Cyclosporine

Product NDC
0172-7313
11-digit product format
001727313
Labeler code
0172
Product ID
0172-7313_94a2cdae-e60e-47c4-8bca-8baac9f21b33
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Cyclosporine
Dosage form
SOLUTION
Route
ORAL
Labeler
Teva Pharmaceuticals USA, Inc.
Application
ANDA065078
Marketing category
ANDA
Marketing start
2005-03-29
Substance
CYCLOSPORINE
Active strength
100 mg/mL
Pharmacologic classes
Calcineurin Inhibitor Immunosuppressant [EPC], Calcineurin Inhibitors [MoA], Cytochrome P450 3A4 Inhibitors [MoA], P-Glycoprotein Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A065078-001CYCLOSPORINECYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A065078-001AB1

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 43 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-09-14 22:38:342026-08A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-2584e616aacf4f…
2026-08-18 06:07:402026-07A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-2531067a03dcf5…
2025-08-23 18:47 UTC2025-08A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-256a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-2503ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-252680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-255bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-2579d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-251e350fbaab3a…
2024-05-31 18:47 UTC2024-05A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-258072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-255c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-255d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-254b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-2574a2ff9319b5…
2022-03-09 01:35 UTC2022-03A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-2587673890dc5c…
2021-03-12 10:30 UTC2021-03A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-255aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-258869cabd3fbd…
2020-11-12 02:37 UTC2020-11A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25c0c555d07b60…
2019-12-14 00:12 UTC2019-12A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-253f01610625f2…
2019-09-15 20:21 UTC2019-09A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25b00525d2431f…
2019-07-19 19:46 UTC2019-07A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-256a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-251c564ffb4f44…
2023-12-20 04:57 UTC2023-12A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-259b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-253f0d92c62455…
2023-05-13 08:27 UTC2023-05A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25053a50430f4f…
2023-01-26 05:58 UTC2023-01A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-253bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-253a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A065078-001CYCLOSPORINE100MG/MLSOLUTION / ORALAB12005-03-25f41ea6bd6efb…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 2 · 43 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-09-14 22:38:342026-08A065078-001AB1184e616aacf4f…
2026-08-18 06:07:402026-07A065078-001AB11caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A065078-001AB11011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A065078-001AB1131067a03dcf5…
2025-08-23 18:47 UTC2025-08A065078-001AB116a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A065078-001AB11fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A065078-001AB11b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A065078-001AB1103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A065078-001AB112680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A065078-001AB115bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A065078-001AB11d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A065078-001AB11d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A065078-001AB1179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A065078-001AB11301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A065078-001AB111e350fbaab3a…
2024-05-31 18:47 UTC2024-05A065078-001AB118072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A065078-001AB115c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A065078-001AB115d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A065078-001AB114b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A065078-001AB1174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A065078-001AB11bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A065078-001AB11782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A065078-001AB1187673890dc5c…
2021-03-12 10:30 UTC2021-03A065078-001AB115aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A065078-001AB118869cabd3fbd…
2020-11-12 02:37 UTC2020-11A065078-001AB11c0c555d07b60…
2019-12-14 00:12 UTC2019-12A065078-001AB113f01610625f2…
2019-09-15 20:21 UTC2019-09A065078-001AB11b00525d2431f…
2019-07-19 19:46 UTC2019-07A065078-001AB11ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A065078-001AB116a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A065078-001AB111c564ffb4f44…
2023-12-20 04:57 UTC2023-12A065078-001AB11ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A065078-001AB11a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A065078-001AB119b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A065078-001AB11a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A065078-001AB113f0d92c62455…
2023-05-13 08:27 UTC2023-05A065078-001AB11053a50430f4f…
2023-01-26 05:58 UTC2023-01A065078-001AB113bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A065078-001AB113a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A065078-001AB11f41ea6bd6efb…

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product
Yes
Brand name base
Cyclosporine
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
CYCLOSPORINE100 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
83HN0GTJ6DInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
835886Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
f3dc2a50-1084-4190-a6f3-37034a04db86Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
1be408a0-e15a-4092-b35e-4e294e65196fProduct name320240216
b3fdee3e-0c46-442f-aad5-aa71941d5621Product name120231023
78fb0708-fce5-decd-6611-5a9fbe3e3decProduct name320230327
54840517-000d-4fcb-b976-a6ddd102faa0Product name120220120
a5ba3bd0-8411-4005-ac3b-a41d8ee0633aProduct name120181029
b1c0d609-8b97-06ee-2cd0-5652a4b1d019Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0172-7313-20Cyclosporine1 in 1 PACKAGESOLUTION118
0172-7313-20Cyclosporine50 mL in 1 BOTTLESOLUTION5018

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0172-7313-20ML - Milliliter0172-7313b24be63b-050c-4dfa-8028-8d01ae71267412012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
CYCLOSPORINEACTIVE INGREDIENT83HN0GTJ6DCYCLOSPORINE SOLUTION [IVAX PHARMACEUTICALS, INC.]12
CYCLOSPORINEACTIVE MOIETY83HN0GTJ6DCYCLOSPORINE SOLUTION [IVAX PHARMACEUTICALS, INC.]12
ALCOHOLINACTIVE INGREDIENT3K9958V90MCYCLOSPORINE SOLUTION [IVAX PHARMACEUTICALS, INC.]12
POLYGLYCERYL-10 OLEATEINACTIVE INGREDIENT55C81W76DHCYCLOSPORINE SOLUTION [IVAX PHARMACEUTICALS, INC.]12
POLYGLYCERYL-3 OLEATEINACTIVE INGREDIENTXRQ165498BCYCLOSPORINE SOLUTION [IVAX PHARMACEUTICALS, INC.]12
POLYOXYL 40 HYDROGENATED CASTOR OILINACTIVE INGREDIENT7YC686GQ8FCYCLOSPORINE SOLUTION [IVAX PHARMACEUTICALS, INC.]12

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0172-7313CYCLOSPORINE SOLUTION [TEVA PHARMACEUTICALS USA, INC.]18Current NDC, Legacy NDC, 2 package rows20250502_f3dc2a50-1084-4190-a6f3-37034a04db86.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CyclosporineCYCLOSPORINETeva Pharmaceuticals USA, Inc.f3dc2a50-1084-4190-a6f3-37034a04db862024-07-01Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 065078
application number: ANDA065078
ndc (product): 0172-7313

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
835886cycloSPORINE, modified 100 MG/mL Oral SolutionPSNf3dc2a50-1084-4190-a6f3-37034a04db8618
835886cyclosporine, modified 100 MG/ML Oral SolutionSCDf3dc2a50-1084-4190-a6f3-37034a04db8618

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0172-7313-20001727313201 BOTTLE in 1 PACKAGE (0172-7313-20) / 50 mL in 1 BOTTLE1 bottle2005-03-290000-00-00NoNoCurrent