Application 012250

Type
NDA
Sponsor
HOSPIRA

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001CARBOCAINEMEPIVACAINE HYDROCHLORIDEINJECTABLE;INJECTION1%YesYes
002CARBOCAINEMEPIVACAINE HYDROCHLORIDEINJECTABLE;INJECTION2%YesYes
005CARBOCAINEMEPIVACAINE HYDROCHLORIDEINJECTABLE;INJECTION1.5%YesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N012250-001CARBOCAINEMEPIVACAINE HYDROCHLORIDE1% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD, Approved before 1982
N012250-002CARBOCAINEMEPIVACAINE HYDROCHLORIDE2% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD, Approved before 1982
N012250-005CARBOCAINEMEPIVACAINE HYDROCHLORIDE1.5% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD, Approved before 1982

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 126 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N012250-001CARBOCAINE1% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD, Approved before 1982caaa826d4ba7…
2026-08-18 06:07:402026-07N012250-002CARBOCAINE2% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD, Approved before 1982caaa826d4ba7…
2026-08-18 06:07:402026-07N012250-005CARBOCAINE1.5% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD, Approved before 1982caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N012250-001CARBOCAINE1%INJECTABLE / INJECTIONRLD, Approved before 1982011fe1cb6892…
2026-02-19 14:30 UTC2026-02N012250-002CARBOCAINE2%INJECTABLE / INJECTIONRLD, Approved before 1982011fe1cb6892…
2026-02-19 14:30 UTC2026-02N012250-005CARBOCAINE1.5%INJECTABLE / INJECTIONRLD, Approved before 1982011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N012250-001CARBOCAINE1%INJECTABLE / INJECTIONRLD, Approved before 198231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N012250-002CARBOCAINE2%INJECTABLE / INJECTIONRLD, Approved before 198231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N012250-005CARBOCAINE1.5%INJECTABLE / INJECTIONRLD, Approved before 198231067a03dcf5…
2025-08-23 18:47 UTC2025-08N012250-001CARBOCAINE1%INJECTABLE / INJECTIONRLD, Approved before 19826a471c1ec25d…
2025-08-23 18:47 UTC2025-08N012250-002CARBOCAINE2%INJECTABLE / INJECTIONRLD, Approved before 19826a471c1ec25d…
2025-08-23 18:47 UTC2025-08N012250-005CARBOCAINE1.5%INJECTABLE / INJECTIONRLD, Approved before 19826a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N012250-001CARBOCAINE1%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N012250-002CARBOCAINE2%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N012250-005CARBOCAINE1.5%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N012250-001CARBOCAINE1%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N012250-002CARBOCAINE2%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N012250-005CARBOCAINE1.5%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N012250-001CARBOCAINE1%INJECTABLE / INJECTIONAPRLD, RS, Approved before 198203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N012250-002CARBOCAINE2%INJECTABLE / INJECTIONAPRLD, RS, Approved before 198203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N012250-005CARBOCAINE1.5%INJECTABLE / INJECTIONAPRLD, RS, Approved before 198203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N012250-001CARBOCAINE1%INJECTABLE / INJECTIONAPRLD, RS, Approved before 19822680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N012250-002CARBOCAINE2%INJECTABLE / INJECTIONAPRLD, RS, Approved before 19822680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N012250-005CARBOCAINE1.5%INJECTABLE / INJECTIONAPRLD, RS, Approved before 19822680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N012250-001CARBOCAINE1%INJECTABLE / INJECTIONAPRLD, RS, Approved before 19825bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N012250-002CARBOCAINE2%INJECTABLE / INJECTIONAPRLD, RS, Approved before 19825bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N012250-005CARBOCAINE1.5%INJECTABLE / INJECTIONAPRLD, RS, Approved before 19825bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N012250-001CARBOCAINE1%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N012250-002CARBOCAINE2%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N012250-005CARBOCAINE1.5%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N012250-001CARBOCAINE1%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982d06236e962d9…
2024-10-29 15:01 UTC2024-10N012250-002CARBOCAINE2%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982d06236e962d9…
2024-10-29 15:01 UTC2024-10N012250-005CARBOCAINE1.5%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N012250-001CARBOCAINE1%INJECTABLE / INJECTIONAPRLD, RS, Approved before 198279d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N012250-002CARBOCAINE2%INJECTABLE / INJECTIONAPRLD, RS, Approved before 198279d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N012250-005CARBOCAINE1.5%INJECTABLE / INJECTIONAPRLD, RS, Approved before 198279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N012250-001CARBOCAINE1%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N012250-002CARBOCAINE2%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N012250-005CARBOCAINE1.5%INJECTABLE / INJECTIONAPRLD, RS, Approved before 1982301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N012250-001CARBOCAINE1%INJECTABLE / INJECTIONAPRLD, RS, Approved before 19821e350fbaab3a…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 111 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N012250-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N012250-002AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N012250-005AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N012250-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N012250-002AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N012250-005AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N012250-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N012250-002AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N012250-005AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N012250-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N012250-002AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N012250-005AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N012250-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N012250-002AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N012250-005AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N012250-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N012250-002AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N012250-005AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N012250-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10N012250-002AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10N012250-005AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N012250-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N012250-002AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N012250-005AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N012250-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N012250-002AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N012250-005AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N012250-001AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N012250-002AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N012250-005AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N012250-001AP18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N012250-002AP18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N012250-005AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N012250-001AP15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N012250-002AP15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N012250-005AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N012250-001AP15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N012250-002AP15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N012250-005AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N012250-001AP14b0b4de00fa7…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 12 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Scandonest 3% PlainMEPIVACAINE HYDROCHLORIDESeptodont, Inc.af6ff5f6-7221-421b-9b7c-8fcee4a477722025-05-29Warnings, Adverse reactionsName fallback
generic name: MEPIVACAINE HYDROCHLORIDE
MEPIVACAINE HYDROCHLORIDEMEPIVACAINE HYDROCHLORIDESafco Dental Supply Co.c4d45717-86c9-45bf-ba8e-2c255814ab502024-02-21Warnings, Adverse reactionsName fallback
generic name: MEPIVACAINE HYDROCHLORIDE
MepivacaineMEPIVACAINE HYDROCHLORIDENovocol Pharmaceutical of Canada, Inc.f58cb2c7-22a6-4341-8f9a-85c5628af7972024-02-21Warnings, Adverse reactionsName fallback
generic name: MEPIVACAINE HYDROCHLORIDE
MepivacaineMEPIVACAINE HYDROCHLORIDEDarby Dental Supply, LLC5e81dae6-e55b-4d5e-9318-1d9395db052e2024-02-21Warnings, Adverse reactionsName fallback
generic name: MEPIVACAINE HYDROCHLORIDE
Mepivacaine HydrochlorideMEPIVACAINE HYDROCHLORIDEHenry Schein Inc.a3c2cddc-827b-4644-9060-e2fd2188b4592024-02-21Warnings, Adverse reactionsName fallback
generic name: MEPIVACAINE HYDROCHLORIDE
CarbocaineMEPIVACAINE HYDROCHLORIDESeptodont, Inc.1f2f9e40-e437-4124-97b7-df67dbafd1542024-02-21Warnings, Adverse reactionsName fallback
brand name: Carbocaine
generic name: MEPIVACAINE HYDROCHLORIDE
PolocaineMEPIVACAINE HYDROCHLORIDENovocol Pharmaceutical of Canada Inc.eb7e2284-fe8d-46ad-b1d3-92ee2c6222bf2024-02-21Warnings, Adverse reactionsName fallback
generic name: MEPIVACAINE HYDROCHLORIDE
MepivacaineMEPIVACAINE HYDROCHLORIDEBenco Dentalc9a5a849-d010-4637-a66a-c26176401fbd2024-02-21Warnings, Adverse reactionsName fallback
generic name: MEPIVACAINE HYDROCHLORIDE
MepivacaineMEPIVACAINE HYDROCHLORIDENDC, Inc.042010fb-7161-4336-b91f-5a25839ee6442024-02-21Warnings, Adverse reactionsName fallback
generic name: MEPIVACAINE HYDROCHLORIDE
MepivacaineMEPIVACAINE HYDROCHLORIDEPatterson Dental Supply, Inc.e8a3df4b-e918-4813-af3e-3c95f2c542502024-02-21Warnings, Adverse reactionsName fallback
generic name: MEPIVACAINE HYDROCHLORIDE
PolocaineMEPIVACAINE HYDROCHLORIDEDentsply Pharmaceutical25074a6a-7f67-4ad8-86e0-2afe23ec5d042024-02-21Warnings, Adverse reactionsName fallback
generic name: MEPIVACAINE HYDROCHLORIDE
Polocaine-MPFMEPIVACAINE HYDROCHLORIDEFresenius Kabi USA, LLCa27d0815-ae6b-4a21-a8f5-564c01e838142022-10-01Warnings, Adverse reactionsName fallback
generic name: MEPIVACAINE HYDROCHLORIDE

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 26 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
0409-1036CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1036CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1036CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1036CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1036CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1038CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1038CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1038CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1038CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1038CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1038CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1041CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1041CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1041CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1041CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1041CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1067CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1067CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1067CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1067CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-1067CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-2047CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-2047CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-2047CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-2047CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent
0409-2047CarbocaineMepivacaine HydrochlorideHospira, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
77112SUPPL 2023-12-26
77114SUPPL 2023-12-22
56319SUPPL2018-11-06
56258SUPPL2018-11-05
33079SUPPL2010-02-25
314SUPPL2010-02-25
11995SUPPL2005-10-20
10799SUPPL2005-09-30