ProBLEN Estrogen and Progesterone
- Manufacturer
- Liddell Laboratories, Inc.
- Effective date
- 2012-02-06
- Label type
- HUMAN OTC DRUG LABEL
- Version
- 1
- Source
- full-release
- Hydrated at
- 2026-06-01 02:03:32
Label at a glance#
ProductProBLEN Estrogen and Progesterone
Active ingredientCHASTE TREE, ANGELICA SINENSIS ROOT, APIS MELLIFERA, ARNICA MONTANA, BLACK COHOSH, ESTRADIOL, ESTRIOL, ESTRONE, GALIUM APARINE, GLYCYRRHIZA GLABRA, ASIAN GINSENG, PROGESTERONE, SEPIA OFFICINALIS JUICE, THUJA OCCIDENTALIS LEAFY TWIG, VISCUM ALBUM FRUITING TOP, BOS TAURUS OVARY
Label structure9 sections
Contacts and useful links#
Websitewww.problen.com
www.problen.com
www.problen.comLabel contents#
Full prescribing information#
OTC - ACTIVE INGREDIENT SECTION
ACTIVE INGREDIENTS: Agnus castus 3X, Angelica sinensis, radix 3X, Apis mellifica 6X, Arnica montana 6X, Cimicifuga racemosa 3X, Estradiol 9C, Estriol 9C, Folliculinum 9C, Galium aparine 3X, Glycyrrhiza glabra 3X, Korean ginseng 3X, Oophorinum bovinum 30C, Progesterone 6X, Sepia 30C, Thuja occidentalis 6X, Viscum album 3X.
OTC - PURPOSE SECTION
INDICATIONS: Temporarily supports the body to rebalance estrogen output. Symptoms may include: mood swings, hot flashes, irritability, lack of energy.
WARNINGS SECTION
WARNINGS: Not for use on children. If symptoms continue to recur, or if sleeplessness persists continuously for more than two weeks, consult a physician. Insomnia may be a symptom of a serious underlying medical illness.
As with all medicines, if you are pregnant or breast feeding, consult a health professional before using this product.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
TAMPER EVIDENT: There is a seal around the neck of the bottle. Do not use if this seal is broken or missing.
DOSAGE & ADMINISTRATION SECTION
DIRECTIONS: Adults: Hold the spray-top close to your open mouth and spray twice directly under your tongue, three times a day. Some people notice improvement within two or three weeks, others take longer.
INACTIVE INGREDIENT SECTION
INACTIVE INGREDIENTS: Organic alcohol 30% v/v, Purified water.
OTC - KEEP OUT OF REACH OF CHILDREN SECTION
KEEP OUT OF REACH OF CHILDREN. In case of overdose, get medical help or contact a Poison Control Center right away.
INDICATIONS & USAGE SECTION
INDICATIONS: Temporarily supports the body to rebalance estrogen output. Symptoms may include: mood swings, hot flashes, irritability, lack of energy.
OTC - QUESTIONS SECTION
PACKAGE LABEL.PRINCIPAL DISPLAY PANEL
Estrogen and Progesterone
HOMEOPATHIC
ORGANOTHERAPY
1.0 FL OZ (30 ML)
DailyMed Product Concepts#
FDA-Initiated Inactive NDC Indexing#
| NDC | Effective | Action | Document | Indexing SPL | Related label |
|---|---|---|---|---|---|
| 50845-0138-3 | 2019-11-13 | C162847 | 48780-1 | 97449f38-d50e-f6ea-e053-dbdaa90aa703 | ProBLEN Estrogen & Progesterone |
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 50845-0138-1 | ProBLEN Estrogen and Progesterone | 30 mL in 1 BOTTLE, SPRAY | SPRAY | 30 | 1 | |
| 50845-0138-2 | ProBLEN Estrogen and Progesterone | 1 in 1 CARTON | SPRAY | 1 | 1 | |
| 50845-0138-3 | ProBLEN Estrogen and Progesterone | 1 in 1 CARTON | SPRAY | 1 | 1 |
DailyMed Dashboard NDC Coverage#
| NDC | Dashboard title | SPL version | Validation | Dashboard ZIP |
|---|---|---|---|---|
| 50845-0138 | PROBLEN ESTROGEN AND PROGESTERONE (AGNUS CASTUS, ANGELICA SINESIS, RADIX, APIS MELLIFICA, ARNICA MONTANA, CIMICIFUGA RACEMOSA, ESTRADIOL, ESTRIOL, FOLLICULINUM, GALIUM APARINE,) SPRAY [LIDDELL LABORATORIES, INC.] | 1 | Legacy NDC, 3 package rows | 20120207_05ab659e-c5de-4492-8b76-58be39aa1f76.zip |
DailyMed Socrata Ingredients#
| Ingredient | Type | UNII | SPL version | Uploaded |
|---|---|---|---|---|
| ANGELICA SINENSIS ROOT | ACTIVE INGREDIENT | B66F4574UG | 1 | |
| APIS MELLIFERA | ACTIVE INGREDIENT | 7S82P3R43Z | 1 | |
| ARNICA MONTANA | ACTIVE INGREDIENT | O80TY208ZW | 1 | |
| ASIAN GINSENG | ACTIVE INGREDIENT | CUQ3A77YXI | 1 | |
| BLACK COHOSH | ACTIVE INGREDIENT | K73E24S6X9 | 1 | |
| BOS TAURUS OVARY | ACTIVE INGREDIENT | 66LZN1C747 | 1 | |
| CHASTE TREE | ACTIVE INGREDIENT | 433OSF3U8A | 1 | |
| ESTRADIOL | ACTIVE INGREDIENT | 4TI98Z838E | 1 | |
| ESTRIOL | ACTIVE INGREDIENT | FB33469R8E | 1 | |
| ESTRONE | ACTIVE INGREDIENT | 2DI9HA706A | 1 | |
| GALIUM APARINE | ACTIVE INGREDIENT | Z4B6561488 | 1 | |
| GLYCYRRHIZA GLABRA | ACTIVE INGREDIENT | 2788Z9758H | 1 | |
| PROGESTERONE | ACTIVE INGREDIENT | 4G7DS2Q64Y | 1 | |
| SEPIA OFFICINALIS JUICE | ACTIVE INGREDIENT | QDL83WN8C2 | 1 | |
| THUJA OCCIDENTALIS LEAFY TWIG | ACTIVE INGREDIENT | 1NT28V9397 | 1 | |
| VISCUM ALBUM FRUITING TOP | ACTIVE INGREDIENT | BK9092J5MP | 1 | |
| ANGELICA SINENSIS ROOT | ACTIVE MOIETY | B66F4574UG | 1 | |
| APIS MELLIFERA | ACTIVE MOIETY | 7S82P3R43Z | 1 | |
| ARNICA MONTANA | ACTIVE MOIETY | O80TY208ZW | 1 | |
| ASIAN GINSENG | ACTIVE MOIETY | CUQ3A77YXI | 1 | |
| BLACK COHOSH | ACTIVE MOIETY | K73E24S6X9 | 1 | |
| BOS TAURUS OVARY | ACTIVE MOIETY | 66LZN1C747 | 1 | |
| CHASTE TREE | ACTIVE MOIETY | 433OSF3U8A | 1 | |
| ESTRADIOL | ACTIVE MOIETY | 4TI98Z838E | 1 | |
| ESTRIOL | ACTIVE MOIETY | FB33469R8E | 1 | |
| ESTRONE | ACTIVE MOIETY | 2DI9HA706A | 1 | |
| GALIUM APARINE | ACTIVE MOIETY | Z4B6561488 | 1 | |
| GLYCYRRHIZA GLABRA | ACTIVE MOIETY | 2788Z9758H | 1 | |
| PROGESTERONE | ACTIVE MOIETY | 4G7DS2Q64Y | 1 | |
| SEPIA OFFICINALIS JUICE | ACTIVE MOIETY | QDL83WN8C2 | 1 | |
| THUJA OCCIDENTALIS LEAFY TWIG | ACTIVE MOIETY | 1NT28V9397 | 1 | |
| VISCUM ALBUM FRUITING TOP | ACTIVE MOIETY | BK9092J5MP | 1 | |
| ALCOHOL | INACTIVE INGREDIENT | 3K9958V90M | 1 | |
| WATER | INACTIVE INGREDIENT | 059QF0KO0R | 1 |
Products#
Every source-derived product name is available through these pages.
- ProBLEN Estrogen and Progesterone
- Agnus castus, Angelica sinesis, radix, Apis mellifica, Arnica montana, Cimicifuga racemosa, Estradiol, Estriol, Folliculinum, Galium aparine,
- CHASTE TREE
- ANGELICA SINENSIS ROOT
- APIS MELLIFERA
- ARNICA MONTANA
- BLACK COHOSH
- ESTRADIOL
- ESTRIOL
- ESTRONE
- GALIUM APARINE
- GLYCYRRHIZA GLABRA
- ASIAN GINSENG
- PROGESTERONE
- SEPIA OFFICINALIS JUICE
- THUJA OCCIDENTALIS LEAFY TWIG
- VISCUM ALBUM FRUITING TOP
- WATER
- ALCOHOL
- BOS TAURUS OVARY
NDC Codes#
| Product NDC | Package NDC |
|---|---|
| 50845-0138 | 50845-0138-1, 50845-0138-2, 50845-0138-3 |
Ingredients#
Every source-derived ingredient row is available through these pages.
| Name | UNII | Kind |
|---|---|---|
| CHASTE TREE | 433OSF3U8A | ACTIB |
| ANGELICA SINENSIS ROOT | B66F4574UG | ACTIB |
| APIS MELLIFERA | 7S82P3R43Z | ACTIB |
| ARNICA MONTANA | O80TY208ZW | ACTIB |
| BLACK COHOSH | K73E24S6X9 | ACTIB |
| ESTRADIOL | 4TI98Z838E | ACTIB |
| ESTRIOL | FB33469R8E | ACTIB |
| ESTRONE | 2DI9HA706A | ACTIB |
| GALIUM APARINE | Z4B6561488 | ACTIB |
| GLYCYRRHIZA GLABRA | 2788Z9758H | ACTIB |
| ASIAN GINSENG | CUQ3A77YXI | ACTIB |
| PROGESTERONE | 4G7DS2Q64Y | ACTIB |
| SEPIA OFFICINALIS JUICE | QDL83WN8C2 | ACTIB |
| THUJA OCCIDENTALIS LEAFY TWIG | 1NT28V9397 | ACTIB |
| VISCUM ALBUM FRUITING TOP | BK9092J5MP | ACTIB |
| WATER | 059QF0KO0R | IACT |
| ALCOHOL | 3K9958V90M | IACT |
| BOS TAURUS OVARY | 66LZN1C747 | ACTIB |
Source Document#
Inactive ingredient matches#
Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.
| DailyMed ingredient | IID ingredient | UNII | Dosage form / route | Potency | Maximum daily exposure | Match |
|---|---|---|---|---|---|---|
| ALCOHOL | ALCOHOL | 3K9958V90M | LIQUID / INTRAMUSCULAR | 400 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | GEL / TRANSDERMAL | 7360 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | MOUTHWASH / BUCCAL | 200 mg/1ml | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | LIQUID / INTRAVENOUS | 400 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | DROPS / NASAL | 10 mg/1ml | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SOLUTION / OPHTHALMIC | 0.5 %w/v | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | INJECTION / INTRAVENOUS | 92 %w/v | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | DROPS / ORAL | 210 mg/1ml | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | AEROSOL, SPRAY / TOPICAL | 561 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SOLUTION, CONCENTRATE / ORAL | 150.68 mg/1ml | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | INJECTION, EMULSION / INTRAVENOUS | 520 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SOLUTION / TRANSDERMAL | 49.37 %w/v | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | POWDER, FOR SOLUTION / TOPICAL | 40 %w/w | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SYRUP / ORAL | 21000 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | LOTION / TOPICAL | 25 %w/w | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SPRAY / TOPICAL | 3633 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | ELIXIR / ORAL | 13675 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | CAPSULE, EXTENDED RELEASE / ORAL | 8 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SOLUTION / TOPICAL | 2445 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | AEROSOL / NASAL | 20 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SHAMPOO / TOPICAL | 714 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | LIQUID / ORAL | 3563 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | GEL, METERED / TOPICAL | 541 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | INJECTION / SUBCUTANEOUS | 149 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | INJECTION / INTRAMUSCULAR | 1491 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SPRAY / SUBLINGUAL | 397 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | PASTE / DENTAL | 1.8 %w/w | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | INJECTION / INTRAVASCULAR | 100 %v/v | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | JELLY / VAGINAL | NA | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | INJECTION, SOLUTION / INTRAMUSCULAR | 1000 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SOLUTION / NASAL | 10 mg/1ml | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SOLUTION / INTRAVENOUS | 99 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | AEROSOL, METERED / RESPIRATORY (INHALATION) | 26664 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | CAPSULE / ORAL | 882 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | GEL / RECTAL | 898 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | CONCENTRATE / ORAL | 198 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SOLUTION, CONCENTRATE / INTRAVENOUS | 4000 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SPRAY, METERED / SUBLINGUAL | 29 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SWAB / TOPICAL | 2250 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | INJECTION, SOLUTION / SUBCUTANEOUS | 6.1 %v/v | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | LIQUID / RESPIRATORY (INHALATION) | 5 %w/w | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | GEL / DENTAL | 1.8 %w/w | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | AEROSOL, METERED / NASAL | 70 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SPRAY / TRANSDERMAL | 90 %w/v | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | AEROSOL / TOPICAL | 561 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SOLUTION / INTRAVESICAL | 7892 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SPRAY / NASAL | 20 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | GEL / TOPICAL | 9971 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SOLUTION / RESPIRATORY (INHALATION) | 0.08 %w/v | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | AEROSOL, SPRAY / RESPIRATORY (INHALATION) | 35.75 %w/w | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | GEL, METERED / TRANSDERMAL | 3675 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SUSPENSION / ORAL | 681 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SUSPENSION / RECTAL | 0.35 %v/v | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SOLUTION / DENTAL | 12.8 %w/w | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | INJECTION, SOLUTION / INTRAVENOUS | 6405 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SOLUTION / ORAL | 6624 mg | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | CONCENTRATE / BUCCAL | 679 mg/1ml | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | TABLET, DELAYED RELEASE / ORAL | NA | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | AEROSOL, FOAM / TOPICAL | 4504 mg |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| 008d2cb1-f8ff-4f95-9e75-d8ddedf2ecee | 05ab659e-c5de-4492-8b76-58be39aa1f76 | 2012-02-06 | Warnings | 008d2cb1-f8ff-4f95-9e75-d8ddedf2ecee 05ab659e-c5de-4492-8b76-58be39aa1f76 |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.