Application 208745

Type
NDA
Sponsor
SALIX

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001TRULANCEPLECANATIDETABLET;ORAL3MGYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N208745-001TRULANCEPLECANATIDE3MGTABLET / ORALRLD, RS2017-01-19

Orange Book patents#

Current patent rows page 1 of 1 · 12 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N208745-00170417862028-01-30Drug substance2017-02-14
N208745-00196103212031-09-15U-19992017-05-01
N208745-00196103212031-09-15U-22302017-05-01
N208745-00199190242031-09-15U-19992018-04-10
N208745-00199190242031-09-15U-22302018-04-10
N208745-00199252312031-09-15Drug product2018-04-10
N208745-001113193462032-03-01Drug product2022-05-11
N208745-00196160972032-08-20Drug product2017-05-01
N208745-001100116372034-06-05Drug substance2018-07-19
N208745-001111425492034-06-05Drug product2021-10-25
N208745-001118345212034-06-05Drug product2023-12-14
N208745-001121460032034-06-05Drug product2024-11-25

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-1931067a03dcf5…
2025-08-23 18:47 UTC2025-08N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-196a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-1903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-192680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-195bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-1979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-191e350fbaab3a…
2024-05-31 18:47 UTC2024-05N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-198072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-195c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-195d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-194b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-1974a2ff9319b5…
2022-03-09 01:35 UTC2022-03N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-1987673890dc5c…
2021-03-12 10:30 UTC2021-03N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-195aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-198869cabd3fbd…
2020-11-12 02:37 UTC2020-11N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19c0c555d07b60…
2019-12-14 00:12 UTC2019-12N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-193f01610625f2…
2019-09-15 20:21 UTC2019-09N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19b00525d2431f…
2019-07-19 19:46 UTC2019-07N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-196a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-191c564ffb4f44…
2023-12-20 04:57 UTC2023-12N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-199b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-193f0d92c62455…
2023-05-13 08:27 UTC2023-05N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19053a50430f4f…
2023-01-26 05:58 UTC2023-01N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-193bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-193a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N208745-001TRULANCE3MGTABLET / ORALRLD, RS2017-01-19cb3db0bc1861…

Observed Orange Book patent history#

Patent history page 1 of 12 · 451 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-02-19 14:30 UTC2026-02N208745-00170417862028-01-30Drug substance2017-02-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208745-00196103212031-09-15U-19992017-05-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208745-00196103212031-09-15U-22302017-05-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208745-00199190242031-09-15U-22302018-04-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208745-00199190242031-09-15U-19992018-04-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208745-00199252312031-09-15Drug product2018-04-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208745-001113193462032-03-01Drug product2022-05-11011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208745-00196160972032-08-20Drug product2017-05-01011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208745-001100116372034-06-05Drug substance2018-07-19011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208745-001111425492034-06-05Drug product2021-10-25011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208745-001118345212034-06-05Drug product2023-12-14011fe1cb6892…
2026-02-19 14:30 UTC2026-02N208745-001121460032034-06-05Drug product2024-11-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208745-00170417862028-01-30Drug substance2017-02-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208745-00196103212031-09-15U-19992017-05-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208745-00196103212031-09-15U-22302017-05-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208745-00199190242031-09-15U-22302018-04-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208745-00199190242031-09-15U-19992018-04-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208745-00199252312031-09-15Drug product2018-04-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208745-001113193462032-03-01Drug product2022-05-1131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208745-00196160972032-08-20Drug product2017-05-0131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208745-001100116372034-06-05Drug substance2018-07-1931067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208745-001111425492034-06-05Drug product2021-10-2531067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208745-001118345212034-06-05Drug product2023-12-1431067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N208745-001121460032034-06-05Drug product2024-11-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08N208745-00170417862028-01-30Drug substance2017-02-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208745-00196103212031-09-15U-19992017-05-016a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208745-00196103212031-09-15U-22302017-05-016a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208745-00199190242031-09-15U-22302018-04-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208745-00199190242031-09-15U-19992018-04-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208745-00199252312031-09-15Drug product2018-04-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208745-001113193462032-03-01Drug product2022-05-116a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208745-00196160972032-08-20Drug product2017-05-016a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208745-001100116372034-06-05Drug substance2018-07-196a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208745-001111425492034-06-05Drug product2021-10-256a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208745-001118345212034-06-05Drug product2023-12-146a471c1ec25d…
2025-08-23 18:47 UTC2025-08N208745-001121460032034-06-05Drug product2024-11-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208745-00170417862028-01-30Drug substance2017-02-14fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208745-00196103212031-09-15U-19992017-05-01fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208745-00196103212031-09-15U-22302017-05-01fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N208745-00199190242031-09-15U-22302018-04-10fd3edfee7708…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N208745-001NCE2022-01-195c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N208745-001NCE2022-01-195d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N208745-001NCE2022-01-194b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N208745-001I-7642021-01-2474a2ff9319b5…
2019-12-13 00:20 UTC2019-12N208745-001NCE2022-01-1974a2ff9319b5…
2022-03-09 01:35 UTC2022-03N208745-001NCE2022-01-19bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N208745-001I-7642021-01-24782e0a99824c…
2021-12-28 21:50 UTC2021-12N208745-001NCE2022-01-19782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N208745-001I-7642021-01-2487673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N208745-001NCE2022-01-1987673890dc5c…
2021-03-12 10:30 UTC2021-03N208745-001I-7642021-01-245aa47cf7b7d7…
2021-03-12 10:30 UTC2021-03N208745-001NCE2022-01-195aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N208745-001I-7642021-01-248869cabd3fbd…
2020-12-22 03:56 UTC2020-12N208745-001NCE2022-01-198869cabd3fbd…
2020-11-12 02:37 UTC2020-11N208745-001I-7642021-01-24c0c555d07b60…
2020-11-12 02:37 UTC2020-11N208745-001NCE2022-01-19c0c555d07b60…
2019-12-14 00:12 UTC2019-12N208745-001I-7642021-01-243f01610625f2…
2019-12-14 00:12 UTC2019-12N208745-001NCE2022-01-193f01610625f2…
2019-09-15 20:21 UTC2019-09N208745-001I-7642021-01-24b00525d2431f…
2019-09-15 20:21 UTC2019-09N208745-001NCE2022-01-19b00525d2431f…
2019-07-19 19:46 UTC2019-07N208745-001I-7642021-01-24ea99ee380514…
2019-07-19 19:46 UTC2019-07N208745-001NCE2022-01-19ea99ee380514…
2023-01-26 05:58 UTC2023-01N208745-001NCE2022-01-193bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N208745-001NCE2022-01-193a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N208745-001NCE2022-01-19f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N208745-001NCE2022-01-19e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N208745-001NCE2022-01-19cb3db0bc1861…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Trulance Immediate releasePLECANATIDESalix Pharmaceuticals Inc.fe2895bf-71a6-493a-b0ca-e06b2dfefc822024-04-04Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 208745
application number: NDA208745
ndc (product): 65649-003

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 13 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
65649-003TrulancePlecanatideSalix Pharmaceuticals Inc.NDACurrent
65649-003TrulancePlecanatideSalix Pharmaceuticals Inc.NDACurrent
65649-003TrulancePlecanatideSalix PharmaceuticalsNDACurrent
65649-003TrulancePlecanatideSalix Pharmaceuticals Inc.NDACurrent
65649-003TrulancePlecanatideSalix Pharmaceuticals Inc.NDACurrent
65649-003TrulancePlecanatideSalix Pharmaceuticals Inc.NDACurrent
65649-003TrulancePlecanatideSalix PharmaceuticalsNDACurrent
65649-003TrulancePlecanatideSalix Pharmaceuticals Inc.NDACurrent
65649-003TrulancePlecanatideSalix Pharmaceuticals Inc.NDACurrent
65649-003TrulancePlecanatideSalix PharmaceuticalsNDACurrent
70194-003TrulancePlecanatideSynergy Pharmaceuticals Inc.NDACurrent
70194-003TrulancePlecanatideSynergy Pharmaceuticals Inc.NDACurrent
70194-003TrulancePlecanatideSynergy Pharmaceuticals Inc.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
67083SUPPL2021-04-16
67082SUPPL2021-04-16
67054SUPPL2021-04-14
66247SUPPL2021-02-17
66246SUPPL2021-02-17
66196SUPPL2021-02-11
65556SUPPL2020-12-10
65119SUPPL2020-11-02
65079SUPPL2020-10-30
65078SUPPL2020-10-30
65077SUPPL2020-10-30
65073SUPPL2020-10-29
55016SUPPL2018-07-26
52106SUPPL2018-01-30
51919SUPPL2018-01-26
51918SUPPL2018-01-24
47466ORIG2017-03-03
46927ORIG2017-01-23
46926ORIG2017-01-23