REFRESH LIQUIGEL

Product NDC: 0023-9205
11-digit product format: 000239205
Labeler code: 0023
Product ID: 0023-9205_c0ff3bb9-b271-4607-8623-38e1bc7e3e99
Type: HUMAN OTC DRUG
Nonproprietary name: Carboxymethylcellulose sodium
Dosage form: GEL
Route: OPHTHALMIC
Labeler: Allergan, Inc.
Application: M018
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2001-10-04
Substance: CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED
Active strength: 10 mg/mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	0023-9205	0023-9205-02	D	Discontinued by firm		2026-10-12
excluded package	package	0023-9205	0023-9205-03	D	Discontinued by firm		2026-10-12

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 24 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Package NDC, Snapshot table
Captured / source date	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	0023-9205-03	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	0023-9205-02	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	0023-9205-03	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	0023-9205-02	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	0023-9205-03	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	0023-9205-02	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	0023-9205-03	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	0023-9205-02	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	0023-9205-03	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	0023-9205-02	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	0023-9205-03	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	0023-9205-02	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	0023-9205-03	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	0023-9205-02	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	0023-9205-03	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	0023-9205-02	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	0023-9205-03	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	0023-9205-02	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	0023-9205-02	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	0023-9205-03	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	0023-9205-02	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	0023-9205-03	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	0023-9205-02	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	0023-9205-03	`557ba5c1ecfa…`	`9c80585c8c6e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: REFRESH LIQUIGEL
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED	10 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
K679OBS311	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
579907	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
4b8b2f6a-4b89-446c-9e5b-9b83c453a01d	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
9e37788c-b1bf-42ae-aac9-b60601606144	Product name	8	20260122
30b0ac6e-02aa-0e5c-0d8b-cffdf3a282b2	Product name	5	20250304
1527ac37-808d-43be-a63e-74e1258dbe46	Product name	9	20250219
bed0530e-f939-4541-956b-6928a2f6404f	Product name	1	20241008
cefa60e2-a5b5-493e-9c54-24735b7dc509	Product name	6	20240814
362d7abb-94e6-4c60-9a58-266894157713	Product name	1	20231023
9fcb7a91-de07-4f00-aabf-e4d6fda403d5	Product name	8	20230322
6bd95106-a412-1dad-b9cc-4cb74bfb27ce	Product name	2	20230315
9badc7be-250a-44ab-aa36-926af3f02679	Product name	1	20210527
0ec3537a-6c9b-432a-896c-b9ea8723049a	Product name	9	20200701
444b3e50-f226-46ef-bfca-2e7035d140cd	Product name	1	20190611
816b97af-edc5-4060-aff1-b814bdbcad50	Product name	1	20190415
7cda52fc-125f-421c-8fea-bc1974370c49	Product name	2	20180703
7916de40-e296-41f0-b811-6d0df1a33e2c	Product name	9	20180627
cefa60e2-a5b5-493e-9c54-24735b7dc509	Product name	2	20171212
419aab54-5d5a-4146-9453-026d4a9991be	Product name	2	20170525
d5e51f11-ad28-caa4-4b49-4143974782ad	Product name	1	20150831
290f523a-f9db-9774-b5a9-e1f908ac1782	Product name	1	20150828
0ca1d589-929b-4b33-bc5b-1d84abdafa6a	Product name	1	20150324
fc363c46-397b-4476-ac0f-70e43e8e4592	Product name	1	20150324
89dac932-b90a-4410-9ab1-84c53e57de25	Product name	1	20150316
5668b646-cd56-c3c7-bdea-3f6b1a8840db	Product name	1	20140508
810ab97e-f109-f41c-7c83-6a652a9cbf43	Product name	1	20140508
87711080-88eb-65c5-b2dd-bf99e700a372	Product name	1	20140508
8dbefedf-0a0d-a224-5a3c-66dc9e11c2dd	Product name	1	20140508
c6b65c52-69c7-df49-550a-a50c137f6218	Product name	1	20140508
ec2149b3-5c6d-5344-f757-c86411073075	Product name	1	20140508
ed912195-5da0-0f2f-6f4b-3ef17710cbe3	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
0023-9205-02	REFRESH LIQUIGEL	15 mL in 1 BOTTLE, DROPPER	GEL	15	8
0023-9205-02	REFRESH LIQUIGEL	2 in 1 CARTON	GEL	2	8
0023-9205-03	REFRESH LIQUIGEL	1 in 1 CARTON	GEL	1	8
0023-9205-03	REFRESH LIQUIGEL	3 mL in 1 BOTTLE, DROPPER	GEL	3	8
0023-9205-15	REFRESH LIQUIGEL	15 mL in 1 BOTTLE, DROPPER	GEL	15	8
0023-9205-15	REFRESH LIQUIGEL	1 in 1 CARTON	GEL	1	8

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0023-9205-02	ML - Milliliter	0023-9205	a067bbcf-1abb-458b-bcb2-1e995aaebfc7	1	2012-07-24
0023-9205-15	ML - Milliliter	0023-9205	993a5446-6b4c-4982-9a8f-4e53ab18dfb3	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Carboxymethylcellulose sodium	ACTIVE INGREDIENT	K679OBS311	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
Carboxymethylcellulose	ACTIVE MOIETY	05JZI7B19X	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
Boric acid	INACTIVE INGREDIENT	R57ZHV85D4	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
calcium chloride	INACTIVE INGREDIENT	M4I0D6VV5M	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
chlorine dioxide	INACTIVE INGREDIENT	8061YMS4RM	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
magnesium chloride	INACTIVE INGREDIENT	02F3473H9O	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
potassium chloride	INACTIVE INGREDIENT	660YQ98I10	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
sodium borate	INACTIVE INGREDIENT	91MBZ8H3QO	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
sodium chlorate	INACTIVE INGREDIENT	T95DR77GMR	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
sodium chloride	INACTIVE INGREDIENT	451W47IQ8X	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
sodium chlorite	INACTIVE INGREDIENT	G538EBV4VF	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
water	INACTIVE INGREDIENT	059QF0KO0R	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0023-9205	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	8	Current NDC, Legacy NDC, 6 package rows	20241113_4b8b2f6a-4b89-446c-9e5b-9b83c453a01d.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 3 of 25 · 494 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Visine Red Eye Total Comfort Multi-Symptom	TETRAHYDROZOLINE HYDROCHLORIDE, POLYETHYLENE GLYCOL 400, AND ZINC SULFATE, UNSPECIFIED FORM	Kenvue Brands LLC	5747edef-7a87-41d7-9594-6c78508b9ba2	2026-06-11	Warnings	Exact identifier application number: M018
Nano Eye Drop Serum	WATER. SORBITOL.1.2-HEXANEDIOL GLYCERIN HYALURONATESODIUM.	Shenzhen Yiyang Zhiting Technology Co., Ltd	539567d6-488a-9b01-e063-6394a90abece	2026-06-06	Warnings	Exact identifier application number: M018
REFRESH CELLUVISC	CARBOXYMETHYLCELLULOSE SODIUM	Allergan, Inc.	b32ed9e8-d091-4f16-b416-5a62cdfee49a	2026-06-05	Warnings	Exact identifier application number: M018
VitaPhyte Redness Reliever Lubricant Eye Drops	REDNESS RELIEVER LUBRICANT EYE DROPS	Guangzhou Liyan Cosmetics Technology Co., Ltd.	53d4e9b0-c9a0-797a-e063-6294a90ad0cf	2026-06-04	Warnings	Exact identifier application number: M018
Rohto Digi-Eye	HYPROMELLOSE, TETRAHYDROZOLINE HYDROCHLORIDE	The Mentholatum Company	5d6f37b9-b568-4cb6-92de-eb40779f3f8c	2026-06-03	Warnings	Exact identifier application number: M018
Visine Red Eye Hydrating Comfort Eye Drops	TETRAHYDROZOLINE HYDROCHLORIDE AND POLYETHYLENE GLYCOL 400	Savings Distributors LLC	558178eb-1eec-af0f-e063-6394a90afad9	2026-06-01	Warnings	Exact identifier application number: M018
C-More Lubricant Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM, GLYCERIN	PROFOUND NUTRITION LIMITED	78f04ecb-da5e-468c-81fe-70f7c26b76c2	2026-06-01	Warnings	Exact identifier application number: M018
Peep Club	GLYCERIN	Peep Club Eyecare Corp.	513d1988-2827-28d8-e063-6294a90a8d1f	2026-05-28	Warnings	Exact identifier application number: M018
Blink Triple Care Preservative Free	POLYETHYLENE GLYCOL 400	Bausch & Lomb Incorporated	65e67990-78b7-4ce9-963b-6bed3a6bed07	2026-05-27	Warnings	Exact identifier application number: M018
Ripple	GLYCERIN, POVIDONE	CorneaCare Inc	3b5ba197-d501-681e-e063-6294a90aefb5	2026-05-24	Warnings	Exact identifier application number: M018
REFRESH LACRI-LUBE	MINERAL OIL, PETROLATUM	Allergan, Inc.	d232a44b-516d-4cdf-a4e7-c3a9a50dc7af	2026-05-15	Warnings	Exact identifier application number: M018
blink tears	POLYETHYLENE GLYCOL 400	Bausch & Lomb Incorporated	f1d07347-086f-43b2-aa5f-910764fc666e	2026-05-13	Warnings	Exact identifier application number: M018
Systane Pro PF	PROPYLENE GLYCOL	Alcon Laboratories, Inc.	a12baf3d-f22b-4c9f-a4c8-4e0d09f6d6f1	2026-05-12	Warnings	Exact identifier application number: M018
Sodium Hyaluronate Eye Drops	SODIUM HYALURONATE	Guangzhou Hechuang Commercial Service Co.,Ltd.	5187d136-15c6-517b-e063-6294a90a811d	2026-05-11	Warnings	Exact identifier application number: M018
Splash Tears	HYPROMELLOSE	LABORATORIOS SOPHIA, S.A. DE C.V.	a58a8478-9cc5-aa39-e053-2995a90a347d	2026-05-08	Warnings	Exact identifier application number: M018
iVIZIA Lubricant Eye Gel	POVIDONE	Thea Pharma Inc.	1f06ca1a-5270-9a82-e063-6294a90aed64	2026-04-29	Warnings	Exact identifier application number: M018
GoodSense Eye Drops Advanced Relief Moisturizer	DEXTRAN, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCL	Preferred PHarmaceuticals Inc.	011473a8-26d5-4661-b3c0-745f9b6aa1d8	2026-04-29	Warnings	Exact identifier application number: M018
REFRESH TEARS PF	CARBOXYMETHYLCELLULOSE SODIUM, GLYCERIN	Allergan, Inc.	9e1cba7b-84ed-47f3-b19a-121992834350	2026-04-24	Warnings	Exact identifier application number: M018
Sodium Chloride	SODIUM CHLORIDE	Method Pharmaceuticals, LLC	4b08859e-65bd-8255-e063-6394a90af614	2026-04-23	Warnings	Exact identifier application number: M018
Pure Eyes Sterile Eyes	NAPHAZOLINE HYDROCHLORIDE AND GLYCERIN	SAMSON PHARMACEUTICAL	c0234e82-211f-4731-ac48-12db13b16e8a	2026-04-21	Warnings	Exact identifier application number: M018

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
579907	carboxymethylcellulose sodium 1 % Ophthalmic Gel	PSN	4b8b2f6a-4b89-446c-9e5b-9b83c453a01d	8
579907	carboxymethylcellulose sodium 0.01 MG/MG Ophthalmic Gel	SCD	4b8b2f6a-4b89-446c-9e5b-9b83c453a01d	8
579907	carboxymethylcellulose sodium 1 % Ophthalmic Gel	SY	4b8b2f6a-4b89-446c-9e5b-9b83c453a01d	8

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
0023-9205-02	00023920502	2 BOTTLE, DROPPER in 1 CARTON (0023-9205-02) > 15 mL in 1 BOTTLE, DROPPER	2001-10-04	0000-00-00	No	No	Current
0023-9205-03	00023920503	1 BOTTLE, DROPPER in 1 CARTON (0023-9205-03) > 3 mL in 1 BOTTLE, DROPPER	2001-10-04	0000-00-00	No	No	Current
0023-9205-15	00023920515	1 BOTTLE, DROPPER in 1 CARTON (0023-9205-15) / 15 mL in 1 BOTTLE, DROPPER	2001-10-04	0000-00-00	No	No	Current