Indications and uses
For the management of acne. Clears up most acne pimples, blackheads, and whiteheads and allows skin to heal. Penetrates pores to eliminate most acne blemishes. Helps prevent new acne pimples.
Kleer-Plex Advanced Acne Care System
- Manufacturer
- Bio-Medical & Pharmaceutical Manufacturing Corporation
- Effective date
- 2014-11-03
- Label type
- HUMAN OTC DRUG LABEL
- Version
- 4
- Source
- full-release
- Hydrated at
- 2026-05-31 22:40:43
Label at a glance#
ProductKleer-Plex Advanced Acne Care System
Active ingredientSALICYLIC ACID
Label structure13 sections
Dosage and administration
Acne Treatment Wash At least once each day, dispense a small amount of cleanser onto an exfoliating pad or cloth. Add a small amount of water and work into a lather on the face using small circular motions avoiding the eyes. Repeat after perspiration or makeup use. If dryness occurs, reduce frequency to once each day. Acne Treatment Gel Each night, dispense a small amount of gel onto the fingertips. Spread gel spa...
Contacts and useful links#
Label contents#
Full prescribing information#
THIS SYSTEM CONTAINS:
(1) Foaming Acne Clarifier
NDC 37945-870-40
(1) Pore Purifier & Toner
(1) Penetrating Acne Gel
NDC 37945-874-11
(1) Targeted Acne Pen
NDC 37945-894-05
DRUG FACTS
Acne Treatment Wash and Acne Treatment Gel
Active Ingredient
Salicylic Acid, 2%
Purpose
Acne Treatment
Uses
- For the management of acne.
- Clears up most acne pimples, blackheads, and whiteheads and allows skin to heal.
- Penetrates pores to eliminate most acne blemishes.
- Helps prevent new acne pimples.
Warnings
For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time.
- If irritation occurs, only use one topical acne medication at a time.
OTC - KEEP OUT OF REACH OF CHILDREN SECTION
KEEP OUT OF REACH OF CHILDREN
Directions
Acne Treatment Wash
- At least once each day, dispense a small amount of cleanser onto an exfoliating pad or cloth.
- Add a small amount of water and work into a lather on the face using small circular motions avoiding the eyes.
- Repeat after perspiration or makeup use.
- If dryness occurs, reduce frequency to once each day.
Acne Treatment Gel
- Each night, dispense a small amount of gel onto the fingertips.
- Spread gel sparingly on the face and other affected areas using small circular motions avoiding the eyes.
- Repeat after perspiration or makeup use.
- If dryness occurs, reduce frequency to once each day.
Sensitivity Test for a New User - Acne Treatment Gel
- Apply product sparingly to one or two small affected areas during the first 3 days.
- If no discomfort occurs, follow the directions stated above.
Inactive Ingredients
Acne Treatment Wash
Purified Water, Ammonium Lauryl Sulfate, Lauramidopropyl Betaine, Propylene Glycol, Hydroxypropyl Bis-Hydroxyethyldimonium Chloride, Triethanolamine, Hydroxypropylmethylcellulose, Magnesium Sulfate, 3-iodo-2-propynylbutylcarbamate, Diazolidinyl Urea, Peppermint Oil, Methylparaben, Propylparaben.
Acne Treatment Gel
Purified Water, Alcohol, Glycerin, Xanthan Gum, Polysorbate 20, Peppermint Oil, (.Alpha.-Tocopherol Acetate), Wheat Germ Oil, Glycolic Acid, Tert-Butyl Alcohol, Brucine Sulfate.
Questions or Comments
281-835-8051
M-F 8 AM to 5 PM
Kleer-Plex Advanced Acne SystemPrincipal Display PanelNDC# 37945-876-91
KleerPlexFront.jpg
DailyMed RxNorm Mappings#
| RxCUI | RxNorm string | TTY | SPL version |
|---|---|---|---|
| 1592891 | {1 (30 ML) (salicylic acid 0.02 MG/MG Topical Gel [Kleer Plex]) / 1 (118 ML) (salicylic acid 20 MG/ML Medicated Liquid Soap [Kleer Plex]) } Pack [Kleer Plex Acne Care] | BPCK | 4 |
| 1592888 | {1 (30 ML) (salicylic acid 0.02 MG/MG Topical Gel) / 1 (118 ML) (salicylic acid 20 MG/ML Medicated Liquid Soap) } Pack | GPCK | 4 |
| 1591999 | Kleer Plex 2 % Topical Gel | PSN | 4 |
| 1592891 | Kleer Plex Acne Care Kit | PSN | 4 |
| 1591995 | Kleer-Plex 2 % Medicated Liquid Soap | PSN | 4 |
| 562600 | salicylic acid 2 % Medicated Liquid Soap | PSN | 4 |
| 1592888 | salicylic acid 2 % Medicated Liquid Soap (4 OZ) / salicylic acid 2 % Topical Gel (1 OZ) Pack | PSN | 4 |
| 346298 | salicylic acid 2 % Topical Gel | PSN | 4 |
| 1591999 | salicylic acid 0.02 MG/MG Topical Gel [Kleer Plex] | SBD | 4 |
| 1591995 | salicylic acid 20 MG/ML Medicated Liquid Soap [Kleer Plex] | SBD | 4 |
| 346298 | salicylic acid 0.02 MG/MG Topical Gel | SCD | 4 |
| 562600 | salicylic acid 20 MG/ML Medicated Liquid Soap | SCD | 4 |
| 1592891 | { 1 (15 ML) (salicylic acid 2 % Topical Gel [Kleer Plex]) / 1 (30 ML) (salicylic acid 2 % Topical Gel [Kleer Plex]) / 1 (118 ML) (salicylic acid 2 % Medicated Liquid Soap [Kleer Plex]) } Pack [Kleer Plex Acne Care Kit] | SY | 4 |
| 1591999 | Kleer Plex 0.02 MG/MG Topical Gel | SY | 4 |
| 1591995 | Kleer Plex 2 % Medicated Liquid Soap | SY | 4 |
| 1591999 | Kleer Plex 2 % Topical Gel | SY | 4 |
| 1591995 | Kleer Plex 20 MG/ML Medicated Liquid Soap | SY | 4 |
| 1592891 | Kleer Plex Acne Care Kit | SY | 4 |
| 562600 | salicylic acid 2 % Facial Cleanser Toner | SY | 4 |
| 562600 | salicylic acid 2 % Facial Scrub | SY | 4 |
| 562600 | salicylic acid 2 % Medicated Liquid Soap | SY | 4 |
| 346298 | salicylic acid 2 % Topical Gel | SY | 4 |
FDA-Initiated Inactive NDC Indexing#
| NDC | Effective | Action | Document | Indexing SPL | Related label |
|---|---|---|---|---|---|
| 37945-876-91 | 2020-01-31 | C162847 | 48780-1 | 9d75b9d0-0d87-f424-e053-dadaa90a57ce | Kleer-Plex Advanced Acne Care System |
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 37945-870-40 | Kleer-Plex Advanced Acne Care System | 1 in 1 BOX | LIQUID | 20 mg in 1mL | 4 | |
| 37945-870-40 | Kleer-Plex Advanced Acne Care System | 118 mL in 1 BOTTLE, PUMP | LIQUID | 118 mL | 20 mg in 1mL | 4 |
| 37945-874-11 | Kleer-Plex Advanced Acne Care System | 30 mL in 1 BOTTLE | GEL | 30 mL | 20 mg in 1mL | 4 |
| 37945-874-11 | Kleer-Plex Advanced Acne Care System | 1 in 1 BOX | GEL | 20 mg in 1mL | 4 | |
| 37945-876-91 | Kleer-Plex Advanced Acne Care System | 1 in 1 KIT | KIT | 1 | 4 | |
| 37945-894-05 | Kleer-Plex Advanced Acne Care System | 15 mL in 1 APPLICATOR | GEL | 15 mL | 20 mg in 1mL | 4 |
| 37945-894-05 | Kleer-Plex Advanced Acne Care System | 1 in 1 BOX | GEL | 20 mg in 1mL | 4 |
DailyMed Dashboard NDC Coverage#
| NDC | Dashboard title | SPL version | Validation | Dashboard ZIP |
|---|---|---|---|---|
| 37945-870 | KLEER-PLEX ADVANCED ACNE CARE SYSTEM (SALICYLIC ACID) KIT [BIO-MEDICAL & PHARMACEUTICAL MANUFACTURING CORPORATION] | 4 | Legacy NDC | 20141103_79f8fc90-2447-4224-ac79-1645d1c82d4f.zip |
| 37945-874 | KLEER-PLEX ADVANCED ACNE CARE SYSTEM (SALICYLIC ACID) KIT [BIO-MEDICAL & PHARMACEUTICAL MANUFACTURING CORPORATION] | 4 | Legacy NDC | 20141103_79f8fc90-2447-4224-ac79-1645d1c82d4f.zip |
| 37945-876 | KLEER-PLEX ADVANCED ACNE CARE SYSTEM (SALICYLIC ACID) KIT [BIO-MEDICAL & PHARMACEUTICAL MANUFACTURING CORPORATION] | 4 | Legacy NDC, 7 package rows | 20141103_79f8fc90-2447-4224-ac79-1645d1c82d4f.zip |
| 37945-894 | KLEER-PLEX ADVANCED ACNE CARE SYSTEM (SALICYLIC ACID) KIT [BIO-MEDICAL & PHARMACEUTICAL MANUFACTURING CORPORATION] | 4 | Legacy NDC | 20141103_79f8fc90-2447-4224-ac79-1645d1c82d4f.zip |
DailyMed Socrata Ingredients#
| Ingredient | Type | UNII | SPL version | Uploaded |
|---|---|---|---|---|
| SALICYLIC ACID | ACTIVE INGREDIENT | O414PZ4LPZ | 4 | |
| SALICYLIC ACID | ACTIVE MOIETY | O414PZ4LPZ | 4 | |
| .ALPHA.-TOCOPHEROL ACETATE | INACTIVE INGREDIENT | 9E8X80D2L0 | 4 | |
| ALCOHOL | INACTIVE INGREDIENT | 3K9958V90M | 4 | |
| AMMONIUM LAURYL SULFATE | INACTIVE INGREDIENT | Q7AO2R1M0B | 4 | |
| BRUCINE SULFATE | INACTIVE INGREDIENT | KY7O12XPOQ | 4 | |
| DIAZOLIDINYL UREA | INACTIVE INGREDIENT | H5RIZ3MPW4 | 4 | |
| GLYCERIN | INACTIVE INGREDIENT | PDC6A3C0OX | 4 | |
| GLYCOLIC ACID | INACTIVE INGREDIENT | 0WT12SX38S | 4 | |
| HYDROXYPROPYL BIS-HYDROXYETHYLDIMONIUM CHLORIDE | INACTIVE INGREDIENT | 1EO3O1X7HG | 4 | |
| HYPROMELLOSES | INACTIVE INGREDIENT | 3NXW29V3WO | 4 | |
| IODOPROPYNYL BUTYLCARBAMATE | INACTIVE INGREDIENT | 603P14DHEB | 4 | |
| LAURAMIDOPROPYL BETAINE | INACTIVE INGREDIENT | 23D6XVI233 | 4 | |
| MAGNESIUM SULFATE | INACTIVE INGREDIENT | DE08037SAB | 4 | |
| METHYLPARABEN | INACTIVE INGREDIENT | A2I8C7HI9T | 4 | |
| PEPPERMINT OIL | INACTIVE INGREDIENT | AV092KU4JH | 4 | |
| POLYSORBATE 20 | INACTIVE INGREDIENT | 7T1F30V5YH | 4 | |
| PROPYLENE GLYCOL | INACTIVE INGREDIENT | 6DC9Q167V3 | 4 | |
| PROPYLPARABEN | INACTIVE INGREDIENT | Z8IX2SC1OH | 4 | |
| TERT-BUTYL ALCOHOL | INACTIVE INGREDIENT | MD83SFE959 | 4 | |
| TROLAMINE | INACTIVE INGREDIENT | 9O3K93S3TK | 4 | |
| WATER | INACTIVE INGREDIENT | 059QF0KO0R | 4 | |
| WHEAT GERM OIL | INACTIVE INGREDIENT | 14C97E680P | 4 | |
| XANTHAN GUM | INACTIVE INGREDIENT | TTV12P4NEE | 4 |
Products#
Every source-derived product name is available through these pages.
- Kleer-Plex Advanced Acne Care System
- Salicylic Acid
- Kleer-Plex Foaming Acne Clarifier
- WATER
- AMMONIUM LAURYL SULFATE
- LAURAMIDOPROPYL BETAINE
- PROPYLENE GLYCOL
- HYDROXYPROPYL BIS-HYDROXYETHYLDIMONIUM CHLORIDE
- TROLAMINE
- HYPROMELLOSES
- MAGNESIUM SULFATE
- IODOPROPYNYL BUTYLCARBAMATE
- DIAZOLIDINYL UREA
- PEPPERMINT OIL
- METHYLPARABEN
- PROPYLPARABEN
- Kleer-Plex Pore Purifier and Toner
- WITCH HAZEL
- HORSE CHESTNUT
- WHITE OAK BARK
- ECHINACEA, UNSPECIFIED
- CHASTE TREE
- GOLDENSEAL
- ALCOHOL
- LAVENDER OIL
- POLYSORBATE 20
- ETHYL LAUROYL ARGINATE HYDROCHLORIDE
- GLYCERIN
- LEMON OIL, DISTILLED
- PHENYLETHYL ALCOHOL
- BUTYLENE GLYCOL
- 10-HYDROXYDECANOIC ACID
- SEBACIC ACID
- 1,10-DECANEDIOL
- Kleer-Plex Penetrating Acne
- XANTHAN GUM
- .ALPHA.-TOCOPHEROL ACETATE
- WHEAT GERM OIL
- GLYCOLIC ACID
- TERT-BUTYL ALCOHOL
NDC Codes#
| Product NDC | Package NDC |
|---|---|
| 37945-876 | 37945-876-91 |
| 37945-870 | 37945-870-40 |
| 37945-874 | 37945-874-11 |
| 37945-894 | 37945-894-05 |
Ingredients#
Every source-derived ingredient row is available through these pages.
Source Document#
Inactive ingredient matches#
Inactive Ingredient Database values describe FDA-listed use contexts. The match method and ambiguity count are shown because ingredient names, routes, and dosage forms are not always unique. Browse recovered IID releases and source provenance.
| DailyMed ingredient | IID ingredient | UNII | Dosage form / route | Potency | Maximum daily exposure | Match |
|---|---|---|---|---|---|---|
| METHYLPARABEN | METHYLPARABEN | A2I8C7HI9T | SHAMPOO / TOPICAL | 0.15 %w/w | ||
| HYPROMELLOSES | HYPROMELLOSE | 3NXW29V3WO | SYRUP / ORAL | 250 mg | ||
| PROPYLENE GLYCOL | PROPYLENE GLYCOL | 6DC9Q167V3 | TAMPON / VAGINAL | 62.1 mg | ||
| PROPYLENE GLYCOL | PROPYLENE GLYCOL | 6DC9Q167V3 | CAPSULE, DELAYED RELEASE / ORAL | 1.7 mg | ||
| PROPYLPARABEN | PROPYLPARABEN | Z8IX2SC1OH | AEROSOL, FOAM / TOPICAL | 0.04 %w/w | ||
| PEPPERMINT OIL | PEPPERMINT OIL | AV092KU4JH | SOLUTION / DENTAL | 0.04 %v/v | ||
| METHYLPARABEN | METHYLPARABEN | A2I8C7HI9T | FILM / BUCCAL | 1 mg | ||
| XANTHAN GUM | XANTHAN GUM | TTV12P4NEE | GRANULE, FOR SUSPENSION, EXTENDED RELEASE / ORAL | 2350 mg | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | OINTMENT / TOPICAL | NA | ||
| PROPYLENE GLYCOL | PROPYLENE GLYCOL | 6DC9Q167V3 | TABLET / ORAL | 64 mg | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | INJECTION / INTRAMUSCULAR | 450 mg | ||
| PROPYLENE GLYCOL | PROPYLENE GLYCOL | 6DC9Q167V3 | GEL / TOPICAL | 4522 mg | ||
| POLYSORBATE 20 | POLYSORBATE 20 | 7T1F30V5YH | INJECTION, SUSPENSION, EXTENDED RELEASE / INTRAMUSCULAR | 60 mg | ||
| POLYSORBATE 20 | POLYSORBATE 20 | 7T1F30V5YH | SUSPENSION / ORAL | 80 mg | ||
| PROPYLENE GLYCOL | PROPYLENE GLYCOL | 6DC9Q167V3 | SOLUTION, CONCENTRATE / INTRAVENOUS | 50.33 %w/v | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | SUSPENSION / RECTAL | 0.35 %v/v | ||
| METHYLPARABEN | METHYLPARABEN | A2I8C7HI9T | SUSPENSION, EXTENDED RELEASE / ORAL | 40 mg | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | SYSTEM / IONTOPHORESIS | 168.1 mg | ||
| XANTHAN GUM | XANTHAN GUM | TTV12P4NEE | SUSPENSION / RECTAL | 452 mg | ||
| AMMONIUM LAURYL SULFATE | AMMONIUM LAURYL SULFATE | Q7AO2R1M0B | EMULSION / TOPICAL | 39.75 %w/w | ||
| HYPROMELLOSES | HYPROMELLOSE | 3NXW29V3WO | SHAMPOO / TOPICAL | 3 %w/w | ||
| METHYLPARABEN | METHYLPARABEN | A2I8C7HI9T | TABLET, CHEWABLE / ORAL | 1.28 mg | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | TABLET, FILM COATED / ORAL | 1.55 mg | ||
| METHYLPARABEN | METHYLPARABEN | A2I8C7HI9T | INJECTION, POWDER, FOR SOLUTION / INTRAVENOUS | 15 mg | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | SOLUTION / RESPIRATORY (INHALATION) | 5 %w/w | ||
| ALCOHOL | ALCOHOL | 3K9958V90M | DROPS / ORAL | 210 mg/1ml | ||
| AMMONIUM LAURYL SULFATE | AMMONIUM LAURYL SULFATE | Q7AO2R1M0B | AEROSOL / TOPICAL | NA | ||
| PROPYLENE GLYCOL | PROPYLENE GLYCOL | 6DC9Q167V3 | INJECTION, SOLUTION / INTRAMUSCULAR | 4000 mg | ||
| PROPYLENE GLYCOL | PROPYLENE GLYCOL | 6DC9Q167V3 | SOLUTION / RESPIRATORY (INHALATION) | 25 %w/w | ||
| PROPYLPARABEN | PROPYLPARABEN | Z8IX2SC1OH | SOLUTION / TOPICAL | 24 mg | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | SOLUTION/ DROPS / AURICULAR (OTIC) | 25 mg | ||
| PROPYLPARABEN | PROPYLPARABEN | Z8IX2SC1OH | ELIXIR / ORAL | 200 mg | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | JELLY / VAGINAL | NA | ||
| METHYLPARABEN | METHYLPARABEN | A2I8C7HI9T | INJECTION / INTRAMUSCULAR | 95 mg | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | PASTE / DENTAL | 20 %w/w | ||
| METHYLPARABEN | METHYLPARABEN | A2I8C7HI9T | OINTMENT / TOPICAL | 29 mg | ||
| PROPYLENE GLYCOL | PROPYLENE GLYCOL | 6DC9Q167V3 | SPRAY, METERED / NASAL | 240 mg | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | MOUTHWASH / BUCCAL | 100 mg/1ml | ||
| PROPYLPARABEN | PROPYLPARABEN | Z8IX2SC1OH | SYSTEM / TOPICAL | 21 mg | ||
| HYPROMELLOSES | HYPROMELLOSE | 3NXW29V3WO | TABLET, ORALLY DISINTEGRATING / ORAL | 41 mg | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | CAPSULE / ORAL | 3487 mg | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | INJECTION / INTRAVENOUS | 33750 mg | ||
| PROPYLENE GLYCOL | PROPYLENE GLYCOL | 6DC9Q167V3 | CAPSULE, COATED, EXTENDED RELEASE / ORAL | NA | ||
| PROPYLENE GLYCOL | PROPYLENE GLYCOL | 6DC9Q167V3 | TABLET, FILM COATED / ORAL | 96 mg | ||
| METHYLPARABEN | METHYLPARABEN | A2I8C7HI9T | LOTION / TOPICAL | 351 mg | ||
| PROPYLPARABEN | PROPYLPARABEN | Z8IX2SC1OH | PASTE, DENTIFRICE / DENTAL | NA | ||
| DIAZOLIDINYL UREA | DIAZOLIDINYL UREA | H5RIZ3MPW4 | CREAM / TOPICAL | 29 mg | ||
| HYPROMELLOSES | HYPROMELLOSE | 3NXW29V3WO | CAPSULE, EXTENDED RELEASE / ORAL | 119.7 mg | ||
| PEPPERMINT OIL | PEPPERMINT OIL | AV092KU4JH | LOZENGE / ORAL | 12 mg | ||
| POLYSORBATE 20 | POLYSORBATE 20 | 7T1F30V5YH | SPRAY, METERED / NASAL | 40 mg | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | GEL / TRANSDERMAL | 500 mg | ||
| HYPROMELLOSES | HYPROMELLOSE | 3NXW29V3WO | TABLET, FILM COATED, EXTENDED RELEASE / ORAL | 221 mg | ||
| POLYSORBATE 20 | POLYSORBATE 20 | 7T1F30V5YH | CLOTH / TOPICAL | NA | ||
| METHYLPARABEN | METHYLPARABEN | A2I8C7HI9T | DROPS / NASAL | 26 mg | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | JELLY / TOPICAL | NA | ||
| GLYCERIN | GLYCERIN | PDC6A3C0OX | CREAM / TOPICAL | 1720 mg | ||
| METHYLPARABEN | METHYLPARABEN | A2I8C7HI9T | CREAM / VAGINAL | 22 mg | ||
| POLYSORBATE 20 | POLYSORBATE 20 | 7T1F30V5YH | SUPPOSITORY / VAGINAL | NA | ||
| PROPYLPARABEN | PROPYLPARABEN | Z8IX2SC1OH | LIQUID / ORAL | 2 mg | ||
| PROPYLPARABEN | PROPYLPARABEN | Z8IX2SC1OH | CREAM / VAGINAL | 3 mg |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| 25c82c9e-09aa-4486-8fa0-a9fb4cd494ba | 79f8fc90-2447-4224-ac79-1645d1c82d4f | 2014-11-03 | Warnings | 25c82c9e-09aa-4486-8fa0-a9fb4cd494ba 79f8fc90-2447-4224-ac79-1645d1c82d4f |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.