Application 073289

Type: ANDA
Sponsor: YAOPHARMA CO LTD

Application Products#

Product, Drug, Ingredient table
Product	Drug	Ingredient	Form	Strength	Reference drug	Reference standard
001	METOPROLOL TARTRATE	METOPROLOL TARTRATE	TABLET;ORAL	100MG	No	No

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
A073289-001	METOPROLOL TARTRATE	METOPROLOL TARTRATE	100MG	TABLET / ORAL			1994-03-25

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 43 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Approval date	Source SHA-256
2026-09-14 22:38:34	2026-08	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`f41ea6bd6efb…`

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 6 of 9 · 171 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
METOPROLOL TARTRATE	METOPROLOL TARTRATE	A-S Medication Solutions	f56a17b5-3a2e-4f77-89e0-e4a41d802031	2025-06-06	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	A-S Medication Solutions	a2add754-0bd9-4f8a-ae05-b06d35d7f423	2025-06-06	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	A-S Medication Solutions	d124cdfe-8250-41c1-badb-874b1060f735	2025-06-06	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	Coupler LLC	3698837b-c34b-569a-e063-6394a90a167c	2025-06-02	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	A-S Medication Solutions	73563f90-4d1c-450b-b4d9-d39a1e39dcfd	2025-05-29	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	A-S Medication Solutions	0882d731-719d-4484-b2c8-88b04a4af67f	2025-05-28	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	A-S Medication Solutions	b5645b28-d4b7-4671-a0c1-5e093f68f823	2025-05-28	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
LOPRESSOR	METOPROLOL TARTRATE	VALIDUS PHARMACEUTICALS LLC	9f448171-9588-4a54-88b3-5d870060ce86	2025-05-15	Warnings, Adverse reactions	Name fallback generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	FOSUN PHARMA USA INC	1e787808-b3e0-417a-b333-80619d15432b	2025-04-30	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	NuCare Pharmaceuticals, Inc.	2760fbbc-ec68-4df8-e063-6394a90a15f5	2025-04-03	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOROPROLOL TARTRATE	Hikma Pharmaceuticals USA Inc.	c7ec36bb-bc6f-42de-9974-a50ac13e9410	2025-03-26	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	Asclemed USA, Inc.	e3de56de-b707-405e-bf97-837070e5c744	2025-03-18	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	Preferred Pharmaceuticals Inc.	3ced6d8c-8a88-47dc-9f11-dddbd4c31609	2025-03-06	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	Cardinal Health 107, LLC	17dbdf5f-d032-472a-9568-67689b08ef09	2025-03-05	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	Proficient Rx LP	de781298-37cb-4c03-8431-b6d86ffbde0d	2025-03-01	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	Bryant Ranch Prepack	dce119e6-8909-41d1-8919-819b820ab68c	2025-01-31	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	Bryant Ranch Prepack	bac92e34-efe3-4c20-a7bd-6a5382459f9c	2025-01-29	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	Bryant Ranch Prepack	bf81fdaa-a3e3-46d6-a8a2-3d9c6c508777	2025-01-29	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	Bryant Ranch Prepack	ef003386-bfda-426e-9eb3-055035c29307	2025-01-29	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	RedPharm Drug, Inc	fcb2812b-37d2-de88-e053-6394a90ac2b5	2025-01-23	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 1 matching rows.

NDC, Name, Nonproprietary name table
NDC	Name	Nonproprietary name	Labeler	Marketing category	Status
67046-477	Metoprolol Tartrate	Metoprolol Tartrate	Contract Pharmacy Services-PA	ANDA	Current