TROMETHAMINE

Product NDC
0264-8031
11-digit product format
002648031
Labeler code
0264
Product ID
0264-8031_87d30389-4483-4d62-a623-d4676e7d16c9
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
TROMETHAMINE
Dosage form
INJECTION, SOLUTION
Route
INTRAVENOUS
Labeler
B. Braun Medical Inc.
Application
ANDA211558
Marketing category
ANDA
Marketing start
2025-08-27
Substance
TROMETHAMINE
Active strength
3.6 g/100mL
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A211558-001TROMETHAMINETROMETHAMINE18GM/500ML (3.6GM/100ML)SOLUTION / INJECTIONAP2024-12-09

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A211558-001AP

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A211558-001TROMETHAMINE18GM/500ML (3.6GM/100ML)SOLUTION / INJECTIONAP2024-12-09caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211558-001TROMETHAMINE18GM/500ML (3.6GM/100ML)SOLUTION / INJECTIONAP2024-12-09011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211558-001TROMETHAMINE18GM/500ML (3.6GM/100ML)SOLUTION / INJECTIONAP2024-12-0931067a03dcf5…
2025-08-23 18:47 UTC2025-08A211558-001TROMETHAMINE18GM/500ML (3.6GM/100ML)SOLUTION / INJECTIONAP2024-12-096a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211558-001TROMETHAMINE18GM/500ML (3.6GM/100ML)SOLUTION / INJECTIONAP2024-12-09fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211558-001TROMETHAMINE18GM/500ML (3.6GM/100ML)SOLUTION / INJECTIONAP2024-12-09b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211558-001TROMETHAMINE18GM/500ML (3.6GM/100ML)SOLUTION / INJECTIONAP2024-12-0903ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211558-001TROMETHAMINE18GM/500ML (3.6GM/100ML)SOLUTION / INJECTIONAP2024-12-092680178bc6a6…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A211558-001TROMETHAMINE18GM/500ML (3.6GM/100ML)SOLUTION / INJECTIONAP2024-12-09a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A211558-001AP1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A211558-001AP1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211558-001AP131067a03dcf5…
2025-08-23 18:47 UTC2025-08A211558-001AP16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211558-001AP1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211558-001AP1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211558-001AP103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211558-001AP12680178bc6a6…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A211558-001AP1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
TROMETHAMINE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
TROMETHAMINE3.6 g/100mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
023C2WHX2VInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
198412Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
57db5686-7f7f-4999-87e3-e1cbbda4a98dAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
77dc03a4-fbfc-e6a3-fe95-285bbae40d75Product name220250814
48747306-602a-42cc-957b-5b0c69158eeeProduct name120180604
db5ebcdb-b6ae-21cd-4dc5-76cd84b5578bProduct name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0264-8031-10TROMETHAMINE500 mL in 1 BAGINJECTION, SOLUTION5007
0264-8031-10TROMETHAMINE24 in 1 CASEINJECTION, SOLUTION247

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0264-8031-10ML - Milliliter0264-8031f6b08c3f-1044-45a6-a3b3-a1e51c03483212025-09-12

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
TROMETHAMINETROMETHAMINEB. Braun Medical Inc.57db5686-7f7f-4999-87e3-e1cbbda4a98d2024-12-23Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211558
application number: ANDA211558
ndc (product): 0264-8031

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
198412THAM 36 MG/ML in 500 ML InjectionPSN57db5686-7f7f-4999-87e3-e1cbbda4a98d7
198412500 ML tromethamine 36 MG/ML InjectionSCD57db5686-7f7f-4999-87e3-e1cbbda4a98d7
198412tromethamine 18 GM per 500 ML InjectionSY57db5686-7f7f-4999-87e3-e1cbbda4a98d7
198412tromethamine 3.6 GM per 100 ML InjectionSY57db5686-7f7f-4999-87e3-e1cbbda4a98d7

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
0264-8031-100026480311024 BAG in 1 CASE (0264-8031-10) / 500 mL in 1 BAG24 bag2025-08-27NoNoCurrent