API General Cure

Manufacturer
MARS FISHCARE NORTH AMERICA, INC. | Alivira Animal Health Limited
Effective date
2022-04-19
Label type
OTC ANIMAL DRUG LABEL
Version
6
Source
full-release
Hydrated at
2026-06-01 02:41:23

Label at a glance#

ProductAPI General Cure
Active ingredientMETRONIDAZOLE, PRAZIQUANTEL
Label structure5 sections

Label contents#

Full prescribing information#

OTC - ACTIVE INGREDIENT SECTION

Active Ingredients: 250 mg Metronidazole and 75 mg Praziquantel per packet.

DOSAGE & ADMINISTRATION SECTION

Directions for Use:

For best results, remove activated carbon or filter cartridge from filter and continue aeration.

For each 10 gallons (38 L) of water, empty one packet directly into aquarium.

Repeat dose after 48 hours.

Wait another 48 hours then change 25% of the aquarium water and add fresh activated carbon or replace filter cartridge.

This package treats up to 100 gallons.

Two doses required for full course of treatment.

Will not discolor water

Safe for use with live plants.

INDICATIONS & USAGE SECTION

Diagnostic Chart

Gill and Skin Flukes:

Very common fish parasite. Can be found on the gills, scales or skin. Not visible without the aid of magnification. Symptoms may include: darkening of skin, clamped fins, excess mucous. Fish may also swim erratically or become emaciated.

Hole-in-the-Head Disease:

Symptoms include pitting and erosion of skin and muscle tissue around the face and side of body. Many infected fish exhibit poor appetite, weight loss and nervousness.

Wasting Disease:

Fish parasites transmitted from fish to fish cause emaciation, anemia and lethargy. Tissue damage leading to subsequent ulceration of the gastrointestinal tract. Excess mucus and white stringy feces are often produced as a result of parasitic invasion.

Swollen Abdomen:

Fish infected with tapeworms (cestodes), often have an extended or swollen abdomen. Internal areas of attachment results in damaged tissue. Fish normally show signs of reduction in growth and general malaise.

WARNINGS AND PRECAUTIONS SECTION

KEEP OUT OF THE REACH OF CHILDREN.

For aquarium use only.

Not for human consumption or for the treatment of fish intended for human consumption.

Avoid contact with skin and eyes.

May cause irritation.

! WARNING:

This product can expose you to chemicals including Metronidazole, which is known to the State of California to cause cancer.

For more information go to www.P65Warnings.ca.gov.

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

Diagnostic Chart

On Back

10

Powder

Packets

Use In Fresh and Saltwater Aquariums

API

GENERAL CURE

TREATS PARASITIC FISH DISEASE

Eliminates a wide variety of parasites

Fast acting

Gill and Skin Flukes

Hole-in-the-Head

Swollen Abdomen

Wasting Disease

GUIDE

Fish Problem

Solving

container labelFcontainer labelF

container labelBcontainer labelB

container labelFcontainer labelFcontainer labelBcontainer labelB

DailyMed Pharmacologic Classes#

Class, Version, Type table
ClassVersionTypeEffective
METRONIDAZOLE Pharmacologic Class Indexing2Indexing - Pharmacologic Class20180813
PRAZIQUANTEL Pharmacologic Class Indexing3Indexing - Pharmacologic Class20190712

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
8ffb9b1d-3ed7-ba2e-677e-47d4d134fd55Product name520251024
7f6d14e0-4366-41bc-a4a9-b74c79a20e17Product name120250623
e6d321b0-0e5e-7da6-f043-92b6a91f00a1Product name520250515
e1aac33b-94ae-4ee9-905b-299f7263853bProduct name320250124
16642716-d28a-4f90-8dcb-3921cd8c8109Product name420240516
0be8e4ae-4d57-49f3-b3a9-e4728b4e8d15Product name120240313
dea2eded-d1e7-46bb-9a3d-f8dc20de6277Product name120190408
a5070875-62bb-61e1-fd46-8f7054197a40Product name820180215
8cabd598-669e-43ab-9753-4aec00a484cbProduct name120180125
0add4de9-d152-3375-3390-1123dddc5e3dProduct name120140508
33ca0fcc-1011-92dc-50a9-a383683eed1eProduct name120140508
53f39d9f-cd3f-04e1-c668-d4580719d57dProduct name120140508
a804000f-b74f-0b5d-d17b-aa767c286ddbProduct name120140508
a91ea265-6e02-c08f-93c8-686d54180529Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
17163-015-16API General Cure2 g in 1 PACKETPOWDER26
17163-015-16API General Cure10 in 1 BOXPOWDER106

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
17163-015API GENERAL CURE (METRONIDAZOLE PRAZIQUANTEL) POWDER [MARS FISHCARE NORTH AMERICA, INC.]62 package rows20220420_22e84714-366b-4a90-89e2-eae934716af4.zip

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 4 matching rows.

NDC Codes#

Product NDC, Package NDC table
Product NDCPackage NDC
17163-01517163-015-16

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 2 matching rows.

Name, UNII, Kind table
NameUNIIKind
METRONIDAZOLE140QMO216EACTIB
PRAZIQUANTEL6490C9U457ACTIB

Source Document#

Source XML

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 8 · 147 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
MetronidazoleMETRONIDAZOLENuCare Pharmaceuticals, Inc.4040db14-750f-6d20-e054-00144ff8d46c2026-08-26Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLEMajor Pharmaceuticals71f5ce2f-17f8-45fc-b27d-2bf982591ab32026-08-21Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLEREMEDYREPACK INC.5cc3fd98-d579-432e-a4b5-b6d5586991a62026-08-05Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLEREMEDYREPACK INC.dc28753c-95ec-4b41-ad77-c4a66698d9db2026-08-04Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
metronidazoleMETRONIDAZOLEREMEDYREPACK INC.b49a8ad0-2cf9-4386-8bf5-1b1df87b00222026-08-03Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
metronidazoleMETRONIDAZOLEREMEDYREPACK INC.d5784eeb-6b99-4e8a-847b-b0d1090ed48a2026-07-28Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLEREMEDYREPACK INC.2f7d84d4-1085-4243-be88-442eecb852052026-07-22Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
VagizoleMETRONIDAZOLEiNutrition LLCfd5e884b-cf07-493b-bb93-039bbb0c47842026-07-22Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLEBryant Ranch Prepack5cf3cc1f-601e-4997-bfb2-a573c31c81892026-07-15Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLESun Pharmaceutical Industries, Inc.4a233572-2471-4e99-a45e-2de978abcf162026-07-15Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLESun Pharmaceutical Industries, Inc.5a504f74-bccd-433a-bd5b-6822f98c34df2026-07-15Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLESun Pharmaceutical Industries, Inc.5842a554-58d1-4ee4-99aa-1e6029a69be22026-07-15Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLEBryant Ranch Prepack4748ba37-9d66-497d-aa9f-ca2d541c5f412026-07-15Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLEPreferred Pharmaceuticals Inc.59e53582-244a-4e9d-b18e-75dddc6a50522026-07-08Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLEREMEDYREPACK INC.cfeab9e3-58b9-4890-9185-11b62904e2af2026-07-07Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLEPreferred Pharmaceuticals Inc.cbee69e8-029c-49d2-89cd-f504b8e0ac282026-07-07Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLEPreferred Pharmaceuticals Inc.3e0a14f1-961b-4722-bfea-aafcc5d7706c2026-07-07Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLEREMEDYREPACK INC.53918705-d2fe-4c6b-9501-a619a8ad39912026-07-03Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
MetronidazoleMETRONIDAZOLEKanchan Healthcare Inc8836334e-6db4-44be-bc9e-099b26322cf42026-07-01Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE
metronidazoleMETRONIDAZOLEBryant Ranch Prepack99886f54-4ebe-4a2d-b779-bcfbb0634db12026-06-30Boxed warning, Warnings, Adverse reactionsName fallback
generic name: METRONIDAZOLE

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.