REFRESH Classic

Product NDC: 0023-0506
11-digit product format: 000230506
Labeler code: 0023
Product ID: 0023-0506_58d49977-1915-4473-801d-a28b87b9a328
Type: HUMAN OTC DRUG
Nonproprietary name: Polyvinyl Alcohol, Povidone
Dosage form: SOLUTION/ DROPS
Route: OPHTHALMIC
Labeler: Allergan, Inc.
Application: M018
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 1985-09-12
Substance: POLYVINYL ALCOHOL, UNSPECIFIED; POVIDONE
Active strength: 14; 6 mg/mL; mg/mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: REFRESH Classic
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
POLYVINYL ALCOHOL, UNSPECIFIED	14 mg/mL
POVIDONE	6 mg/mL

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
0023-0506-01	REFRESH Classic	0.4 mL in 1 VIAL, SINGLE-USE	SOLUTION/ DROPS	0.4	11
0023-0506-01	REFRESH Classic	30 in 1 CARTON	SOLUTION/ DROPS	30	11
0023-0506-50	REFRESH Classic	50 in 1 CARTON	SOLUTION/ DROPS	50	11
0023-0506-50	REFRESH Classic	0.4 mL in 1 VIAL, SINGLE-USE	SOLUTION/ DROPS	0.4	11

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0023-0506-01	EA - Each	0023-0506	6f103f52-b51b-4112-8b6f-0dbff9ac462a	1	2012-07-24
0023-0506-50	EA - Each	0023-0506	d349c8e5-b120-43bc-a75d-eb0c165a554e	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Polyvinyl Alcohol	ACTIVE INGREDIENT	532B59J990	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
Povidone	ACTIVE INGREDIENT	FZ989GH94E	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
Polyvinyl Alcohol	ACTIVE MOIETY	532B59J990	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
Povidone	ACTIVE MOIETY	FZ989GH94E	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
hydrochloric acid	INACTIVE INGREDIENT	QTT17582CB	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
sodium chloride	INACTIVE INGREDIENT	451W47IQ8X	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
sodium hydroxide	INACTIVE INGREDIENT	55X04QC32I	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4
water	INACTIVE INGREDIENT	059QF0KO0R	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	4

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0023-0506	REFRESH CLASSIC (POLYVINYL ALCOHOL, POVIDONE) SOLUTION/ DROPS [ALLERGAN, INC.]	10	Current NDC, Legacy NDC, 4 package rows	20240214_31bf1d6c-9719-4060-b6a3-409a2fe7b560.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 17 of 25 · 494 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Eyesaline Eyewash Concentrate	PURIFIED WATER	Honeywell Safety Products, Inc.	2d90c8e8-f479-3535-e063-6394a90af122	2025-02-07	Warnings	Exact identifier application number: M018
Code Red Eye Drops Redness Relief	POLYETHYLENE GLYCOL 400, TETRAHYDROZOLINE HCL	4 Trees, LLC	0aa08018-cc2d-d947-e063-6394a90a914a	2025-02-07	Warnings	Exact identifier application number: M018
Tyson 2.0 Mike Red Eye Drops For Dry High Eyes	GLYCERIN, NAPHAZOLINE HCL	Jbrands Pharma L.L.C.	288e9c85-0562-89bf-e063-6394a90a110d	2025-02-07	Warnings	Exact identifier application number: M018
Sodium Chloride Normal Salt	SODIUM CHLORIDE	Citragen Pharmaceuticals Inc	aae783b2-18fe-69ca-e053-2a95a90a0800	2025-01-30	Warnings	Exact identifier application number: M018
Sodium Chloride Normal Salt	SODIUM CHLORIDE	Citragen Pharmaceuticals Inc	82c29f1d-a018-7483-e053-2a91aa0a8f7e	2025-01-30	Warnings	Exact identifier application number: M018
OASIS Tears Lubricant Eye	GLYCERIN	OASIS Medical, Inc.	00071697-4ac6-4962-8eee-388b8b52bd40	2025-01-22	Warnings	Exact identifier application number: M018
ImproVue Lubricant	HYPROMELLOSE 2208 (15000 MPA.S)	Oculus Surgical, Inc.	63b82129-4848-47c5-bf92-ec4b1a9e9974	2025-01-22	Warnings	Exact identifier application number: M018
VISCO SHIELD Lubricant	HYPROMELLOSE 2208 (15000 MPA.S)	OASIS Medical, Inc.	72d22610-d8ab-4f24-b304-8b013430a7d7	2025-01-22	Warnings	Exact identifier application number: M018
OASIS Tears Plus Preservative-Free Lubricant Eye	GLYCERIN	OASIS Medical, Inc.	ea931c0f-c61e-4771-84f1-0274b1c3e28e	2025-01-22	Warnings	Exact identifier application number: M018
Medics Choice Soothing Eye Wash	PURIFIED WATER	KC Pharmaceuticals, Inc.	10e49808-161e-f4ec-e063-6294a90a1775	2025-01-19	Warnings	Exact identifier application number: M018
Sodium Chloride Hypertonicity Ophthalmic Solution, 5%	SODIUM CHLORIDE HYPERTONICITY OPHTHALMIC SOLUTION, 5%	Reliable 1 Laboritories LLC	29175c17-223e-5e92-e063-6294a90a71d2	2025-01-15	Warnings	Exact identifier application number: M018
Lubricating Tears	CARBOXYMETHYLCELLULOSE SODIUM 0.5% SOLUTION	Reliable 1 Laboritories LLC	29023a57-eba3-4241-e063-6294a90a7048	2025-01-15	Warnings	Exact identifier application number: M018
Aurodone Povidone Iodine 5 % Opthalmic Solution	POVIDONE IODINE 5 % TOPICAL SOLUTION	Aurolab	f3444446-1dad-79ff-e053-2a95a90af411	2025-01-06	Warnings	Exact identifier application number: M018
Hypromellose Eye Drops 0.7%	HYPROMELLOSE EYE DROPS 0.7%	Aurolab	d35313d0-b190-5fb0-e053-2a95a90a5283	2025-01-02	Warnings	Exact identifier application number: M018
VISTA MEIBO TEARS Propylene Glycol 0.6% w/v Advanced Dry Eye Relief Lubricating Drops 10 ml	PROPYLENE GLYCOL	Red Wedding LLC	b2c2fd0f-b944-6b0b-e053-2995a90aa216	2025-01-01	Warnings	Exact identifier application number: M018
Rite Aid Hydration Lubricant Eye Drops	POLYETHYLENE GLYCOL 400, PROPYLENE GLYCOL	Rite Aid Corporation	ecac1351-e944-21da-e053-2995a90a6d34	2024-12-31	Warnings	Exact identifier application number: M018
Lubricant Eye PM	MINERAL OIL, WHITE PETROLATUM	Reliable 1 Laboratories LLC	baec8045-97fe-6f60-e053-2a95a90a050e	2024-12-31	Warnings	Exact identifier application number: M018
Lil Drug Store Eye Drops Redness Reliever	TETRAHYDROZOLINE HYDROCHLORIDE	Lil Drug Store Products, Inc	d2a47e98-a04c-47ec-aded-d1c894f040e2	2024-12-30	Warnings	Exact identifier application number: M018
Rain Renewal Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM	Rain Eye Drops, LLC	af7a5768-7d1d-3d93-e053-2a95a90a38f6	2024-12-29	Warnings	Exact identifier application number: M018
Glitch Advanced Relief Eye Drops	POLYETHYLENE GLYCOL 400, TETRAHYDROZOLINE HCL	Misemer Pharmaceutical, Inc	03778509-3374-2168-e063-6294a90a9505	2024-12-23	Warnings	Exact identifier application number: M018

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
532B59J990	POLYVINYL ALCOHOL, UNSPECIFIED	9002-89-5	POLYVINYL ALCOHOL, UNSPECIFIED

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
359969	polyvinyl alcohol 1.4 % / povidone 0.6 % Ophthalmic Solution	PSN	3bf6193c-56db-45ad-844c-58eb8c33cba9	18
359969	polyvinyl alcohol 0.014 ML/ML / povidone 6 MG/ML Ophthalmic Solution	SCD	3bf6193c-56db-45ad-844c-58eb8c33cba9	18
359969	polyvinyl alcohol 1.4 % / povidone 0.6 % Ophthalmic Solution	SY	3bf6193c-56db-45ad-844c-58eb8c33cba9	18
359969	polyvinyl alcohol 1.4 % / povidone 0.6 % Ophthalmic Solution	PSN	31bf1d6c-9719-4060-b6a3-409a2fe7b560	11
359969	polyvinyl alcohol 0.014 ML/ML / povidone 6 MG/ML Ophthalmic Solution	SCD	31bf1d6c-9719-4060-b6a3-409a2fe7b560	11
359969	polyvinyl alcohol 1.4 % / povidone 0.6 % Ophthalmic Solution	SY	31bf1d6c-9719-4060-b6a3-409a2fe7b560	11

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
0023-0506-01	00023050601	30 VIAL, SINGLE-USE in 1 CARTON (0023-0506-01) / .4 mL in 1 VIAL, SINGLE-USE	1985-09-12	0000-00-00	No	No	Current
0023-0506-50	00023050650	50 VIAL, SINGLE-USE in 1 CARTON (0023-0506-50) / .4 mL in 1 VIAL, SINGLE-USE	1985-09-12	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
REFRESH ® Classic ( P reservative-free ) Drug Facts	Allergan, Inc.	2026-09-15	HUMAN OTC DRUG LABEL	12
REFRESH CLASSIC	A-S Medication Solutions	2024-03-14	HUMAN OTC DRUG LABEL	18