Storage and handling
Other Information • read the directions and warnings before use • keep the carton. It contains important information. • store at 20-25°C (68-77°F)
Other Information • read the directions and warnings before use • keep the carton. It contains important information. • store at 20-25°C (68-77°F)
Active ingredient (in each tablet)
Esomeprazole 20 mg
(Each delayed-release tablet corresponds to 22.3 mg esomeprazole magnesium trihydrate)
Purpose
Acid reducer
Uses
Warnings
If an allergic reaction occurs, stop use and seek medical attention right away.
These may be signs of a serious condition. See your doctor.
Ask a doctor or pharmacist before use if you are
If pregnant or breast-feeding, ask a health professional before use.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Directions
Other Information
Inactive ingredients
corn starch, crospovidone, D&C red no. 27 aluminum lake, FD&C blue no. 2 aluminum lake, FD&C red no. 40 aluminum lake, glyceryl monostearate, hydroxypropyl cellulose, hypromellose, magnesium stearate, methacrylic acid copolymer, mica, microcrystalline cellulose, paraffin, polyethylene glycol, polysorbate 80, sodium stearyl fumarate, sucrose, talc, titanium dioxide, triethyl citrate
Questions or comments?
call toll-free weekdays 9 AM to 5 PM EST at 1-866-226-1600
KEEP CARTON FOR COMPLETE WARNINGS AND IMPORTANT INFORMATION.
Do Not Use if seal under bottle cap imprinted with “SEALED for YOUR PROTECTION”
or yellow band around the center of each capsule is broken or missing.
Tips for Managing Heartburn
Distributed by: GSK Consumer Healthcare,
Warren, NJ 07059
©2022 GSK group of companies or its licensor
Made in France
For most recent product information, visit
www.Nexium24HR.com
Nexium is a registered trademark of AstraZeneca AB and is used under license.
| RxCUI | RxNorm string | TTY | SPL version |
|---|---|---|---|
| 433733 | esomeprazole magnesium 20 MG Delayed Release Oral Tablet | PSN | 12 |
| 1743279 | NexIUM 20 MG Delayed Release Oral Tablet | PSN | 12 |
| 1743279 | esomeprazole 20 MG Delayed Release Oral Tablet [Nexium] | SBD | 12 |
| 433733 | esomeprazole 20 MG Delayed Release Oral Tablet | SCD | 12 |
| 433733 | esomeprazole 20 MG (as esomeprazole magnesium 22.3 MG) Delayed Release Oral Tablet | SY | 12 |
| 1743279 | Nexium 20 MG (as esomeprazole magnesium 22.3 MG) Delayed Release Oral Tablet | SY | 12 |
| 1743279 | Nexium 20 MG Delayed Release Oral Tablet | SY | 12 |
| 1743279 | Nexium 24 HR 20 MG Delayed Release Oral Tablet | SY | 12 |
| Class | Version | Type | Effective |
|---|---|---|---|
| ESOMEPRAZOLE Pharmacologic Class Indexing | 3 | Indexing - Pharmacologic Class | 20180813 |
| Product concept | Relation | Version | Effective |
|---|---|---|---|
| d7006a36-e68d-42e2-8cd3-d725cb2e47b1 | Product name | 6 | 20251027 |
| d71865e8-5c35-4d76-8ecd-a7adda982240 | Product name | 9 | 20180628 |
| d71865e8-5c35-4d76-8ecd-a7adda982240 | Product name | 8 | 20171212 |
| 094c6751-235c-4d12-acee-2baf94f676f4 | Product name | 1 | 20151116 |
| ce67e27d-1d21-5465-4409-b0662dd99d4d | Product name | 1 | 20140508 |
| NDC | Effective | Action | Document | Indexing SPL | Related label |
|---|---|---|---|---|---|
| 0573-2451-14 | 2024-01-30 | C162847 | 48780-1 | 1030e365-09e6-111a-e063-dadaa90a10e2 | Drug Facts |
| 0573-2451-14 | 2024-01-30 | C162847 | 48780-1 | 1030e365-09e6-111a-e063-dadaa90a10e2 | Drug Facts |
| 0573-2451-28 | 2024-01-30 | C162847 | 48780-1 | 1030e365-09e6-111a-e063-dadaa90a10e2 | Drug Facts |
| 0573-2451-28 | 2024-01-30 | C162847 | 48780-1 | 1030e365-09e6-111a-e063-dadaa90a10e2 | Drug Facts |
| 0573-2451-42 | 2024-01-30 | C162847 | 48780-1 | 1030e365-09e6-111a-e063-dadaa90a10e2 | Drug Facts |
| 0573-2451-42 | 2024-01-30 | C162847 | 48780-1 | 1030e365-09e6-111a-e063-dadaa90a10e2 | Drug Facts |
| 0573-2451-43 | 2024-01-30 | C162847 | 48780-1 | 1030e365-09e6-111a-e063-dadaa90a10e2 | Drug Facts |
| 0573-2451-43 | 2024-01-30 | C162847 | 48780-1 | 1030e365-09e6-111a-e063-dadaa90a10e2 | Drug Facts |
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 0573-2451-14 | Nexium 24HR | 1 in 1 CARTON | TABLET | 1 | 12 | |
| 0573-2451-14 | Nexium 24HR | 14 in 1 BOTTLE | TABLET | 14 | 12 | |
| 0573-2451-28 | Nexium 24HR | 14 in 1 BOTTLE | TABLET | 14 | 12 | |
| 0573-2451-28 | Nexium 24HR | 2 in 1 CARTON | TABLET | 2 | 12 | |
| 0573-2451-42 | Nexium 24HR | 3 in 1 BLISTER PACK | TABLET | 3 | 12 | |
| 0573-2451-42 | Nexium 24HR | 14 in 1 BOTTLE | TABLET | 14 | 12 | |
| 0573-2451-43 | Nexium 24HR | 14 in 1 BOTTLE | TABLET | 14 | 12 | |
| 0573-2451-43 | Nexium 24HR | 3 in 1 PACKAGE | TABLET | 3 | 12 |
| Package NDC | Billing unit | Product NDC | DailyMed indexing SPL | SPL version | Effective |
|---|---|---|---|---|---|
| 0573-2451-14 | EA - Each | 0573-2451 | 665a123b-947f-4789-b55e-a6ba8f01e738 | 1 | 2016-04-04 |
| 0573-2451-42 | EA - Each | 0573-2451 | f4b1c017-209f-4f80-95a9-2a5a09c54870 | 1 | 2016-04-04 |
Every source-derived product name is available through these pages.
| Product NDC | Package NDC |
|---|---|
| 0573-2451 | 0573-2451-14, 0573-2451-42, 0573-2451-28, 0573-2451-43 |
Every source-derived ingredient row is available through these pages.
| Version | Effective date | Source | Hydrated |
|---|---|---|---|
| 11 | 2024-03-19 | full-release | 2026-06-01 00:10:02 |
All distinct exact application/product contexts derived from this label’s complete NDC list are paginated below.
| Application-product | Trade name | Ingredient | Strength | Dosage form / route | TE codes | RLD / RS | Approval date |
|---|---|---|---|---|---|---|---|
| N207920-001 | NEXIUM 24HR | ESOMEPRAZOLE MAGNESIUM | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 |
Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
| Captured | Edition | Application-product | Trade name | Strength | Dosage form / route | Product TE source text | RLD / RS | Approval date | Source SHA-256 |
|---|---|---|---|---|---|---|---|---|---|
| 2026-10-15 13:18:30 | 2026-09 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | c2088c7a36db… | |
| 2026-09-14 22:38:34 | 2026-08 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 84e616aacf4f… | |
| 2026-08-18 06:07:40 | 2026-07 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | caaa826d4ba7… | |
| 2026-02-19 14:30 UTC | 2026-02 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 011fe1cb6892… | |
| 2025-12-14 10:44 UTC · 2 captures of this ZIP | 2025-12 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 31067a03dcf5… | |
| 2025-08-23 18:47 UTC | 2025-08 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 6a471c1ec25d… | |
| 2025-03-22 03:13 UTC · 3 captures of this ZIP | 2025-03 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | fd3edfee7708… | |
| 2025-02-26 10:13 UTC · 3 captures of this ZIP | 2025-02 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | b8a1b40f171c… | |
| 2025-01-19 17:59 UTC · 7 captures of this ZIP | 2025-01 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 03ed91905a0d… | |
| 2024-12-13 21:23 UTC · 2 captures of this ZIP | 2024-12 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 2680178bc6a6… | |
| 2024-09-14 05:58 UTC · 2 captures of this ZIP | 2024-09 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 5bbf6a4d5a75… | |
| 2024-11-08 22:44 UTC · 3 captures of this ZIP | 2024-11 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | d8e5a09893c0… | |
| 2024-10-29 15:01 UTC | 2024-10 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | d06236e962d9… | |
| 2024-08-13 05:28 UTC · 3 captures of this ZIP | 2024-08 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 79d66fd596c7… | |
| 2024-07-13 05:37 UTC · 2 captures of this ZIP | 2024-07 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 301d65b070ca… | |
| 2024-06-18 03:08 UTC · 5 captures of this ZIP | 2024-06 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 1e350fbaab3a… | |
| 2024-05-31 18:47 UTC | 2024-05 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 8072bd15b7f6… | |
| 2022-06-29 02:47 UTC · 2 captures of this ZIP | 2022-06 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 5c6f7cd8ea54… | |
| 2022-04-08 23:34 UTC | 2022-04 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 5d02ea3f76ae… | |
| 2022-04-04 05:41 UTC | 2022-04 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 4b0b4de00fa7… | |
| 2019-12-13 00:20 UTC | 2019-12 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 74a2ff9319b5… | |
| 2022-03-09 01:35 UTC | 2022-03 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | bb7c543d1eb4… | |
| 2021-12-28 21:50 UTC | 2021-12 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 782e0a99824c… | |
| 2021-05-05 16:15 UTC · 3 captures of this ZIP | 2021-05 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 87673890dc5c… | |
| 2021-03-12 10:30 UTC | 2021-03 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 5aa47cf7b7d7… | |
| 2020-12-22 03:56 UTC | 2020-12 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 8869cabd3fbd… | |
| 2020-11-12 02:37 UTC | 2020-11 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | c0c555d07b60… | |
| 2019-12-14 00:12 UTC | 2019-12 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 3f01610625f2… | |
| 2019-09-15 20:21 UTC | 2019-09 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | b00525d2431f… | |
| 2019-07-19 19:46 UTC | 2019-07 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | ea99ee380514… | |
| 2024-03-16 18:09 UTC · 4 captures of this ZIP | 2024-03 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 6a51e52b5d6a… | |
| 2024-02-18 07:12 UTC | 2024-02 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 1c564ffb4f44… | |
| 2023-12-20 04:57 UTC | 2023-12 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | ea1830bbd6c7… | |
| 2023-11-28 05:40 UTC · 2 captures of this ZIP | 2023-11 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | a72a2bbeb626… | |
| 2023-10-25 00:34 UTC · 2 captures of this ZIP | 2023-10 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 9b2671bbb829… | |
| 2023-07-15 15:27 UTC · 2 captures of this ZIP | 2023-07 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | a67488948f0b… | |
| 2023-06-13 01:57 UTC · 3 captures of this ZIP | 2023-06 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 3f0d92c62455… | |
| 2023-05-13 08:27 UTC | 2023-05 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 053a50430f4f… | |
| 2023-01-26 05:58 UTC | 2023-01 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 3bdfa0b2c4d7… | |
| 2022-11-12 20:34 UTC · 5 captures of this ZIP | 2022-11 | N207920-001 | NEXIUM 24HR | EQ 20MG BASE | TABLET, DELAYED RELEASE / ORAL | RLD, RS | 2015-11-23 | 3a93d1ddd44b… |
| Captured | Edition | Application-product | Patent | Expiration | Use code | Coverage / status | Submission date | Source SHA-256 |
|---|---|---|---|---|---|---|---|---|
| 2019-12-13 00:20 UTC | 2019-12 | N207920-001 | 6428810 | 2019-11-03 | U-1785 | Drug product | 2015-12-18 | 74a2ff9319b5… |
| 2019-12-13 00:20 UTC | 2019-12 | N207920-001 | 6428810*PED | 2020-05-03 | Pediatric extension | 74a2ff9319b5… | ||
| 2020-12-22 03:56 UTC | 2020-12 | N207920-001 | 6428810*PED | 2020-05-03 | Pediatric extension | 8869cabd3fbd… | ||
| 2020-11-12 02:37 UTC | 2020-11 | N207920-001 | 6428810*PED | 2020-05-03 | Pediatric extension | c0c555d07b60… | ||
| 2019-12-14 00:12 UTC | 2019-12 | N207920-001 | 6428810 | 2019-11-03 | U-1785 | Drug product | 2015-12-18 | 3f01610625f2… |
| 2019-12-14 00:12 UTC | 2019-12 | N207920-001 | 6428810*PED | 2020-05-03 | Pediatric extension | 3f01610625f2… | ||
| 2019-09-15 20:21 UTC | 2019-09 | N207920-001 | 6428810 | 2019-11-03 | U-1785 | Drug product | 2015-12-18 | b00525d2431f… |
| 2019-09-15 20:21 UTC | 2019-09 | N207920-001 | 6428810*PED | 2020-05-03 | Pediatric extension | b00525d2431f… | ||
| 2019-07-19 19:46 UTC | 2019-07 | N207920-001 | 6428810 | 2019-11-03 | U-1785 | Drug product | 2015-12-18 | ea99ee380514… |
| 2019-07-19 19:46 UTC | 2019-07 | N207920-001 | 6428810*PED | 2020-05-03 | Pediatric extension | ea99ee380514… |
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Nexium 24HR | ESOMEPRAZOLE MAGNESIUM | Haleon US Holdings LLC | 61f67858-ba2f-449b-8b30-c15cdaf49222 | 2025-01-09 | Warnings | 0573-2451-43 0573-2451-28 0573-2451-42 0573-2451-14 0573-2451 00573245142 00573245143 00573245128 00573245114 9e3651ca-65ce-430f-9036-1f7e42629a79 61f67858-ba2f-449b-8b30-c15cdaf49222 |
Adverse event summaries are temporarily unavailable. Other product information remains available.