Application 202586

Type
ANDA
Sponsor
BWXT ITG

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001INDIUM IN 111 OXYQUINOLINEINDIUM IN-111 OXYQUINOLINEINJECTABLE;INJECTION1mCi/MLNoNo

Orange Book products#

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A202586-001INDIUM IN 111 OXYQUINOLINEINDIUM IN-111 OXYQUINOLINE1mCi/MLINJECTABLE / INJECTIONAP2018-07-25

Therapeutic equivalence codes#

Application-product, TE code table
Application-productTE code
A202586-001AP

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Indium In 111 OxyquinolineINDIUM IN-111 OXYQUINOLINEBWXT Medical Ltd.7dbfc0f9-0e2e-4aed-85bd-32cf7c74d4022024-11-01Warnings, Adverse reactionsExact identifier

Warnings cross-check#

openFDA text is shown for search and cross-checking; DailyMed SPL is canonical.

warnings

WARNINGS The content of the vial of indium In 111 oxyquinoline solution is intended only for use in the preparation of indium In 111 oxyquinoline labeled autologous leukocytes, and is not to be administered directly. Autologous leukocyte labeling is not recommended in leukopenic patients because of the small number of available leukocytes. Due to radiation exposure, indium In 111 oxyquinoline labeled leukocytes could cause fetal harm when administered to pregnant women. If this radiopharmaceutical is used during pregnancy, the patient should be informed of the potential hazard to the fetus. Indium In 111 oxyquinoline labeled autologous leukocytes should be used only when the benefit to be obtained exceeds the risks involved in children under eighteen years of age owing to the high radiation burden and the potential for delayed manifestation of long-term adverse effects.

Adverse reactions cross-check#

openFDA text is shown for search and cross-checking; DailyMed SPL is canonical.

adverse reactions

ADVERSE REACTIONS Sensitivity reactions (urticaria) have been reported. The presence of fever may mask pyrogenic reactions from indium In 111 oxyquinoline labeled leukocytes. The possibility of delayed adverse reactions has not been studied.

NDC Listings For This Application#

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
72536-0920Indium In 111 OxyquinolineIndium In-111 OxyquinolineBWXT ITG Canada, Inc.ANDACurrent
72536-0920Indium In 111 OxyquinolineIndium In-111 OxyquinolineBWXT Medical Ltd.ANDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
55229ORIG2018-08-20