Acetylcysteine

Product NDC
0143-9433
11-digit product format
001439433
Labeler code
0143
Product ID
0143-9433_9480cdc0-fbc4-411d-b0e8-3d7cf9e9ec7a
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Acetylcysteine
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
Hikma Pharmaceuticals USA Inc.
Application
ANDA217182
Marketing category
ANDA
Marketing start
2026-03-31
Substance
ACETYLCYSTEINE
Active strength
200 mg/mL
Pharmacologic classes
Antidote [EPC], Antidote for Acetaminophen Overdose [EPC], Decreased Respiratory Secretion Viscosity [PE], Increased Glutathione Concentration [PE], Mucolytic [EPC], Reduction Activity [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A217182-001ACETYLCYSTEINEACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-19

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A217182-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-19caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-19011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-1931067a03dcf5…
2025-08-23 18:47 UTC2025-08A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-196a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-19fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-19b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-1903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-192680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-195bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-19d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-19d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-1979d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-19301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-191e350fbaab3a…
2024-05-31 18:47 UTC2024-05A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-198072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-196a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-191c564ffb4f44…
2023-12-20 04:57 UTC2023-12A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-19ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-19a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-199b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-19a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-193f0d92c62455…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217182-001ACETYLCYSTEINE6GM/30ML (200MG/ML)INJECTABLE / INTRAVENOUSAP2023-04-19a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A217182-001AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A217182-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A217182-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A217182-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A217182-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A217182-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A217182-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A217182-001AP12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A217182-001AP15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A217182-001AP1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A217182-001AP1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A217182-001AP179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A217182-001AP1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A217182-001AP11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A217182-001AP18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A217182-001AP16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A217182-001AP11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A217182-001AP1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A217182-001AP1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A217182-001AP19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A217182-001AP1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A217182-001AP13f0d92c62455…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A217182-001AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Acetylcysteine
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ACETYLCYSTEINE200 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
WYQ7N0BPYCInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
465377Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
277963a0-8ab2-4305-a688-28e47e87c584Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
7b19f89e-0a13-4d4e-a994-a46d39d008b9Product name120251120
13c3e0af-2da2-8aec-9e17-1afd680d80c2Product name820221116
f46c867f-cde5-4f14-a7c1-18ae3a6efd1cProduct name120160303

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0143-9433-01Acetylcysteine30 mL in 1 VIALINJECTION, SOLUTION301
0143-9433-04Acetylcysteine4 in 1 CARTONINJECTION, SOLUTION41

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0143-9433-01ML - Milliliter0143-94334025225a-b7ed-4873-a0cd-91301bcaee7c12026-04-20
0143-9433-04ML - Milliliter0143-9433e58fe1da-c605-4e0f-954a-62dbcf75ae0612026-04-20

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
AcetylcysteineACETYLCYSTEINEONESOURCE SPECIALTY PHARMA LIMITED3b0310d2-4e70-4b94-8d69-cb5999a32b542025-09-12Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217182
application number: ANDA217182
AcetylcysteineACETYLCYSTEINEHikma Pharmaceuticals USA Inc.277963a0-8ab2-4305-a688-28e47e87c5842025-09-09Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217182
application number: ANDA217182
ndc (product): 0143-9433
AcetylcysteineACETYLCYSTEINEXellia Pharmaceuticals USA LLC3e2e187e-2445-43b1-b66c-b828e2adf0222023-05-31Warnings, Adverse reactionsExact identifier
application applno (ANDA): 217182
application number: ANDA217182

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
465377acetylcysteine 6 GM in 30 ML InjectionPSN277963a0-8ab2-4305-a688-28e47e87c5841
46537730 ML acetylcysteine 200 MG/ML InjectionSCD277963a0-8ab2-4305-a688-28e47e87c5841
465377acetylcysteine 6 GM per 30 ML InjectionSY277963a0-8ab2-4305-a688-28e47e87c5841

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
0143-9433-010014394330130 mL in 1 VIAL30 mlHistorical
0143-9433-04001439433044 VIAL in 1 CARTON (0143-9433-04) / 30 mL in 1 VIAL (0143-9433-01) 4 vial2026-03-31NoNoCurrent