Home NDC 0280-0225 Alka-Seltzer Heartburn Plus Gas ReliefChews Tropical Punch
Product NDC 0280-0225
11-digit product format 002800225
Labeler code 0280
Product ID 0280-0225_4cd95f62-f7ef-1ef6-e063-6394a90a4d7e
Type HUMAN OTC DRUG
Nonproprietary name CALCIUM CARBONATE AND SIMETHICONE
Dosage form TABLET, CHEWABLE
Route ORAL
Labeler Bayer HealthCare LLC.
Application M001
Marketing category OTC MONOGRAPH DRUG
Marketing start 2014-03-15
Substance DIMETHICONE; CALCIUM CARBONATE
Active strength 80; 750 mg/1; mg/1
Pharmacologic classes Blood Coagulation Factor [EPC], Calcium [CS], Cations, Divalent [CS], Increased Coagulation Factor Activity [PE], Phosphate Binder [EPC], Phosphate Chelating Activity [MoA], Skin Barrier Activity [PE]
NDC exclude flag No
Listing certified through 2027-12-31
Current FDA listing Yes Reported adverse events (FAERS/openFDA)# Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
Finished product Yes
Brand name base Alka-Seltzer Heartburn Plus Gas ReliefChews Tropical Punch
Listing expiration 2027-12-31 Active Ingredients# Ingredient, Strength table Ingredient Strength DIMETHICONE 80 mg/1 CALCIUM CARBONATE 750 mg/1
Harmonized UNII identifiers# UNII identifiers page 1 of 1 · 2 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 92RU3N3Y1O Internal UNII lookup H0G9379FGK Internal UNII lookup
Harmonized RxCUI identifiers# RxCUI identifiers page 1 of 1 · 1 matching rows.
Identifier, FDA.report destination table Identifier FDA.report destination 1492387 Internal RxNorm lookup
Harmonized SPL set identifiers# SPL set identifiers page 1 of 1 · 1 matching rows.
DailyMed Product Concepts# DailyMed Package Descriptions# Package NDC, Product, Description table Package NDC Product Description Form Quantity Strength SPL version 0280-0225-01 Alka-Seltzer Heartburn Plus Gas ReliefChews Tropical Punch 110 in 1 BOTTLE, PLASTIC TABLET, CHEWABLE 110 8 0280-0225-02 Alka-Seltzer Heartburn Plus Gas ReliefChews Tropical Punch 28 in 1 BOTTLE, PLASTIC TABLET, CHEWABLE 28 8 0280-0225-03 Alka-Seltzer Heartburn Plus Gas ReliefChews Tropical Punch 60 in 1 BOTTLE, PLASTIC TABLET, CHEWABLE 60 8 0280-0225-32 Alka-Seltzer Heartburn Plus Gas ReliefChews Tropical Punch 32 in 1 BOTTLE, PLASTIC TABLET, CHEWABLE 32 8 0280-0225-54 Alka-Seltzer Heartburn Plus Gas ReliefChews Tropical Punch 54 in 1 BOTTLE, PLASTIC TABLET, CHEWABLE 54 8 0280-0225-82 Alka-Seltzer Heartburn Plus Gas ReliefChews Tropical Punch 82 in 1 BOTTLE, PLASTIC TABLET, CHEWABLE 82 8
DailyMed Socrata Ingredients# Ingredient, Type, UNII table Ingredient Type UNII DailyMed label SPL version Uploaded CALCIUM CARBONATE ACTIVE INGREDIENT H0G9379FGK ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 DIMETHICONE ACTIVE INGREDIENT 92RU3N3Y1O ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 CALCIUM CATION ACTIVE MOIETY 2M83C4R6ZB ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 DIMETHICONE ACTIVE MOIETY 92RU3N3Y1O ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 ACACIA INACTIVE INGREDIENT 5C5403N26O ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 aluminum oxide INACTIVE INGREDIENT LMI26O6933 ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 CARNAUBA WAX INACTIVE INGREDIENT R12CBM0EIZ ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 CITRIC ACID MONOHYDRATE INACTIVE INGREDIENT 2968PHW8QP ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 CORN SYRUP INACTIVE INGREDIENT 9G5L16BK6N ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 FD&C red NO. 40 INACTIVE INGREDIENT WZB9127XOA ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 HYDROGENATED COCONUT OIL INACTIVE INGREDIENT JY81OXM1OM ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 MALTODEXTRIN INACTIVE INGREDIENT 7CVR7L4A2D ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 METHYLPARABEN INACTIVE INGREDIENT A2I8C7HI9T ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 POTASSIUM HYDROXIDE INACTIVE INGREDIENT WZH3C48M4T ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 PROPYLENE GLYCOL INACTIVE INGREDIENT 6DC9Q167V3 ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 PROPYLPARABEN INACTIVE INGREDIENT Z8IX2SC1OH ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 SHELLAC INACTIVE INGREDIENT 46N107B71O ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 SORBIC ACID INACTIVE INGREDIENT X045WJ989B ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 SORBITOL INACTIVE INGREDIENT 506T60A25R ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 STARCH, CORN INACTIVE INGREDIENT O8232NY3SJ ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 SUCROSE INACTIVE INGREDIENT C151H8M554 ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 TITANIUM DIOXIDE INACTIVE INGREDIENT 15FIX9V2JP ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 TRIACETIN INACTIVE INGREDIENT XHX3C3X673 ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 WATER INACTIVE INGREDIENT 059QF0KO0R ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1 WHITE WAX INACTIVE INGREDIENT 7G1J5DA97F ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE CONSUMER CARE] 1
DailyMed Dashboard NDC Coverage# NDC, Dashboard title, SPL version table NDC Dashboard title SPL version Validation Dashboard ZIP 0280-0225 ALKA-SELTZER HEARTBURN PLUS GAS RELIEFCHEWS TROPICAL PUNCH (CALCIUM CARBONATE AND SIMETHICONE) TABLET, CHEWABLE [BAYER HEALTHCARE LLC.] 7 Current NDC, Legacy NDC, 6 package rows 20241208_41d17406-3653-4889-81df-6270b7b5d3c7.zip
openFDA label cross-check# OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
Matched openFDA labels page 18 of 34 · 678 matching rows.
Brand, Generic, Manufacturer table Brand Generic Manufacturer SPL set ID Effective date Available safety fields Join Extra Strength Smooth Antacid ANTACID TABLETS Wal-Mart Stores,Inc., 92372491-000d-4273-a668-b87722c1d381 2025-10-27 Warnings Exact identifier application number: M001 equate Extra Strength Smooth Antacid Assorted Berries ANTACID TABLETS Wal-Mart Stores,Inc., cc93e3b4-adbc-4a2c-b6fc-bf7456ef1656 2025-10-27 Warnings Exact identifier application number: M001 Magnesium Oxide MAGNESIUM OXIDE Kesin Pharma 31f417f0-1637-eefa-e063-6294a90a121b 2025-10-27 Warnings Exact identifier application number: M001 Rugby Extra Strength Assorted Berries ANTACID TABLETS Rugby Laboratories b0fcfd66-276e-4741-9aee-915b6364f25c 2025-10-25 Warnings Exact identifier application number: M001 Rugby ANTACID TABLETS Rugby Laboratories 9cb56bc3-7075-4f81-bd10-7e602034b7d8 2025-10-25 Warnings Exact identifier application number: M001 Rugby Cal-Gest Antacid Assorted Flavors ANTACID TABLETS Rugby Laboratories, Inc. a43184c4-d225-4539-b651-4d96535f208f 2025-10-25 Warnings Exact identifier application number: M001 Super vitamin C serum SUPER VITAMIN C FlexiGo Inc 41cbe84e-3ddf-b806-e063-6294a90a55a4 2025-10-22 Warnings Exact identifier application number: M001 Exchange Select Antacid Soft Chews Cherry Flavor CALCIUM CARBONATE Army & Air Force Exchange Service 41ad5581-5b8a-1c8b-e063-6294a90a2ba6 2025-10-21 Warnings Exact identifier application number: M001 Magnesium Oxide MAGNESIUM OXIDE Method Pharmaceuticals, LLC 0af63651-f9d9-43b9-b6f0-4878466a82e6 2025-10-21 Warnings Exact identifier application number: M001 CardinalExtra Strength Antacid Wintergreen flavor CALCIUM CARBONATE CARDINAL HEALTH 4e40989f-c710-442a-bb8d-02e813ddf04d 2025-10-14 Warnings Exact identifier application number: M001 Regular Strength Antacid Assorted Fruit CALCIUM CARBONATE CARDINAL HEALTH def9eaef-308f-49f2-898b-469c2c395d27 2025-10-14 Warnings Exact identifier application number: M001 Leader Extra Strength Sugar Free Antacid ANTACID Cardinal Health d7a6f1b8-bdf7-45bb-bab0-b22f45e78440 2025-10-14 Warnings Exact identifier application number: M001 Extra Strength Antacid Original Flavor ALUMINUM HYDROXIDE AND MAGNESIUM CARBONATE Cardinal Health 1fe459f6-be7f-4c59-b33b-f13ec17071f2 2025-10-14 Warnings Exact identifier application number: M001 Cardinal Extra Strength Smooth Antacid Assorted Fruits CALCIUM CARBONATE CARDINAL HEALTH 84bf7fea-a071-4583-9453-1aea4d198ca6 2025-10-14 Warnings Exact identifier application number: M001 ANTACID Extra Strength CALCIUM CARBONATE Cardinal Health 110, LLC. 3ce9b97b-1680-4299-9a2c-132318adbc0c 2025-10-14 Warnings Exact identifier application number: M001 ANTACID Extra Strength CALCIUM CARBONATE CARDINAL HEALTH 110, LLC. 7c1b2ee6-b691-4c12-bed5-f0a360ad46bb 2025-10-14 Warnings Exact identifier application number: M001 ANTACID Ultra Strength CALCIUM CARBONATE CARDINAL HEALTH 110, LLC. d267ca31-09bd-46d3-be08-a259642f1b7f 2025-10-14 Warnings Exact identifier application number: M001 Magnesium Oxide MAGNESIUM OXIDE A-S Medication Solutions c14d2b4d-d6d8-4293-835e-5d893d5b7e6a 2025-10-10 Warnings Exact identifier application number: M001 Calcium Carbonate Antacid Assorted Berries CALCIUM CARBONATE Xiamen Kang Zhongyuan Biotechnology Co., Ltd. 3f640ccd-4b8d-fc24-e063-6294a90a6e58 2025-09-22 Warnings Exact identifier application number: M001 Stomachin Antacid MAGNESIUM CARBONATE AND SODIUM BICARBONATE Chang Kuo Chou Pharmaceutical Co., Ltd. 60fa0650-8785-4cb3-8f88-1a437296252f 2025-09-19 Warnings Exact identifier application number: M001
DailyMed RxNorm Mappings# Packages# Package NDC, 11-digit format, Description table Package NDC 11-digit format Description Marketing start Marketing end Sample Exclude flag Status 0280-0225-01 00280022501 110 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0225-01) 2020-03-01 0000-00-00 No No Current 0280-0225-02 00280022502 28 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0225-02) 2014-03-15 0000-00-00 No No Current 0280-0225-03 00280022503 60 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0225-03) 2020-03-01 0000-00-00 No No Current 0280-0225-05 00280022505 180 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0225-05) 2020-03-01 No No Current 0280-0225-32 00280022532 32 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0225-32) 2014-03-15 0000-00-00 No No Current 0280-0225-54 00280022554 54 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0225-54) 2014-03-15 0000-00-00 No No Current 0280-0225-82 00280022582 82 TABLET, CHEWABLE in 1 BOTTLE, PLASTIC (0280-0225-82) 2017-03-01 0000-00-00 No No Current