Application 205776

Type
NDA
Sponsor
MEDEXUS

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001RASUVOMETHOTREXATESOLUTION;SUBCUTANEOUS7.5MG/0.15ML (7.5MG/0.15ML)YesYes
002RASUVOMETHOTREXATESOLUTION;SUBCUTANEOUS10MG/0.20ML (10MG/0.20ML)YesYes
003RASUVOMETHOTREXATESOLUTION;SUBCUTANEOUS12.5MG/0.25ML (12.5MG/0.25ML)YesYes
004RASUVOMETHOTREXATESOLUTION;SUBCUTANEOUS15MG/0.30ML (15MG/0.30ML)YesYes
005RASUVOMETHOTREXATESOLUTION;SUBCUTANEOUS17.5MG/0.35ML (17.5MG/0.35ML)YesYes
006RASUVOMETHOTREXATESOLUTION;SUBCUTANEOUS20MG/0.4ML (20MG/0.4ML)YesYes
007RASUVOMETHOTREXATESOLUTION;SUBCUTANEOUS22.5MG/0.45ML (22.5MG/0.45ML)YesYes
008RASUVOMETHOTREXATESOLUTION;SUBCUTANEOUS25MG/0.5ML (25MG/0.5ML)YesYes
009RASUVOMETHOTREXATESOLUTION;SUBCUTANEOUS27.5MG/0.55ML (27.5MG/0.55ML)YesNo
010RASUVOMETHOTREXATESOLUTION;SUBCUTANEOUS30MG/0.6ML (30MG/0.6ML)YesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 10 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N205776-001RASUVOMETHOTREXATE7.5MG/0.15ML (7.5MG/0.15ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10
N205776-002RASUVOMETHOTREXATE10MG/0.20ML (10MG/0.20ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10
N205776-003RASUVOMETHOTREXATE12.5MG/0.25ML (12.5MG/0.25ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10
N205776-004RASUVOMETHOTREXATE15MG/0.30ML (15MG/0.30ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10
N205776-005RASUVOMETHOTREXATE17.5MG/0.35ML (17.5MG/0.35ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10
N205776-006RASUVOMETHOTREXATE20MG/0.4ML (20MG/0.4ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10
N205776-007RASUVOMETHOTREXATE22.5MG/0.45ML (22.5MG/0.45ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10
N205776-008RASUVOMETHOTREXATE25MG/0.5ML (25MG/0.5ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10
N205776-009RASUVOMETHOTREXATE27.5MG/0.55ML (27.5MG/0.55ML)SOLUTION / SUBCUTANEOUSRLD2014-07-10
N205776-010RASUVOMETHOTREXATE30MG/0.6ML (30MG/0.6ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10

Orange Book patents#

Current patent rows page 1 of 1 · 10 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N205776-00186642312029-06-01U-14422014-07-31
N205776-00286642312029-06-01U-14422014-07-31
N205776-00386642312029-06-01U-14422014-07-31
N205776-00486642312029-06-01U-14422014-07-31
N205776-00586642312029-06-01U-14422014-07-31
N205776-00686642312029-06-01U-14422014-07-31
N205776-00786642312029-06-01U-14422014-07-31
N205776-00886642312029-06-01U-14422014-07-31
N205776-00986642312029-06-01U-14422014-07-31
N205776-01086642312029-06-01U-14422014-07-31

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 11 · 410 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N205776-001RASUVO7.5MG/0.15ML (7.5MG/0.15ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-002RASUVO10MG/0.20ML (10MG/0.20ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-003RASUVO12.5MG/0.25ML (12.5MG/0.25ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-004RASUVO15MG/0.30ML (15MG/0.30ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-005RASUVO17.5MG/0.35ML (17.5MG/0.35ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-006RASUVO20MG/0.4ML (20MG/0.4ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-007RASUVO22.5MG/0.45ML (22.5MG/0.45ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-008RASUVO25MG/0.5ML (25MG/0.5ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-009RASUVO27.5MG/0.55ML (27.5MG/0.55ML)SOLUTION / SUBCUTANEOUSRLD2014-07-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-010RASUVO30MG/0.6ML (30MG/0.6ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-001RASUVO7.5MG/0.15ML (7.5MG/0.15ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-002RASUVO10MG/0.20ML (10MG/0.20ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-003RASUVO12.5MG/0.25ML (12.5MG/0.25ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-004RASUVO15MG/0.30ML (15MG/0.30ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-005RASUVO17.5MG/0.35ML (17.5MG/0.35ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-006RASUVO20MG/0.4ML (20MG/0.4ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-007RASUVO22.5MG/0.45ML (22.5MG/0.45ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-008RASUVO25MG/0.5ML (25MG/0.5ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-009RASUVO27.5MG/0.55ML (27.5MG/0.55ML)SOLUTION / SUBCUTANEOUSRLD2014-07-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-010RASUVO30MG/0.6ML (30MG/0.6ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-1031067a03dcf5…
2025-08-23 18:47 UTC2025-08N205776-001RASUVO7.5MG/0.15ML (7.5MG/0.15ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-002RASUVO10MG/0.20ML (10MG/0.20ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-003RASUVO12.5MG/0.25ML (12.5MG/0.25ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-004RASUVO15MG/0.30ML (15MG/0.30ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-005RASUVO17.5MG/0.35ML (17.5MG/0.35ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-006RASUVO20MG/0.4ML (20MG/0.4ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-007RASUVO22.5MG/0.45ML (22.5MG/0.45ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-008RASUVO25MG/0.5ML (25MG/0.5ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-009RASUVO27.5MG/0.55ML (27.5MG/0.55ML)SOLUTION / SUBCUTANEOUSRLD2014-07-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-010RASUVO30MG/0.6ML (30MG/0.6ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-106a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-001RASUVO7.5MG/0.15ML (7.5MG/0.15ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-002RASUVO10MG/0.20ML (10MG/0.20ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-003RASUVO12.5MG/0.25ML (12.5MG/0.25ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-004RASUVO15MG/0.30ML (15MG/0.30ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-005RASUVO17.5MG/0.35ML (17.5MG/0.35ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-006RASUVO20MG/0.4ML (20MG/0.4ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-007RASUVO22.5MG/0.45ML (22.5MG/0.45ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-008RASUVO25MG/0.5ML (25MG/0.5ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-009RASUVO27.5MG/0.55ML (27.5MG/0.55ML)SOLUTION / SUBCUTANEOUSRLD2014-07-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-010RASUVO30MG/0.6ML (30MG/0.6ML)SOLUTION / SUBCUTANEOUSRLD, RS2014-07-10fd3edfee7708…

Observed Orange Book patent history#

Patent history page 1 of 11 · 410 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N205776-00186642312029-06-01U-14422014-07-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-00286642312029-06-01U-14422014-07-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-00386642312029-06-01U-14422014-07-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-00486642312029-06-01U-14422014-07-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-00586642312029-06-01U-14422014-07-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-00686642312029-06-01U-14422014-07-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-00786642312029-06-01U-14422014-07-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-00886642312029-06-01U-14422014-07-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-00986642312029-06-01U-14422014-07-31011fe1cb6892…
2026-02-19 14:30 UTC2026-02N205776-01086642312029-06-01U-14422014-07-31011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-00186642312029-06-01U-14422014-07-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-00286642312029-06-01U-14422014-07-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-00386642312029-06-01U-14422014-07-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-00486642312029-06-01U-14422014-07-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-00586642312029-06-01U-14422014-07-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-00686642312029-06-01U-14422014-07-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-00786642312029-06-01U-14422014-07-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-00886642312029-06-01U-14422014-07-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-00986642312029-06-01U-14422014-07-3131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N205776-01086642312029-06-01U-14422014-07-3131067a03dcf5…
2025-08-23 18:47 UTC2025-08N205776-00186642312029-06-01U-14422014-07-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-00286642312029-06-01U-14422014-07-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-00386642312029-06-01U-14422014-07-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-00486642312029-06-01U-14422014-07-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-00586642312029-06-01U-14422014-07-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-00686642312029-06-01U-14422014-07-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-00786642312029-06-01U-14422014-07-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-00886642312029-06-01U-14422014-07-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-00986642312029-06-01U-14422014-07-316a471c1ec25d…
2025-08-23 18:47 UTC2025-08N205776-01086642312029-06-01U-14422014-07-316a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-00186642312029-06-01U-14422014-07-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-00286642312029-06-01U-14422014-07-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-00386642312029-06-01U-14422014-07-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-00486642312029-06-01U-14422014-07-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-00586642312029-06-01U-14422014-07-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-00686642312029-06-01U-14422014-07-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-00786642312029-06-01U-14422014-07-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-00886642312029-06-01U-14422014-07-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-00986642312029-06-01U-14422014-07-31fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N205776-01086642312029-06-01U-14422014-07-31fd3edfee7708…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
RasuvoMETHOTREXATEMedexus Pharma Inc.d0075461-0e7e-4967-9c9b-d6440e912c0e2025-12-15Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 205776
application number: NDA205776
ndc (product): 59137-515
ndc (product): 59137-530
ndc (product): 59137-520
ndc (product): 59137-510
ndc (product): 59137-505
ndc (product): 59137-535
ndc (product): 59137-540
ndc (product): 59137-525
ndc (product): 59137-550

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 18 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
59137-505RasuvomethotrexateMedexus Pharma Inc.NDACurrent
59137-505RasuvomethotrexateMedac Pharma, IncNDACurrent
59137-510RasuvomethotrexateMedexus Pharma Inc.NDACurrent
59137-510RasuvomethotrexateMedac Pharma, IncNDACurrent
59137-515RasuvomethotrexateMedexus Pharma Inc.NDACurrent
59137-515RasuvomethotrexateMedac Pharma, IncNDACurrent
59137-520RasuvomethotrexateMedexus Pharma Inc.NDACurrent
59137-520RasuvomethotrexateMedac Pharma, IncNDACurrent
59137-525RasuvomethotrexateMedexus Pharma Inc.NDACurrent
59137-525RasuvomethotrexateMedac Pharma, IncNDACurrent
59137-530RasuvomethotrexateMedexus Pharma Inc.NDACurrent
59137-530RasuvomethotrexateMedac Pharma, IncNDACurrent
59137-535RasuvomethotrexateMedexus Pharma Inc.NDACurrent
59137-535RasuvomethotrexateMedac Pharma, IncNDACurrent
59137-540RasuvomethotrexateMedexus Pharma Inc.NDACurrent
59137-540RasuvomethotrexateMedac Pharma, IncNDACurrent
59137-550RasuvomethotrexateMedexus Pharma Inc.NDACurrent
59137-550RasuvomethotrexateMedac Pharma, IncNDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
62135SUPPL2020-03-12
62133SUPPL2020-03-12
53063SUPPL2018-03-20
53045SUPPL2018-03-16
19683SUPPL2015-08-25
10500SUPPL2015-08-25
23001ORIG2015-04-13
19682ORIG2014-07-11
10499ORIG2014-07-11