FDA.reportPublic FDA data

ADAPALENE

Substance profile for UNII 1L4806J2QF, enriched with FDA NDC listings, DailyMed labels, legacy aliases, and open chemistry identifiers.

Chemical structure for ADAPALENE
Structure render from PubChem CID 60164

Substance Identity#

UNII
1L4806J2QF
Preferred term
ADAPALENE
Registry number
106685-40-9
Ingredient type
INGREDIENT SUBSTANCE
Molecular formula
C28H28O3
Chemical structure for ADAPALENE
Structure render from PubChem CID 60164

Chemical And Database Identifiers#

InChIKey
LZCDAPDGXCYOEH-UHFFFAOYSA-N
SMILES
COC1=C(C=C(C=C1)C2=CC=C3C=C(C=CC3=C2)C(O)=O)C45CC6CC(CC(C6)C4)C5
RxCUI
60223
PubChem
60164
NCIt
C28989
INN ID
6675

Open Chemistry Sources#

Source, Identifier, Link table
SourceIdentifierLink
PubChem Compound60164pubchem.ncbi.nlm.nih.gov/compound/60164
PubChem InChIKey SearchLZCDAPDGXCYOEH-UHFFFAOYSA-Npubchem.ncbi.nlm.nih.gov/#query=LZCDAPDGXCYOEH-UHFFFAOYSA-N
RxNorm60223mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=60223
NCI ThesaurusC28989ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C28989
FDA Substance Registration System1L4806J2QFprecision.fda.gov/uniisearch/srs/unii/1L4806J2QF

DailyMed Socrata Ingredients#

Type, DailyMed label, SPL version table
TypeDailyMed labelSPL version
ACTIVE INGREDIENTAdapalene Gel, 0.1%3
ACTIVE MOIETYAdapalene Gel, 0.1%3
ACTIVE INGREDIENTThese highlights do not include all the information needed to use DIFFERIN safely and effectively. See full prescribing information for DIFFERIN (adapalene) Gel, 0.3% DIFFERIN (adapalene) Gel, 0.3% For topical use only Initial U.S. Approval: 19962
ACTIVE INGREDIENTDIFFERIN ® (adapalene gel) Gel, 0.1% Rx Only2
ACTIVE MOIETYDIFFERIN ® (adapalene gel) Gel, 0.1% Rx Only2
ACTIVE MOIETYThese highlights do not include all the information needed to use DIFFERIN safely and effectively. See full prescribing information for DIFFERIN (adapalene) Gel, 0.3% DIFFERIN (adapalene) Gel, 0.3% For topical use only Initial U.S. Approval: 19962
ACTIVE MOIETYThese highlights do not include all the information needed to use DIFFERIN safely and effectively. See full prescribing information for DIFFERIN Lotion. DIFFERIN® (adapalene) Lotion 0.1% For topical use only Initial U.S. Approval: 19962
ACTIVE INGREDIENTThese highlights do not include all the information needed to use DIFFERIN safely and effectively. See full prescribing information for DIFFERIN Lotion. DIFFERIN® (adapalene) Lotion 0.1% For topical use only Initial U.S. Approval: 19962
ACTIVE MOIETYThese highlights do not include all the information needed to use EPIDUO Gel safely and effectively. See full prescribing information for EPIDUO Gel. EPIDUO (adapalene and benzoyl peroxide) Gel 0.1%/2.5% For topical use Initial U.S. Approval: 20082
ACTIVE INGREDIENTThese highlights do not include all the information needed to use EPIDUO Gel safely and effectively. See full prescribing information for EPIDUO Gel. EPIDUO (adapalene and benzoyl peroxide) Gel 0.1%/2.5% For topical use Initial U.S. Approval: 20082
ACTIVE INGREDIENTfb57f9d4-54d6-412c-aeb4-00a8bd46f9581
ACTIVE MOIETYfb57f9d4-54d6-412c-aeb4-00a8bd46f9581
ACTIVE MOIETYADAPALENE GEL, 0.1%1
ACTIVE INGREDIENTADAPALENE GEL, 0.1%1
ACTIVE MOIETYAdapalene Cream, 0.1%1
ACTIVE INGREDIENTAdapalene Cream, 0.1%1
ACTIVE INGREDIENTEPIDUO (ADAPALENE AND BENZOYL PEROXIDE) GEL [GALDERMA LABORATORIES, L.P.]9
ACTIVE MOIETYEPIDUO (ADAPALENE AND BENZOYL PEROXIDE) GEL [GALDERMA LABORATORIES, L.P.]9
ACTIVE MOIETYADAPALENE GEL [GLENMARK PHARMACEUTICALS INC., USA]8
ACTIVE INGREDIENTADAPALENE GEL [GLENMARK PHARMACEUTICALS INC., USA]8
ACTIVE MOIETYDIFFERIN (ADAPALENE) GEL [GALDERMA LABORATORIES, L.P.]8
ACTIVE INGREDIENTDIFFERIN (ADAPALENE) GEL [GALDERMA LABORATORIES, L.P.]8
ACTIVE INGREDIENTDIFFERIN (ADAPALENE) LOTION [GALDERMA LABORATORIES, L.P.]8
ACTIVE MOIETYDIFFERIN (ADAPALENE) LOTION [GALDERMA LABORATORIES, L.P.]8
ACTIVE MOIETYADAPALENE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]6
ACTIVE INGREDIENTADAPALENE CREAM [E. FOUGERA & CO. A DIVISION OF FOUGERA PHARMACEUTICALS INC.]6
ACTIVE INGREDIENTDIFFERIN (ADAPALENE) GEL [GALDERMA LABORATORIES, L.P.]4
ACTIVE MOIETYDIFFERIN (ADAPALENE) GEL [GALDERMA LABORATORIES, L.P.]4
ACTIVE MOIETYDIFFERIN (ADAPALENE) CREAM [GALDERMA LABORATORIES, L.P]3
ACTIVE INGREDIENTDIFFERIN (ADAPALENE) CREAM [GALDERMA LABORATORIES, L.P]3
ACTIVE MOIETYEPIDUO FORTE (ADAPALENE AND BENZOYL PEROXIDE) GEL [GALDERMA LABORATORIES, L.P.]3
ACTIVE INGREDIENTEPIDUO FORTE (ADAPALENE AND BENZOYL PEROXIDE) GEL [GALDERMA LABORATORIES, L.P.]3
ACTIVE INGREDIENTADAPALENE CREAM [PERRIGO NEW YORK INC]2
ACTIVE MOIETYADAPALENE CREAM [PERRIGO NEW YORK INC]2
ACTIVE INGREDIENTADAPALENE GEL [ACTAVIS PHARMA, INC.]2
ACTIVE MOIETYADAPALENE GEL [ACTAVIS PHARMA, INC.]2
ACTIVE INGREDIENTADAPALENE GEL [OWEN LABORATORIES, INC.]2
ACTIVE MOIETYADAPALENE GEL [OWEN LABORATORIES, INC.]2
ACTIVE MOIETYADAPALENE GEL [TEVA PHARMACEUTICALS USA INC]2
ACTIVE INGREDIENTADAPALENE GEL [TEVA PHARMACEUTICALS USA INC]2
ACTIVE INGREDIENTADAPALENE GEL [PRASCO LABORATORIES]1
ACTIVE MOIETYADAPALENE GEL [PRASCO LABORATORIES]1
ACTIVE INGREDIENTADAPALENE GEL [SANDOZ INC.]1
ACTIVE MOIETYADAPALENE GEL [SANDOZ INC.]1
ACTIVE INGREDIENTADAPALENE LOTION [OWEN LABORATORIES, INC.]1
ACTIVE MOIETYADAPALENE LOTION [OWEN LABORATORIES, INC.]1