Application 078589

Type
ANDA
Sponsor
ACTAVIS TOTOWA

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001IRINOTECAN HYDROCHLORIDEIRINOTECAN HYDROCHLORIDEINJECTABLE;INJECTION40MG/2ML (20MG/ML)NoNo
002IRINOTECAN HYDROCHLORIDEIRINOTECAN HYDROCHLORIDEINJECTABLE;INJECTION100MG/5ML (20MG/ML)NoNo
003IRINOTECAN HYDROCHLORIDEIRINOTECAN HYDROCHLORIDEINJECTABLE;INJECTION500MG/25ML (20MG/ML)NoNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A078589-001IRINOTECAN HYDROCHLORIDEIRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27
A078589-002IRINOTECAN HYDROCHLORIDEIRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27
A078589-003IRINOTECAN HYDROCHLORIDEIRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-18

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-productTE code
A078589-001AP
A078589-002AP
A078589-003AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02A078589-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27011fe1cb6892…
2026-02-19 14:30 UTC2026-02A078589-003IRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-18011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A078589-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A078589-003IRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-1831067a03dcf5…
2025-08-23 18:47 UTC2025-08A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08A078589-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-276a471c1ec25d…
2025-08-23 18:47 UTC2025-08A078589-003IRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-186a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A078589-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A078589-003IRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-18fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A078589-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A078589-003IRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-18b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A078589-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A078589-003IRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-1803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-272680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A078589-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-272680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A078589-003IRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-182680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-275bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A078589-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-275bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A078589-003IRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-185bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A078589-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A078589-003IRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-18d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27d06236e962d9…
2024-10-29 15:01 UTC2024-10A078589-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27d06236e962d9…
2024-10-29 15:01 UTC2024-10A078589-003IRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-18d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A078589-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-2779d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A078589-003IRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-1879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A078589-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-27301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A078589-003IRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-18301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-271e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A078589-002IRINOTECAN HYDROCHLORIDE100MG/5ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-271e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A078589-003IRINOTECAN HYDROCHLORIDE500MG/25ML (20MG/ML)INJECTABLE / INJECTIONAP2015-11-181e350fbaab3a…
2024-05-31 18:47 UTC2024-05A078589-001IRINOTECAN HYDROCHLORIDE40MG/2ML (20MG/ML)INJECTABLE / INJECTIONAP2008-02-278072bd15b7f6…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 123 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A078589-001AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A078589-002AP1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A078589-003AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A078589-001AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A078589-002AP131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A078589-003AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A078589-001AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A078589-002AP16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A078589-003AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A078589-001AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A078589-002AP1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A078589-003AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A078589-001AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A078589-002AP1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A078589-003AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A078589-001AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A078589-002AP103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A078589-003AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A078589-001AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A078589-002AP12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A078589-003AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A078589-001AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A078589-002AP15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A078589-003AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A078589-001AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A078589-002AP1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A078589-003AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A078589-001AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A078589-002AP1d06236e962d9…
2024-10-29 15:01 UTC2024-10A078589-003AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A078589-001AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A078589-002AP179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A078589-003AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A078589-001AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A078589-002AP1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A078589-003AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A078589-001AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A078589-002AP11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A078589-003AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A078589-001AP18072bd15b7f6…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Irinotecan hydrochlorideIRINOTECAN HYDROCHLORIDEActavis Pharma, Inc.5e1fdcaa-918f-4cd8-9c7a-4c538d8661982025-05-31Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 078589
application number: ANDA078589
ndc (product): 45963-614

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 10 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
45963-614Irinotecan hydrochlorideIrinotecan hydrochlorideActavis Pharma, Inc.ANDACurrent
45963-614Irinotecan hydrochlorideIrinotecan hydrochlorideActavis Pharma, Inc.ANDACurrent
45963-614Irinotecan hydrochlorideIrinotecan hydrochlorideActavis Pharma, Inc.ANDACurrent
45963-614Irinotecan hydrochlorideIrinotecan hydrochlorideActavis Pharma, Inc.ANDACurrent
45963-614Irinotecan hydrochlorideIrinotecan hydrochlorideActavis Pharma, Inc.ANDACurrent
45963-614Irinotecan hydrochlorideIrinotecan hydrochlorideActavis Pharma, Inc.ANDACurrent
45963-614Irinotecan hydrochlorideIrinotecan hydrochlorideActavis Pharma, Inc.ANDACurrent
45963-614Irinotecan hydrochlorideIrinotecan hydrochlorideActavis Pharma, Inc.ANDACurrent
45963-614Irinotecan hydrochlorideIrinotecan hydrochlorideActavis Pharma, Inc.ANDACurrent
45963-614Irinotecan hydrochlorideIrinotecan hydrochlorideActavis Pharma, Inc.ANDACurrent