Application 204308

Type
NDA
Sponsor
SILVERGATE PHARMS

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001EPANED KITENALAPRIL MALEATEFOR SOLUTION;ORAL1MG/MLYesNo

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N204308-001EPANED KITENALAPRIL MALEATE1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13

Orange Book patents#

Current patent rows page 1 of 1 · 12 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N204308-00185687472032-11-06Drug product2013-10-31
N204308-00187783662032-11-06U-17232014-07-16
N204308-00187783662032-11-06U-1852014-07-16
N204308-00187783662032-11-06U-18922014-07-16
N204308-00187783662032-11-06U-32014-07-16
N204308-00187783662032-11-06U-712014-07-16
N204308-00198552142032-11-06Drug product2018-01-10
N204308-00199685532032-11-06U-17232018-06-01
N204308-00199685532032-11-06U-1852018-06-01
N204308-00199685532032-11-06U-18922018-06-01
N204308-00199685532032-11-06U-32018-06-01
N204308-00199685532032-11-06U-712018-06-01

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-1331067a03dcf5…
2025-08-23 18:47 UTC2025-08N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-136a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-1303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-132680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-135bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-1379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-131e350fbaab3a…
2024-05-31 18:47 UTC2024-05N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-138072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-135c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-135d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-134b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-1374a2ff9319b5…
2022-03-09 01:35 UTC2022-03N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or efficacy reasons**FOR SOLUTION / ORALRLD2013-08-13782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-1387673890dc5c…
2021-03-12 10:30 UTC2021-03N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-135aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-138869cabd3fbd…
2020-11-12 02:37 UTC2020-11N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-13c0c555d07b60…
2019-12-14 00:12 UTC2019-12N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-133f01610625f2…
2019-09-15 20:21 UTC2019-09N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-13b00525d2431f…
2019-07-19 19:46 UTC2019-07N204308-001EPANED KIT1MG/MLFOR SOLUTION / ORALRLD2013-08-13ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-136a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-131c564ffb4f44…
2023-12-20 04:57 UTC2023-12N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-139b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-133f0d92c62455…
2023-05-13 08:27 UTC2023-05N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13053a50430f4f…
2023-01-26 05:58 UTC2023-01N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-133bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-133a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N204308-001EPANED KIT1MG/ML **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**FOR SOLUTION / ORALRLD2013-08-13e64feba35796…

Observed Orange Book patent history#

Patent history page 1 of 13 · 504 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N204308-00185687472032-11-06Drug product2013-10-31caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00187783662032-11-06U-32014-07-16caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00187783662032-11-06U-712014-07-16caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00187783662032-11-06U-1852014-07-16caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00187783662032-11-06U-17232014-07-16caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00187783662032-11-06U-18922014-07-16caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00198552142032-11-06Drug product2018-01-10caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00199685532032-11-06U-712018-06-01caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00199685532032-11-06U-32018-06-01caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00199685532032-11-06U-18922018-06-01caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00199685532032-11-06U-1852018-06-01caaa826d4ba7…
2026-08-18 06:07:402026-07N204308-00199685532032-11-06U-17232018-06-01caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N204308-00185687472032-11-06Drug product2013-10-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00187783662032-11-06U-32014-07-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00187783662032-11-06U-712014-07-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00187783662032-11-06U-1852014-07-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00187783662032-11-06U-17232014-07-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00187783662032-11-06U-18922014-07-16011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00198552142032-11-06Drug product2018-01-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00199685532032-11-06U-712018-06-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00199685532032-11-06U-32018-06-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00199685532032-11-06U-18922018-06-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00199685532032-11-06U-1852018-06-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N204308-00199685532032-11-06U-17232018-06-01011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00185687472032-11-06Drug product2013-10-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00187783662032-11-06U-32014-07-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00187783662032-11-06U-712014-07-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00187783662032-11-06U-1852014-07-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00187783662032-11-06U-17232014-07-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00187783662032-11-06U-18922014-07-1631067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00198552142032-11-06Drug product2018-01-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00199685532032-11-06U-712018-06-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00199685532032-11-06U-32018-06-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00199685532032-11-06U-18922018-06-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00199685532032-11-06U-1852018-06-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N204308-00199685532032-11-06U-17232018-06-0131067a03dcf5…
2025-08-23 18:47 UTC2025-08N204308-00185687472032-11-06Drug product2013-10-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N204308-00187783662032-11-06U-32014-07-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N204308-00187783662032-11-06U-712014-07-166a471c1ec25d…
2025-08-23 18:47 UTC2025-08N204308-00187783662032-11-06U-1852014-07-166a471c1ec25d…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 4 · 66 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Enalapril MaleateENALAPRIL MALEATEREMEDYREPACK INC.1b464099-491d-473b-836e-9d86b2b1eeec2026-08-11Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril MaleateENALAPRIL MALEATEBryant Ranch Prepackfb3c7066-76cb-4e8e-b98b-bcb41a3631df2026-08-11Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
ENALAPRIL MALEATEENALAPRIL MALEATEBryant Ranch Prepackfa93d8e6-2ed2-4a3c-bf6d-33bd0a374efa2026-08-04Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
ENALAPRIL MALEATEENALAPRIL MALEATEPreferred Pharmaceuticals Inc.b31372f7-cda3-4ead-a481-4cde62e843fd2026-07-23Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril MaleateENALAPRIL MALEATEREMEDYREPACK INC.e47afc0d-afc4-4972-a28a-5d3c640390ab2026-07-21Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril MaleateENALAPRIL MALEATESun Pharmaceutical Industries, Inc.f103b9f9-e081-419d-a2d8-b86acda834dd2026-07-14Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
ENALAPRIL MALEATEENALAPRIL MALEATEPreferred Pharmaceuticals Inc.eee8633b-9d9e-453d-8c6b-8b13c94d2f582026-07-10Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
ENALAPRIL MALEATEENALAPRIL MALEATEScieGen Pharmaceuticals, Inc.63187a94-9ac7-4320-ac70-0631e08c2b8d2026-06-25Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril MaleateENALAPRIL MALEATESt. Mary's Medical Park Pharmacyed266486-e4a5-9dd1-e053-2a95a90a80d32026-06-22Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
ENALAPRIL MALEATEENALAPRIL MALEATEBryant Ranch Prepackc1e4cd79-ece5-432c-bd3a-ed4633ccec702026-05-27Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril MaleateENALAPRIL MALEATECoupler LLC508a58fa-9f66-e984-e063-6394a90a296a2026-04-28Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril MaleateENALAPRIL MALEATEPreferred Pharmaceuticals Inc.5596ba00-4a1c-4503-99db-3a9617ed17c02026-04-10Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril MaleateENALAPRIL MALEATEPreferred Pharmaceuicals Inc.898b36d6-320f-4d6c-9734-0be8363dc3d72026-04-10Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril MaleateENALAPRIL MALEATEPreferred Pharmaceuticals Inc.9e277302-6e6c-4a95-8f25-aaff64fb0b822026-04-10Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril maleateENALAPRIL MALEATEA-S Medication Solutions9f913e79-fe6d-4ff2-9f8e-eef9df689fa82026-03-17Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril MaleateENALAPRIL MALEATENuCare Pharmaceuticals, Inc.315baaa6-512c-f27b-e063-6294a90a2c912026-03-12Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril maleateENALAPRIL MALEATELegacy Pharmaceutical Packaging, LLCed7536f1-9a7d-4519-e053-2a95a90a4a652026-03-11Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril MaleateENALAPRIL MALEATEBryant Ranch Prepack7fdc2d8a-9b5d-43c4-b32f-6f2505aee33c2026-03-06Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril MaleateENALAPRIL MALEATEBryant Ranch Prepack2a8ca159-c4c7-468a-bcc2-d1b879ea2c7e2026-02-16Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE
Enalapril MaleateENALAPRIL MALEATESolco Healthcare US, LLC0c829189-fba2-48f8-a23f-d5471a0345f62026-01-31Boxed warning, Warnings, Adverse reactionsName fallback
generic name: ENALAPRIL MALEATE

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 2 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
52652-1001EPANEDenalapril maleateSilvergate Pharmaceuticals, Inc.NDACurrent
52652-1001EPANEDenalapril maleateSilvergate Pharmaceuticals, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
49184SUPPL2017-08-02
49152SUPPL2017-07-31
47679SUPPL2017-03-24
47655SUPPL2017-03-23
40374SUPPL2016-02-02
10321SUPPL2016-01-29
19544SUPPL2014-09-09
19543SUPPL2014-09-09
32542SUPPL2014-09-08
10320SUPPL2014-09-08
24466ORIG2014-06-27
22951ORIG2014-06-27
40373ORIG2013-08-15
10319ORIG2013-08-15