adapalene

Product NDC
0472-0126
11-digit product format
004720126
Labeler code
0472
Product ID
0472-0126_9bada4fd-f276-4355-bed1-ae5eee087c95
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
adapalene
Dosage form
GEL
Route
TOPICAL
Labeler
Actavis Pharma, Inc.
Application
ANDA201000
Marketing category
ANDA
Marketing start
2014-10-27
Substance
ADAPALENE
Active strength
3 mg/g
Pharmacologic classes
Retinoid [EPC], Retinoids [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A201000-001ADAPALENEADAPALENE0.3%GEL / TOPICALAB2014-10-27

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A201000-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-2731067a03dcf5…
2025-08-23 18:47 UTC2025-08A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-276a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-2703ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-272680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-275bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-2779d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-271e350fbaab3a…
2024-05-31 18:47 UTC2024-05A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-278072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-275c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-275d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-274b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-2774a2ff9319b5…
2022-03-09 01:35 UTC2022-03A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-2787673890dc5c…
2021-03-12 10:30 UTC2021-03A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-275aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-278869cabd3fbd…
2020-11-12 02:37 UTC2020-11A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27c0c555d07b60…
2019-12-14 00:12 UTC2019-12A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-273f01610625f2…
2019-09-15 20:21 UTC2019-09A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27b00525d2431f…
2019-07-19 19:46 UTC2019-07A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-276a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-271c564ffb4f44…
2023-12-20 04:57 UTC2023-12A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-279b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-273f0d92c62455…
2023-05-13 08:27 UTC2023-05A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27053a50430f4f…
2023-01-26 05:58 UTC2023-01A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-273bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-273a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A201000-001ADAPALENE0.3%GEL / TOPICALAB2014-10-27cb3db0bc1861…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A201000-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A201000-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A201000-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A201000-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A201000-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A201000-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A201000-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A201000-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A201000-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A201000-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A201000-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A201000-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A201000-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A201000-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A201000-001AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A201000-001AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A201000-001AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A201000-001AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A201000-001AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A201000-001AB1782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A201000-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A201000-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A201000-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A201000-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A201000-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A201000-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A201000-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A201000-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A201000-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A201000-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A201000-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A201000-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A201000-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A201000-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A201000-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A201000-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A201000-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A201000-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A201000-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A201000-001AB1cb3db0bc1861…

Additional Listing Data#

Finished product
Yes
Brand name base
adapalene
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ADAPALENE3 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1L4806J2QFInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
722111Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
aacd5ec4-e2fa-460e-aaae-a0aba5c052e5Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
a46239a7-5963-4008-8cbb-6b9000f497ebProduct name120250721
d9d61457-6a5a-41fc-b418-e5479a2904b7Product name220230303
91d0a1ed-5d14-5017-c7aa-3602ee038695Product name320210111
3f45980c-c196-47e5-0e5e-48b7c57327c5Product name520200428
5c3dfd42-8936-4261-a420-cfcbbf3030aaProduct name220161206
08f39758-2d46-8afe-73ca-39fe69052a2bProduct name120140508
8ae7bcde-1dd2-b073-852b-f464987f7427Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0472-0126-45adapalene45 g in 1 TUBEGEL458
0472-0126-45adapalene1 in 1 CARTONGEL18

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0472-0126-45GM - Gram0472-012697550b89-74b8-406e-bcb8-d7fee45f779912014-11-05

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
ADAPALENEACTIVE INGREDIENT1L4806J2QFADAPALENE GEL [ACTAVIS PHARMA, INC.]2
ADAPALENEACTIVE MOIETY1L4806J2QFADAPALENE GEL [ACTAVIS PHARMA, INC.]2
CARBOMER HOMOPOLYMER TYPE C (ALLYL PENTAERYTHRITOL CROSSLINKED)INACTIVE INGREDIENT4Q93RCW27EADAPALENE GEL [ACTAVIS PHARMA, INC.]2
EDETATE SODIUMINACTIVE INGREDIENTMP1J8420LUADAPALENE GEL [ACTAVIS PHARMA, INC.]2
HYDROCHLORIC ACIDINACTIVE INGREDIENTQTT17582CBADAPALENE GEL [ACTAVIS PHARMA, INC.]2
METHYLPARABENINACTIVE INGREDIENTA2I8C7HI9TADAPALENE GEL [ACTAVIS PHARMA, INC.]2
POLOXAMER 182INACTIVE INGREDIENTJX0HIX6OAGADAPALENE GEL [ACTAVIS PHARMA, INC.]2
PROPYLENE GLYCOLINACTIVE INGREDIENT6DC9Q167V3ADAPALENE GEL [ACTAVIS PHARMA, INC.]2
SODIUM HYDROXIDEINACTIVE INGREDIENT55X04QC32IADAPALENE GEL [ACTAVIS PHARMA, INC.]2
WATERINACTIVE INGREDIENT059QF0KO0RADAPALENE GEL [ACTAVIS PHARMA, INC.]2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0472-0126ADAPALENE GEL [ACTAVIS PHARMA, INC.]8Current NDC, Legacy NDC, 2 package rows20240617_aacd5ec4-e2fa-460e-aaae-a0aba5c052e5.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
adapaleneADAPALENEActavis Pharma, Inc.aacd5ec4-e2fa-460e-aaae-a0aba5c052e52024-05-30Warnings, Adverse reactionsExact identifier
application applno (ANDA): 201000
application number: ANDA201000
ndc (product): 0472-0126

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
722111adapalene 0.3 % Topical GelPSNaacd5ec4-e2fa-460e-aaae-a0aba5c052e58
722111adapalene 0.003 MG/MG Topical GelSCDaacd5ec4-e2fa-460e-aaae-a0aba5c052e58
722111adapalene 0.3 % Topical GelSYaacd5ec4-e2fa-460e-aaae-a0aba5c052e58

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0472-0126-45004720126451 TUBE in 1 CARTON (0472-0126-45) / 45 g in 1 TUBE1 tube2014-10-270000-00-00NoNoCurrent