FDA.reportPublic FDA data

ADAPALENE

Substance profile for UNII 1L4806J2QF, enriched with FDA NDC listings, DailyMed labels, legacy aliases, and open chemistry identifiers.

Chemical structure for ADAPALENE
Structure render from PubChem CID 60164

Substance Identity#

UNII
1L4806J2QF
Preferred term
ADAPALENE
Registry number
106685-40-9
Ingredient type
INGREDIENT SUBSTANCE
Molecular formula
C28H28O3
Chemical structure for ADAPALENE
Structure render from PubChem CID 60164

Chemical And Database Identifiers#

InChIKey
LZCDAPDGXCYOEH-UHFFFAOYSA-N
SMILES
COC1=C(C=C(C=C1)C2=CC=C3C=C(C=CC3=C2)C(O)=O)C45CC6CC(CC(C6)C4)C5
RxCUI
60223
PubChem
60164
NCIt
C28989
INN ID
6675

Open Chemistry Sources#

Source, Identifier, Link table
SourceIdentifierLink
PubChem Compound60164https://pubchem.ncbi.nlm.nih.gov/compound/60164
PubChem InChIKey SearchLZCDAPDGXCYOEH-UHFFFAOYSA-Nhttps://pubchem.ncbi.nlm.nih.gov/#query=LZCDAPDGXCYOEH-UHFFFAOYSA-N
RxNorm60223https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=60223
NCI ThesaurusC28989https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C28989
FDA Substance Registration System1L4806J2QFhttps://precision.fda.gov/uniisearch/srs/unii/1L4806J2QF

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
ADAPALENEACTIVE MOIETY1L4806J2QFThese highlights do not include all the information needed to use DIFFERIN safely and effectively. See full prescribing information for DIFFERIN (adapalene) Gel, 0.3% DIFFERIN (adapalene) Gel, 0.3% For topical use only Initial U.S. Approval: 19962
AdapaleneACTIVE INGREDIENT1L4806J2QFThese highlights do not include all the information needed to use DIFFERIN safely and effectively. See full prescribing information for DIFFERIN (adapalene) Gel, 0.3% DIFFERIN (adapalene) Gel, 0.3% For topical use only Initial U.S. Approval: 19962
adapaleneACTIVE MOIETY1L4806J2QFDIFFERIN ® (adapalene gel) Gel, 0.1% Rx Only2
adapaleneACTIVE INGREDIENT1L4806J2QFDIFFERIN ® (adapalene gel) Gel, 0.1% Rx Only2
AdapaleneACTIVE MOIETY1L4806J2QFThese highlights do not include all the information needed to use DIFFERIN safely and effectively. See full prescribing information for DIFFERIN Lotion. DIFFERIN® (adapalene) Lotion 0.1% For topical use only Initial U.S. Approval: 19962
AdapaleneACTIVE INGREDIENT1L4806J2QFThese highlights do not include all the information needed to use DIFFERIN safely and effectively. See full prescribing information for DIFFERIN Lotion. DIFFERIN® (adapalene) Lotion 0.1% For topical use only Initial U.S. Approval: 19962
ADAPALENEACTIVE MOIETY1L4806J2QFThese highlights do not include all the information needed to use EPIDUO Gel safely and effectively. See full prescribing information for EPIDUO Gel. EPIDUO (adapalene and benzoyl peroxide) Gel 0.1%/2.5% For topical use Initial U.S. Approval: 20082
ADAPALENEACTIVE INGREDIENT1L4806J2QFThese highlights do not include all the information needed to use EPIDUO Gel safely and effectively. See full prescribing information for EPIDUO Gel. EPIDUO (adapalene and benzoyl peroxide) Gel 0.1%/2.5% For topical use Initial U.S. Approval: 20082
ADAPALENEACTIVE MOIETY1L4806J2QFfb57f9d4-54d6-412c-aeb4-00a8bd46f9581
ADAPALENEACTIVE INGREDIENT1L4806J2QFfb57f9d4-54d6-412c-aeb4-00a8bd46f9581
ADAPALENEACTIVE INGREDIENT1L4806J2QFADAPALENE GEL, 0.1%1
ADAPALENEACTIVE MOIETY1L4806J2QFADAPALENE GEL, 0.1%1
ADAPALENEACTIVE INGREDIENT1L4806J2QFAdapalene Cream, 0.1%1
ADAPALENEACTIVE MOIETY1L4806J2QFAdapalene Cream, 0.1%1
ADAPALENEACTIVE INGREDIENT1L4806J2QFEPIDUO (ADAPALENE AND BENZOYL PEROXIDE) GEL [GALDERMA LABORATORIES, L.P.]9
ADAPALENEACTIVE MOIETY1L4806J2QFEPIDUO (ADAPALENE AND BENZOYL PEROXIDE) GEL [GALDERMA LABORATORIES, L.P.]9
ADAPALENEACTIVE INGREDIENT1L4806J2QFADAPALENE GEL [GLENMARK PHARMACEUTICALS INC., USA]8
ADAPALENEACTIVE MOIETY1L4806J2QFADAPALENE GEL [GLENMARK PHARMACEUTICALS INC., USA]8
ADAPALENEACTIVE MOIETY1L4806J2QFDIFFERIN (ADAPALENE) GEL [GALDERMA LABORATORIES, L.P.]8
AdapaleneACTIVE INGREDIENT1L4806J2QFDIFFERIN (ADAPALENE) GEL [GALDERMA LABORATORIES, L.P.]8
AdapaleneACTIVE INGREDIENT1L4806J2QFDIFFERIN (ADAPALENE) LOTION [GALDERMA LABORATORIES, L.P.]8
AdapaleneACTIVE MOIETY1L4806J2QFDIFFERIN (ADAPALENE) LOTION [GALDERMA LABORATORIES, L.P.]8
ADAPALENEACTIVE INGREDIENT1L4806J2QFADAPALENE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]6
ADAPALENEACTIVE MOIETY1L4806J2QFADAPALENE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]6
ADAPALENEACTIVE INGREDIENT1L4806J2QFDIFFERIN (ADAPALENE) GEL [GALDERMA LABORATORIES, L.P.]4
ADAPALENEACTIVE MOIETY1L4806J2QFDIFFERIN (ADAPALENE) GEL [GALDERMA LABORATORIES, L.P.]4
AdapaleneACTIVE INGREDIENT1L4806J2QFADAPALENE GEL [TARO PHARMACEUTICALS U.S.A., INC.]3
AdapaleneACTIVE MOIETY1L4806J2QFADAPALENE GEL [TARO PHARMACEUTICALS U.S.A., INC.]3
AdapaleneACTIVE MOIETY1L4806J2QFDIFFERIN (ADAPALENE) CREAM [GALDERMA LABORATORIES, L.P]3
AdapaleneACTIVE INGREDIENT1L4806J2QFDIFFERIN (ADAPALENE) CREAM [GALDERMA LABORATORIES, L.P]3
ADAPALENEACTIVE MOIETY1L4806J2QFEPIDUO FORTE (ADAPALENE AND BENZOYL PEROXIDE) GEL [GALDERMA LABORATORIES, L.P.]3
ADAPALENEACTIVE INGREDIENT1L4806J2QFEPIDUO FORTE (ADAPALENE AND BENZOYL PEROXIDE) GEL [GALDERMA LABORATORIES, L.P.]3
ADAPALENEACTIVE MOIETY1L4806J2QFADAPALENE CREAM [PERRIGO NEW YORK INC]2
ADAPALENEACTIVE INGREDIENT1L4806J2QFADAPALENE CREAM [PERRIGO NEW YORK INC]2
ADAPALENEACTIVE MOIETY1L4806J2QFADAPALENE GEL [ACTAVIS PHARMA, INC.]2
ADAPALENEACTIVE INGREDIENT1L4806J2QFADAPALENE GEL [ACTAVIS PHARMA, INC.]2
ADAPALENEACTIVE MOIETY1L4806J2QFADAPALENE GEL [OWEN LABORATORIES, INC.]2
ADAPALENEACTIVE INGREDIENT1L4806J2QFADAPALENE GEL [OWEN LABORATORIES, INC.]2
ADAPALENEACTIVE MOIETY1L4806J2QFADAPALENE GEL [TEVA PHARMACEUTICALS USA INC]2
ADAPALENEACTIVE INGREDIENT1L4806J2QFADAPALENE GEL [TEVA PHARMACEUTICALS USA INC]2
AdapaleneACTIVE INGREDIENT1L4806J2QFADAPALENE GEL [PRASCO LABORATORIES]1
ADAPALENEACTIVE MOIETY1L4806J2QFADAPALENE GEL [PRASCO LABORATORIES]1
ADAPALENEACTIVE INGREDIENT1L4806J2QFADAPALENE GEL [SANDOZ INC.]1
ADAPALENEACTIVE MOIETY1L4806J2QFADAPALENE GEL [SANDOZ INC.]1
ADAPALENEACTIVE INGREDIENT1L4806J2QFADAPALENE LOTION [OWEN LABORATORIES, INC.]1
ADAPALENEACTIVE MOIETY1L4806J2QFADAPALENE LOTION [OWEN LABORATORIES, INC.]1