Drug Facts

Manufacturer
CVS Pharmacy
Effective date
2026-07-22
Label type
HUMAN OTC DRUG LABEL
Version
10
Source
daily-update
Hydrated at
2026-07-25 05:10:29

Label at a glance#

ProductDaytime Nighttime Cold Flu Relief
Active ingredientACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HYDROCHLORIDE
Label structure12 sections

Indications and uses

DAYTIME temporarily relieves common cold and flu symptoms cough due to minor throat and bronchial irritation  fever sore throat nasal congestion and sinus pressure headache minor aches and pain NIGHTTIME temporarily relieves common cold and flu symptoms cough due to minor throat and bronchial irritation sore throat headache minor aches and pains fever runny nose and sneezing

Dosage and administration

DAYTIME do not take more than directed (see Overdose warning) do not take more than 4 doses in 24 hours swallow whole; do not crush, chew, or dissolve adults and children 12 years and over; take 2 softgels with water every 4 hours. children under 12 years: do not use NIGHTTIME do not take more than directed (see Overdose warning) do not take more than 4 doses in 24 hours swallow whole; do not crush, chew, or disso...

Storage and handling

store between 15-30°C (59-86°F) avoid excessive heat

Label contents#

Full prescribing information#

Active ingredients for Daytime (in each softgel)

OTC - ACTIVE INGREDIENT SECTION

Acetaminophen 325 mg

Dextromethorphan HBr 10 mg

Phenylephrine HCl 5 mg

Active ingredients for Nighttime (in each softgel)

OTC - ACTIVE INGREDIENT SECTION

Acetaminophen 325 mg

Dextromethorphan HBr 15 mg

Doxylamine succinate 6.25 mg

Purpose for Daytime

OTC - PURPOSE SECTION

Pain reliever/fever reducer

Cough suppressant

Nasal decongestant

Purpose for Nighttime

OTC - PURPOSE SECTION

Pain reliever/fever reducer

Cough suppressant

Antihistamine

Uses

INDICATIONS & USAGE SECTION

DAYTIME

  • temporarily relieves common cold and flu symptoms
    • cough due to minor throat and bronchial irritation 
    • fever
    • sore throat
    • nasal congestion and sinus pressure
    • headache
    • minor aches and pain

NIGHTTIME

  • temporarily relieves common cold and flu symptoms
    • cough due to minor throat and bronchial irritation
    • sore throat
    • headache
    • minor aches and pains
    • fever
    • runny nose and sneezing

Warnings

WARNINGS SECTION

DAYTIME NIGHTTIME

Liver warning: These products contain acetaminophen. Severe liver damage may occur if you take:

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using these products

Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away

Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

Do not use

OTC - DO NOT USE SECTION

DAYTIME NIGHTTIME

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use if you have

OTC - ASK DOCTOR SECTION

DAYTIME

  • liver disease
  • heart disease
  • diabetes
  • thyroid disease
  • high blood pressure
  • cough that occurs with too much phlegm (mucus)
  • trouble urinating due to an enlarged prostate gland
  • persistent or chronic cough such as occurs with smoking, asthma, or emphysema

NIGHTTIME

  • liver disease
  • glaucoma
  • cough that occurs with too much phlegm (mucus)
  • a breathing problem or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema
  • trouble urinating due to an enlarged prostate gland

Ask a doctor or pharmacist before use if you are

OTC - ASK DOCTOR/PHARMACIST SECTION

DAYTIME

taking the blood thinning drug warfarin

NIGHTTIME

  • taking the blood thinning drug warfarin
  • taking sedatives or tranquilizers

When using this product,

OTC - WHEN USING SECTION

DAYTIME

do not exceed recommended dosage

NIGHTTIME

  • do not exceed recommended dosage
  • excitability may occur, especially in children
  • marked drowsiness may occur 
  • avoid alcoholic drinks
  • alcohol, sedatives, and tranquilizers may increase drowsiness
  • be careful when driving a motor vehicle or operating machinery

Stop use and ask a doctor if

OTC - STOP USE SECTION

DAYTIME

  • nervousness, dizziness or sleeplessness occur
  • pain, cough, and nasal congestion gets worse or lasts more than 7 days
  • redness or swelling is present
  • new symptoms occur
  • fever gets worse or lasts more than 3 days
  • cough comes back or occurs with rash or headache that lasts.These could be signs of a serious condition.

NIGHTTIME

  • pain or cough gets worse or lasts more than 7 days
  • fever gets worse or lasts more than 3 days
  • redness or swelling is present
  • new symptoms occur
  • cough comes back or occurs with rash headache that lasts.

These could be a signs of a serious condition.

If pregnant or breast-feeding,

OTC - PREGNANCY OR BREAST FEEDING SECTION

ask a health professional before use.

Keep out of reach of children.

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Overdose warning: Taking more than the recommended dose can cause liver damage. In case of overdose, get medical help or contact a Poison Control Center (1-800-222-1222) right away. Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Directions

DOSAGE & ADMINISTRATION SECTION

DAYTIME

  • do not take more than directed (see Overdose warning)
  • do not take more than 4 doses in 24 hours
  • swallow whole; do not crush, chew, or dissolve
  • adults and children 12 years and over; take 2 softgels with water every 4 hours.
  • children under 12 years: do not use

NIGHTTIME

  • do not take more than directed (see Overdose warning)
  • do not take more than 4 doses in 24 hours
  • swallow whole; do not crush, chew, or dissolve
  • adults and children 12 years and over: take 2 softgels with water every 6 hours
  • children under 12 years: do not use

Other information

STORAGE AND HANDLING SECTION

  • store between 15-30°C (59-86°F)
  • avoid excessive heat

Inactive ingredients

INACTIVE INGREDIENT SECTION

DAYTIME

FD&C red #40, FD&C yellow #6, gelatin, glycerin, lecithin, light mineral oil, mannitol, polyethylene glycol, povidone, propylene glycol, purified water, sorbitan, sorbitol, white ink

NIGHTTIME

D&C yellow #10, FD&C blue #1, gelatin, glycerin, lecithin, light mineral oil, mannitol, polyethylene glycol, povidone, propylene glycol, purified water, sorbitan, sorbitol, white ink

Questions or comments?

OTC - QUESTIONS SECTION

Call 1-877-753-3935 Monday-Friday 9AM-5PM EST

Principal Display Panel

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

Compare to Vicks® DayQuil™ and NyQuil™ Cold & Flu LiquiCaps™active ingredients*

DAYTIME

COLD & FLU

Acetaminophen 

Pain reliever; Fever reducer

Dextromethorphan HBr

Cough suppressant

Phenylephrine HCI Nasal decongestant

Multi-Symptom Relief

Aches, Fever, Sore throat, Cough, Nasal congestion, Sinus Pressure

SOFTGELS**

NIGHTTIME

COLD & FLU

Acetaminophen 

Pain reliever; Fever reducer

Dextromethorphan HBr

Cough suppressant

Doxylamine Succinate

Antihistamine

Multi-Symptom Relief

Aches, Fever, Sore throat, Cough, Sneezing; Runny nose

SOFTGELS**

(**Liquid filled capsules)

When using Daytime and Nighttime products, carefully read the labeling to ensure correct dosing.

*This product is not manufactured or distributed by The Procter & Gamble Company. Vicks®, DayQuil™, NyQuil™, and LiquiCaps™ are registered trademarks of the Procter and Gamble Company.

TAMPER EVIDENT: DO NOT USE IF CARTON IS OPENED OR IF BLISTER UNIT IS TORN, BROKEN OR SHOW SIGNS OF TAMPERING.

KEEP OUTER CARTON FOR COMPLETE WARNINGS AND PRODUCT INFORMATION

Distributed by: CVS Pharmacy, Inc.

One CVS Drive, Woonsocket, RI 02895

Product Label

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

CVS Daytime Nighttime Cold & Flu
CVS Daytime Nighttime Cold & Flu

Product Linked Resources#

Resource, Code type, Value table
ResourceCode typeValueEquivalent identifiersSource image
BarcodeEAN-130050428135914GTIN-13: 0050428135914
EAN-13: 0050428135914
GTIN-12: 050428135914
UPC-A: 050428135914
GTIN storage (14 digits): 00050428135914
daytime-pe-nighttime-no-pse-pe-softgels-pur-1.jpg

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
59361619-24d9-b610-eca6-5a7f25ed5e03Product name520240909
f4368033-af8c-41bf-a84b-ff77392b8522Product name120161229

FDA-Initiated Inactive NDC Indexing#

NDC, Effective, Action table
NDCEffectiveActionDocumentIndexing SPLRelated label
69842-896-242020-10-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-10-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-10-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-10-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-10-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-10-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-10-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-10-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-09-27C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-09-27C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-09-27C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-09-27C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-09-27C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-09-27C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-09-27C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-09-27C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-09-25C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-09-25C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-09-25C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-09-25C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-09-25C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-09-25C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-09-25C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-09-25C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-07-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-07-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-07-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-242020-07-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-07-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-07-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-07-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts
69842-896-482020-07-22C16284748780-1ab0e2407-26c0-f274-e053-dbdaa90a6471Drug Facts

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
69842-896-24EA - Each69842-89635176892-183c-44ac-a949-7abe23dcf01f12022-03-09

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 28 matching rows.

NDC Codes#

Product NDC, Package NDC table
Product NDCPackage NDC
69842-89669842-896-24, 69842-896-48

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 32 matching rows.

Source Document#

Source XML

Older Hydrated Versions#

Version, Effective date, Source table
VersionEffective dateSourceHydrated
92026-05-11full-release2026-06-01 01:57:05
82025-10-30monthly-update2026-06-03 17:38:59
62025-09-18full-release2026-06-01 01:14:21

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Daytime Nighttime Cold Flu ReliefACETAMINOPHEN, DEXTROMETHORPHAN HBR, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HCLCVS Pharmacydf6e522c-3e30-4aa0-8ab9-3b579c80bcad2026-07-22WarningsExact identifier
ndc (package): 69842-896-48
ndc (package): 69842-896-24
ndc (product): 69842-896
ndc11 (package): 69842089648
ndc11 (package): 69842089624
spl id: 46775ab8-8b5a-477f-81d7-819cae41dcee
spl set id: df6e522c-3e30-4aa0-8ab9-3b579c80bcad

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.