ADAPALENE AND BENZOYL PEROXIDE

Product NDC
63629-9322
11-digit product format
636299322
Labeler code
63629
Product ID
63629-9322_f679bcb4-f0b3-472f-8df4-a8fd4337eca6
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
adapalene and benzoyl peroxide
Dosage form
GEL
Route
TOPICAL
Labeler
Bryant Ranch Prepack
Application
ANDA212464
Marketing category
ANDA
Marketing start
2022-06-02
Substance
ADAPALENE; BENZOYL PEROXIDE
Active strength
3; 25 mg/g; mg/g
Pharmacologic classes
Retinoid [EPC], Retinoids [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A212464-001ADAPALENE AND BENZOYL PEROXIDEADAPALENE; BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A212464-001AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-3131067a03dcf5…
2025-08-23 18:47 UTC2025-08A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-316a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-3103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-312680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-315bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-3179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-311e350fbaab3a…
2024-05-31 18:47 UTC2024-05A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-318072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-315c6f7cd8ea54…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-316a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-311c564ffb4f44…
2023-12-20 04:57 UTC2023-12A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-319b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-313f0d92c62455…
2023-05-13 08:27 UTC2023-05A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31053a50430f4f…
2023-01-26 05:58 UTC2023-01A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-313bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-313a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A212464-001ADAPALENE AND BENZOYL PEROXIDE0.3%;2.5%GEL / TOPICALAB2022-05-31a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A212464-001AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A212464-001AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A212464-001AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A212464-001AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A212464-001AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A212464-001AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A212464-001AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A212464-001AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A212464-001AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A212464-001AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A212464-001AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A212464-001AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A212464-001AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A212464-001AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A212464-001AB15c6f7cd8ea54…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A212464-001AB16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A212464-001AB11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A212464-001AB1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A212464-001AB1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A212464-001AB19b2671bbb829…
2023-07-15 15:27 UTC · 2 captures of this ZIP2023-07A212464-001AB1a67488948f0b…
2023-06-13 01:57 UTC · 3 captures of this ZIP2023-06A212464-001AB13f0d92c62455…
2023-05-13 08:27 UTC2023-05A212464-001AB1053a50430f4f…
2023-01-26 05:58 UTC2023-01A212464-001AB13bdfa0b2c4d7…
2022-11-12 20:34 UTC · 5 captures of this ZIP2022-11A212464-001AB13a93d1ddd44b…
2022-10-28 04:53 UTC2022-10A212464-001AB1f41ea6bd6efb…
2022-09-29 23:25 UTC2022-09A212464-001AB1e64feba35796…
2022-07-09 03:26 UTC · 3 captures of this ZIP2022-07A212464-001AB1cb3db0bc1861…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A212464-001AB1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
ADAPALENE AND BENZOYL PEROXIDE
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
ADAPALENE3 mg/g
BENZOYL PEROXIDE25 mg/g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1L4806J2QFInternal UNII lookup
W9WZN9A0GMInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
1663745Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
91161d2f-8990-4268-bd74-f60cf33aa2a1Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
a46239a7-5963-4008-8cbb-6b9000f497ebProduct name120250721
b382b4e1-6b48-45f6-bffc-e61b00b0ce19Product name320250317
d9d61457-6a5a-41fc-b418-e5479a2904b7Product name220230303
32012d5c-25ac-49c7-9d4c-1313177fff7cProduct name120230112
13e7e7e3-e885-4c79-af6d-dad1aedbb06eProduct name120220128
4a7d44fe-774d-404b-aad0-8a90fe78375aProduct name420211025
91d0a1ed-5d14-5017-c7aa-3602ee038695Product name320210111
3f45980c-c196-47e5-0e5e-48b7c57327c5Product name520200428
d12e2d7c-bd6b-45d4-94f9-6df8e1b8b27bProduct name320200203
ee5c6de5-d9cd-454f-b250-7b19e5cf2992Product name420190619
ad75fcfd-a339-42a1-9c60-43ba2c654cfaProduct name120170810
5c3dfd42-8936-4261-a420-cfcbbf3030aaProduct name220161206
08f39758-2d46-8afe-73ca-39fe69052a2bProduct name120140508
8ae7bcde-1dd2-b073-852b-f464987f7427Product name120140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
63629-9322-1ADAPALENE AND BENZOYL PEROXIDE45 g in 1 BOTTLE, PUMPGEL45101

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
63629-9322-1GM - Gram63629-9322f900fa82-f18c-4f5c-91f8-03e51d5835e912022-08-04

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
63629-9322ADAPALENE AND BENZOYL PEROXIDE GEL [BRYANT RANCH PREPACK]101Current NDC, Legacy NDC, 1 package rows20240116_91161d2f-8990-4268-bd74-f60cf33aa2a1.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
ADAPALENE AND BENZOYL PEROXIDEADAPALENE AND BENZOYL PEROXIDEBryant Ranch Prepackceae42d9-0264-4a52-a17a-af68b2538ff92024-03-13Warnings, Adverse reactionsExact identifier
application applno (ANDA): 212464
application number: ANDA212464
ADAPALENE AND BENZOYL PEROXIDEADAPALENE AND BENZOYL PEROXIDEBryant Ranch Prepack91161d2f-8990-4268-bd74-f60cf33aa2a12024-01-15Warnings, Adverse reactionsExact identifier
application applno (ANDA): 212464
application number: ANDA212464
ndc (product): 63629-9322
ADAPALENE AND BENZOYL PEROXIDEADAPALENE AND BENZOYL PEROXIDEPadagis Israel Pharmaceuticals Ltd92dcba02-f42f-482d-8cd5-2b5ab8fa540a2022-06-02Warnings, Adverse reactionsExact identifier
application applno (ANDA): 212464
application number: ANDA212464

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1663745adapalene 0.3 % / benzoyl peroxide 2.5 % Topical GelPSN91161d2f-8990-4268-bd74-f60cf33aa2a1101
1663745adapalene 0.003 MG/MG / benzoyl peroxide 0.025 MG/MG Topical GelSCD91161d2f-8990-4268-bd74-f60cf33aa2a1101
1663745adapalene 0.3 % / benzoyl peroxide 2.5 % Topical GelSY91161d2f-8990-4268-bd74-f60cf33aa2a1101

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
63629-9322-16362993220145 g in 1 BOTTLE, PUMP (63629-9322-1) 45 g2022-07-070000-00-00NoNoCurrent