Acne Relief (Adapalene Gel 0.1%)

Manufacturer: Little Pharma, Inc.
Effective date: 2026-01-11
Label type: HUMAN OTC DRUG LABEL
Version: 3
Source: monthly-update
Hydrated at: 2026-06-03 17:52:11

Label at a glance#

ProductCurist Acne Relief

Active ingredientADAPALENE

Label structure11 sections

Storage and handling

Other information store at room temperature 68º to 77ºF protect from freezing

Contacts and useful links#

PhoneLabel contact1 (888) 721-7115

Label contents#

Full prescribing information#

SPL UNCLASSIFIED SECTION

Drug Facts

OTC - ACTIVE INGREDIENT SECTION

Active ingredient

Adapalene USP 0.1% (retinoid)*

*read consumer information leaflet

OTC - PURPOSE SECTION

Purpose

Acne treatment

INDICATIONS & USAGE SECTION

Use

for the treatment of acne

WARNINGS SECTION

Warnings

For external use only

OTC - DO NOT USE SECTION

Do not use

on damaged skin (cuts, abrasions eczema, sunburn)
if you are allergic to adapalene or any of the ingredients in this product

OTC - PREGNANCY OR BREAST FEEDING SECTION

If pregnant or breast-feeding, ask a doctor before use

OTC - WHEN USING SECTION

When using this product

limit sun exposure, including light from tanning beds, and use sunscreen when going outdoors
do not wax to remove hair in areas where the product has been applied
during the early weeks of use, your acne may appear to worsen before it improves (this is normal); continue using as directed, unless you get irritation that become severe
irritation (redness, itching, dryness, burning) is more likely to occur:
- in the first few weeks of use
- if using more than one topical acne medication at a time
- but irritation usually lessens with continued use of this product
it may take up to 3 months of once daily use to see result
avoid product contact eyes, lips, and month. If contact occurs immediately flush the area with water.
wash hands after use

OTC - STOP USE SECTION

Stop use and ask a doctor if

you become pregnant, or planning to become pregnant while using this product
you have symptoms of an allergic reaction (such as itching, rash, hives, swelling of the lips, eyelids, and shortness of breath)
irritation become severe
you see no improvement after 3 months of once daily use

OTC - KEEP OUT OF REACH OF CHILDREN SECTION

Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

DOSAGE & ADMINISTRATION SECTION

Directions

Adults and children 12 years of age and older:

use once daily
clean the skin gently and pat dry before applying the product
cover the entire affected area with a thin layer. For example, if your acne in on the face, apply the product to the entire face.
do not use more than one time a day. Applying more than directed will not provide faster or better results, but may worsen skin irritation.
Children under 12 years of age: ask a doctor

STORAGE AND HANDLING SECTION

Other information

store at room temperature 68º to 77ºF
protect from freezing

INACTIVE INGREDIENT SECTION

Inactive ingredients carbomer homopolymer, edetate disodium, methylparaben, poloxamer 182, propylene glycol, purified water and sodium hydroxide

OTC - QUESTIONS SECTION

Questions? Call 1 (888) 721-7115

SPL UNCLASSIFIED SECTION

*Read carton and enclosed consumer information leaflet before using this product. Keep this carton and consumer information leaflet.The contain important information.

Distributed by: Little Pharma, Inc.

New York, NY 10023 | Made in India

PACKAGE LABEL.PRINCIPAL DISPLAY PANEL

curist

Acne Relief

Adapalene Gel, 0.1%

Acne Teatment

Once Daily Topical Retinoid*

Fragrance Free

Oil Free

NET WT 1.6 oz (45 g)

AdapaleneGel-45G Final

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	SPL version
307731	adapalene 0.1 % Topical Gel	PSN	3
307731	adapalene 0.001 MG/MG Topical Gel	SCD	3
307731	adapalene 0.1 % Topical Gel	SY	3

DailyMed Pharmacologic Classes#

Class, Version, Type table
Class	Version	Type	Effective
ADAPALENE Pharmacologic Class Indexing	2	Indexing - Pharmacologic Class	20180813

Product Linked Resources#

Resource, Code type, Value table
Resource	Code type	Value	Equivalent identifiers	Source image
Barcode	EAN-13	0372559015133	GTIN-13: 0372559015133 EAN-13: 0372559015133 GTIN-12: 372559015133 UPC-A: 372559015133 GTIN storage (14 digits): 00372559015133	AdapaleneGel-45G Final.jpg

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
a46239a7-5963-4008-8cbb-6b9000f497eb	Product name	1	20250721
d9d61457-6a5a-41fc-b418-e5479a2904b7	Product name	2	20230303
91d0a1ed-5d14-5017-c7aa-3602ee038695	Product name	3	20210111
3f45980c-c196-47e5-0e5e-48b7c57327c5	Product name	5	20200428
5c3dfd42-8936-4261-a420-cfcbbf3030aa	Product name	2	20161206
08f39758-2d46-8afe-73ca-39fe69052a2b	Product name	1	20140508
8ae7bcde-1dd2-b073-852b-f464987f7427	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
72559-015-13	Curist Acne Relief	45 g in 1 TUBE	GEL	45	3
72559-015-13	Curist Acne Relief	1 in 1 CARTON	GEL	1	3
72559-015-17	Curist Acne Relief	2 in 1 PACKAGE, COMBINATION	GEL	2	3
72559-015-17	Curist Acne Relief	1 in 1 CARTON	GEL	1	3

Products#

Every source-derived product name is available through these pages.

DailyMed product names page 1 of 1 · 9 matching rows.

Curist Acne Relief
Adapalene
CARBOMER HOMOPOLYMER TYPE C (ALLYL PENTAERYTHRITOL CROSSLINKED)
EDETATE DISODIUM
METHYLPARABEN
POLOXAMER 182
PROPYLENE GLYCOL
WATER
SODIUM HYDROXIDE

NDC Codes#

Product NDC, Package NDC table
Product NDC	Package NDC
72559-015	72559-015-13, 72559-015-17

Ingredients#

Every source-derived ingredient row is available through these pages.

DailyMed ingredient rows page 1 of 1 · 8 matching rows.

Name, UNII, Kind table
Name	UNII	Kind
CARBOMER HOMOPOLYMER TYPE C (ALLYL PENTAERYTHRITOL CROSSLINKED)	4Q93RCW27E	IACT
EDETATE DISODIUM	7FLD91C86K	IACT
METHYLPARABEN	A2I8C7HI9T	IACT
POLOXAMER 182	JX0HIX6OAG	IACT
PROPYLENE GLYCOL	6DC9Q167V3	IACT
WATER	059QF0KO0R	IACT
SODIUM HYDROXIDE	55X04QC32I	IACT
ADAPALENE	1L4806J2QF	ACTIB

Source Document#

Source XML

Older Hydrated Versions#

Version, Effective date, Source table
Version	Effective date	Source	Hydrated
2	2024-06-21	full-release	2026-06-01 00:34:34

Orange Book application contexts#

All distinct exact application/product contexts derived from this label’s complete NDC list are paginated below.

Orange Book application contexts page 1 of 1 · 1 matching rows.

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	RLD / RS	Approval date
A091314-001	ADAPALENE	ADAPALENE	0.1%	GEL / TOPICAL			2010-07-01

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 46 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	Approval date	Source SHA-256
2026-09-14 22:38:34	2026-08	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`301d65b070ca…`
2024-06-18 03:08 UTC · 5 captures of this ZIP	2024-06	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`1e350fbaab3a…`
2024-05-31 18:47 UTC	2024-05	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`8072bd15b7f6…`
2022-06-29 02:47 UTC · 2 captures of this ZIP	2022-06	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`5c6f7cd8ea54…`
2022-04-08 23:34 UTC	2022-04	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`5d02ea3f76ae…`
2022-04-04 05:41 UTC	2022-04	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`4b0b4de00fa7…`
2019-12-13 00:20 UTC	2019-12	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL	AB	2010-07-01	`74a2ff9319b5…`
2019-12-13 00:20 UTC	2019-12	A091314-002	ADAPALENE	0.1%	GEL / TOPICAL		2019-07-09	`74a2ff9319b5…`
2022-03-09 01:35 UTC	2022-03	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`bb7c543d1eb4…`
2021-12-28 21:50 UTC	2021-12	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`782e0a99824c…`
2021-05-05 16:15 UTC · 3 captures of this ZIP	2021-05	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`87673890dc5c…`
2021-03-12 10:30 UTC	2021-03	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`5aa47cf7b7d7…`
2020-12-22 03:56 UTC	2020-12	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`8869cabd3fbd…`
2020-11-12 02:37 UTC	2020-11	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`c0c555d07b60…`
2019-12-14 00:12 UTC	2019-12	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL	AB	2010-07-01	`3f01610625f2…`
2019-12-14 00:12 UTC	2019-12	A091314-002	ADAPALENE	0.1%	GEL / TOPICAL		2019-07-09	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL	AB	2010-07-01	`b00525d2431f…`
2019-09-15 20:21 UTC	2019-09	A091314-002	ADAPALENE	0.1%	GEL / TOPICAL		2019-07-09	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL	AB	2010-07-01	`ea99ee380514…`
2024-03-16 18:09 UTC · 4 captures of this ZIP	2024-03	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`6a51e52b5d6a…`
2024-02-18 07:12 UTC	2024-02	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`1c564ffb4f44…`
2023-12-20 04:57 UTC	2023-12	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`ea1830bbd6c7…`
2023-11-28 05:40 UTC · 2 captures of this ZIP	2023-11	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`a72a2bbeb626…`
2023-10-25 00:34 UTC · 2 captures of this ZIP	2023-10	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`9b2671bbb829…`
2023-07-15 15:27 UTC · 2 captures of this ZIP	2023-07	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`a67488948f0b…`
2023-06-13 01:57 UTC · 3 captures of this ZIP	2023-06	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`3f0d92c62455…`
2023-05-13 08:27 UTC	2023-05	A091314-001	ADAPALENE	0.1%	GEL / TOPICAL		2010-07-01	`053a50430f4f…`

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2019-12-13 00:20 UTC	2019-12	A091314-001	AB	1	`74a2ff9319b5…`
2019-12-14 00:12 UTC	2019-12	A091314-001	AB	1	`3f01610625f2…`
2019-09-15 20:21 UTC	2019-09	A091314-001	AB	1	`b00525d2431f…`
2019-07-19 19:46 UTC	2019-07	A091314-001	AB	1	`ea99ee380514…`

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Curist Acne Relief	ADAPALENE	Little Pharma, Inc.	e6380880-5299-0826-e053-2a95a90a1942	2026-01-11	Warnings	Exact identifier ndc (package): 72559-015-17 ndc (package): 72559-015-13 ndc (product): 72559-015 ndc11 (package): 72559001513 ndc11 (package): 72559001517 spl id: 4821e693-2293-b60e-e063-6294a90a7d86 spl set id: e6380880-5299-0826-e053-2a95a90a1942

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.