Adapalene

Product NDC
51672-4155
11-digit product format
516724155
Labeler code
51672
Product ID
51672-4155_9ad52567-50fc-4046-812b-7a3f01492444
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Adapalene
Dosage form
GEL
Route
TOPICAL
Labeler
Taro Pharmaceuticals U.S.A., Inc.
Application
NDA020380
Marketing category
NDA AUTHORIZED GENERIC
Marketing start
1996-05-31
Marketing end
0000-00-00
Substance
ADAPALENE
Active strength
1 mg/g
Pharmacologic classes
Retinoid [EPC],Retinoids [CS]
NDC exclude flag
E
Listing certified through
2018-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct51672-4155DDiscontinued by firm2026-08-17
excluded packagepackage51672-415551672-4155-6DDiscontinued by firm2026-08-17

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 24 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage51672-4155-6d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded productproductf5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage51672-4155-6f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-31excluded productproduct2ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-31excluded packagepackage51672-4155-62ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28excluded productproducta1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-28excluded packagepackage51672-4155-6a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21excluded productproductcfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-21excluded packagepackage51672-4155-6cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10excluded productproductcdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-10excluded packagepackage51672-4155-6cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31excluded productproduct302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage51672-4155-6302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20excluded productproducted331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage51672-4155-6ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-10excluded productproduct0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage51672-4155-60efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08excluded productproductad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-08excluded packagepackage51672-4155-6ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03excluded productproduct367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage51672-4155-6367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09excluded productproduct557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage51672-4155-6557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N020380-002DIFFERINADAPALENE0.1%GEL / TOPICALRLD, RS2016-07-08

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 42 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-0831067a03dcf5…
2025-08-23 18:47 UTC2025-08N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-086a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-0803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-082680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-085bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-0879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-081e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-088072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-085c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-085d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-084b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-0874a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-0887673890dc5c…
2021-03-12 10:30 UTC2021-03N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-085aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-088869cabd3fbd…
2020-11-12 02:37 UTC2020-11N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08c0c555d07b60…
2019-12-14 00:12 UTC2019-12N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-083f01610625f2…
2019-09-15 20:21 UTC2019-09N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08b00525d2431f…
2019-07-19 19:46 UTC2019-07N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-086a51e52b5d6a…
2024-02-18 07:12 UTC2024-02N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-081c564ffb4f44…
2023-12-20 04:57 UTC2023-12N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-089b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-083f0d92c62455…
2023-05-13 08:27 UTC2023-05N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08053a50430f4f…
2023-01-26 05:58 UTC2023-01N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-083bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-083a93d1ddd44b…
2022-10-28 04:53 UTC2022-10N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09N020380-002DIFFERIN0.1%GEL / TOPICALRLD, RS2016-07-08e64feba35796…

Observed Orange Book exclusivity history#

Captured, Edition, Application-product table
CapturedEditionApplication-productExclusivity codeExpirationSource SHA-256
2019-12-13 00:20 UTC2019-12N020380-002RTO2019-07-0874a2ff9319b5…
2019-12-14 00:12 UTC2019-12N020380-002RTO2019-07-083f01610625f2…
2019-09-15 20:21 UTC2019-09N020380-002RTO2019-07-08b00525d2431f…
2019-07-19 19:46 UTC2019-07N020380-002RTO2019-07-08ea99ee380514…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
51672-4155-6GM - Gram51672-4155e4787a48-1b55-4533-af98-29b9f594df7b12012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
AdapaleneACTIVE INGREDIENT1L4806J2QFADAPALENE GEL [TARO PHARMACEUTICALS U.S.A., INC.]3
AdapaleneACTIVE MOIETY1L4806J2QFADAPALENE GEL [TARO PHARMACEUTICALS U.S.A., INC.]3
CARBOMER 940INACTIVE INGREDIENT4Q93RCW27EADAPALENE GEL [TARO PHARMACEUTICALS U.S.A., INC.]3
EDETATE DISODIUMINACTIVE INGREDIENT7FLD91C86KADAPALENE GEL [TARO PHARMACEUTICALS U.S.A., INC.]3
HYDROCHLORIC ACIDINACTIVE INGREDIENTQTT17582CBADAPALENE GEL [TARO PHARMACEUTICALS U.S.A., INC.]3
METHYLPARABENINACTIVE INGREDIENTA2I8C7HI9TADAPALENE GEL [TARO PHARMACEUTICALS U.S.A., INC.]3
POLOXAMER 182INACTIVE INGREDIENTJX0HIX6OAGADAPALENE GEL [TARO PHARMACEUTICALS U.S.A., INC.]3
PROPYLENE GLYCOLINACTIVE INGREDIENT6DC9Q167V3ADAPALENE GEL [TARO PHARMACEUTICALS U.S.A., INC.]3
SODIUM HYDROXIDEINACTIVE INGREDIENT55X04QC32IADAPALENE GEL [TARO PHARMACEUTICALS U.S.A., INC.]3
WATERINACTIVE INGREDIENT059QF0KO0RADAPALENE GEL [TARO PHARMACEUTICALS U.S.A., INC.]3

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
DifferinADAPALENEGalderma Laboratories, L.P.0739d631-171b-42a8-bd55-0022b8df2d8a2022-12-07WarningsExact identifier
application applno (NDA): 020380
application number: NDA020380