Cyclosporine

Product NDC
51862-460
11-digit product format
518620460
Labeler code
51862
Product ID
51862-460_2401a70a-8308-4b1b-b1c8-05b91ec230a2
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Cyclosporine
Dosage form
CAPSULE, LIQUID FILLED
Route
ORAL
Labeler
Mayne Pharma Inc.
Application
ANDA065044
Marketing category
ANDA
Marketing start
2016-07-18
Marketing end
0000-00-00
Substance
CYCLOSPORINE
Active strength
100 mg/1
Pharmacologic classes
Calcineurin Inhibitor Immunosuppressant [EPC],Calcineurin Inhibitors [MoA],Cytochrome P450 3A4 Inhibitors [MoA],P-Glycoprotein Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2022-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct51862-460DDiscontinued by firm2026-08-11
excluded packagepackage51862-46051862-460-47DDiscontinued by firm2026-08-11

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A065044-001CYCLOSPORINECYCLOSPORINE100MGCAPSULE / ORALAB12000-12-20
A065044-002CYCLOSPORINECYCLOSPORINE25MGCAPSULE / ORALAB12000-12-20

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A065044-001AB1
A065044-002AB1

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-20011fe1cb6892…
2026-02-19 14:30 UTC2026-02A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-20011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-2031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-2031067a03dcf5…
2025-08-23 18:47 UTC2025-08A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-206a471c1ec25d…
2025-08-23 18:47 UTC2025-08A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-206a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-20fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-20fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-20b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-20b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-2003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-2003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-202680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-202680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-205bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-205bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-20d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-20d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-20d06236e962d9…
2024-10-29 15:01 UTC2024-10A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-20d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-2079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-2079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-20301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-20301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-201e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-201e350fbaab3a…
2024-05-31 18:47 UTC2024-05A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-208072bd15b7f6…
2024-05-31 18:47 UTC2024-05A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-208072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-205c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-205c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-205d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-205d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-204b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-204b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-2074a2ff9319b5…
2019-12-13 00:20 UTC2019-12A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-2074a2ff9319b5…
2022-03-09 01:35 UTC2022-03A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-20bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-20bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A065044-001CYCLOSPORINE100MGCAPSULE / ORALAB12000-12-20782e0a99824c…
2021-12-28 21:50 UTC2021-12A065044-002CYCLOSPORINE25MGCAPSULE / ORALAB12000-12-20782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A065044-001AB11011fe1cb6892…
2026-02-19 14:30 UTC2026-02A065044-002AB11011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A065044-001AB1131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A065044-002AB1131067a03dcf5…
2025-08-23 18:47 UTC2025-08A065044-001AB116a471c1ec25d…
2025-08-23 18:47 UTC2025-08A065044-002AB116a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A065044-001AB11fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A065044-002AB11fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A065044-001AB11b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A065044-002AB11b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A065044-001AB1103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A065044-002AB1103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A065044-001AB112680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A065044-002AB112680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A065044-001AB115bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A065044-002AB115bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A065044-001AB11d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A065044-002AB11d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A065044-001AB11d06236e962d9…
2024-10-29 15:01 UTC2024-10A065044-002AB11d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A065044-001AB1179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A065044-002AB1179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A065044-001AB11301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A065044-002AB11301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A065044-001AB111e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A065044-002AB111e350fbaab3a…
2024-05-31 18:47 UTC2024-05A065044-001AB118072bd15b7f6…
2024-05-31 18:47 UTC2024-05A065044-002AB118072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A065044-001AB115c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A065044-002AB115c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A065044-001AB115d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A065044-002AB115d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A065044-001AB114b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A065044-002AB114b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A065044-001AB1174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A065044-002AB1174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A065044-001AB11bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A065044-002AB11bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A065044-001AB11782e0a99824c…
2021-12-28 21:50 UTC2021-12A065044-002AB11782e0a99824c…

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
1be408a0-e15a-4092-b35e-4e294e65196fProduct name320240216
b3fdee3e-0c46-442f-aad5-aa71941d5621Product name120231023
78fb0708-fce5-decd-6611-5a9fbe3e3decProduct name320230327
54840517-000d-4fcb-b976-a6ddd102faa0Product name120220120
a5ba3bd0-8411-4005-ac3b-a41d8ee0633aProduct name120181029
b1c0d609-8b97-06ee-2cd0-5652a4b1d019Product name120140508

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
51862-460-01EA - Each51862-4601ddf71c7-e5c7-4580-a813-bc2825e872e412016-09-02
51862-460-47EA - Each51862-4600d4f82f2-36b1-4eec-9b57-6ae53053ccbe12016-09-02

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
51862-460CYCLOSPORINE CAPSULE, LIQUID FILLED [MAYNE PHARMA INC.]10Legacy NDC20210918_e7165673-8ab1-4fc8-85e5-a67135af7a7f.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
CyclosporineCYCLOSPORINEDr. Reddy's Laboratories Inc64ec430a-e930-145c-e766-13fb49b646442024-06-03Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (ANDA): 065044
application number: ANDA065044

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
51862-460-475186204604730 BLISTER PACK in 1 BOX (51862-460-47) > 1 CAPSULE, LIQUID FILLED in 1 BLISTER PACK (51862-460-01) 30 blister pack2016-07-180000-00-00NoNoCurrent