Droncit ® (praziquantel tablets) 23 Feline Cestocide may be administered directly per os or crumbled and mixed with the feed. The recommended dosage of praziquantel varies according to body weight. Smaller animals require a relatively larger dosage because of their higher metabolic rate. The optimum dose for each individual animal will be achieved by utilizing the following dosage schedule: Cats and Kittens Not ...
CAUTION: Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian.
Each Tablet Contains 23 mg Praziquantel
DESCRIPTION:
DESCRIPTION SECTION
Droncit®(praziquantel tablets) 23 Feline Cestocide are sized for easy oral administration to either adult cats or kittens. The tablets may be crumbled and mixed with the feed.
INDICATIONS:
INDICATIONS & USAGE SECTION
Droncit®(praziquantel tablets) 23 Feline Cestocide are indicated for the removal of the following feline cestodes: Dipylidium caninum and Taenia taeniaeformis.
CONTRAINDICATIONS:
CONTRAINDICATIONS SECTION
There are no known contraindications to the use of praziquantel in cats.
ACTION:
MECHANISM OF ACTION SECTION
Droncit®(praziquantel tablets) is absorbed, metabolized in the liver and excreted in the bile. Upon entering the digestive tract from the bile, cestocidal activity is exhibited.1
Following exposure to praziquantel, the tapeworm loses its ability to resist digestion by the mammalian host. Because of this, whole tapeworms, including the scolex, are very rarely passed after administration of praziquantel. In many instances only disintegrated and partially digested pieces of tapeworms will be seen in the stool. The majority of tapeworms killed are digested and are not found in the feces.
USE DIRECTIONS:
DOSAGE & ADMINISTRATION SECTION
Droncit®(praziquantel tablets) 23 Feline Cestocide may be administered directly per os or crumbled and mixed with the feed. The recommended dosage of praziquantel varies according to body weight. Smaller animals require a relatively larger dosage because of their higher metabolic rate. The optimum dose for each individual animal will be achieved by utilizing the following dosage schedule:
* Not intended for use in kittens less than 6 weeks of age.
FASTING:
SPL UNCLASSIFIED SECTION
The recommended dosage of praziquantel is not affected by the presence or absence of food in the gastrointestinal tract, therefore, FASTING IS NEITHER NECESSARY NOR RECOMMENDED.
RETREATMENT:
SPL UNCLASSIFIED SECTION
For those animals maintained on premises where reinfections are likely to occur, clients should be instructed in the steps necessary to prevent reinfection; otherwise, retreatment may be necessary. This is especially true in cases of Dipylidium caninum infections where reinfection is almost certain to occur if fleas are not removed from the animal and its environment.
ANIMAL SAFETY:
ANIMAL PHARMACOLOGY & OR TOXICOLOGY SECTION
The safety index has been derived from controlled safety evaluations, clinical trials and prior approved use in foreign countries.
Dosages of 5 times the labeled rate at 14 day intervals to cats as young as 5 ½ weeks did not produce clinical signs of toxicity. No significant clinical chemistry, hematological, or histopathological changes occurred. Symptoms of gross overdosage include vomition, salivation, diarrhea and depression.
PREGNANCY:
PREGNANCY SECTION
Droncit®(praziquantel tablets) has been tested in breeding and pregnant cats. No adverse effects were noted.
ADVERSE REACTIONS:
ADVERSE REACTIONS SECTION
One instance of diarrhea and one of salivation (1.5%) were reported during the field trials in which 135 cats were administered Droncit®(praziquantel tablets) 23 Feline Cestocide.
For medical emergencies or to report adverse reactions, call 1-800-422-9874.
WARNING:
WARNINGS SECTION
Keep out of the reach of children. Not for human use.
For customer service or to obtain product information, including Safety Data Sheet, call 1-800-633-3796.
STORAGE:
SPL UNCLASSIFIED SECTION
Store at less than or equal to 25°C (77°F)
HOW SUPPLIED:
HOW SUPPLIED SECTION
Bottle of 50 and 150 scored tablets. Each scored tablet contains 23 mg praziquantel.
50 Tablets
150 Tablets
REFERENCES:
REFERENCES SECTION
1 Andrews, P. Pharmacokinetic Studies with Droncit in Animals Using a Biological Assay. Veterinary Medical Review 2/76: 154-165.
SPL UNCLASSIFIED SECTION
Bayer Logo
Bayer HealthCare LLC, Animal Health Division Shawnee Mission, Kansas 66201 U.S.A. NADA 111-798, Approved by FDA Made in Germany
Bayer, the Bayer Cross, and Droncit are registered trademarks of Bayer.
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