Application 073289

Type: ANDA
Sponsor: YAOPHARMA CO LTD

Application Products#

Product, Drug, Ingredient table
Product	Drug	Ingredient	Form	Strength	Reference drug	Reference standard
001	METOPROLOL TARTRATE	METOPROLOL TARTRATE	TABLET;ORAL	100MG	No	No

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
A073289-001	METOPROLOL TARTRATE	METOPROLOL TARTRATE	100MG	TABLET / ORAL			1994-03-25

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 43 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Approval date	Source SHA-256
2026-09-14 22:38:34	2026-08	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	A073289-001	METOPROLOL TARTRATE	100MG	TABLET / ORAL	1994-03-25	`f41ea6bd6efb…`

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 5 of 9 · 171 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Metoprolol Tartrate	METOPROLOL TARTRATE	QPharma Inc	85a638c3-d53c-453d-935c-fcfd31372a45	2025-12-03	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	QPharma, Inc.	c0e147a8-36a6-1e61-e053-2a95a90afd62	2025-12-01	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	A-S Medication Solutions	ae1fc2e6-cc67-4b90-9e39-d1ec4e9d6773	2025-11-02	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	A-S Medication Solutions	3911c18b-1259-4c6d-9466-73372eb7bd81	2025-11-02	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	A-S Medication Solutions	3325d1d4-84ca-4158-89ff-8c2185420ede	2025-11-02	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	A-S Medication Solutions	145355d0-6eea-4829-8756-644b6bc2ba73	2025-11-02	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	PD-Rx Pharmaceuticals, Inc.	f4a4da81-c4d0-4a00-9f08-9029b5d9b5ea	2025-10-17	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	Coupler LLC	3eee00d8-8606-e6bb-e063-6394a90a4a1e	2025-09-16	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	ProPharma Distribution	3ef0affa-a2f7-92de-e063-6294a90ad4d0	2025-09-16	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	Advagen Pharma Ltd	3ecff825-34ea-4535-b935-627bf2c13d93	2025-09-12	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
Metoprolol	METOPROLOL TARTRATE	Fresenius Kabi USA, LLC	be1c686e-37a5-4a53-945b-68a6ead35134	2025-09-12	Warnings, Adverse reactions	Name fallback generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL	NCS HealthCare of KY, LLC dba Vangard Labs	c97e7527-b44e-48ca-b6be-53999bf5554b	2025-08-21	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	Mylan Institutional Inc.	961248d5-d53c-408d-8f8f-d31885054f96	2025-07-22	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	Bryant Ranch Prepack	f8ac449a-d3b3-4f25-9e61-d91ef1230c72	2025-07-15	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	Cardinal Health 107, LLC	e93d7939-31ad-4fc5-a5f3-6d565cc6d0c1	2025-06-25	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	Bryant Ranch Prepack	2338d4c3-ec2e-47f8-83cd-f43fed3ba7fb	2025-06-23	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	Coupler LLC	37c9c12a-db53-1fd6-e063-6394a90afb92	2025-06-17	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
Metoprolol Tartrate	METOPROLOL TARTRATE	PD-Rx Pharmaceuticals, Inc.	00de1f16-f979-4dbf-aa60-246ffac8d410	2025-06-10	Warnings, Adverse reactions	Name fallback brand name: Metoprolol Tartrate generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	Preferred Pharmaceuticals Inc.	4c6c75c5-9c80-44e1-bd16-b97509c9f542	2025-06-06	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE
METOPROLOL TARTRATE	METOPROLOL TARTRATE	A-S Medication Solutions	7ac58d12-58bf-470d-8a5a-01a18c0c9209	2025-06-06	Warnings, Adverse reactions	Name fallback brand name: METOPROLOL TARTRATE generic name: METOPROLOL TARTRATE

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 1 matching rows.

NDC, Name, Nonproprietary name table
NDC	Name	Nonproprietary name	Labeler	Marketing category	Status
67046-477	Metoprolol Tartrate	Metoprolol Tartrate	Contract Pharmacy Services-PA	ANDA	Current