Adapalene and Benzoyl Peroxide

Product NDC
0781-7182
11-digit product format
007817182
Labeler code
0781
Product ID
0781-7182_12b7a31c-65a0-46d4-a655-3015c95b6386
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Adapalene and Benzoyl Peroxide
Dosage form
GEL
Route
TOPICAL
Labeler
Sandoz Inc.
Application
ANDA206164
Marketing category
ANDA
Marketing start
2018-05-23
Marketing end
0000-00-00
Substance
ADAPALENE; BENZOYL PEROXIDE
Active strength
1 mg/g; mg/g
Pharmacologic classes
Retinoid [EPC],Retinoids [CS]
NDC exclude flag
No
Listing certified through
2020-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 3 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct0781-7182DDiscontinued by firm2026-08-03
excluded packagepackage0781-71820781-7182-19DDiscontinued by firm2026-08-03
excluded packagepackage0781-71820781-7182-70DDiscontinued by firm2026-08-03

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 36 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage0781-7182-70d630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage0781-7182-19d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded productproductf5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage0781-7182-70f5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage0781-7182-19f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-31excluded productproduct2ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-31excluded packagepackage0781-7182-702ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-31excluded packagepackage0781-7182-192ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28excluded productproducta1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-28excluded packagepackage0781-7182-70a1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-28excluded packagepackage0781-7182-19a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21excluded productproductcfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-21excluded packagepackage0781-7182-70cfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-21excluded packagepackage0781-7182-19cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10excluded productproductcdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-10excluded packagepackage0781-7182-70cdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-10excluded packagepackage0781-7182-19cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31excluded productproduct302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage0781-7182-70302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage0781-7182-19302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20excluded productproducted331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage0781-7182-70ed331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage0781-7182-19ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-10excluded productproduct0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage0781-7182-700efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage0781-7182-190efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08excluded productproductad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-08excluded packagepackage0781-7182-70ad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-08excluded packagepackage0781-7182-19ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03excluded productproduct367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage0781-7182-70367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage0781-7182-19367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09excluded productproduct557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage0781-7182-70557ba5c1ecfa…9c80585c8c6e…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage0781-7182-19557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A206164-001ADAPALENE AND BENZOYL PEROXIDEADAPALENE; BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-23

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A206164-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 2 · 41 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-23011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-2331067a03dcf5…
2025-08-23 18:47 UTC2025-08A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-236a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-23fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-23b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-2303ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-232680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-235bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-23d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-23d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-2379d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-23301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-231e350fbaab3a…
2024-05-31 18:47 UTC2024-05A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-238072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICAL2018-05-235c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICAL2018-05-235d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICAL2018-05-234b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-2374a2ff9319b5…
2022-03-09 01:35 UTC2022-03A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICAL2018-05-23bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICAL2018-05-23782e0a99824c…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-2387673890dc5c…
2021-03-12 10:30 UTC2021-03A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-235aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-238869cabd3fbd…
2020-11-12 02:37 UTC2020-11A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-23c0c555d07b60…
2019-12-14 00:12 UTC2019-12A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-233f01610625f2…
2019-09-15 20:21 UTC2019-09A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-23b00525d2431f…
2019-07-19 19:46 UTC2019-07A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-23ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-236a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-231c564ffb4f44…
2023-12-20 04:57 UTC2023-12A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-23ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-23a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICALAB2018-05-239b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICAL2018-05-23a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICAL2018-05-233f0d92c62455…
2023-05-13 08:27 UTC2023-05A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICAL2018-05-23053a50430f4f…
2023-01-26 05:58 UTC2023-01A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICAL2018-05-233bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICAL2018-05-233a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICAL2018-05-23f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICAL2018-05-23e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A206164-001ADAPALENE AND BENZOYL PEROXIDE0.1%;2.5%GEL / TOPICAL2018-05-23cb3db0bc1861…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A206164-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A206164-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A206164-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A206164-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A206164-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A206164-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A206164-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A206164-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A206164-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A206164-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A206164-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A206164-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A206164-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A206164-001AB18072bd15b7f6…
2019-12-13 00:20 UTC2019-12A206164-001AB174a2ff9319b5…
2021-05-05 16:15 UTC · 3 captures of this ZIP2021-05A206164-001AB187673890dc5c…
2021-03-12 10:30 UTC2021-03A206164-001AB15aa47cf7b7d7…
2020-12-22 03:56 UTC2020-12A206164-001AB18869cabd3fbd…
2020-11-12 02:37 UTC2020-11A206164-001AB1c0c555d07b60…
2019-12-14 00:12 UTC2019-12A206164-001AB13f01610625f2…
2019-09-15 20:21 UTC2019-09A206164-001AB1b00525d2431f…
2019-07-19 19:46 UTC2019-07A206164-001AB1ea99ee380514…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A206164-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A206164-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A206164-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A206164-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A206164-001AB19b2671bbb829…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A206164-001AB1a50c72e98297…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0781-7182-70GM - Gram0781-7182c3e81b71-bdd5-4bee-ba31-db019354082012018-11-06

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Adapalene and Benzoyl Peroxide Gel, 0.1%/2.5%ADAPALENE AND BENZOYL PEROXIDE GEL, 0.1%/2.5%Encube Ethicals, Inc.66858a82-cfda-4ba9-aac7-cf65499f4b1a2026-06-15Warnings, Adverse reactionsExact identifier
application applno (ANDA): 206164
application number: ANDA206164
Adapalene and Benzoyl Peroxide Gel, 0.1%/2.5%ADAPALENE AND BENZOYL PEROXIDE GEL, 0.1%/2.5%Bryant Ranch Prepack049ea4d9-c60e-4406-b199-da5abe92eced2025-01-08Warnings, Adverse reactionsExact identifier
application applno (ANDA): 206164
application number: ANDA206164

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0781-7182-19007817182191 TUBE in 1 CARTON (0781-7182-19) > 45 g in 1 TUBE1 tube2018-05-230000-00-00NoNoCurrent
0781-7182-70007817182701 BOTTLE, PUMP in 1 CARTON (0781-7182-70) > 45 g in 1 BOTTLE, PUMP2018-05-230000-00-00NoNoCurrent