Application 206321

Type: NDA
Sponsor: NOVO

Application Products#

Product, Drug, Ingredient table
Product	Drug	Ingredient	Form	Strength	Reference drug	Reference standard
001	SAXENDA	LIRAGLUTIDE RECOMBINANT	SOLUTION;SUBCUTANEOUS	18MG/3ML (6MG/ML)	Yes	Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
N206321-001	SAXENDA	LIRAGLUTIDE	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS	AP2	RLD, RS	2014-12-23

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-product	TE code
N206321-001	AP2

Orange Book patents#

Current patent rows page 1 of 1 · 4 matching rows.

Application-product, Patent, Expiration table
Application-product	Patent	Expiration	Use code	Coverage / status	Submission date
N206321-001	8114833	2025-08-13		Drug product	2015-01-21
N206321-001	8114833*PED	2026-02-13		Pediatric extension
N206321-001	9968659	2037-01-09	U-2438		2018-11-16
N206321-001	9968659*PED	2037-07-09		Pediatric extension

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	RLD / RS	Approval date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS	AP2	RLD, RS	2014-12-23	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS	AP2	RLD, RS	2014-12-23	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`e64feba35796…`
2022-07-09 03:26 UTC · 3 captures of this ZIP	2022-07	N206321-001	SAXENDA	18MG/3ML (6MG/ML)	SOLUTION / SUBCUTANEOUS		RLD, RS	2014-12-23	`cb3db0bc1861…`

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N206321-001	AP2	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N206321-001	AP2	1	`31067a03dcf5…`
2026-07-26 02:55 UTC · 3 captures of this ZIP	2026-06	N206321-001	AP2	1	`a50c72e98297…`

Observed Orange Book patent history#

Patent history page 1 of 36 · 1,420 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Patent	Expiration	Use code	Coverage / status	Submission date	Source SHA-256
2026-02-19 14:30 UTC	2026-02	N206321-001	8114833	2025-08-13		Drug product	2015-01-21	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N206321-001	8114833*PED	2026-02-13		Pediatric extension		`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N206321-001	9968659	2037-01-09	U-2438		2018-11-16	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	N206321-001	9968659*PED	2037-07-09		Pediatric extension		`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N206321-001	8114833	2025-08-13		Drug product	2015-01-21	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N206321-001	8114833*PED	2026-02-13		Pediatric extension		`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N206321-001	9968659	2037-01-09	U-2438		2018-11-16	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	N206321-001	9968659*PED	2037-07-09		Pediatric extension		`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	N206321-001	8114833	2025-08-13		Drug product	2015-01-21	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N206321-001	8114833*PED	2026-02-13		Pediatric extension		`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N206321-001	9968659	2037-01-09	U-2438		2018-11-16	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	N206321-001	9968659*PED	2037-07-09		Pediatric extension		`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	8114833	2025-08-13		Drug product	2015-01-21	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	11446443	2025-10-20		Drug product	2022-10-11	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	8684969	2025-10-20		Drug product	2015-01-21	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	10357616	2026-01-20		Drug product	2019-08-08	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	10376652	2026-01-20		Drug product	2019-09-13	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	11311679	2026-01-20		Drug product	2022-05-20	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	9616180	2026-01-20		Drug product	2018-08-23	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	9861757	2026-01-20		Drug product	2018-08-23	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	9108002	2026-01-26		Drug product	2015-09-18	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	8114833*PED	2026-02-13		Pediatric extension		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	8684969*PED	2026-04-20		Pediatric extension		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	10220155	2026-07-17		Drug product	2019-04-01	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	11097063	2026-07-17		Drug product	2021-09-22	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	8920383	2026-07-17		Drug product	2015-02-05	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	9775953	2026-07-17		Drug product	2017-11-13	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	9616180*PED	2026-07-20		Pediatric extension		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	9861757*PED	2026-07-20		Pediatric extension		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	9108002*PED	2026-07-26		Pediatric extension		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	RE46363	2026-08-03		Drug product	2017-05-10	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	10220155*PED	2027-01-17		Pediatric extension		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	8920383*PED	2027-01-17		Pediatric extension		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	9775953*PED	2027-01-17		Pediatric extension		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	RE46363*PED	2027-02-03		Pediatric extension		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	9687611	2027-02-27		Drug product	2017-09-06	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	9687611*PED	2027-08-27		Pediatric extension		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	9457154	2027-09-27		Drug product	2016-10-26	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	9457154*PED	2028-03-27		Pediatric extension		`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	N206321-001	9132239	2032-02-01		Drug product	2015-09-18	`fd3edfee7708…`

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
Captured	Edition	Application-product	Exclusivity code	Expiration	Source SHA-256
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	N206321-001	NPP	2023-12-04	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	N206321-001	NPP	2023-12-04	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	N206321-001	NPP	2023-12-04	`4b0b4de00fa7…`
2022-03-09 01:35 UTC	2022-03	N206321-001	NPP	2023-12-04	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	N206321-001	NPP	2023-12-04	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	N206321-001	NPP	2023-12-04	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	N206321-001	NPP	2023-12-04	`5aa47cf7b7d7…`
2023-12-20 04:57 UTC	2023-12	N206321-001	NPP	2023-12-04	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	N206321-001	NPP	2023-12-04	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	N206321-001	NPP	2023-12-04	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	N206321-001	NPP	2023-12-04	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	N206321-001	NPP	2023-12-04	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	N206321-001	NPP	2023-12-04	`053a50430f4f…`
2023-01-26 05:58 UTC	2023-01	N206321-001	NPP	2023-12-04	`3bdfa0b2c4d7…`
2022-11-12 20:34 UTC · 5 captures of this ZIP	2022-11	N206321-001	NPP	2023-12-04	`3a93d1ddd44b…`
2022-10-28 04:53 UTC	2022-10	N206321-001	NPP	2023-12-04	`f41ea6bd6efb…`
2022-09-29 23:25 UTC	2022-09	N206321-001	NPP	2023-12-04	`e64feba35796…`
2022-07-09 03:26 UTC · 3 captures of this ZIP	2022-07	N206321-001	NPP	2023-12-04	`cb3db0bc1861…`

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Saxenda	LIRAGLUTIDE	Novo Nordisk Pharmaceutical Industries, LP	3946d389-0926-4f77-a708-0acb8153b143	2026-02-25	Boxed warning, Warnings, Adverse reactions	Exact identifier application applno (NDA): 206321 application number: NDA206321 ndc (product): 0169-2800
Saxenda	LIRAGLUTIDE	A-S Medication Solutions	7b11f6ac-4c27-4748-9e65-22d4cf3adfb4	2024-01-26	Boxed warning, Warnings, Adverse reactions	Exact identifier application applno (NDA): 206321 application number: NDA206321 ndc (product): 50090-4257

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 8 matching rows.

NDC, Name, Nonproprietary name table
NDC	Name	Nonproprietary name	Labeler	Marketing category	Status
0169-2800	Saxenda	liraglutide	Novo Nordisk	NDA	Current
0169-2800	Saxenda	liraglutide	Novo Nordisk	NDA	Current
0169-2800	Saxenda	liraglutide	Novo Nordisk	NDA	Current
0169-2800	Saxenda	liraglutide	Novo Nordisk	NDA	Current
0169-2800	Saxenda	liraglutide	Novo Nordisk	NDA	Current
0169-2800	Saxenda	liraglutide	Novo Nordisk	NDA	Current
50090-4257	Saxenda	liraglutide	A-S Medication Solutions	NDA	Current
50090-4257	Saxenda	liraglutide	A-S Medication Solutions	NDA	Current

Documents#

Document, Submission type, Date table
Document	Submission type	Date
85188	SUPPL	2026-03-02
85176	SUPPL	2026-02-27
83789	SUPPL	2025-10-15
83788	SUPPL	2025-10-15
83772	SUPPL	2025-10-15
82359	SUPPL	2025-05-30
82345	SUPPL	2025-05-29
80122	SUPPL	2024-11-05
80103	SUPPL	2024-11-04
74045	SUPPL	2023-04-24
74037	SUPPL	2023-04-21
71345	SUPPL	2022-06-16
71344	SUPPL	2022-06-16
71336	SUPPL	2022-06-16
65553	SUPPL	2020-12-09
65552	SUPPL	2020-12-09
65551	SUPPL	2020-12-09
65527	SUPPL	2020-12-08
65526	SUPPL	2020-12-08
65525	SUPPL	2020-12-08
62344	SUPPL	2020-03-26
62342	SUPPL	2020-03-26
62341	SUPPL	2020-03-26
58926	SUPPL	2019-06-03
56665	SUPPL	2018-12-07
56080	SUPPL	2018-10-23
56050	SUPPL	2018-10-22
48614	SUPPL	2017-06-01
48208	SUPPL	2017-05-02
48207	SUPPL	2017-05-02
48126	SUPPL	2017-04-27
48125	SUPPL	2017-04-27
48124	SUPPL	2017-04-27
48123	SUPPL	2017-04-27
45520	SUPPL	2016-10-12
45412	SUPPL	2016-09-29
32797	SUPPL	2016-02-02
43516	ORIG	2015-10-01
19715	SUPPL	2015-04-01
32796	SUPPL	2015-03-31
44600	ORIG	2014-12-31
40537	ORIG	2014-12-31
10560	ORIG	2014-12-31