine maleate
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	dextromethorphan hydrobromide
MEDRT	N0000008701	Decreased Medullary Respiratory Drive	PE	has_pe	dextromethorphan
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine hydrochloride
MEDRT	N0000008836	Decreased Prostaglandin Production	PE	has_pe	acetaminophen
MEDRT	N0000008867	Decreased Respiratory Secretion Viscosity	PE	has_pe	guaifenesin

Group, Type, Concept table
Group	Type	Concept	Source
DF	DF	Oral Solution	rxnav_allrelated
DFG	DFG	Oral Liquid Product	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
IN	IN	acetaminophen	rxnav_allrelated
IN	IN	chlorpheniramine	rxnav_allrelated
IN	IN	dextromethorphan	rxnav_allrelated
IN	IN	guaifenesin	rxnav_allrelated
IN	IN	phenylephrine	rxnav_allrelated
MIN	MIN	acetaminophen / chlorpheniramine / dextromethorphan / guaifenesin / phenylephrine	rxnav_allrelated
PIN	PIN	chlorpheniramine maleate	rxnav_allrelated
PIN	PIN	dextromethorphan hydrobromide	rxnav_allrelated
PIN	PIN	phenylephrine hydrochloride	rxnav_allrelated
SCD	SCD	acetaminophen 25 MG/ML / chlorpheniramine maleate 0.4 MG/ML / dextromethorphan hydrobromide 1.33 MG/ML / guaifenesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution	rxnav_allrelated
SCDC	SCDC	acetaminophen 25 MG/ML	rxnav_allrelated
SCDC	SCDC	chlorpheniramine maleate 0.4 MG/ML	rxnav_allrelated
SCDC	SCDC	dextromethorphan hydrobromide 1.33 MG/ML	rxnav_allrelated
SCDC	SCDC	guaifenesin 20 MG/ML	rxnav_allrelated
SCDC	SCDC	phenylephrine hydrochloride 0.5 MG/ML	rxnav_allrelated
SCDF	SCDF	acetaminophen / chlorpheniramine / dextromethorphan / guaifenesin / phenylephrine Oral Solution	rxnav_allrelated
SCDFP	SCDFP	acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Solution	rxnav_allrelated
SCDG	SCDG	acetaminophen / chlorpheniramine / dextromethorphan / guaifenesin / phenylephrine Oral Liquid Product	rxnav_allrelated
SCDG	SCDG	acetaminophen / chlorpheniramine / dextromethorphan / guaifenesin / phenylephrine Oral Product	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Liquid Product	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / chlorpheniramine maleate / dextromethorphan hydrobromide / guaifenesin / phenylephrine hydrochloride Oral Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	25 MG/ML / 0.4 MG/ML / 1.33 MG/ML / 20 MG/ML / 0.5 MG/ML
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
NAMES	Prescribable Synonym	acetaminophen 250 MG / chlorpheniramine maleate 4 MG / dextromethorphan HBr 13.33 MG / guaiFENesin 200 MG / phenylephrine HCl 5 MG in 10 mL Oral Solution
NAMES	Tallman Synonym	acetaminophen 25 MG/ML / chlorpheniramine maleate 0.4 MG/ML / dextromethorphan hydrobromide 1.33 MG/ML / guaiFENesin 20 MG/ML / phenylephrine hydrochloride 0.5 MG/ML Oral Solution
NAMES	Tallman Synonym	acetaminophen 250 MG / chlorpheniramine maleate 4 MG / dextromethorphan HBr 13.33 MG / guaiFENesin 200 MG / phenylephrine HCl 5 MG per 10 ML Oral Solution
NAMES	Tallman Synonym	APAP 25 MG/ML / Chlorpheniramine Maleate 0.4 MG/ML / Dextromethorphan Hydrobromide 1.33 MG/ML / guaiFENesin 20 MG/ML / Phenylephrine Hydrochloride 0.5 MG/ML Oral Solution
SOURCES	Source	Metathesaurus FDA Structured Product Labels