Application 208684

Type
NDA
Sponsor
PTC THERAP

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001EMFLAZADEFLAZACORTTABLET;ORAL6MGYesNo
002EMFLAZADEFLAZACORTTABLET;ORAL18MGYesNo
003EMFLAZADEFLAZACORTTABLET;ORAL30MGYesNo
004EMFLAZADEFLAZACORTTABLET;ORAL36MGYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 4 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N208684-001EMFLAZADEFLAZACORT6MGTABLET / ORALABRLD2017-02-09
N208684-002EMFLAZADEFLAZACORT18MGTABLET / ORALABRLD2017-02-09
N208684-003EMFLAZADEFLAZACORT30MGTABLET / ORALABRLD2017-02-09
N208684-004EMFLAZADEFLAZACORT36MGTABLET / ORALABRLD, RS2017-02-09

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 4 matching rows.

Application-product, TE code table
Application-productTE code
N208684-001AB
N208684-002AB
N208684-003AB
N208684-004AB

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 4 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N208684-001ODE-2522026-06-07
N208684-002ODE-2522026-06-07
N208684-003ODE-2522026-06-07
N208684-004ODE-2522026-06-07

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 5 · 164 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N208684-001EMFLAZA6MGTABLET / ORALABRLD2017-02-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208684-002EMFLAZA18MGTABLET / ORALABRLD2017-02-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208684-003EMFLAZA30MGTABLET / ORALABRLD2017-02-09011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208684-004EMFLAZA36MGTABLET / ORALABRLD, RS2017-02-09011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208684-001EMFLAZA6MGTABLET / ORALABRLD2017-02-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208684-002EMFLAZA18MGTABLET / ORALABRLD2017-02-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208684-003EMFLAZA30MGTABLET / ORALABRLD2017-02-0931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208684-004EMFLAZA36MGTABLET / ORALABRLD, RS2017-02-0931067a03dcf5…
2025-08-23 18:47 UTC2025-08N208684-001EMFLAZA6MGTABLET / ORALABRLD2017-02-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208684-002EMFLAZA18MGTABLET / ORALABRLD2017-02-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208684-003EMFLAZA30MGTABLET / ORALABRLD2017-02-096a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208684-004EMFLAZA36MGTABLET / ORALABRLD, RS2017-02-096a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208684-001EMFLAZA6MGTABLET / ORALABRLD2017-02-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208684-002EMFLAZA18MGTABLET / ORALABRLD2017-02-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208684-003EMFLAZA30MGTABLET / ORALABRLD2017-02-09fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208684-004EMFLAZA36MGTABLET / ORALABRLD, RS2017-02-09fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208684-001EMFLAZA6MGTABLET / ORALABRLD2017-02-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208684-002EMFLAZA18MGTABLET / ORALABRLD2017-02-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208684-003EMFLAZA30MGTABLET / ORALABRLD2017-02-09b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208684-004EMFLAZA36MGTABLET / ORALABRLD, RS2017-02-09b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-001EMFLAZA6MGTABLET / ORALABRLD2017-02-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-002EMFLAZA18MGTABLET / ORALABRLD2017-02-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-003EMFLAZA30MGTABLET / ORALABRLD2017-02-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-004EMFLAZA36MGTABLET / ORALABRLD, RS2017-02-0903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-001EMFLAZA6MGTABLET / ORALABRLD2017-02-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-002EMFLAZA18MGTABLET / ORALABRLD2017-02-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-003EMFLAZA30MGTABLET / ORALABRLD2017-02-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-004EMFLAZA36MGTABLET / ORALABRLD, RS2017-02-092680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208684-001EMFLAZA6MGTABLET / ORALABRLD2017-02-095bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208684-002EMFLAZA18MGTABLET / ORALABRLD2017-02-095bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208684-003EMFLAZA30MGTABLET / ORALABRLD2017-02-095bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208684-004EMFLAZA36MGTABLET / ORALABRLD, RS2017-02-095bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208684-001EMFLAZA6MGTABLET / ORALABRLD2017-02-09d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208684-002EMFLAZA18MGTABLET / ORALABRLD2017-02-09d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208684-003EMFLAZA30MGTABLET / ORALABRLD2017-02-09d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208684-004EMFLAZA36MGTABLET / ORALABRLD, RS2017-02-09d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N208684-001EMFLAZA6MGTABLET / ORALABRLD2017-02-09d06236e962d9…
2024-10-29 15:01 UTC2024-10N208684-002EMFLAZA18MGTABLET / ORALABRLD2017-02-09d06236e962d9…
2024-10-29 15:01 UTC2024-10N208684-003EMFLAZA30MGTABLET / ORALABRLD2017-02-09d06236e962d9…
2024-10-29 15:01 UTC2024-10N208684-004EMFLAZA36MGTABLET / ORALABRLD, RS2017-02-09d06236e962d9…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 64 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02N208684-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208684-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208684-003AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208684-004AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208684-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208684-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208684-003AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208684-004AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N208684-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208684-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208684-003AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208684-004AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208684-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208684-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208684-003AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208684-004AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208684-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208684-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208684-003AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208684-004AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-003AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-004AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-003AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-004AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208684-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208684-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208684-003AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208684-004AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208684-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208684-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208684-003AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208684-004AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N208684-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N208684-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N208684-003AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N208684-004AB1d06236e962d9…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 10 · 368 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-02-19 14:30 UTC2026-02N208684-001ODE-2522026-06-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208684-002ODE-2522026-06-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208684-003ODE-2522026-06-07011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208684-004ODE-2522026-06-07011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208684-001ODE-2522026-06-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208684-002ODE-2522026-06-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208684-003ODE-2522026-06-0731067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208684-004ODE-2522026-06-0731067a03dcf5…
2025-08-23 18:47 UTC2025-08N208684-001ODE-2522026-06-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208684-002ODE-2522026-06-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208684-003ODE-2522026-06-076a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208684-004ODE-2522026-06-076a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208684-001ODE-2522026-06-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208684-002ODE-2522026-06-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208684-003ODE-2522026-06-07fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208684-004ODE-2522026-06-07fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208684-001ODE-2522026-06-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208684-002ODE-2522026-06-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208684-003ODE-2522026-06-07b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208684-004ODE-2522026-06-07b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-001ODE-1302024-02-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-001ODE-2522026-06-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-002ODE-1302024-02-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-002ODE-2522026-06-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-003ODE-1302024-02-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-003ODE-2522026-06-0703ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-004ODE-1302024-02-0903ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208684-004ODE-2522026-06-0703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-001ODE-1302024-02-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-001ODE-2522026-06-072680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-002ODE-1302024-02-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-002ODE-2522026-06-072680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-003ODE-1302024-02-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-003ODE-2522026-06-072680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-004ODE-1302024-02-092680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208684-004ODE-2522026-06-072680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208684-001ODE-1302024-02-095bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208684-001ODE-2522026-06-075bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208684-002ODE-1302024-02-095bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208684-002ODE-2522026-06-075bbf6a4d5a75…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
EMFLAZADEFLAZACORTPTC Therapeutics, Inc.31b347d2-f156-4055-9d8f-7cf0df4202962025-11-13Warnings, Adverse reactionsExact identifier
application applno (NDA): 208684
application number: NDA208684
ndc (product): 52856-502
ndc (product): 52856-504
ndc (product): 52856-503
ndc (product): 52856-501

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 44 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
42998-501EMFLAZAdeflazacortMarathon Pharmaceuticals, LLCNDACurrent
42998-501EMFLAZAdeflazacortMarathon Pharmaceuticals, LLCNDACurrent
42998-502EMFLAZAdeflazacortMarathon Pharmaceuticals, LLCNDACurrent
42998-502EMFLAZAdeflazacortMarathon Pharmaceuticals, LLCNDACurrent
42998-503EMFLAZAdeflazacortMarathon Pharmaceuticals, LLCNDACurrent
42998-503EMFLAZAdeflazacortMarathon Pharmaceuticals, LLCNDACurrent
42998-504EMFLAZAdeflazacortMarathon Pharmaceuticals, LLCNDACurrent
42998-504EMFLAZAdeflazacortMarathon Pharmaceuticals, LLCNDACurrent
52856-501EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-501EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-501EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-501EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-501EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-501EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-501EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-501EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-501EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-502EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-502EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-502EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-502EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-502EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-502EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-502EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-502EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-502EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-503EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-503EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-503EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-503EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-503EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-503EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-503EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-503EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-503EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-504EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-504EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-504EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-504EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-504EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-504EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-504EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-504EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent
52856-504EMFLAZAdeflazacortPTC Therapeutics, Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
78739SUPPL 2024-07-02
78663SUPPL 2024-06-06
70085SUPPL2022-02-04
67978SUPPL2021-06-30
63950SUPPL2020-07-17
63890SUPPL2020-07-14
59009SUPPL2019-06-11
58996SUPPL2019-06-07
47511ORIG2017-03-09
47143ORIG2017-02-09
47140ORIG2017-02-09