REFRESH LIQUIGEL

Product NDC: 0023-9205
11-digit product format: 000239205
Labeler code: 0023
Product ID: 0023-9205_c0ff3bb9-b271-4607-8623-38e1bc7e3e99
Type: HUMAN OTC DRUG
Nonproprietary name: Carboxymethylcellulose sodium
Dosage form: GEL
Route: OPHTHALMIC
Labeler: Allergan, Inc.
Application: M018
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2001-10-04
Substance: CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED
Active strength: 10 mg/mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	0023-9205	0023-9205-02	D	Discontinued by firm		2026-10-12
excluded package	package	0023-9205	0023-9205-03	D	Discontinued by firm		2026-10-12

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 24 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Package NDC, Snapshot table
Captured / source date	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	0023-9205-03	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	0023-9205-02	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	0023-9205-03	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	0023-9205-02	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	0023-9205-03	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	0023-9205-02	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	0023-9205-03	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	0023-9205-02	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	0023-9205-03	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	0023-9205-02	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	0023-9205-03	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	0023-9205-02	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	0023-9205-03	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	0023-9205-02	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	0023-9205-03	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	0023-9205-02	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	0023-9205-03	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	0023-9205-02	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	0023-9205-02	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	0023-9205-03	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	0023-9205-02	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	0023-9205-03	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	0023-9205-02	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	0023-9205-03	`557ba5c1ecfa…`	`9c80585c8c6e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: REFRESH LIQUIGEL
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED	10 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
K679OBS311	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
579907	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
4b8b2f6a-4b89-446c-9e5b-9b83c453a01d	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
9e37788c-b1bf-42ae-aac9-b60601606144	Product name	8	20260122
30b0ac6e-02aa-0e5c-0d8b-cffdf3a282b2	Product name	5	20250304
1527ac37-808d-43be-a63e-74e1258dbe46	Product name	9	20250219
bed0530e-f939-4541-956b-6928a2f6404f	Product name	1	20241008
cefa60e2-a5b5-493e-9c54-24735b7dc509	Product name	6	20240814
362d7abb-94e6-4c60-9a58-266894157713	Product name	1	20231023
9fcb7a91-de07-4f00-aabf-e4d6fda403d5	Product name	8	20230322
6bd95106-a412-1dad-b9cc-4cb74bfb27ce	Product name	2	20230315
9badc7be-250a-44ab-aa36-926af3f02679	Product name	1	20210527
0ec3537a-6c9b-432a-896c-b9ea8723049a	Product name	9	20200701
444b3e50-f226-46ef-bfca-2e7035d140cd	Product name	1	20190611
816b97af-edc5-4060-aff1-b814bdbcad50	Product name	1	20190415
7cda52fc-125f-421c-8fea-bc1974370c49	Product name	2	20180703
7916de40-e296-41f0-b811-6d0df1a33e2c	Product name	9	20180627
cefa60e2-a5b5-493e-9c54-24735b7dc509	Product name	2	20171212
419aab54-5d5a-4146-9453-026d4a9991be	Product name	2	20170525
d5e51f11-ad28-caa4-4b49-4143974782ad	Product name	1	20150831
290f523a-f9db-9774-b5a9-e1f908ac1782	Product name	1	20150828
0ca1d589-929b-4b33-bc5b-1d84abdafa6a	Product name	1	20150324
fc363c46-397b-4476-ac0f-70e43e8e4592	Product name	1	20150324
89dac932-b90a-4410-9ab1-84c53e57de25	Product name	1	20150316
5668b646-cd56-c3c7-bdea-3f6b1a8840db	Product name	1	20140508
810ab97e-f109-f41c-7c83-6a652a9cbf43	Product name	1	20140508
87711080-88eb-65c5-b2dd-bf99e700a372	Product name	1	20140508
8dbefedf-0a0d-a224-5a3c-66dc9e11c2dd	Product name	1	20140508
c6b65c52-69c7-df49-550a-a50c137f6218	Product name	1	20140508
ec2149b3-5c6d-5344-f757-c86411073075	Product name	1	20140508
ed912195-5da0-0f2f-6f4b-3ef17710cbe3	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
0023-9205-02	REFRESH LIQUIGEL	15 mL in 1 BOTTLE, DROPPER	GEL	15	8
0023-9205-02	REFRESH LIQUIGEL	2 in 1 CARTON	GEL	2	8
0023-9205-03	REFRESH LIQUIGEL	1 in 1 CARTON	GEL	1	8
0023-9205-03	REFRESH LIQUIGEL	3 mL in 1 BOTTLE, DROPPER	GEL	3	8
0023-9205-15	REFRESH LIQUIGEL	15 mL in 1 BOTTLE, DROPPER	GEL	15	8
0023-9205-15	REFRESH LIQUIGEL	1 in 1 CARTON	GEL	1	8

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0023-9205-02	ML - Milliliter	0023-9205	a067bbcf-1abb-458b-bcb2-1e995aaebfc7	1	2012-07-24
0023-9205-15	ML - Milliliter	0023-9205	993a5446-6b4c-4982-9a8f-4e53ab18dfb3	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
Carboxymethylcellulose sodium	ACTIVE INGREDIENT	K679OBS311	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
Carboxymethylcellulose	ACTIVE MOIETY	05JZI7B19X	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
Boric acid	INACTIVE INGREDIENT	R57ZHV85D4	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
calcium chloride	INACTIVE INGREDIENT	M4I0D6VV5M	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
chlorine dioxide	INACTIVE INGREDIENT	8061YMS4RM	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
magnesium chloride	INACTIVE INGREDIENT	02F3473H9O	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
potassium chloride	INACTIVE INGREDIENT	660YQ98I10	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
sodium borate	INACTIVE INGREDIENT	91MBZ8H3QO	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
sodium chlorate	INACTIVE INGREDIENT	T95DR77GMR	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
sodium chloride	INACTIVE INGREDIENT	451W47IQ8X	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
sodium chlorite	INACTIVE INGREDIENT	G538EBV4VF	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2
water	INACTIVE INGREDIENT	059QF0KO0R	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
0023-9205	REFRESH LIQUIGEL (CARBOXYMETHYLCELLULOSE SODIUM) GEL [ALLERGAN, INC.]	8	Current NDC, Legacy NDC, 6 package rows	20241113_4b8b2f6a-4b89-446c-9e5b-9b83c453a01d.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 5 of 25 · 494 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Lubricant Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM	Redicare LLC	4d1e5089-22b0-7b3f-e063-6294a90a346a	2026-03-16	Warnings	Exact identifier application number: M018
Leader Ultra Lubricating Eye Drops	POLYETHYLENE GLYCOL 400, PROPYLENE GLYCOL	Cardinal Health	d7f011a2-05ba-47c3-9519-d31602e105c7	2026-03-12	Warnings	Exact identifier application number: M018
Leader Restorative Formula Lubricant Eye Drops	PROPYLENE GLYCOL	Cardinal Health	87fef7e4-e5a8-4aad-94d2-f80f34826d97	2026-03-12	Warnings	Exact identifier application number: M018
Leader Advanced Relief Eye Drops	DEXTRAN 70, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCL	Cardinal Health	5c5d6c13-9b51-48f0-8627-b60b0f707fd3	2026-03-12	Warnings	Exact identifier application number: M018
Focus PI	HYPROMELLOSE EYE DROPS 0.7%	COVALENT MEDICAL	e9b2afdd-049a-3987-e053-2a95a90a6cbb	2026-03-09	Warnings	Exact identifier application number: M018
Rain Renewal Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM	Rain Eye Drops, LLC	bb451b22-c4f6-291d-e053-2a95a90a7801	2026-03-06	Warnings	Exact identifier application number: M018
Complete Eye Relief Sterile Lubricant Eye Drops	HYDROXYETHYL CELLULOSE	Similasan Corporation	4c49493a-70f9-0fde-e063-6394a90aea20	2026-03-05	Warnings	Exact identifier application number: M018
Dry Eye Relief Sterile Lubricant Eye Drops	GLYCERIN	Similasan Corporation	4c4cce1c-392e-354d-e063-6294a90a0ca3	2026-03-05	Warnings	Exact identifier application number: M018
Irritated Eye Relief Sterile Lubricant Eye Drops	HYDROXYETHYL CELLULOSE	Similasan Corporation	4c4ddcdf-3037-c9cd-e063-6294a90a16d5	2026-03-05	Warnings	Exact identifier application number: M018
Refresh Optive Mega-3 PF	CARBOXYMETHYLCELLULOSE SODIUM, GLYCERIN, POLYSORBATE 80	Allergan, Inc.	326cb5d6-c784-404f-9a13-6d69262dda6e	2026-03-01	Warnings	Exact identifier application number: M018
Discount Drug Mart Lubricant Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM	Discount Drug Mart	4ba1b369-54e2-5224-e063-6394a90a4769	2026-02-25	Warnings	Exact identifier application number: M018
Lubricant Eye Drops	CARBOXYMETHYLCELLULOSE SODIUM	KC Pharmaceuticals, Inc.	4bafa882-50b7-e3e2-e063-6294a90a76e3	2026-02-25	Warnings	Exact identifier application number: M018
Viva Hydration Boost	GLYCERIN	Nomax Inc	174193b2-65eb-b5fd-e063-6394a90a9cd0	2026-02-10	Warnings	Exact identifier application number: M018
Droptics Performance Eye Drops	NAPHAZOLINE HYDROCHLORIDE, PROPYLENE GLYCOL	Droptics LLC	20fd6822-a7fd-4593-92bb-0a07260893e2	2026-02-09	Warnings	Exact identifier application number: M018
GoodSense Eye Drops Advanced Relief Moisturizer	DEXTRAN, POLYETHYLENE GLYCOL 400, POVIDONE, TETRAHYDROZOLINE HCL	Sportpharm LLC	8d58dcbb-72a0-41f0-9eeb-613072a6d7ae	2026-02-06	Warnings	Exact identifier application number: M018
MINIDROPS	LUBRICANT EYE DROPS	Optics Laboratory, Inc	c13c5f91-50df-471c-a7c9-1747a2ac1250	2026-02-03	Warnings	Exact identifier application number: M018
Optase	WHITE PETROLATUM, LANOLIN	Scope Health Inc	c1991caa-51b9-13d1-e053-2995a90a1293	2026-01-31	Warnings	Exact identifier application number: M018
Optase	GLYCERIN	Scope Health Inc	376e0289-28e9-e87f-e063-6294a90a3b04	2026-01-30	Warnings	Exact identifier application number: M018
Optase	GLYCERIN	Scope Health Inc	10c3e31d-779d-8ff6-e063-6294a90acd39	2026-01-30	Warnings	Exact identifier application number: M018
Optase	GLYCERIN	Scope Health Inc	9e96976b-2990-79e0-e053-2995a90a0f29	2026-01-30	Warnings	Exact identifier application number: M018

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
579907	carboxymethylcellulose sodium 1 % Ophthalmic Gel	PSN	4b8b2f6a-4b89-446c-9e5b-9b83c453a01d	8
579907	carboxymethylcellulose sodium 0.01 MG/MG Ophthalmic Gel	SCD	4b8b2f6a-4b89-446c-9e5b-9b83c453a01d	8
579907	carboxymethylcellulose sodium 1 % Ophthalmic Gel	SY	4b8b2f6a-4b89-446c-9e5b-9b83c453a01d	8

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
0023-9205-02	00023920502	2 BOTTLE, DROPPER in 1 CARTON (0023-9205-02) > 15 mL in 1 BOTTLE, DROPPER	2001-10-04	0000-00-00	No	No	Current
0023-9205-03	00023920503	1 BOTTLE, DROPPER in 1 CARTON (0023-9205-03) > 3 mL in 1 BOTTLE, DROPPER	2001-10-04	0000-00-00	No	No	Current
0023-9205-15	00023920515	1 BOTTLE, DROPPER in 1 CARTON (0023-9205-15) / 15 mL in 1 BOTTLE, DROPPER	2001-10-04	0000-00-00	No	No	Current