Application 205388

Type
NDA
Sponsor
OMEROS

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001OMIDRIAKETOROLAC TROMETHAMINE; PHENYLEPHRINE HYDROCHLORIDESOLUTION;IRRIGATIONEQ 0.3% BASE;EQ 1% BASEYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N205388-001OMIDRIAKETOROLAC TROMETHAMINE; PHENYLEPHRINE HYDROCHLORIDEEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
N205388-001AT

Orange Book patents#

Current patent rows page 1 of 1 · 5 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N205388-00190668562033-10-23Drug product2015-07-13
N205388-00194864062033-10-23Drug product2016-11-09
N205388-00198552462033-10-23Drug product2018-01-05
N205388-0019066856*PED2034-04-23Pediatric extension
N205388-0019486406*PED2034-04-23Pediatric extension

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-3079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-301e350fbaab3a…
2024-05-31 18:47 UTC2024-05N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-308072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-305c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-305d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-304b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-3074a2ff9319b5…
2022-03-09 01:35 UTC2022-03N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-3087673890dc5c…
2021-03-12 10:30 UTC2021-03N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-305aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-308869cabd3fbd…
2020-11-12 02:37 UTC2020-11N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30c0c555d07b60…
2019-12-14 00:12 UTC2019-12N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-303f01610625f2…
2019-09-15 20:21 UTC2019-09N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30b00525d2431f…
2019-07-19 19:46 UTC2019-07N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-306a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-301c564ffb4f44…
2023-12-20 04:57 UTC2023-12N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-309b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-303f0d92c62455…
2023-05-13 08:27 UTC2023-05N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30053a50430f4f…
2023-01-26 05:58 UTC2023-01N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-303bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-303a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N205388-001OMIDRIAEQ 0.3% BASE;EQ 1% BASESOLUTION / IRRIGATIONATRLD, RS2014-05-30e64feba35796…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N205388-001AT1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N205388-001AT1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205388-001AT131067a03dcf5…
2025-08-23 18:47 UTC2025-08N205388-001AT16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205388-001AT1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205388-001AT1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205388-001AT103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205388-001AT12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N205388-001AT15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N205388-001AT1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N205388-001AT1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N205388-001AT179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N205388-001AT1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N205388-001AT11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N205388-001AT18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N205388-001AT15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N205388-001AT15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N205388-001AT14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N205388-001AT174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N205388-001AT1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N205388-001AT1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N205388-001AT187673890dc5c…
2021-03-12 10:30 UTC2021-03N205388-001AT15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N205388-001AT18869cabd3fbd…
2020-11-12 02:37 UTC2020-11N205388-001AT1c0c555d07b60…
2019-12-14 00:12 UTC2019-12N205388-001AT13f01610625f2…
2019-09-15 20:21 UTC2019-09N205388-001AT1b00525d2431f…
2019-07-19 19:46 UTC2019-07N205388-001AT1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N205388-001AT16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N205388-001AT11c564ffb4f44…
2023-12-20 04:57 UTC2023-12N205388-001AT1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N205388-001AT1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N205388-001AT19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N205388-001AT1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N205388-001AT13f0d92c62455…
2023-05-13 08:27 UTC2023-05N205388-001AT1053a50430f4f…
2023-01-26 05:58 UTC2023-01N205388-001AT13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N205388-001AT13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N205388-001AT1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N205388-001AT1e64feba35796…

Observed Orange Book patent history#

Patent history page 1 of 12 · 446 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-08-18 06:07:402026-07N205388-00190668562033-10-23Drug product2015-07-13caaa826d4ba7…
2026-08-18 06:07:402026-07N205388-00194864062033-10-23Drug product2016-11-09caaa826d4ba7…
2026-08-18 06:07:402026-07N205388-00198552462033-10-23Drug product2018-01-05caaa826d4ba7…
2026-08-18 06:07:402026-07N205388-0019066856*PED2034-04-23Pediatric extensioncaaa826d4ba7…
2026-08-18 06:07:402026-07N205388-0019486406*PED2034-04-23Pediatric extensioncaaa826d4ba7…
2026-02-19 14:30 UTC2026-02N205388-00190668562033-10-23Drug product2015-07-13011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205388-00194864062033-10-23Drug product2016-11-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205388-00198552462033-10-23Drug product2018-01-05011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205388-0019066856*PED2034-04-23Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205388-0019486406*PED2034-04-23Pediatric extension011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205388-00190668562033-10-23Drug product2015-07-1331067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205388-00194864062033-10-23Drug product2016-11-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205388-00198552462033-10-23Drug product2018-01-0531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205388-0019066856*PED2034-04-23Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205388-0019486406*PED2034-04-23Pediatric extension31067a03dcf5…
2025-08-23 18:47 UTC2025-08N205388-00190668562033-10-23Drug product2015-07-136a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205388-00194864062033-10-23Drug product2016-11-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205388-00198552462033-10-23Drug product2018-01-056a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205388-0019066856*PED2034-04-23Pediatric extension6a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205388-0019486406*PED2034-04-23Pediatric extension6a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205388-00190668562033-10-23Drug product2015-07-13fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205388-00194864062033-10-23Drug product2016-11-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205388-00198552462033-10-23Drug product2018-01-05fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205388-0019066856*PED2034-04-23Pediatric extensionfd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205388-0019486406*PED2034-04-23Pediatric extensionfd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205388-00190668562033-10-23Drug product2015-07-13b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205388-00194864062033-10-23Drug product2016-11-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205388-00198552462033-10-23Drug product2018-01-05b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205388-0019066856*PED2034-04-23Pediatric extensionb8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N205388-0019486406*PED2034-04-23Pediatric extensionb8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205388-0018173707*PED2024-01-30Pediatric extension03ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205388-0018586633*PED2024-01-30Pediatric extension03ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205388-0019278101*PED2024-01-30Pediatric extension03ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205388-0019399040*PED2024-01-30Pediatric extension03ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205388-00190668562033-10-23Drug product2015-07-1303ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205388-00194864062033-10-23Drug product2016-11-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205388-00198552462033-10-23Drug product2018-01-0503ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205388-0019066856*PED2034-04-23Pediatric extension03ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N205388-0019486406*PED2034-04-23Pediatric extension03ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N205388-0018173707*PED2024-01-30Pediatric extension2680178bc6a6…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2019-12-13 00:20 UTC2019-12N205388-001NPP2020-12-0874a2ff9319b5…
2019-12-13 00:20 UTC2019-12N205388-001PED2021-06-0874a2ff9319b5…
2021-12-28 21:50 UTC2021-12N205388-001PED2021-06-08782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N205388-001PED2021-06-0887673890dc5c…
2021-03-12 10:30 UTC2021-03N205388-001PED2021-06-085aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N205388-001NPP2020-12-088869cabd3fbd…
2020-12-22 03:56 UTC2020-12N205388-001PED2021-06-088869cabd3fbd…
2020-11-12 02:37 UTC2020-11N205388-001NPP2020-12-08c0c555d07b60…
2020-11-12 02:37 UTC2020-11N205388-001PED2021-06-08c0c555d07b60…
2019-12-14 00:12 UTC2019-12N205388-001NPP2020-12-083f01610625f2…
2019-12-14 00:12 UTC2019-12N205388-001PED2021-06-083f01610625f2…
2019-09-15 20:21 UTC2019-09N205388-001NPP2020-12-08b00525d2431f…
2019-09-15 20:21 UTC2019-09N205388-001PED2021-06-08b00525d2431f…
2019-07-19 19:46 UTC2019-07N205388-001NPP2020-12-08ea99ee380514…
2019-07-19 19:46 UTC2019-07N205388-001PED2021-06-08ea99ee380514…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
OmidriaPHENYLEPHRINE AND KETOROLACOmeros Corporation21470688-4e81-4ea5-ac38-f72e10552e7e2026-04-08Warnings, Adverse reactionsExact identifier
application applno (NDA): 205388
application number: NDA205388
ndc (product): 62225-600
OmidriaPHENYLEPHRINE AND KETOROLACRayner Surgical Inc.f25d7a42-da2a-7310-e053-2995a90a590f2023-07-07Warnings, Adverse reactionsExact identifier
application applno (NDA): 205388
application number: NDA205388

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 2 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
62225-600Omidriaphenylephrine and ketorolacOmeros CorporationNDACurrent
62225-600Omidriaphenylephrine and ketorolacOmeros CorporationNDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
50778SUPPL2017-12-20
50654SUPPL2017-12-11
19641SUPPL2016-06-24
24493ORIG2014-12-09
22986ORIG2014-12-09
32666ORIG2014-06-03
19640ORIG2014-06-03
51555SUPPL1900-01-01
51554SUPPL1900-01-01
51553SUPPL1900-01-01