API General Cure
- Manufacturer
- MARS FISHCARE NORTH AMERICA, INC. | Alivira Animal Health Limited
- Effective date
- 2022-04-19
- Label type
- OTC ANIMAL DRUG LABEL
- Version
- 6
- Source
- full-release
- Hydrated at
- 2026-06-01 02:41:23
Label at a glance#
Contacts and useful links#
Label contents#
Full prescribing information#
OTC - ACTIVE INGREDIENT SECTION
Active Ingredients: 250 mg Metronidazole and 75 mg Praziquantel per packet.
DOSAGE & ADMINISTRATION SECTION
Directions for Use:
For best results, remove activated carbon or filter cartridge from filter and continue aeration.
For each 10 gallons (38 L) of water, empty one packet directly into aquarium.
Repeat dose after 48 hours.
Wait another 48 hours then change 25% of the aquarium water and add fresh activated carbon or replace filter cartridge.
This package treats up to 100 gallons.
Two doses required for full course of treatment.
Will not discolor water
Safe for use with live plants.
INDICATIONS & USAGE SECTION
Diagnostic Chart
Gill and Skin Flukes:
Very common fish parasite. Can be found on the gills, scales or skin. Not visible without the aid of magnification. Symptoms may include: darkening of skin, clamped fins, excess mucous. Fish may also swim erratically or become emaciated.
Hole-in-the-Head Disease:
Symptoms include pitting and erosion of skin and muscle tissue around the face and side of body. Many infected fish exhibit poor appetite, weight loss and nervousness.
Wasting Disease:
Fish parasites transmitted from fish to fish cause emaciation, anemia and lethargy. Tissue damage leading to subsequent ulceration of the gastrointestinal tract. Excess mucus and white stringy feces are often produced as a result of parasitic invasion.
Swollen Abdomen:
Fish infected with tapeworms (cestodes), often have an extended or swollen abdomen. Internal areas of attachment results in damaged tissue. Fish normally show signs of reduction in growth and general malaise.
WARNINGS AND PRECAUTIONS SECTION
KEEP OUT OF THE REACH OF CHILDREN.
For aquarium use only.
Not for human consumption or for the treatment of fish intended for human consumption.
Avoid contact with skin and eyes.
May cause irritation.
! WARNING:
This product can expose you to chemicals including Metronidazole, which is known to the State of California to cause cancer.
For more information go to
www.P65Warnings.ca.gov.
PACKAGE LABEL.PRINCIPAL DISPLAY PANEL
Diagnostic Chart
On Back
10
Powder
Packets
Use In Fresh and Saltwater Aquariums
API
GENERAL CURE
TREATS PARASITIC FISH DISEASE
Eliminates a wide variety of parasites
Fast acting
Gill and Skin Flukes
Hole-in-the-Head
Swollen Abdomen
Wasting Disease
GUIDE
Fish Problem
Solving
DailyMed Pharmacologic Classes#
| Class | Version | Type | Effective |
|---|---|---|---|
| METRONIDAZOLE Pharmacologic Class Indexing | 2 | Indexing - Pharmacologic Class | 20180813 |
| PRAZIQUANTEL Pharmacologic Class Indexing | 3 | Indexing - Pharmacologic Class | 20190712 |
DailyMed Product Concepts#
| Product concept | Relation | Version | Effective |
|---|---|---|---|
| 8ffb9b1d-3ed7-ba2e-677e-47d4d134fd55 | Product name | 5 | 20251024 |
| 7f6d14e0-4366-41bc-a4a9-b74c79a20e17 | Product name | 1 | 20250623 |
| e6d321b0-0e5e-7da6-f043-92b6a91f00a1 | Product name | 5 | 20250515 |
| e1aac33b-94ae-4ee9-905b-299f7263853b | Product name | 3 | 20250124 |
| 16642716-d28a-4f90-8dcb-3921cd8c8109 | Product name | 4 | 20240516 |
| 0be8e4ae-4d57-49f3-b3a9-e4728b4e8d15 | Product name | 1 | 20240313 |
| dea2eded-d1e7-46bb-9a3d-f8dc20de6277 | Product name | 1 | 20190408 |
| a5070875-62bb-61e1-fd46-8f7054197a40 | Product name | 8 | 20180215 |
| 8cabd598-669e-43ab-9753-4aec00a484cb | Product name | 1 | 20180125 |
| 0add4de9-d152-3375-3390-1123dddc5e3d | Product name | 1 | 20140508 |
| 33ca0fcc-1011-92dc-50a9-a383683eed1e | Product name | 1 | 20140508 |
| 53f39d9f-cd3f-04e1-c668-d4580719d57d | Product name | 1 | 20140508 |
| a804000f-b74f-0b5d-d17b-aa767c286ddb | Product name | 1 | 20140508 |
| a91ea265-6e02-c08f-93c8-686d54180529 | Product name | 1 | 20140508 |
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 17163-015-16 | API General Cure | 2 g in 1 PACKET | POWDER | 2 | 6 | |
| 17163-015-16 | API General Cure | 10 in 1 BOX | POWDER | 10 | 6 |
DailyMed Dashboard NDC Coverage#
Products#
Every source-derived product name is available through these pages.
- API General Cure
- Metronidazole Praziquantel
- METRONIDAZOLE
- PRAZIQUANTEL
NDC Codes#
| Product NDC | Package NDC |
|---|---|
| 17163-015 | 17163-015-16 |
Ingredients#
Every source-derived ingredient row is available through these pages.
| Name | UNII | Kind |
|---|---|---|
| METRONIDAZOLE | 140QMO216E | ACTIB |
| PRAZIQUANTEL | 6490C9U457 | ACTIB |
Source Document#
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Metronidazole | METRONIDAZOLE | NuCare Pharmaceuticals, Inc. | 4040db14-750f-6d20-e054-00144ff8d46c | 2026-08-26 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Major Pharmaceuticals | 71f5ce2f-17f8-45fc-b27d-2bf982591ab3 | 2026-08-21 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | 5cc3fd98-d579-432e-a4b5-b6d5586991a6 | 2026-08-05 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | dc28753c-95ec-4b41-ad77-c4a66698d9db | 2026-08-04 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | b49a8ad0-2cf9-4386-8bf5-1b1df87b0022 | 2026-08-03 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | d5784eeb-6b99-4e8a-847b-b0d1090ed48a | 2026-07-28 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | 2f7d84d4-1085-4243-be88-442eecb85205 | 2026-07-22 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Vagizole | METRONIDAZOLE | iNutrition LLC | fd5e884b-cf07-493b-bb93-039bbb0c4784 | 2026-07-22 | Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Bryant Ranch Prepack | 5cf3cc1f-601e-4997-bfb2-a573c31c8189 | 2026-07-15 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Sun Pharmaceutical Industries, Inc. | 4a233572-2471-4e99-a45e-2de978abcf16 | 2026-07-15 | Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Sun Pharmaceutical Industries, Inc. | 5a504f74-bccd-433a-bd5b-6822f98c34df | 2026-07-15 | Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Sun Pharmaceutical Industries, Inc. | 5842a554-58d1-4ee4-99aa-1e6029a69be2 | 2026-07-15 | Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Bryant Ranch Prepack | 4748ba37-9d66-497d-aa9f-ca2d541c5f41 | 2026-07-15 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Preferred Pharmaceuticals Inc. | 59e53582-244a-4e9d-b18e-75dddc6a5052 | 2026-07-08 | Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | cfeab9e3-58b9-4890-9185-11b62904e2af | 2026-07-07 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Preferred Pharmaceuticals Inc. | cbee69e8-029c-49d2-89cd-f504b8e0ac28 | 2026-07-07 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Preferred Pharmaceuticals Inc. | 3e0a14f1-961b-4722-bfea-aafcc5d7706c | 2026-07-07 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | REMEDYREPACK INC. | 53918705-d2fe-4c6b-9501-a619a8ad3991 | 2026-07-03 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| Metronidazole | METRONIDAZOLE | Kanchan Healthcare Inc | 8836334e-6db4-44be-bc9e-099b26322cf4 | 2026-07-01 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
| metronidazole | METRONIDAZOLE | Bryant Ranch Prepack | 99886f54-4ebe-4a2d-b779-bcfbb0634db1 | 2026-06-30 | Boxed warning, Warnings, Adverse reactions | METRONIDAZOLE |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.

