Home NDC 11410-956 Proactiv MD Adapalene
Product NDC 11410-956
11-digit product format 114100956
Labeler code 11410
Product ID 11410-956_f1364b67-9750-4d0d-bc59-8b100c462376
Type HUMAN OTC DRUG
Nonproprietary name Adapalene
Dosage form GEL
Route TOPICAL
Labeler Alchemee, LLC
Application NDA020380
Marketing category NDA AUTHORIZED GENERIC
Marketing start 2017-03-27
Marketing end 0000-00-00
Substance ADAPALENE
Active strength 0 g/100g
Pharmacologic classes Retinoid [EPC], Retinoids [CS]
NDC exclude flag No
Listing certified through 2023-12-31
Current FDA listing Historical FDA.report record Observed NDC auxiliary status history# This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.
Historic NDC status page 1 of 1 · 36 matching rows.
View current auxiliary records. · View the auxiliary file history.
Captured / source date, Dataset, Scope table Captured / source date Dataset Scope Package NDC Code Status Snapshot Source SHA-256 2025-12-14 17:58 UTC · source 2025-12-05 excluded product product D Discontinued by firm d630ba8d3edf…732f749b63fb…2025-12-14 17:58 UTC · source 2025-12-05 excluded package package 11410-956-17 D Discontinued by firm d630ba8d3edf…732f749b63fb…2025-12-14 17:58 UTC · source 2025-12-05 excluded package package 11410-956-38 D Discontinued by firm d630ba8d3edf…732f749b63fb…2025-12-14 17:58 UTC · source 2025-12-05 excluded package package 11410-956-44 D Discontinued by firm d630ba8d3edf…732f749b63fb…2025-08-27 00:01 UTC · source 2025-08-26 excluded product product D Discontinued by firm f5e01cc5f278…a2eaf40c39c3…2025-08-27 00:01 UTC · source 2025-08-26 excluded package package 11410-956-17 D Discontinued by firm f5e01cc5f278…a2eaf40c39c3…2025-08-27 00:01 UTC · source 2025-08-26 excluded package package 11410-956-38 D Discontinued by firm f5e01cc5f278…a2eaf40c39c3…2025-08-27 00:01 UTC · source 2025-08-26 excluded package package 11410-956-44 D Discontinued by firm f5e01cc5f278…a2eaf40c39c3…2025-04-01 02:39 UTC · source 2025-03-31 excluded product product I Inactivated by FDA 2ef7874e63bc…57b86245f4fa…2025-04-01 02:39 UTC · source 2025-03-31 excluded package package 11410-956-17 I Inactivated by FDA 2ef7874e63bc…57b86245f4fa…2025-04-01 02:39 UTC · source 2025-03-31 excluded package package 11410-956-38 I Inactivated by FDA 2ef7874e63bc…57b86245f4fa…2025-04-01 02:39 UTC · source 2025-03-31 excluded package package 11410-956-44 I Inactivated by FDA 2ef7874e63bc…57b86245f4fa…2025-03-28 20:22 UTC · source 2025-03-28 excluded product product I Inactivated by FDA a1b67e2a42f9…c4cf2c586c0d…2025-03-28 20:22 UTC · source 2025-03-28 excluded package package 11410-956-17 I Inactivated by FDA a1b67e2a42f9…c4cf2c586c0d…2025-03-28 20:22 UTC · source 2025-03-28 excluded package package 11410-956-38 I Inactivated by FDA a1b67e2a42f9…c4cf2c586c0d…2025-03-28 20:22 UTC · source 2025-03-28 excluded package package 11410-956-44 I Inactivated by FDA a1b67e2a42f9…c4cf2c586c0d…2025-03-22 03:12 UTC · source 2025-03-21 excluded product product I Inactivated by FDA cfe11265f3b6…090c488252e2…2025-03-22 03:12 UTC · source 2025-03-21 excluded package package 11410-956-17 I Inactivated by FDA cfe11265f3b6…090c488252e2…2025-03-22 03:12 UTC · source 2025-03-21 excluded package package 11410-956-38 I Inactivated by FDA cfe11265f3b6…090c488252e2…2025-03-22 03:12 UTC · source 2025-03-21 excluded package package 11410-956-44 I Inactivated by FDA cfe11265f3b6…090c488252e2…2025-03-10 12:48 UTC · source 2025-03-10 excluded product product I Inactivated by FDA cdf11ea48f46…ba0047e9e063…2025-03-10 12:48 UTC · source 2025-03-10 excluded package package 11410-956-17 I Inactivated by FDA cdf11ea48f46…ba0047e9e063…2025-03-10 12:48 UTC · source 2025-03-10 excluded package package 11410-956-38 I Inactivated by FDA cdf11ea48f46…ba0047e9e063…2025-03-10 12:48 UTC · source 2025-03-10 excluded package package 11410-956-44 I Inactivated by FDA cdf11ea48f46…ba0047e9e063…2025-02-02 03:52 UTC · source 2025-01-31 excluded product product U Excluded because listing certification expired 302b2466d912…e7b80fea0513…2025-02-02 03:52 UTC · source 2025-01-31 excluded package package 11410-956-38 U Excluded because listing certification expired 302b2466d912…e7b80fea0513…2025-02-02 03:52 UTC · source 2025-01-31 excluded package package 11410-956-17 U Excluded because listing certification expired 302b2466d912…e7b80fea0513…2025-02-02 03:52 UTC · source 2025-01-31 excluded package package 11410-956-44 U Excluded because listing certification expired 302b2466d912…e7b80fea0513…2025-01-20 13:05 UTC · source 2025-01-20 excluded product product U Excluded because listing certification expired ed331223b511…672a5bd82f5f…2025-01-20 13:05 UTC · source 2025-01-20 excluded package package 11410-956-38 U Excluded because listing certification expired ed331223b511…672a5bd82f5f…2025-01-20 13:05 UTC · source 2025-01-20 excluded package package 11410-956-17 U Excluded because listing certification expired ed331223b511…672a5bd82f5f…2025-01-20 13:05 UTC · source 2025-01-20 excluded package package 11410-956-44 U Excluded because listing certification expired ed331223b511…672a5bd82f5f…2025-01-11 03:41 UTC · source 2025-01-10 excluded product product U Excluded because listing certification expired 0efc9e666f02…f202fb6c5f17…2025-01-11 03:41 UTC · source 2025-01-10 excluded package package 11410-956-38 U Excluded because listing certification expired 0efc9e666f02…f202fb6c5f17…2025-01-11 03:41 UTC · source 2025-01-10 excluded package package 11410-956-17 U Excluded because listing certification expired 0efc9e666f02…f202fb6c5f17…2025-01-11 03:41 UTC · source 2025-01-10 excluded package package 11410-956-44 U Excluded because listing certification expired 0efc9e666f02…f202fb6c5f17…
Source provenance: Browse the complete Orange Book source catalog · source snapshot 1 .
Orange Book products# Current product rows page 1 of 1 · 1 matching rows.
Application-product, Trade name, Ingredient table Application-product Trade name Ingredient Strength Dosage form / route TE codes RLD / RS Approval date N020380-002 DIFFERIN ADAPALENE 0.1% GEL / TOPICAL RLD, RS 2016-07-08
Observed Orange Book product history# Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.
Product history page 1 of 2 · 41 observed states.
Captured, Edition, Application-product table Captured Edition Application-product Trade name Strength Dosage form / route Product TE source text RLD / RS Approval date Source SHA-256 2026-02-19 14:30 UTC 2026-02 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 011fe1cb6892…2025-12-14 10:44 UTC · 2 captures of this ZIP 2025-12 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 31067a03dcf5…2025-08-23 18:47 UTC 2025-08 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 6a471c1ec25d…2025-03-22 03:13 UTC · 3 captures of this ZIP 2025-03 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 fd3edfee7708…2025-02-26 10:13 UTC · 3 captures of this ZIP 2025-02 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 b8a1b40f171c…2025-01-19 17:59 UTC · 7 captures of this ZIP 2025-01 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 03ed91905a0d…2024-12-13 21:23 UTC · 2 captures of this ZIP 2024-12 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 2680178bc6a6…2024-09-14 05:58 UTC · 2 captures of this ZIP 2024-09 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 5bbf6a4d5a75…2024-11-08 22:44 UTC · 3 captures of this ZIP 2024-11 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 d8e5a09893c0…2024-10-29 15:01 UTC 2024-10 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 d06236e962d9…2024-08-13 05:28 UTC · 3 captures of this ZIP 2024-08 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 79d66fd596c7…2024-07-13 05:37 UTC · 2 captures of this ZIP 2024-07 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 301d65b070ca…2024-06-18 03:08 UTC · 5 captures of this ZIP 2024-06 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 1e350fbaab3a…2024-05-31 18:47 UTC 2024-05 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 8072bd15b7f6…2022-06-29 02:47 UTC · 2 captures of this ZIP 2022-06 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 5c6f7cd8ea54…2022-04-08 23:34 UTC 2022-04 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 5d02ea3f76ae…2022-04-04 05:41 UTC 2022-04 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 4b0b4de00fa7…2019-12-13 00:20 UTC 2019-12 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 74a2ff9319b5…2022-03-09 01:35 UTC 2022-03 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 bb7c543d1eb4…2021-12-28 21:50 UTC 2021-12 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 782e0a99824c…2021-05-05 16:15 UTC · 3 captures of this ZIP 2021-05 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 87673890dc5c…2021-03-12 10:30 UTC 2021-03 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 5aa47cf7b7d7…2020-12-22 03:56 UTC 2020-12 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 8869cabd3fbd…2020-11-12 02:37 UTC 2020-11 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 c0c555d07b60…2019-12-14 00:12 UTC 2019-12 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 3f01610625f2…2019-09-15 20:21 UTC 2019-09 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 b00525d2431f…2019-07-19 19:46 UTC 2019-07 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 ea99ee380514…2024-03-16 18:09 UTC · 4 captures of this ZIP 2024-03 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 6a51e52b5d6a…2024-02-18 07:12 UTC 2024-02 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 1c564ffb4f44…2023-12-20 04:57 UTC 2023-12 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 ea1830bbd6c7…2023-11-28 05:40 UTC · 2 captures of this ZIP 2023-11 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 a72a2bbeb626…2023-10-25 00:34 UTC · 2 captures of this ZIP 2023-10 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 9b2671bbb829…2023-07-15 15:27 UTC · 2 captures of this ZIP 2023-07 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 a67488948f0b…2023-06-13 01:57 UTC · 3 captures of this ZIP 2023-06 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 3f0d92c62455…2023-05-13 08:27 UTC 2023-05 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 053a50430f4f…2023-01-26 05:58 UTC 2023-01 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 3bdfa0b2c4d7…2022-11-12 20:34 UTC · 5 captures of this ZIP 2022-11 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 3a93d1ddd44b…2022-10-28 04:53 UTC 2022-10 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 f41ea6bd6efb…2022-09-29 23:25 UTC 2022-09 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 e64feba35796…2022-07-09 03:26 UTC · 3 captures of this ZIP 2022-07 N020380-002 DIFFERIN 0.1% GEL / TOPICAL RLD, RS 2016-07-08 cb3db0bc1861…
Observed Orange Book exclusivity history# Captured, Edition, Application-product table Captured Edition Application-product Exclusivity code Expiration Source SHA-256 2019-12-13 00:20 UTC 2019-12 N020380-002 RTO 2019-07-08 74a2ff9319b5…2019-12-14 00:12 UTC 2019-12 N020380-002 RTO 2019-07-08 3f01610625f2…2019-09-15 20:21 UTC 2019-09 N020380-002 RTO 2019-07-08 b00525d2431f…2019-07-19 19:46 UTC 2019-07 N020380-002 RTO 2019-07-08 ea99ee380514…
FDA-Initiated Inactive NDC Indexing# DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 11410-956 PROACTIV MD ADAPALENE ACNE TREATMENT (ADAPALENE) GEL [ALCHEMEE, LLC] 4 Legacy NDC 20221201_ab771c7e-ed01-442c-be0e-d368db6e4100.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 1 of 1 · 1 matching rows.
Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Units Marketing start Marketing end Sample Exclude flag Status 11410-956-17 11410095617 1 TUBE in 1 BOX (11410-956-17) > 45 g in 1 TUBE 1 tube 2017-03-27 0000-00-00 No No Current 11410-956-38 11410095638 1 TUBE in 1 BLISTER PACK (11410-956-38) > 2 g in 1 TUBE 1 tube 2017-08-09 0000-00-00 No No Current 11410-956-44 11410095644 1 TUBE in 1 BOX (11410-956-44) > 15 g in 1 TUBE 1 tube 2017-03-27 0000-00-00 No No Current