Application 218475

Type
NDA
Sponsor
BAXTER HLTHCARE CORP

Application Products#

Product, Drug, Ingredient table
ProductDrugIngredientFormStrengthReference drugReference standard
001EPINEPHRINE BITARTRATE IN 0.9% SODIUM CHLORIDEEPINEPHRINE BITARTRATESOLUTION;INTRAVENOUSEQ 16MG BASE/250ML (EQ 64MCG BASE/ML)YesYes
002EPINEPHRINE BITARTRATE IN 0.9% SODIUM CHLORIDEEPINEPHRINE BITARTRATESOLUTION;INTRAVENOUSEQ 4MG BASE/250ML (EQ 16MCG BASE/ML)YesYes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N218475-001EPINEPHRINE BITARTRATE IN 0.9% SODIUM CHLORIDEEPINEPHRINE BITARTRATEEQ 16MG BASE/250ML (EQ 64MCG BASE/ML)SOLUTION / INTRAVENOUSRLD2025-02-28
N218475-002EPINEPHRINE BITARTRATE IN 0.9% SODIUM CHLORIDEEPINEPHRINE BITARTRATEEQ 4MG BASE/250ML (EQ 16MCG BASE/ML)SOLUTION / INTRAVENOUSRLD, RS2026-03-16

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-01 22:54:322026-06N218475-001EPINEPHRINE BITARTRATE IN 0.9% SODIUM CHLORIDEEQ 16MG BASE/250ML (EQ 64MCG BASE/ML)SOLUTION / INTRAVENOUSRLD2025-02-28a50c72e98297…
2026-08-01 22:54:322026-06N218475-002EPINEPHRINE BITARTRATE IN 0.9% SODIUM CHLORIDEEQ 4MG BASE/250ML (EQ 16MCG BASE/ML)SOLUTION / INTRAVENOUSRLD, RS2026-03-16a50c72e98297…

openFDA label cross-check#

Cross-check layer: openFDA label JSON enriches search and identifies hydration gaps. The DailyMed Structured Product Label remains the canonical label presentation on FDA.report. Every label matching the complete exact-identifier union is deduplicated and paginated below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
epinephrineEPINEPHRINEBaxter Healthcare Corporation60efd409-3555-4182-a68d-1cd7bc0d1bfc2026-03-16Warnings, Adverse reactionsExact identifier
application applno (NDA): 218475
application number: NDA218475

Documents#

Document, Submission type, Date table
DocumentSubmission typeDate
83642SUPPL 2025-10-03
81429ORIG 2025-03-04
81393ORIG 2025-03-03