Application 021248

Type
NDA
Sponsor
CEPHALON

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001TRISENOXARSENIC TRIOXIDEINJECTABLE;INJECTION1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**YesNo
002TRISENOXARSENIC TRIOXIDEINJECTABLE;INJECTION2MG/MLYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021248-001TRISENOXARSENIC TRIOXIDE1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-25
N021248-002TRISENOXARSENIC TRIOXIDE2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-13

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N021248-002AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-13011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-1331067a03dcf5…
2025-08-23 18:47 UTC2025-08N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-136a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-25fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-13fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-25b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-13b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-2503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-1303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-252680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-132680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-255bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-135bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-25d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-13d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-25d06236e962d9…
2024-10-29 15:01 UTC2024-10N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-13d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-2579d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-1379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-25301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-13301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-251e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-131e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-258072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-138072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-255c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-135c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021248-001TRISENOX1MG/MLINJECTABLE / INJECTIONRLD2000-09-255d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-135d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021248-001TRISENOX1MG/MLINJECTABLE / INJECTIONRLD2000-09-254b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-134b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**INJECTABLE / INJECTIONRLD2000-09-2574a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-1374a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**INJECTABLE / INJECTIONRLD2000-09-25bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-13bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021248-001TRISENOX1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**INJECTABLE / INJECTIONRLD2000-09-25782e0a99824c…
2021-12-28 21:50 UTC2021-12N021248-002TRISENOX2MG/MLINJECTABLE / INJECTIONAPRLD, RS2017-10-13782e0a99824c…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N021248-002AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021248-002AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08N021248-002AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021248-002AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021248-002AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021248-002AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021248-002AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021248-002AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021248-002AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021248-002AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021248-002AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021248-002AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021248-002AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021248-002AP18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021248-002AP15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021248-002AP15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021248-002AP14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021248-002AP174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021248-002AP1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021248-002AP1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021248-002AP187673890dc5c…
2021-03-12 10:30 UTC2021-03N021248-002AP15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N021248-002AP18869cabd3fbd…
2020-11-12 02:37 UTC2020-11N021248-002AP1c0c555d07b60…
2019-12-14 00:12 UTC2019-12N021248-002AP13f01610625f2…
2019-09-15 20:21 UTC2019-09N021248-002AP1b00525d2431f…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N021248-002AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N021248-002AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N021248-002AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N021248-002AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N021248-002AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N021248-002AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N021248-002AP13f0d92c62455…
2023-05-13 08:27 UTC2023-05N021248-002AP1053a50430f4f…
2023-01-26 05:58 UTC2023-01N021248-002AP13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N021248-002AP13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N021248-002AP1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N021248-002AP1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N021248-002AP1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N021248-002AP1a50c72e98297…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 78 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021248-001ODE-1672025-01-1231067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021248-002ODE-1672025-01-1231067a03dcf5…
2025-08-23 18:47 UTC2025-08N021248-001ODE-1672025-01-126a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021248-002ODE-1672025-01-126a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021248-001ODE-1672025-01-12fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021248-002ODE-1672025-01-12fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021248-001ODE-1672025-01-12b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021248-002ODE-1672025-01-12b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021248-001ODE-1672025-01-1203ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021248-002ODE-1672025-01-1203ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021248-001ODE-1672025-01-122680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021248-002ODE-1672025-01-122680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021248-001ODE-1672025-01-125bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021248-002ODE-1672025-01-125bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021248-001ODE-1672025-01-12d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021248-002ODE-1672025-01-12d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021248-001ODE-1672025-01-12d06236e962d9…
2024-10-29 15:01 UTC2024-10N021248-002ODE-1672025-01-12d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021248-001ODE-1672025-01-1279d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021248-002ODE-1672025-01-1279d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021248-001ODE-1672025-01-12301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021248-002ODE-1672025-01-12301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021248-001ODE-1672025-01-121e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021248-002ODE-1672025-01-121e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021248-001ODE-1672025-01-128072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021248-002ODE-1672025-01-128072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021248-001ODE-1672025-01-125c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021248-002ODE-1672025-01-125c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021248-001ODE-1672025-01-125d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021248-002ODE-1672025-01-125d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021248-001ODE-1672025-01-124b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021248-002ODE-1672025-01-124b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021248-001ODE-1672025-01-1274a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021248-002ODE-1672025-01-1274a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021248-001ODE-1672025-01-12bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021248-002ODE-1672025-01-12bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021248-001ODE-1672025-01-12782e0a99824c…
2021-12-28 21:50 UTC2021-12N021248-002ODE-1672025-01-12782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021248-001ODE-1672025-01-1287673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N021248-002ODE-1672025-01-1287673890dc5c…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TrisenoxARSENIC TRIOXIDECephalon, LLC101fc347-d0ad-4aee-8b06-9feb187fd7412025-10-28Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021248
application number: NDA021248
ndc (product): 63459-601

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 12 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
63459-600TrisenoxArsenic TrioxideCephalon, Inc.NDACurrent
63459-600TrisenoxArsenic TrioxideCephalon, Inc.NDACurrent
63459-600TrisenoxArsenic TrioxideCephalon, Inc.NDACurrent
63459-601TrisenoxArsenic TrioxideCephalon, LLCNDACurrent
63459-601TrisenoxArsenic TrioxideCephalon, Inc.NDACurrent
63459-601TrisenoxArsenic TrioxideCephalon, Inc.NDACurrent
63459-601TrisenoxArsenic TrioxideCephalon, Inc.NDACurrent
63459-601TrisenoxArsenic TrioxideCephalon, Inc.NDACurrent
63459-601TrisenoxArsenic TrioxideCephalon, Inc.NDACurrent
63459-601TrisenoxArsenic TrioxideCephalon, Inc.NDACurrent
63459-601TrisenoxArsenic TrioxideCephalon, Inc.NDACurrent
63459-601TrisenoxArsenic TrioxideCephalon, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
64959SUPPL2020-10-21
64951SUPPL2020-10-21
59154SUPPL2019-06-21
59147SUPPL2019-06-21
51070SUPPL2018-01-17
51058SUPPL2018-01-17
4756SUPPL2015-02-24
14729SUPPL2015-02-23
36449SUPPL2010-07-30
14728SUPPL2010-07-30
27197SUPPL2010-07-28
4755SUPPL2010-07-28
42052ORIG2001-07-12
27196ORIG2000-09-25
14727ORIG2000-09-25