Application 213138

Type
NDA
Sponsor
CUBIST PHARMS LLC

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001DIFICIDFIDAXOMICINFOR SUSPENSION;ORAL40MG/MLYesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N213138-001DIFICIDFIDAXOMICIN40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24

Orange Book patents#

Current patent rows page 1 of 1 · 10 matching rows.

Application-product, Patent, Expiration table
Application-productPatentExpirationUse codeCoverage / statusSubmission date
N213138-00179064892027-03-04U-27412020-02-21
N213138-00173785082027-07-31Drug substance, Drug product2020-02-21
N213138-00178632492027-07-31Drug product2020-02-21
N213138-00188595102027-07-31U-27412020-02-21
N213138-0017906489*PED2027-09-04Pediatric extension
N213138-0017378508*PED2028-01-31Pediatric extension
N213138-0017863249*PED2028-01-31Pediatric extension
N213138-0018859510*PED2028-01-31Pediatric extension
N213138-00198085302034-05-28Drug product2020-02-21
N213138-0019808530*PED2034-11-28Pediatric extension

Orange Book exclusivity#

Current exclusivity rows page 1 of 1 · 1 matching rows.

Application-product, Exclusivity code, Expiration table
Application-productExclusivity codeExpiration
N213138-001ODE-3672027-01-24

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-09-14 22:38:342026-08N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-2484e616aacf4f…
2026-08-18 06:07:402026-07N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-2403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-242680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-245bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-2479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-241e350fbaab3a…
2024-05-31 18:47 UTC2024-05N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-248072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-245c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-245d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-244b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-2487673890dc5c…
2021-03-12 10:30 UTC2021-03N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-245aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-248869cabd3fbd…
2020-11-12 02:37 UTC2020-11N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24c0c555d07b60…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-246a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-241c564ffb4f44…
2023-12-20 04:57 UTC2023-12N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-249b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-243f0d92c62455…
2023-05-13 08:27 UTC2023-05N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24053a50430f4f…
2023-01-26 05:58 UTC2023-01N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-243bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-243a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06N213138-001DIFICID40MG/MLFOR SUSPENSION / ORALRLD, RS2020-01-24a50c72e98297…

Observed Orange Book patent history#

Patent history page 1 of 12 · 441 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productPatentExpirationUse codeCoverage / statusSubmission dateSource SHA-256
2026-09-14 22:38:342026-08N213138-00179064892027-03-04U-27412020-02-2184e616aacf4f…
2026-09-14 22:38:342026-08N213138-00173785082027-07-31Drug substance, Drug product2020-02-2184e616aacf4f…
2026-09-14 22:38:342026-08N213138-00178632492027-07-31Drug product2020-02-2184e616aacf4f…
2026-09-14 22:38:342026-08N213138-00188595102027-07-31U-27412020-02-2184e616aacf4f…
2026-09-14 22:38:342026-08N213138-0017906489*PED2027-09-04Pediatric extension84e616aacf4f…
2026-09-14 22:38:342026-08N213138-0017378508*PED2028-01-31Pediatric extension84e616aacf4f…
2026-09-14 22:38:342026-08N213138-0017863249*PED2028-01-31Pediatric extension84e616aacf4f…
2026-09-14 22:38:342026-08N213138-0018859510*PED2028-01-31Pediatric extension84e616aacf4f…
2026-09-14 22:38:342026-08N213138-00198085302034-05-28Drug product2020-02-2184e616aacf4f…
2026-09-14 22:38:342026-08N213138-0019808530*PED2034-11-28Pediatric extension84e616aacf4f…
2026-08-18 06:07:402026-07N213138-00179064892027-03-04U-27412020-02-21caaa826d4ba7…
2026-08-18 06:07:402026-07N213138-00173785082027-07-31Drug substance, Drug product2020-02-21caaa826d4ba7…
2026-08-18 06:07:402026-07N213138-00178632492027-07-31Drug product2020-02-21caaa826d4ba7…
2026-08-18 06:07:402026-07N213138-00188595102027-07-31U-27412020-02-21caaa826d4ba7…
2026-08-18 06:07:402026-07N213138-0017906489*PED2027-09-04Pediatric extensioncaaa826d4ba7…
2026-08-18 06:07:402026-07N213138-0017378508*PED2028-01-31Pediatric extensioncaaa826d4ba7…
2026-08-18 06:07:402026-07N213138-0017863249*PED2028-01-31Pediatric extensioncaaa826d4ba7…
2026-08-18 06:07:402026-07N213138-0018859510*PED2028-01-31Pediatric extensioncaaa826d4ba7…
2026-08-18 06:07:402026-07N213138-00198085302034-05-28Drug product2020-02-21caaa826d4ba7…
2026-08-18 06:07:402026-07N213138-0019808530*PED2034-11-28Pediatric extensioncaaa826d4ba7…
2026-02-19 14:30 UTC2026-02N213138-00179064892027-03-04U-27412020-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213138-00173785082027-07-31Drug substance, Drug product2020-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213138-00178632492027-07-31Drug product2020-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213138-00188595102027-07-31U-27412020-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213138-0017906489*PED2027-09-04Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213138-0017378508*PED2028-01-31Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213138-0017863249*PED2028-01-31Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213138-0018859510*PED2028-01-31Pediatric extension011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213138-00198085302034-05-28Drug product2020-02-21011fe1cb6892…
2026-02-19 14:30 UTC2026-02N213138-0019808530*PED2034-11-28Pediatric extension011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213138-00179064892027-03-04U-27412020-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213138-00173785082027-07-31Drug substance, Drug product2020-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213138-00178632492027-07-31Drug product2020-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213138-00188595102027-07-31U-27412020-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213138-0017906489*PED2027-09-04Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213138-0017378508*PED2028-01-31Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213138-0017863249*PED2028-01-31Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213138-0018859510*PED2028-01-31Pediatric extension31067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213138-00198085302034-05-28Drug product2020-02-2131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213138-0019808530*PED2034-11-28Pediatric extension31067a03dcf5…

Observed Orange Book exclusivity history#

Exclusivity history page 1 of 2 · 74 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2026-09-14 22:38:342026-08N213138-001ODE-3672027-01-2484e616aacf4f…
2026-08-18 06:07:402026-07N213138-001ODE-3672027-01-24caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N213138-001ODE-3672027-01-24011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N213138-001ODE-3672027-01-2431067a03dcf5…
2025-08-23 18:47 UTC2025-08N213138-001ODE-3672027-01-246a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N213138-001ODE-3672027-01-24fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N213138-001ODE-3672027-01-24b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N213138-001ODE-3672027-01-2403ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N213138-001ODE-3672027-01-242680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N213138-001ODE-3672027-01-245bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N213138-001ODE-3672027-01-24d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N213138-001ODE-3672027-01-24d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N213138-001ODE-3672027-01-2479d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N213138-001ODE-3672027-01-24301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N213138-001ODE-3672027-01-241e350fbaab3a…
2024-05-31 18:47 UTC2024-05N213138-001ODE-3672027-01-248072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N213138-001NP2023-01-245c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N213138-001PED2023-07-245c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N213138-001ODE-3672027-01-245c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N213138-001NP2023-01-245d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N213138-001PED2023-07-245d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N213138-001ODE-3672027-01-245d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N213138-001NP2023-01-244b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N213138-001PED2023-07-244b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N213138-001ODE-3672027-01-244b0b4de00fa7…
2022-03-09 01:35 UTC2022-03N213138-001NP2023-01-24bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N213138-001PED2023-07-24bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N213138-001ODE-3672027-01-24bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N213138-001NP2023-01-24782e0a99824c…
2021-12-28 21:50 UTC2021-12N213138-001PED2023-07-24782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N213138-001NP2023-01-2487673890dc5c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N213138-001PED2023-07-2487673890dc5c…
2021-03-12 10:30 UTC2021-03N213138-001NP2023-01-245aa47cf7b7d7…
2021-03-12 10:30 UTC2021-03N213138-001PED2023-07-245aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N213138-001NP2023-01-248869cabd3fbd…
2020-12-22 03:56 UTC2020-12N213138-001PED2023-07-248869cabd3fbd…
2020-11-12 02:37 UTC2020-11N213138-001NP2023-01-24c0c555d07b60…
2020-11-12 02:37 UTC2020-11N213138-001PED2023-07-24c0c555d07b60…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N213138-001ODE-3672027-01-246a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N213138-001ODE-3672027-01-241c564ffb4f44…

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
DificidFIDAXOMICINMerck Sharp & Dohme LLCdd966338-c820-4270-b704-09ef75fa3ceb2024-10-16Warnings, Adverse reactionsExact identifier
application applno (NDA): 213138
application number: NDA213138
ndc (product): 52015-700

NDC Listings For This Application#

NDC listings for this application page 1 of 1 · 6 matching rows.

NDC, Name, Nonproprietary name table
NDCNameNonproprietary nameLabelerMarketing categoryStatus
52015-700DIFICIDFIDAXOMICINMerck Sharp & Dohme Corp.NDACurrent
52015-700DIFICIDFIDAXOMICINMerck Sharp & Dohme Corp.NDACurrent
52015-700DIFICIDFIDAXOMICINMerck Sharp & Dohme LLCNDACurrent
52015-700DIFICIDFIDAXOMICINMerck Sharp & Dohme LLCNDACurrent
52015-700DIFICIDFIDAXOMICINMerck Sharp & Dohme Corp.NDACurrent
52015-700DIFICIDFIDAXOMICINMerck Sharp & Dohme Corp.NDACurrent

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
63569ORIG2020-06-15
63361SUPPL2020-06-01
63348SUPPL2020-05-29
61697ORIG2020-01-27
61695ORIG2020-01-27
62998ORIG1900-01-01