Bisoprolol Fumarate and Hydrochlorothiazide

Product NDC: 0185-0707
11-digit product format: 001850707
Labeler code: 0185
Product ID: 0185-0707_a565d200-0d77-4447-b66a-38e344afa792
Type: HUMAN PRESCRIPTION DRUG
Nonproprietary name: Bisoprolol Fumarate and Hydrochlorothiazide
Dosage form: TABLET, COATED
Route: ORAL
Labeler: Eon Labs, Inc.
Application: ANDA075579
Marketing category: ANDA
Marketing start: 2000-09-25
Marketing end: 2021-06-30
Substance: BISOPROLOL FUMARATE; HYDROCHLOROTHIAZIDE
Active strength: 10 mg/1; mg/1
Pharmacologic classes: Adrenergic beta-Antagonists [MoA],beta-Adrenergic Blocker [EPC],Increased Diuresis [PE],Thiazide Diuretic [EPC],Thiazides [CS]
NDC exclude flag: No
Listing certified through: 0000-00-00
Current FDA listing: Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 4 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Source date
excluded product	product	0185-0707		D	Discontinued by firm	2026-10-05
excluded package	package	0185-0707	0185-0707-01	D	Discontinued by firm	2026-10-05
excluded package	package	0185-0707	0185-0707-05	D	Discontinued by firm	2026-10-05
excluded package	package	0185-0707	0185-0707-30	D	Discontinued by firm	2026-10-05

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 48 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source date	Dataset	Scope	Package NDC	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	excluded product	product		`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	0185-0707-05	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	0185-0707-01	`d630ba8d3edf…`	`732f749b63fb…`
2025-12-14 17:58 UTC · source 2025-12-05	excluded package	package	0185-0707-30	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded product	product		`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	0185-0707-05	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	0185-0707-01	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-08-27 00:01 UTC · source 2025-08-26	excluded package	package	0185-0707-30	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded product	product		`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	0185-0707-05	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	0185-0707-01	`2ef7874e63bc…`	`57b86245f4fa…`
2025-04-01 02:39 UTC · source 2025-03-31	excluded package	package	0185-0707-30	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded product	product		`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	0185-0707-05	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	0185-0707-01	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-28 20:22 UTC · source 2025-03-28	excluded package	package	0185-0707-30	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded product	product		`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	0185-0707-05	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	0185-0707-01	`cfe11265f3b6…`	`090c488252e2…`
2025-03-22 03:12 UTC · source 2025-03-21	excluded package	package	0185-0707-30	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded product	product		`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	0185-0707-05	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	0185-0707-01	`cdf11ea48f46…`	`ba0047e9e063…`
2025-03-10 12:48 UTC · source 2025-03-10	excluded package	package	0185-0707-30	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded product	product		`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	0185-0707-05	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	0185-0707-01	`302b2466d912…`	`e7b80fea0513…`
2025-02-02 03:52 UTC · source 2025-01-31	excluded package	package	0185-0707-30	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded product	product		`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	0185-0707-05	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	0185-0707-01	`ed331223b511…`	`672a5bd82f5f…`
2025-01-20 13:05 UTC · source 2025-01-20	excluded package	package	0185-0707-30	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded product	product		`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	0185-0707-05	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	0185-0707-01	`0efc9e666f02…`	`f202fb6c5f17…`
2025-01-11 03:41 UTC · source 2025-01-10	excluded package	package	0185-0707-30	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded product	product		`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	0185-0707-05	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	0185-0707-01	`ad56d346431e…`	`cc804d4bbf1e…`
2024-11-09 02:27 UTC · source 2024-11-08	excluded package	package	0185-0707-30	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded product	product		`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	0185-0707-05	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	0185-0707-01	`367a005e9d99…`	`383a685ebd0f…`
2024-10-04 04:10 UTC · source 2024-10-03	excluded package	package	0185-0707-30	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded product	product		`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	0185-0707-05	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	0185-0707-01	`557ba5c1ecfa…`	`9c80585c8c6e…`
2024-07-10 04:00 UTC · source 2024-07-09	excluded package	package	0185-0707-30	`557ba5c1ecfa…`	`9c80585c8c6e…`

Source provenance: Browse the complete Orange Book source catalog · source snapshot 43.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-product	Trade name	Ingredient	Strength	Dosage form / route	TE codes	Approval date
A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	BISOPROLOL FUMARATE; HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25
A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	BISOPROLOL FUMARATE; HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25
A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	BISOPROLOL FUMARATE; HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 3 matching rows.

Application-product, TE code table
Application-product	TE code
A075579-001	AB
A075579-002	AB
A075579-003	AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 129 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	Trade name	Strength	Dosage form / route	Product TE source text	Approval date	Source SHA-256
2026-09-14 22:38:34	2026-08	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A075579-002	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A075579-003	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	10MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A075579-001	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE	2.5MG;6.25MG	TABLET / ORAL	AB	2000-09-25	`301d65b070ca…`

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 129 observed states.

Captured, Edition, Application-product table
Captured	Edition	Application-product	TE code	Order	Source SHA-256
2026-09-14 22:38:34	2026-08	A075579-001	AB	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	A075579-002	AB	1	`84e616aacf4f…`
2026-09-14 22:38:34	2026-08	A075579-003	AB	1	`84e616aacf4f…`
2026-08-18 06:07:40	2026-07	A075579-001	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A075579-002	AB	1	`caaa826d4ba7…`
2026-08-18 06:07:40	2026-07	A075579-003	AB	1	`caaa826d4ba7…`
2026-02-19 14:30 UTC	2026-02	A075579-001	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A075579-002	AB	1	`011fe1cb6892…`
2026-02-19 14:30 UTC	2026-02	A075579-003	AB	1	`011fe1cb6892…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A075579-001	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A075579-002	AB	1	`31067a03dcf5…`
2025-12-14 10:44 UTC · 2 captures of this ZIP	2025-12	A075579-003	AB	1	`31067a03dcf5…`
2025-08-23 18:47 UTC	2025-08	A075579-001	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A075579-002	AB	1	`6a471c1ec25d…`
2025-08-23 18:47 UTC	2025-08	A075579-003	AB	1	`6a471c1ec25d…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A075579-001	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A075579-002	AB	1	`fd3edfee7708…`
2025-03-22 03:13 UTC · 3 captures of this ZIP	2025-03	A075579-003	AB	1	`fd3edfee7708…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A075579-001	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A075579-002	AB	1	`b8a1b40f171c…`
2025-02-26 10:13 UTC · 3 captures of this ZIP	2025-02	A075579-003	AB	1	`b8a1b40f171c…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A075579-001	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A075579-002	AB	1	`03ed91905a0d…`
2025-01-19 17:59 UTC · 7 captures of this ZIP	2025-01	A075579-003	AB	1	`03ed91905a0d…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A075579-001	AB	1	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A075579-002	AB	1	`2680178bc6a6…`
2024-12-13 21:23 UTC · 2 captures of this ZIP	2024-12	A075579-003	AB	1	`2680178bc6a6…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A075579-001	AB	1	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A075579-002	AB	1	`5bbf6a4d5a75…`
2024-09-14 05:58 UTC · 2 captures of this ZIP	2024-09	A075579-003	AB	1	`5bbf6a4d5a75…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A075579-001	AB	1	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A075579-002	AB	1	`d8e5a09893c0…`
2024-11-08 22:44 UTC · 3 captures of this ZIP	2024-11	A075579-003	AB	1	`d8e5a09893c0…`
2024-10-29 15:01 UTC	2024-10	A075579-001	AB	1	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A075579-002	AB	1	`d06236e962d9…`
2024-10-29 15:01 UTC	2024-10	A075579-003	AB	1	`d06236e962d9…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A075579-001	AB	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A075579-002	AB	1	`79d66fd596c7…`
2024-08-13 05:28 UTC · 3 captures of this ZIP	2024-08	A075579-003	AB	1	`79d66fd596c7…`
2024-07-13 05:37 UTC · 2 captures of this ZIP	2024-07	A075579-001	AB	1	`301d65b070ca…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
c19ec24d-2c40-4b8d-7c20-500ffa3660a1	Product name	3	20260303
97e4a60d-917d-ef62-dc8a-bd557b62b708	Product name	7	20260129
1199f4b7-b537-466c-9a1c-cb09131e9f8b	Product name	1	20251117
e1a63b6e-1877-c2c1-01a3-03ea2817aa6f	Product name	3	20251027
b15e9aa6-d523-ca97-480e-570e0543a342	Product name	4	20251024
96816964-c075-ffa7-b7b8-d8570411a3b9	Product name	7	20250305
162cbc9d-ecc3-72ba-af9f-c76e2756ef54	Product name	3	20221207
9b303cd4-3186-2454-5706-3137e8b2dfd2	Product name	4	20221110
47fc2fe9-7afb-4be9-989d-787aaa6ad0ea	Product name	1	20200505
a8e65197-7914-7acf-c7ec-914d53819b34	Product name	3	20190624
8b67f333-47d1-8464-7ce4-406d3dbb295f	Product name	7	20190618
89a57420-ab44-5323-14f9-595159145f9b	Product name	2	20190612
c27b049d-3258-48cf-ebe5-08c236ae78e2	Product name	3	20190610
00fc2cf9-672f-3e0b-6afa-43cbc864d058	Product name	4	20180613
15b375b1-89c7-9594-80df-5a8c8864aee0	Product name	3	20180108
a7349398-661d-d9fc-46df-7e128bbd61d9	Product name	5	20171113
1bdb87cf-9b1f-6a51-5eb7-d182aaffaa3d	Product name	2	20170719
e0eeb018-194e-4b70-a57d-bac47a97b8ea	Product name	1	20160825
55bffd21-17e1-ff02-2e8f-1f9a532b9502	Product name	2	20150320
ea069444-e874-4c28-833f-d2f52734ef4d	Product name	1	20150206
041df61b-f8b6-48a6-7b67-411e1412678b	Product name	1	20140508
0ad8bdca-888e-00da-648b-6a4de854a167	Product name	1	20140508
433a3439-b8f3-d13a-d2c8-9b221d628d60	Product name	1	20140508
59212689-39e5-a976-6d21-882d76d8079a	Product name	1	20140508
7613b1a5-acb6-4e5e-6048-c44deeeb1212	Product name	1	20140508
78637fb0-95c8-441f-e4b4-db1274b6f956	Product name	1	20140508
df89bd47-2db4-d593-ab37-d11953fd5536	Product name	1	20140508
f151007d-265d-9fbe-857d-1d44f1cb76ba	Product name	1	20140508

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDC	Billing unit	Product NDC	DailyMed indexing SPL	SPL version	Effective
0185-0707-01	EA - Each	0185-0707	41c52c75-d1fc-4af7-bc41-f3227b719e36	1	2012-07-24
0185-0707-05	EA - Each	0185-0707	137aef3a-ba53-4b27-a79c-c1b7700140c5	1	2012-07-24
0185-0707-30	EA - Each	0185-0707	0c37c241-041f-472c-806b-24898a3d9365	1	2012-07-24

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
BISOPROLOL FUMARATE	ACTIVE INGREDIENT	UR59KN573L	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
HYDROCHLOROTHIAZIDE	ACTIVE INGREDIENT	0J48LPH2TH	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
BISOPROLOL	ACTIVE MOIETY	Y41JS2NL6U	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
HYDROCHLOROTHIAZIDE	ACTIVE MOIETY	0J48LPH2TH	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
ANHYDROUS DIBASIC CALCIUM PHOSPHATE	INACTIVE INGREDIENT	L11K75P92J	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
CELLULOSE, MICROCRYSTALLINE	INACTIVE INGREDIENT	OP1R32D61U	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
FD&C RED NO. 40	INACTIVE INGREDIENT	WZB9127XOA	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
FD&C YELLOW NO. 6	INACTIVE INGREDIENT	H77VEI93A8	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
HYPROMELLOSES	INACTIVE INGREDIENT	3NXW29V3WO	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
MAGNESIUM STEARATE	INACTIVE INGREDIENT	70097M6I30	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
POLYETHYLENE GLYCOL	INACTIVE INGREDIENT	3WJQ0SDW1A	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
POLYSORBATE 80	INACTIVE INGREDIENT	6OZP39ZG8H	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
SILICON DIOXIDE	INACTIVE INGREDIENT	ETJ7Z6XBU4	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
STARCH, CORN	INACTIVE INGREDIENT	O8232NY3SJ	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
TITANIUM DIOXIDE	INACTIVE INGREDIENT	15FIX9V2JP	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [EON LABS, INC.]	19
BISOPROLOL FUMARATE	ACTIVE INGREDIENT	UR59KN573L	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
HYDROCHLOROTHIAZIDE	ACTIVE INGREDIENT	0J48LPH2TH	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
BISOPROLOL	ACTIVE MOIETY	Y41JS2NL6U	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
HYDROCHLOROTHIAZIDE	ACTIVE MOIETY	0J48LPH2TH	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
ANHYDROUS DIBASIC CALCIUM PHOSPHATE	INACTIVE INGREDIENT	L11K75P92J	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
CELLULOSE, MICROCRYSTALLINE	INACTIVE INGREDIENT	OP1R32D61U	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
FD&C RED NO. 40	INACTIVE INGREDIENT	WZB9127XOA	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
FD&C YELLOW NO. 6	INACTIVE INGREDIENT	H77VEI93A8	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
HYPROMELLOSES	INACTIVE INGREDIENT	3NXW29V3WO	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
MAGNESIUM STEARATE	INACTIVE INGREDIENT	70097M6I30	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
POLYETHYLENE GLYCOL	INACTIVE INGREDIENT	3WJQ0SDW1A	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
POLYSORBATE 80	INACTIVE INGREDIENT	6OZP39ZG8H	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
SILICON DIOXIDE	INACTIVE INGREDIENT	ETJ7Z6XBU4	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
STARCH, CORN	INACTIVE INGREDIENT	O8232NY3SJ	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
TITANIUM DIOXIDE	INACTIVE INGREDIENT	15FIX9V2JP	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [PHYSICIANS TOTAL CARE, INC.]	2
bisoprolol fumarate	ACTIVE INGREDIENT	UR59KN573L	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
hydrochlorothiazide	ACTIVE INGREDIENT	0J48LPH2TH	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
bisoprolol	ACTIVE MOIETY	Y41JS2NL6U	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
hydrochlorothiazide	ACTIVE MOIETY	0J48LPH2TH	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
ANHYDROUS DIBASIC CALCIUM PHOSPHATE	INACTIVE INGREDIENT	L11K75P92J	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
CELLULOSE, MICROCRYSTALLINE	INACTIVE INGREDIENT	OP1R32D61U	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
FD&C RED NO. 40	INACTIVE INGREDIENT	WZB9127XOA	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
FD&C YELLOW NO. 6	INACTIVE INGREDIENT	H77VEI93A8	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
HYPROMELLOSES	INACTIVE INGREDIENT	3NXW29V3WO	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
magnesium stearate	INACTIVE INGREDIENT	70097M6I30	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
POLYETHYLENE GLYCOL	INACTIVE INGREDIENT	3WJQ0SDW1A	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
POLYSORBATE 80	INACTIVE INGREDIENT	6OZP39ZG8H	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
SILICON DIOXIDE	INACTIVE INGREDIENT	ETJ7Z6XBU4	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
STARCH, CORN	INACTIVE INGREDIENT	O8232NY3SJ	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1
titanium dioxide	INACTIVE INGREDIENT	15FIX9V2JP	BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE TABLET, COATED [REBEL DISTRIBUTORS CORP]	1

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
UR59KN573L	BISOPROLOL FUMARATE	104344-23-2	BISOPROLOL FUMARATE
0J48LPH2TH	HYDROCHLOROTHIAZIDE	58-93-5	HYDROCHLOROTHIAZIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
854908	bisoprolol fumarate 10 MG / hydroCHLOROthiazide 6.25 MG Oral Tablet	PSN	ec524b62-3b42-4c36-bca6-7ef442fcd477	2
854916	bisoprolol fumarate 2.5 MG / hydroCHLOROthiazide 6.25 MG Oral Tablet	PSN	ec524b62-3b42-4c36-bca6-7ef442fcd477	2
854919	bisoprolol fumarate 5 MG / hydroCHLOROthiazide 6.25 MG Oral Tablet	PSN	ec524b62-3b42-4c36-bca6-7ef442fcd477	2
854908	bisoprolol fumarate 10 MG / hydrochlorothiazide 6.25 MG Oral Tablet	SCD	ec524b62-3b42-4c36-bca6-7ef442fcd477	2
854916	bisoprolol fumarate 2.5 MG / hydrochlorothiazide 6.25 MG Oral Tablet	SCD	ec524b62-3b42-4c36-bca6-7ef442fcd477	2
854919	bisoprolol fumarate 5 MG / hydrochlorothiazide 6.25 MG Oral Tablet	SCD	ec524b62-3b42-4c36-bca6-7ef442fcd477	2
854908	bisoprolol fumarate 10 MG / HCTZ 6.25 MG Oral Tablet	SY	ec524b62-3b42-4c36-bca6-7ef442fcd477	2
854916	bisoprolol fumarate 2.5 MG / HCTZ 6.25 MG Oral Tablet	SY	ec524b62-3b42-4c36-bca6-7ef442fcd477	2
854919	bisoprolol fumarate 5 MG / HCTZ 6.25 MG Oral Tablet	SY	ec524b62-3b42-4c36-bca6-7ef442fcd477	2
854908	bisoprolol fumarate 10 MG / hydroCHLOROthiazide 6.25 MG Oral Tablet	PSN	4ae433f5-52bb-4403-984c-32f0fad50dd1	1
854919	bisoprolol fumarate 5 MG / hydroCHLOROthiazide 6.25 MG Oral Tablet	PSN	4ae433f5-52bb-4403-984c-32f0fad50dd1	1
854908	bisoprolol fumarate 10 MG / hydrochlorothiazide 6.25 MG Oral Tablet	SCD	4ae433f5-52bb-4403-984c-32f0fad50dd1	1
854919	bisoprolol fumarate 5 MG / hydrochlorothiazide 6.25 MG Oral Tablet	SCD	4ae433f5-52bb-4403-984c-32f0fad50dd1	1
854908	bisoprolol fumarate 10 MG / HCTZ 6.25 MG Oral Tablet	SY	4ae433f5-52bb-4403-984c-32f0fad50dd1	1
854919	bisoprolol fumarate 5 MG / HCTZ 6.25 MG Oral Tablet	SY	4ae433f5-52bb-4403-984c-32f0fad50dd1	1

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
0185-0707-01	00185070701	100 TABLET, COATED in 1 BOTTLE (0185-0707-01)	2000-09-25	2021-06-30	No	No	Current
0185-0707-30	00185070730	30 TABLET, COATED in 1 BOTTLE (0185-0707-30)	2000-09-25	2021-02-28	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Bisoprolol Fumarate and Hydrochlorothiazide Tablets	Eon Labs, Inc.	2020-09-08	HUMAN PRESCRIPTION DRUG LABEL	22
Bisoprolol Fumarate and Hydrochlorothiazide Tablets	Physicians Total Care, Inc.	2011-12-15	HUMAN PRESCRIPTION DRUG LABEL	2
Bisoprolol Fumarate and Hydrochlorothiazide Tablets, 2.5 mg/6.25 mg, 5 mg/6.25 mg and 10 mg/6.25 mg	Rebel Distributors Corp	2010-12-10	HUMAN PRESCRIPTION DRUG LABEL	1