Leucovorin Calcium

Product NDC
0904-7584
11-digit product format
009047584
Labeler code
0904
Product ID
0904-7584_273407f5-0be2-435a-b7a8-f21be8ffbb3c
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Leucovorin Calcium
Dosage form
TABLET
Route
ORAL
Labeler
Major Pharmaceuticals
Application
ANDA211132
Marketing category
ANDA
Marketing start
2026-03-27
Substance
LEUCOVORIN CALCIUM
Active strength
25 mg/1
Pharmacologic classes
Folate Analog [EPC], Folic Acid [CS]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 4 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A211132-001LEUCOVORIN CALCIUMLEUCOVORIN CALCIUMEQ 5MG BASETABLET / ORALAB2020-07-30
A211132-002LEUCOVORIN CALCIUMLEUCOVORIN CALCIUMEQ 10MG BASETABLET / ORALAB2020-07-30
A211132-003LEUCOVORIN CALCIUMLEUCOVORIN CALCIUMEQ 15MG BASETABLET / ORALAB2020-07-30
A211132-004LEUCOVORIN CALCIUMLEUCOVORIN CALCIUMEQ 25MG BASETABLET / ORALABRS2020-07-30

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 4 matching rows.

Application-product, TE code table
Application-productTE code
A211132-001AB
A211132-002AB
A211132-003AB
A211132-004AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 148 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A211132-001LEUCOVORIN CALCIUMEQ 5MG BASETABLET / ORALAB2020-07-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211132-002LEUCOVORIN CALCIUMEQ 10MG BASETABLET / ORALAB2020-07-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211132-003LEUCOVORIN CALCIUMEQ 15MG BASETABLET / ORALAB2020-07-30011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211132-004LEUCOVORIN CALCIUMEQ 25MG BASETABLET / ORALAB2020-07-30011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211132-001LEUCOVORIN CALCIUMEQ 5MG BASETABLET / ORALAB2020-07-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211132-002LEUCOVORIN CALCIUMEQ 10MG BASETABLET / ORALAB2020-07-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211132-003LEUCOVORIN CALCIUMEQ 15MG BASETABLET / ORALAB2020-07-3031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211132-004LEUCOVORIN CALCIUMEQ 25MG BASETABLET / ORALAB2020-07-3031067a03dcf5…
2025-08-23 18:47 UTC2025-08A211132-001LEUCOVORIN CALCIUMEQ 5MG BASETABLET / ORALAB2020-07-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211132-002LEUCOVORIN CALCIUMEQ 10MG BASETABLET / ORALAB2020-07-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211132-003LEUCOVORIN CALCIUMEQ 15MG BASETABLET / ORALAB2020-07-306a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211132-004LEUCOVORIN CALCIUMEQ 25MG BASETABLET / ORALAB2020-07-306a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211132-001LEUCOVORIN CALCIUMEQ 5MG BASETABLET / ORALAB2020-07-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211132-002LEUCOVORIN CALCIUMEQ 10MG BASETABLET / ORALAB2020-07-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211132-003LEUCOVORIN CALCIUMEQ 15MG BASETABLET / ORALAB2020-07-30fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211132-004LEUCOVORIN CALCIUMEQ 25MG BASETABLET / ORALAB2020-07-30fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211132-001LEUCOVORIN CALCIUMEQ 5MG BASETABLET / ORALAB2020-07-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211132-002LEUCOVORIN CALCIUMEQ 10MG BASETABLET / ORALAB2020-07-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211132-003LEUCOVORIN CALCIUMEQ 15MG BASETABLET / ORALAB2020-07-30b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211132-004LEUCOVORIN CALCIUMEQ 25MG BASETABLET / ORALAB2020-07-30b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211132-001LEUCOVORIN CALCIUMEQ 5MG BASETABLET / ORALAB2020-07-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211132-002LEUCOVORIN CALCIUMEQ 10MG BASETABLET / ORALAB2020-07-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211132-003LEUCOVORIN CALCIUMEQ 15MG BASETABLET / ORALAB2020-07-3003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211132-004LEUCOVORIN CALCIUMEQ 25MG BASETABLET / ORALAB2020-07-3003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211132-001LEUCOVORIN CALCIUMEQ 5MG BASETABLET / ORALAB2020-07-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211132-002LEUCOVORIN CALCIUMEQ 10MG BASETABLET / ORALAB2020-07-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211132-003LEUCOVORIN CALCIUMEQ 15MG BASETABLET / ORALAB2020-07-302680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211132-004LEUCOVORIN CALCIUMEQ 25MG BASETABLET / ORALAB2020-07-302680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211132-001LEUCOVORIN CALCIUMEQ 5MG BASETABLET / ORALAB2020-07-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211132-002LEUCOVORIN CALCIUMEQ 10MG BASETABLET / ORALAB2020-07-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211132-003LEUCOVORIN CALCIUMEQ 15MG BASETABLET / ORALAB2020-07-305bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211132-004LEUCOVORIN CALCIUMEQ 25MG BASETABLET / ORALAB2020-07-305bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211132-001LEUCOVORIN CALCIUMEQ 5MG BASETABLET / ORALAB2020-07-30d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211132-002LEUCOVORIN CALCIUMEQ 10MG BASETABLET / ORALAB2020-07-30d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211132-003LEUCOVORIN CALCIUMEQ 15MG BASETABLET / ORALAB2020-07-30d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211132-004LEUCOVORIN CALCIUMEQ 25MG BASETABLET / ORALAB2020-07-30d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211132-001LEUCOVORIN CALCIUMEQ 5MG BASETABLET / ORALAB2020-07-30d06236e962d9…
2024-10-29 15:01 UTC2024-10A211132-002LEUCOVORIN CALCIUMEQ 10MG BASETABLET / ORALAB2020-07-30d06236e962d9…
2024-10-29 15:01 UTC2024-10A211132-003LEUCOVORIN CALCIUMEQ 15MG BASETABLET / ORALAB2020-07-30d06236e962d9…
2024-10-29 15:01 UTC2024-10A211132-004LEUCOVORIN CALCIUMEQ 25MG BASETABLET / ORALAB2020-07-30d06236e962d9…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 4 · 148 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A211132-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211132-002AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211132-003AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A211132-004AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211132-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211132-002AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211132-003AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A211132-004AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A211132-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211132-002AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211132-003AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A211132-004AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211132-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211132-002AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211132-003AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A211132-004AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211132-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211132-002AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211132-003AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A211132-004AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211132-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211132-002AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211132-003AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A211132-004AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211132-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211132-002AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211132-003AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A211132-004AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211132-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211132-002AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211132-003AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A211132-004AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211132-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211132-002AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211132-003AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A211132-004AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A211132-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A211132-002AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A211132-003AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A211132-004AB1d06236e962d9…

Additional Listing Data#

Finished product
Yes
Brand name base
Leucovorin Calcium
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
LEUCOVORIN CALCIUM25 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
RPR1R4C0P4Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
197862Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
273407f5-0be2-435a-b7a8-f21be8ffbb3cAvailable on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
31adef49-84cb-4c51-b122-69e924e10ea3Product name420240827
df40773e-fe5a-474c-8d32-d19c7094e396Product name220240813
cd1aa5b9-18a7-4dc4-8a13-b5c677c859a2Product name120231116
38866763-6a8e-4096-95c3-082a000c243dProduct name120230809
7ce39568-aceb-b33a-23ed-c4964cdcf486Product name220210211
6c712ad1-eecf-448f-84d9-5c0c307a7112Product name120161130

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
0904-7584-10Leucovorin Calcium20 in 1 CARTONTABLET201
0904-7584-10Leucovorin Calcium1 in 1 BLISTER PACKTABLET11

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Leucovorin CalciumLEUCOVORIN CALCIUMMajor Pharmaceuticals273407f5-0be2-435a-b7a8-f21be8ffbb3c2026-03-27Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211132
application number: ANDA211132
ndc (product): 0904-7584
Leucovorin CalciumLEUCOVORIN CALCIUMIngenus Pharmaceuticals, LLC7409cdee-9093-47af-a4c4-2c55ce1b63612026-03-18Warnings, Adverse reactionsExact identifier
application applno (ANDA): 211132
application number: ANDA211132

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
197862leucovorin calcium 25 MG Oral TabletPSN273407f5-0be2-435a-b7a8-f21be8ffbb3c1
197862leucovorin 25 MG Oral TabletSCD273407f5-0be2-435a-b7a8-f21be8ffbb3c1
197862leucovorin 25 MG (as leucovorin calcium 27.01 MG) Oral TabletSY273407f5-0be2-435a-b7a8-f21be8ffbb3c1

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startSampleExclude flagStatus
0904-7584-100090475841020 BLISTER PACK in 1 CARTON (0904-7584-10) / 1 TABLET in 1 BLISTER PACK20 blister pack2026-03-27NoNoCurrent