acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution

RxCUI: 1796460
RxNorm name: acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution
Display name: Acetaminophen/Pheniramine/Phenylephrine (Oral Solution Powder)
Full name: acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution
Term type: SCD
Status: Active
Strength: 325-20-10 mg
Dose form: Pwdr
Route: Oral Solution Powder
Updated: 2026-10-24 12:29:26

RxNorm Status History#

Status: Active
Source: RXNORM
Current: YES
Release start: 072016
Active start: 072016
Multiple ingredient: YES
Branded: NO

Ingredients And Strength#

Ingredient, Strength, Base table
Ingredient	Strength	Base	Basis of strength
acetaminophen	325 MG / 1 EACH	acetaminophen	acetaminophen
pheniramine maleate	20 MG / 1 EACH	pheniramine	pheniramine maleate
phenylephrine hydrochloride	10 MG / 1 EACH	phenylephrine	phenylephrine hydrochloride

Dose Form Concepts#

Dose form, RxCUI table
Dose form	RxCUI
Powder for Oral Solution	1540455

Derived Ingredient Concepts#

Ingredient, RxCUI table
Ingredient	RxCUI
acetaminophen	161
pheniramine	8132
phenylephrine	8163

Source Vocabulary Codes#

Code type, Values, Count table
Code type	Values	Count	Category
PRESCRIBABLE	Y	1	ATTRIBUTES
RXNAV_STR	acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution	1	NAMES
RxNorm Name	acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution	1	NAMES
RxNorm Synonym	3 linked values acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Granule for Oral Solution acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Packet for Oral Solution APAP 325 MG / Pheniramine Maleate 20 MG / Phenylephrine Hydrochloride 10 MG Powder for Oral Solution	3	NAMES
TTY	SCD	1	ATTRIBUTES
SPL_SET_ID	2 linked values 7fd78fc6-1f80-4866-bb8b-6dbf8af80482 e49a93a8-158a-4184-b4bc-cac3031ad8b6	2	CODES
RxCUI	1796460	1	CODES
MMSL_CODE	BD16296	1	CODES

RxNav Current And Historical NDCs#

RxNav current and historical NDC rows page 1 of 1 · 12 matching rows.

NDC11, Source, Active table
NDC11	Source	Active
00363060106	rxnav_ndcs	yes
00043046716	rxnav_historical
00043631906	rxnav_historical
00067092401	rxnav_historical
00067631906	rxnav_historical
00067671606	rxnav_historical
00067813510	rxnav_historical_indirect
36800080206	rxnav_historical
59779041006	rxnav_historical
63868076506	rxnav_historical
64525070106	rxnav_historical
73147317306	rxnav_historical

UNII Substances#

UNII substance links page 1 of 1 · 0 matching rows.

No records found.

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed RxNorm Mappings#

unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 7 matching rows.

Set ID, RxNorm mappings, Terms table
Set ID	RxNorm mappings	Terms	SPL version	Label	Effective
e49a93a8-158a-4184-b4bc-cac3031ad8b6	acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine HCl 10 MG Powder for Oral Solution [PSN] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution [SCD] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Granule for Oral Solution [SY] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Packet for Oral Solution [SY] · APAP 325 MG / Pheniramine Maleate 20 MG / Phenylephrine Hydrochloride 10 MG Powder for Oral Solution [SY]	5	7	Drug Facts	20240424
fc99da1f-5ce7-4bc4-b6b5-09020cbdac64	acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine HCl 10 MG Powder for Oral Solution [PSN] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution [SCD] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Granule for Oral Solution [SY] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Packet for Oral Solution [SY] · APAP 325 MG / Pheniramine Maleate 20 MG / Phenylephrine Hydrochloride 10 MG Powder for Oral Solution [SY]	5	7	Walgreens Wal-Flu Cold and Sore Throat Lemon Flavor	20160331
7fd78fc6-1f80-4866-bb8b-6dbf8af80482	acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine HCl 10 MG Powder for Oral Solution [PSN] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution [SCD] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Granule for Oral Solution [SY] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Packet for Oral Solution [SY] · APAP 325 MG / Pheniramine Maleate 20 MG / Phenylephrine Hydrochloride 10 MG Powder for Oral Solution [SY]	5	4	Drug Facts	20240502
7047e4b8-d111-4540-89e0-5f29dc17a03d	acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine HCl 10 MG Powder for Oral Solution [PSN] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution [SCD] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Granule for Oral Solution [SY] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Packet for Oral Solution [SY] · APAP 325 MG / Pheniramine Maleate 20 MG / Phenylephrine Hydrochloride 10 MG Powder for Oral Solution [SY]	5	2	Quality Choice Cold and Sore Throat Lemon Flavor	20160107
4c9a91d9-c8fa-4845-ab06-e3f760acc798	acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine HCl 10 MG Powder for Oral Solution [PSN] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution [SCD] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Granule for Oral Solution [SY] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Packet for Oral Solution [SY] · APAP 325 MG / Pheniramine Maleate 20 MG / Phenylephrine Hydrochloride 10 MG Powder for Oral Solution [SY]	5	2	TopCare Cold and Sore Throat Lemon Flavor	20130926
ef12626d-dc9e-4e07-9e97-6edf0ea82f9c	acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine HCl 10 MG Powder for Oral Solution [PSN] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution [SCD] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Granule for Oral Solution [SY] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Packet for Oral Solution [SY] · APAP 325 MG / Pheniramine Maleate 20 MG / Phenylephrine Hydrochloride 10 MG Powder for Oral Solution [SY]	5	1	Topcare Cold and Sore Throat Lemon Flavor	20140520
49ada090-e70e-476f-89ce-9647c064e1e6	acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine HCl 10 MG Powder for Oral Solution [PSN] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution [SCD] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Granule for Oral Solution [SY] · acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Packet for Oral Solution [SY] · APAP 325 MG / Pheniramine Maleate 20 MG / Phenylephrine Hydrochloride 10 MG Powder for Oral Solution [SY]	5	1	CVS Pharmacy Cold and Sore Throat Lemon Flavor	20130401

Recently Linked DailyMed Labels#

Set ID, Title, Manufacturer table
Set ID	Title	Manufacturer	Effective
7fd78fc6-1f80-4866-bb8b-6dbf8af80482	Drug Facts	Haleon US Holdings LLC	20240502
e49a93a8-158a-4184-b4bc-cac3031ad8b6	Drug Facts	Haleon US Holdings LLC	20240424
6c2d9335-34ac-460f-89c7-3a90cfc1301c	Cold & Sore Throat	Cellchem Pharmaceuticals Inc \| Laboratoires Confab Inc	20221128
fc99da1f-5ce7-4bc4-b6b5-09020cbdac64	Walgreens Wal-Flu Cold and Sore Throat Lemon Flavor	Walgreen Co.	20160331
7047e4b8-d111-4540-89e0-5f29dc17a03d	Quality Choice Cold and Sore Throat Lemon Flavor	Chain Drug Marketing Association	20160107
ef12626d-dc9e-4e07-9e97-6edf0ea82f9c	Topcare Cold and Sore Throat Lemon Flavor	TOPCARE (Topco Associates LLC)	20140520
4c9a91d9-c8fa-4845-ab06-e3f760acc798	TopCare Cold and Sore Throat Lemon Flavor	Quality Home Products	20130926
49ada090-e70e-476f-89ce-9647c064e1e6	CVS Pharmacy Cold and Sore Throat Lemon Flavor	CVS Pharmacy	20130401

Drug Classes#

Source, Class ID, Class table
Source	Class ID	Class	Type	Relationship	Drug concept
ATC	C01CA	Adrenergic and dopaminergic agents	ATC1-4		phenylephrine
ATC	N02BE	Anilides	ATC1-4		acetaminophen
ATC	D04AA	Antihistamines for topical use	ATC1-4		pheniramine
ATC	C05AX	Other agents for treatment of hemorrhoids and anal fissures for topical use	ATC1-4		phenylephrine
ATC	R06AB	Substituted alkylamines	ATC1-4		pheniramine
ATC	R01BA	Sympathomimetics	ATC1-4		phenylephrine
ATC	S01FB	Sympathomimetics excl. antiglaucoma preparations	ATC1-4		phenylephrine
ATC	S01GA	Sympathomimetics used as decongestants	ATC1-4		phenylephrine
ATC	R01AB	Sympathomimetics, combinations excl. corticosteroids	ATC1-4		phenylephrine
ATC	R01AA	Sympathomimetics, plain	ATC1-4		phenylephrine
FDASPL	N0000186105	alpha-1 Adrenergic Agonist	EPC	has_epc	phenylephrine
MEDRT	D000082	Acetaminophen	CHEM	has_ingredient	acetaminophen
MEDRT	D010632	Pheniramine	CHEM	has_ingredient	pheniramine
MEDRT	D010632	Pheniramine	CHEM	has_ingredient	pheniramine maleate
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine
MEDRT	D010656	Phenylephrine	CHEM	has_ingredient	phenylephrine hydrochloride
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine
MEDRT	D013447	Sulfites	CHEM	ci_chemclass	phenylephrine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	pheniramine maleate
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	phenylephrine
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	acetaminophen
MEDRT	D004342	Drug Hypersensitivity	DISEASE	ci_with	pheniramine
MEDRT	D005334	Fever	DISEASE	may_treat	acetaminophen
MEDRT	D005334	Fever	DISEASE	may_prevent	acetaminophen
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D005401	Fissure in Ano	DISEASE	may_treat	phenylephrine
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D005902	Glaucoma, Open-Angle	DISEASE	may_treat	phenylephrine
MEDRT	D005955	Glucosephosphate Dehydrogenase Deficiency	DISEASE	ci_with	acetaminophen
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D006484	Hemorrhoids	DISEASE	may_treat	phenylephrine
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D006973	Hypertension	DISEASE	ci_with	phenylephrine
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D007022	Hypotension	DISEASE	may_treat	phenylephrine
MEDRT	D008107	Liver Diseases	DISEASE	ci_with	acetaminophen
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine hydrochloride
MEDRT	D015878	Mydriasis	DISEASE	induces	phenylephrine
MEDRT	D010146	Pain	DISEASE	may_prevent	acetaminophen
MEDRT	D010146	Pain	DISEASE	may_treat	acetaminophen
MEDRT	D011537	Pruritus	DISEASE	may_treat	pheniramine maleate
MEDRT	D011537	Pruritus	DISEASE	may_treat	pheniramine
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D011538	Pruritus Ani	DISEASE	may_treat	phenylephrine
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_prevent	pheniramine
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	pheniramine
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_prevent	pheniramine maleate
MEDRT	D012221	Rhinitis, Allergic, Perennial	DISEASE	may_treat	pheniramine maleate
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012223	Rhinitis, Vasomotor	DISEASE	may_treat	phenylephrine
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D012772	Shock, Septic	DISEASE	may_treat	phenylephrine
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine
MEDRT	D013617	Tachycardia, Supraventricular	DISEASE	may_treat	phenylephrine hydrochloride
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine
MEDRT	D017180	Tachycardia, Ventricular	DISEASE	ci_with	phenylephrine hydrochloride
MEDRT	D014581	Urticaria	DISEASE	may_prevent	pheniramine maleate
MEDRT	D014581	Urticaria	DISEASE	may_treat	pheniramine maleate
MEDRT	D014581	Urticaria	DISEASE	may_treat	pheniramine
MEDRT	D014581	Urticaria	DISEASE	may_prevent	pheniramine
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine
MEDRT	N0000000209	Adrenergic alpha-Agonists	MOA	has_moa	phenylephrine hydrochloride
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	pheniramine maleate
MEDRT	N0000000190	Histamine H1 Receptor Antagonists	MOA	has_moa	pheniramine
MEDRT	N0000000108	Prostaglandin Receptor Antagonists	MOA	has_moa	acetaminophen
MEDRT	N0000175724	Central Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine
MEDRT	N0000008371	Conjunctival Arterial Vasoconstriction	PE	has_pe	phenylephrine hydrochloride
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	pheniramine
MEDRT	N0000008657	Decreased Histamine Activity	PE	has_pe	pheniramine maleate
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine
MEDRT	N0000008896	Decreased Nasal and Sinus Secretions	PE	has_pe	phenylephrine hydrochloride
MEDRT	N0000008836	Decreased Prostaglandin Production	PE	has_pe	acetaminophen
MEDRT	N0000009072	Hypothalamic Endocrine Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000175725	Peripheral Nervous System Activity Alteration	PE	has_pe	acetaminophen
MEDRT	N0000000026	Hepatic Metabolism	PK	has_pk	acetaminophen
MEDRT	N0000000042	Renal Excretion	PK	has_pk	acetaminophen

Group, Type, Concept table
Group	Type	Concept	Source
DF	DF	Powder for Oral Solution	rxnav_allrelated
DFG	DFG	Oral Powder Product	rxnav_allrelated
DFG	DFG	Oral Product	rxnav_allrelated
IN	IN	acetaminophen	rxnav_allrelated
IN	IN	pheniramine	rxnav_allrelated
IN	IN	phenylephrine	rxnav_allrelated
MIN	MIN	acetaminophen / pheniramine / phenylephrine	rxnav_allrelated
PIN	PIN	pheniramine maleate	rxnav_allrelated
PIN	PIN	phenylephrine hydrochloride	rxnav_allrelated
SCD	SCD	acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine hydrochloride 10 MG Powder for Oral Solution	rxnav_allrelated
SCDC	SCDC	acetaminophen 325 MG	rxnav_allrelated
SCDC	SCDC	pheniramine maleate 20 MG	rxnav_allrelated
SCDC	SCDC	phenylephrine hydrochloride 10 MG	rxnav_allrelated
SCDF	SCDF	acetaminophen / pheniramine / phenylephrine Powder for Oral Solution	rxnav_allrelated
SCDFP	SCDFP	acetaminophen / pheniramine maleate / phenylephrine hydrochloride Powder for Oral Solution	rxnav_allrelated
SCDG	SCDG	acetaminophen / pheniramine / phenylephrine Oral Powder Product	rxnav_allrelated
SCDG	SCDG	acetaminophen / pheniramine / phenylephrine Oral Product	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / pheniramine maleate / phenylephrine hydrochloride Oral Powder Product	rxnav_allrelated
SCDGP	SCDGP	acetaminophen / pheniramine maleate / phenylephrine hydrochloride Oral Product	rxnav_allrelated

Properties#

Category, Property, Value table
Category	Property	Value
ATTRIBUTES	AVAILABLE_STRENGTH	325 MG / 20 MG / 10 MG
ATTRIBUTES	GENERAL_CARDINALITY	MULTI
ATTRIBUTES	HUMAN_DRUG	US
ATTRIBUTES	RXNAV_HUMAN_DRUG	US
NAMES	Prescribable Synonym	acetaminophen 325 MG / pheniramine maleate 20 MG / phenylephrine HCl 10 MG Powder for Oral Solution
SOURCES	Source	Metathesaurus FDA Structured Product Labels
SOURCES	Source	National Drug Data File Plus Source Vocabulary