Application 021358

Type
NDA
Sponsor
BRACCO

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001MULTIHANCE MULTIPACKGADOBENATE DIMEGLUMINEINJECTABLE;INTRAVENOUS26.45GM/50ML (529MG/ML)YesYes
002MULTIHANCE MULTIPACKGADOBENATE DIMEGLUMINEINJECTABLE;INTRAVENOUS52.9GM/100ML (529MG/ML)YesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N021358-001MULTIHANCE MULTIPACKGADOBENATE DIMEGLUMINE26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23
N021358-002MULTIHANCE MULTIPACKGADOBENATE DIMEGLUMINE52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23011fe1cb6892…
2026-02-19 14:30 UTC2026-02N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-2331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-2331067a03dcf5…
2025-08-23 18:47 UTC2025-08N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-236a471c1ec25d…
2025-08-23 18:47 UTC2025-08N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-236a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-2303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-2303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-232680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-232680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-235bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-235bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23d06236e962d9…
2024-10-29 15:01 UTC2024-10N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-2379d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-2379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-231e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-231e350fbaab3a…
2024-05-31 18:47 UTC2024-05N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-238072bd15b7f6…
2024-05-31 18:47 UTC2024-05N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-238072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-235c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-235c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-235d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-235d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-234b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-234b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-2374a2ff9319b5…
2019-12-13 00:20 UTC2019-12N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-2374a2ff9319b5…
2022-03-09 01:35 UTC2022-03N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N021358-001MULTIHANCE MULTIPACK26.45GM/50ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23782e0a99824c…
2021-12-28 21:50 UTC2021-12N021358-002MULTIHANCE MULTIPACK52.9GM/100ML (529MG/ML)INJECTABLE / INTRAVENOUSRLD, RS2004-11-23782e0a99824c…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
MultiHanceGADOBENATE DIMEGLUMINEBRACCO DIAGNOSTICS INCf63abe56-46d9-4e32-afb1-f4e22370717d2025-03-16Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 021358
application number: NDA021358
ndc (product): 0270-5264

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 3 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
0270-5264MultiHancegadobenate dimeglumineBRACCO DIAGNOSTICS INCNDACurrent
0270-5264MultiHancegadobenate dimeglumineBRACCO DIAGNOSTICS INCNDACurrent
0270-5264MultiHancegadobenate dimeglumineBRACCO DIAGNOSTICS INCNDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
81497SUPPL 2025-03-07
81496SUPPL 2025-03-07
81451SUPPL 2025-03-06
79419SUPPL 2024-08-16
79407SUPPL 2024-08-16
79204SUPPL 2024-07-24
79188SUPPL 2024-07-24
77354SUPPL 2024-01-30
77337SUPPL 2024-01-29
56864SUPPL2018-12-20
56437SUPPL2018-11-14
56309SUPPL2018-11-06
53904SUPPL2018-05-01
53902SUPPL2018-05-01
53833SUPPL2018-04-27
53831SUPPL2018-04-27
51869SUPPL2018-01-26
51342SUPPL2018-01-19
49781SUPPL2017-09-19
49770SUPPL2017-09-18
36750SUPPL2013-08-09
5160SUPPL2013-08-01
36749SUPPL2012-07-10
27582SUPPL2012-07-09
5159SUPPL2011-10-03
15285SUPPL2011-02-24
5158SUPPL2011-02-18
15284SUPPL2007-09-06
5157SUPPL2007-09-06
44118ORIG2006-06-09
21615ORIG2005-04-17
36748ORIG2005-01-26
27581ORIG2004-12-02