Home RxNorm 2049283 acetaminophen 33.3 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML / pseudoephedrine hydrochloride 2 MG/ML Oral Solution Drug identity information. FDA.report links public drug records from RxNav, DailyMed, FDA NDC, Drugs@FDA, and related public sources where available. This page is informational only and is not medical, prescribing, or regulatory advice.
RxCUI 2049283
RxNorm name acetaminophen 33.3 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML / pseudoephedrine hydrochloride 2 MG/ML Oral Solution
Display name Acetaminophen/Chlorpheniramine/Dextromethorphan/Pseudoephedrine (Oral Liquid)
Full name acetaminophen 33.3 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML / pseudoephedrine hydrochloride 2 MG/ML Oral Solution
Term type SCD
Status Active
Strength 1,000-4.0-30-60 mg/30ml
Dose form Sol
Route Oral Liquid
Updated 2026-11-08 10:05:27 RxNorm Status History#
Status Active
Source RXNORM
Current YES
Release start 082018
Active start 082018
Multiple ingredient YES
Branded NO Ingredients And Strength# Derived Ingredient Concepts# FDA NDC Products And Packages# Package NDC, Product NDC, Name table Package NDC Product NDC Name Labeler Application 0067-0114-01 0067-0114 Theraflu-D Flu Relief Max Strength plus Nasal Decongestant Acetaminophen, Chlorpheniramine maleate, Dextromethorphan HBr, Pseudoephedrine HCl Haleon US Holdings LLC M012
Drugs@FDA Applications# Application, NDC, Name table Application NDC Name Marketing category Labeler M012 0067-0114 Theraflu-D Flu Relief Max Strength plus Nasal Decongestant Acetaminophen, Chlorpheniramine maleate, Dextromethorphan HBr, Pseudoephedrine HCl OTC MONOGRAPH DRUG Haleon US Holdings LLC
RxNav Current And Historical NDCs# RxNav current and historical NDC rows page 1 of 1 · 4 matching rows.
NDC11, Source, Active table NDC11 Source Active 00067011401 rxnav_ndcs yes 19810020361 rxnav_historical_indirect 19810030116 rxnav_historical_indirect 19810056405 rxnav_historical_indirect
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No records found.
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DailyMed RxNorm Mappings# unique DailyMed labels mapped to this RxNorm concept page 1 of 1 · 1 matching rows.
Set ID, RxNorm mappings, Terms table Set ID RxNorm mappings Terms SPL version Label Effective 09e20842-2b75-43b9-ae5f-3515b35e655b acetaminophen 1000 MG / chlorpheniramine maleate 4 MG / dextromethorphan HBr 30 MG / pseudoephedrine HCl 60 MG in 30 mL Oral Solution [PSN] · acetaminophen 33.3 MG/ML / chlorpheniramine maleate 0.133 MG/ML / dextromethorphan hydrobromide 1 MG/ML / pseudoephedrine hydrochloride 2 MG/ML Oral Solution [SCD] · acetaminophen 1000 MG / chlorpheniramine maleate 4 MG / dextromethorphan HBr 30 MG / pseudoephedrine HCl 60 MG per 30 ML Oral Solution [SY] · APAP 33.3 MG/ML / Chlorpheniramine Maleate 0.133 MG/ML / Dextromethorphan Hydrobromide 1 MG/ML / Pseudoephedrine Hydrochloride 2 MG/ML Oral Solution [SY] 4 1 Drug Facts 20240503
Recently Linked DailyMed Labels# Drug Classes# Source, Class ID, Class table Source Class ID Class Type Relationship Drug concept ATC N02BE Anilides ATC1-4 acetaminophen ATC R05DA Opium alkaloids and derivatives ATC1-4 dextromethorphan ATC R06AB Substituted alkylamines ATC1-4 chlorpheniramine ATC R01BA Sympathomimetics ATC1-4 pseudoephedrine FDASPL N0000175552 alpha-Adrenergic Agonist EPC has_epc pseudoephedrine FDASPL N0000175587 Histamine-1 Receptor Antagonist EPC has_epc chlorpheniramine FDASPL N0000182149 Sigma-1 Agonist EPC has_epc dextromethorphan FDASPL N0000181821 Uncompetitive N-methyl-D-aspartate Receptor Antagonist EPC has_epc dextromethorphan FDASPL N0000182147 Sigma-1 Receptor Agonists MOA has_moa dextromethorphan FDASPL N0000181819 Uncompetitive NMDA Receptor Antagonists MOA has_moa dextromethorphan MEDRT D000082 Acetaminophen CHEM has_ingredient acetaminophen MEDRT D002744 Chlorpheniramine CHEM has_ingredient chlorpheniramine MEDRT D002744 Chlorpheniramine CHEM has_ingredient chlorpheniramine maleate MEDRT D003915 Dextromethorphan CHEM has_ingredient dextromethorphan hydrobromide MEDRT D003915 Dextromethorphan CHEM has_ingredient dextromethorphan MEDRT D054199 Pseudoephedrine CHEM has_ingredient pseudoephedrine MEDRT D054199 Pseudoephedrine CHEM has_ingredient pseudoephedrine hydrochloride MEDRT D001249 Asthma DISEASE may_treat pseudoephedrine hydrochloride MEDRT D001249 Asthma DISEASE may_treat pseudoephedrine MEDRT D003139 Common Cold DISEASE may_treat pseudoephedrine MEDRT D003139 Common Cold DISEASE may_treat pseudoephedrine hydrochloride MEDRT D003371 Cough DISEASE may_prevent dextromethorphan hydrobromide MEDRT D003371 Cough DISEASE may_treat dextromethorphan hydrobromide MEDRT D003371 Cough DISEASE may_prevent dextromethorphan MEDRT D003371 Cough DISEASE may_treat dextromethorphan MEDRT D004342 Drug Hypersensitivity DISEASE ci_with dextromethorphan MEDRT D004342 Drug Hypersensitivity DISEASE ci_with chlorpheniramine MEDRT D004342 Drug Hypersensitivity DISEASE ci_with acetaminophen MEDRT D004342 Drug Hypersensitivity DISEASE ci_with dextromethorphan hydrobromide MEDRT D004342 Drug Hypersensitivity DISEASE ci_with pseudoephedrine MEDRT D004342 Drug Hypersensitivity DISEASE ci_with chlorpheniramine maleate MEDRT D004342 Drug Hypersensitivity DISEASE ci_with pseudoephedrine hydrochloride MEDRT D004380 Duodenal Obstruction DISEASE ci_with chlorpheniramine maleate MEDRT D004380 Duodenal Obstruction DISEASE ci_with chlorpheniramine MEDRT D005334 Fever DISEASE may_prevent acetaminophen MEDRT D005334 Fever DISEASE may_treat acetaminophen MEDRT D015812 Glaucoma, Angle-Closure DISEASE ci_with chlorpheniramine maleate MEDRT D015812 Glaucoma, Angle-Closure DISEASE ci_with chlorpheniramine MEDRT D005955 Glucosephosphate Dehydrogenase Deficiency DISEASE ci_with acetaminophen MEDRT D007231 Infant, Newborn DISEASE ci_with chlorpheniramine maleate MEDRT D007231 Infant, Newborn DISEASE ci_with chlorpheniramine MEDRT D007234 Infant, Premature DISEASE ci_with chlorpheniramine maleate MEDRT D007234 Infant, Premature DISEASE ci_with chlorpheniramine MEDRT D008107 Liver Diseases DISEASE ci_with acetaminophen MEDRT D010146 Pain DISEASE may_treat acetaminophen MEDRT D010146 Pain DISEASE may_prevent acetaminophen MEDRT D010437 Peptic Ulcer DISEASE ci_with chlorpheniramine MEDRT D010437 Peptic Ulcer DISEASE ci_with chlorpheniramine maleate MEDRT D011470 Prostatic Hyperplasia DISEASE ci_with chlorpheniramine MEDRT D011470 Prostatic Hyperplasia DISEASE ci_with chlorpheniramine maleate MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat chlorpheniramine maleate MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat chlorpheniramine MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat pseudoephedrine MEDRT D012221 Rhinitis, Allergic, Perennial DISEASE may_treat pseudoephedrine hydrochloride MEDRT D012852 Sinusitis DISEASE may_treat pseudoephedrine hydrochloride MEDRT D012852 Sinusitis DISEASE may_treat pseudoephedrine MEDRT D013224 Status Asthmaticus DISEASE ci_with chlorpheniramine maleate MEDRT D013224 Status Asthmaticus DISEASE ci_with chlorpheniramine MEDRT D001748 Urinary Bladder Neck Obstruction DISEASE ci_with chlorpheniramine MEDRT D001748 Urinary Bladder Neck Obstruction DISEASE ci_with chlorpheniramine maleate MEDRT D014581 Urticaria DISEASE may_treat chlorpheniramine MEDRT D014581 Urticaria DISEASE may_treat chlorpheniramine maleate MEDRT N0000000209 Adrenergic alpha-Agonists MOA has_moa pseudoephedrine MEDRT N0000000209 Adrenergic alpha-Agonists MOA has_moa pseudoephedrine hydrochloride MEDRT N0000000245 Adrenergic beta-Agonists MOA has_moa pseudoephedrine hydrochloride MEDRT N0000000245 Adrenergic beta-Agonists MOA has_moa pseudoephedrine MEDRT N0000000190 Histamine H1 Receptor Antagonists MOA has_moa chlorpheniramine maleate MEDRT N0000000190 Histamine H1 Receptor Antagonists MOA has_moa chlorpheniramine MEDRT N0000000184 Monoamine Oxidase Inhibitors MOA ci_moa dextromethorphan MEDRT N0000000184 Monoamine Oxidase Inhibitors MOA ci_moa dextromethorphan hydrobromide MEDRT N0000000184 Monoamine Oxidase Inhibitors MOA ci_moa pseudoephedrine MEDRT N0000000184 Monoamine Oxidase Inhibitors MOA ci_moa pseudoephedrine hydrochloride MEDRT N0000000108 Prostaglandin Receptor Antagonists MOA has_moa acetaminophen MEDRT N0000000109 Serotonin Uptake Inhibitors MOA has_moa dextromethorphan MEDRT N0000000109 Serotonin Uptake Inhibitors MOA has_moa dextromethorphan hydrobromide MEDRT N0000182147 Sigma-1 Receptor Agonists MOA has_moa dextromethorphan hydrobromide MEDRT N0000182147 Sigma-1 Receptor Agonists MOA has_moa dextromethorphan MEDRT N0000181819 Uncompetitive NMDA Receptor Antagonists MOA has_moa dextromethorphan hydrobromide MEDRT N0000181819 Uncompetitive NMDA Receptor Antagonists MOA has_moa dextromethorphan MEDRT N0000008322 Bronchodilation PE has_pe pseudoephedrine MEDRT N0000008322 Bronchodilation PE has_pe pseudoephedrine hydrochloride MEDRT N0000175724 Central Nervous System Activity Alteration PE has_pe acetaminophen MEDRT N0000008657 Decreased Histamine Activity PE has_pe chlorpheniramine maleate MEDRT N0000008657 Decreased Histamine Activity PE has_pe chlorpheniramine MEDRT N0000008701 Decreased Medullary Respiratory Drive PE has_pe dextromethorphan hydrobromide MEDRT N0000008701 Decreased Medullary Respiratory Drive PE has_pe dextromethorphan MEDRT N0000008836 Decreased Prostaglandin Production PE has_pe acetaminophen MEDRT N0000009072 Hypothalamic Endocrine Activity Alteration PE has_pe acetaminophen MEDRT N0000175725 Peripheral Nervous System Activity Alteration PE has_pe acetaminophen MEDRT N0000009908 Vasoconstriction PE has_pe pseudoephedrine MEDRT N0000009908 Vasoconstriction PE has_pe pseudoephedrine hydrochloride MEDRT N0000000026 Hepatic Metabolism PK has_pk acetaminophen MEDRT N0000000042 Renal Excretion PK has_pk acetaminophen
Properties# Category, Property, Value table Category Property Value ATTRIBUTES ACTIVATED 06/25/2024 ATTRIBUTES AVAILABLE_STRENGTH 33.3 MG/ML / 0.133 MG/ML / 1 MG/ML / 2 MG/ML ATTRIBUTES GENERAL_CARDINALITY MULTI ATTRIBUTES HUMAN_DRUG US ATTRIBUTES RXNAV_HUMAN_DRUG US ATTRIBUTES SCHEDULE 0 NAMES Prescribable Synonym acetaminophen 1000 MG / chlorpheniramine maleate 4 MG / dextromethorphan HBr 30 MG / pseudoephedrine HCl 60 MG in 30 mL Oral Solution SOURCES Source Gold Standard Alchemy SOURCES Source Metathesaurus FDA Structured Product Labels SOURCES Source Micromedex RED BOOK SOURCES Source Multum MediSource Lexicon SOURCES Source National Drug Data File Plus Source Vocabulary