Leflunomide

Product NDC
0955-1735
11-digit product format
009551735
Labeler code
0955
Product ID
0955-1735_b2fa424f-afd3-47b7-bf2d-44b9f0e88324
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
leflunomide
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
Winthrop U.S.
Application
NDA020905
Marketing category
NDA AUTHORIZED GENERIC
Marketing start
2015-09-07
Marketing end
0000-00-00
Substance
LEFLUNOMIDE
Active strength
10 mg/1
Pharmacologic classes
Antirheumatic Agent [EPC]
NDC exclude flag
No
Listing certified through
2023-12-31
Current FDA listing
Historical FDA.report record

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 2 matching rows.

Dataset, Scope, Product NDC table
DatasetScopeProduct NDCPackage NDCCodeStatusReporting periodSource date
excluded productproduct0955-1735DDiscontinued by firm2026-08-17
excluded packagepackage0955-17350955-1735-30DDiscontinued by firm2026-08-17

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 23 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Dataset, Scope table
Captured / source dateDatasetScopePackage NDCSnapshotSource SHA-256
2025-12-14 17:58 UTC · source 2025-12-05excluded productproductd630ba8d3edf…732f749b63fb…
2025-12-14 17:58 UTC · source 2025-12-05excluded packagepackage0955-1735-30d630ba8d3edf…732f749b63fb…
2025-08-27 00:01 UTC · source 2025-08-26excluded productproductf5e01cc5f278…a2eaf40c39c3…
2025-08-27 00:01 UTC · source 2025-08-26excluded packagepackage0955-1735-30f5e01cc5f278…a2eaf40c39c3…
2025-04-01 02:39 UTC · source 2025-03-31excluded productproduct2ef7874e63bc…57b86245f4fa…
2025-04-01 02:39 UTC · source 2025-03-31excluded packagepackage0955-1735-302ef7874e63bc…57b86245f4fa…
2025-03-28 20:22 UTC · source 2025-03-28excluded productproducta1b67e2a42f9…c4cf2c586c0d…
2025-03-28 20:22 UTC · source 2025-03-28excluded packagepackage0955-1735-30a1b67e2a42f9…c4cf2c586c0d…
2025-03-22 03:12 UTC · source 2025-03-21excluded productproductcfe11265f3b6…090c488252e2…
2025-03-22 03:12 UTC · source 2025-03-21excluded packagepackage0955-1735-30cfe11265f3b6…090c488252e2…
2025-03-10 12:48 UTC · source 2025-03-10excluded productproductcdf11ea48f46…ba0047e9e063…
2025-03-10 12:48 UTC · source 2025-03-10excluded packagepackage0955-1735-30cdf11ea48f46…ba0047e9e063…
2025-02-02 03:52 UTC · source 2025-01-31excluded productproduct302b2466d912…e7b80fea0513…
2025-02-02 03:52 UTC · source 2025-01-31excluded packagepackage0955-1735-30302b2466d912…e7b80fea0513…
2025-01-20 13:05 UTC · source 2025-01-20excluded productproducted331223b511…672a5bd82f5f…
2025-01-20 13:05 UTC · source 2025-01-20excluded packagepackage0955-1735-30ed331223b511…672a5bd82f5f…
2025-01-11 03:41 UTC · source 2025-01-10excluded productproduct0efc9e666f02…f202fb6c5f17…
2025-01-11 03:41 UTC · source 2025-01-10excluded packagepackage0955-1735-300efc9e666f02…f202fb6c5f17…
2024-11-09 02:27 UTC · source 2024-11-08excluded productproductad56d346431e…cc804d4bbf1e…
2024-11-09 02:27 UTC · source 2024-11-08excluded packagepackage0955-1735-30ad56d346431e…cc804d4bbf1e…
2024-10-04 04:10 UTC · source 2024-10-03excluded productproduct367a005e9d99…383a685ebd0f…
2024-10-04 04:10 UTC · source 2024-10-03excluded packagepackage0955-1735-30367a005e9d99…383a685ebd0f…
2024-07-10 04:00 UTC · source 2024-07-09excluded packagepackage0955-1735-30557ba5c1ecfa…9c80585c8c6e…

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 3 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
N020905-001ARAVALEFLUNOMIDE10MGTABLET / ORALABRLD1998-09-10
N020905-002ARAVALEFLUNOMIDE20MGTABLET / ORALABRLD, RS1998-09-10
N020905-003ARAVALEFLUNOMIDE100MGTABLET / ORALRLD1998-09-10

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
N020905-001AB
N020905-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 4 · 126 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-10caaa826d4ba7…
2026-08-18 06:07:402026-07N020905-002ARAVA20MGTABLET / ORALABRLD, RS1998-09-10caaa826d4ba7…
2026-08-18 06:07:402026-07N020905-003ARAVA100MGTABLET / ORALRLD1998-09-10caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N020905-002ARAVA20MGTABLET / ORALABRLD, RS1998-09-10011fe1cb6892…
2026-02-19 14:30 UTC2026-02N020905-003ARAVA100MGTABLET / ORALRLD, RS1998-09-10011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020905-002ARAVA20MGTABLET / ORALABRLD, RS1998-09-1031067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020905-003ARAVA100MGTABLET / ORALRLD, RS1998-09-1031067a03dcf5…
2025-08-23 18:47 UTC2025-08N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N020905-002ARAVA20MGTABLET / ORALABRLD, RS1998-09-106a471c1ec25d…
2025-08-23 18:47 UTC2025-08N020905-003ARAVA100MGTABLET / ORALRLD, RS1998-09-106a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020905-002ARAVA20MGTABLET / ORALABRLD, RS1998-09-10fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020905-003ARAVA100MGTABLET / ORALRLD, RS1998-09-10fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-10b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020905-002ARAVA20MGTABLET / ORALABRLD, RS1998-09-10b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020905-003ARAVA100MGTABLET / ORALRLD, RS1998-09-10b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-1003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020905-002ARAVA20MGTABLET / ORALABRLD, RS1998-09-1003ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020905-003ARAVA100MGTABLET / ORALRLD, RS1998-09-1003ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-102680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020905-002ARAVA20MGTABLET / ORALABRLD, RS1998-09-102680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020905-003ARAVA100MGTABLET / ORALRLD, RS1998-09-102680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-105bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020905-002ARAVA20MGTABLET / ORALABRLD, RS1998-09-105bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020905-003ARAVA100MGTABLET / ORALRLD, RS1998-09-105bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-10d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020905-002ARAVA20MGTABLET / ORALABRLD, RS1998-09-10d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020905-003ARAVA100MGTABLET / ORALRLD, RS1998-09-10d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-10d06236e962d9…
2024-10-29 15:01 UTC2024-10N020905-002ARAVA20MGTABLET / ORALABRLD, RS1998-09-10d06236e962d9…
2024-10-29 15:01 UTC2024-10N020905-003ARAVA100MGTABLET / ORALRLD, RS1998-09-10d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-1079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020905-002ARAVA20MGTABLET / ORALABRLD, RS1998-09-1079d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020905-003ARAVA100MGTABLET / ORALRLD, RS1998-09-1079d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-10301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020905-002ARAVA20MGTABLET / ORALABRLD, RS1998-09-10301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020905-003ARAVA100MGTABLET / ORALRLD, RS1998-09-10301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020905-001ARAVA10MGTABLET / ORALABRLD1998-09-101e350fbaab3a…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 84 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07N020905-001AB1caaa826d4ba7…
2026-08-18 06:07:402026-07N020905-002AB1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02N020905-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02N020905-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020905-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12N020905-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08N020905-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08N020905-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020905-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03N020905-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020905-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02N020905-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020905-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01N020905-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020905-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12N020905-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020905-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09N020905-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020905-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11N020905-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10N020905-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10N020905-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020905-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08N020905-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020905-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07N020905-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020905-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06N020905-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05N020905-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05N020905-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020905-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06N020905-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04N020905-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04N020905-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04N020905-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04N020905-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12N020905-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12N020905-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03N020905-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03N020905-002AB1bb7c543d1eb4…

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
0955-1735-30EA - Each0955-1735306c1a10-15a2-4c13-901c-7496e78b65ae12015-10-02

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
IngredientTypeUNIIDailyMed labelSPL versionUploaded
leflunomideACTIVE INGREDIENTG162GK9U4WLEFLUNOMIDE TABLET, FILM COATED [WINTHROP U.S.]1
leflunomideACTIVE MOIETYG162GK9U4WLEFLUNOMIDE TABLET, FILM COATED [WINTHROP U.S.]1
CrospovidoneINACTIVE INGREDIENT68401960MKLEFLUNOMIDE TABLET, FILM COATED [WINTHROP U.S.]1
FERRIC OXIDE YELLOWINACTIVE INGREDIENTEX438O2MRTLEFLUNOMIDE TABLET, FILM COATED [WINTHROP U.S.]1
hypromellosesINACTIVE INGREDIENT3NXW29V3WOLEFLUNOMIDE TABLET, FILM COATED [WINTHROP U.S.]1
lactose monohydrateINACTIVE INGREDIENTEWQ57Q8I5XLEFLUNOMIDE TABLET, FILM COATED [WINTHROP U.S.]1
magnesium stearateINACTIVE INGREDIENT70097M6I30LEFLUNOMIDE TABLET, FILM COATED [WINTHROP U.S.]1
polyethylene glycolsINACTIVE INGREDIENT3WJQ0SDW1ALEFLUNOMIDE TABLET, FILM COATED [WINTHROP U.S.]1
povidonesINACTIVE INGREDIENTFZ989GH94ELEFLUNOMIDE TABLET, FILM COATED [WINTHROP U.S.]1
SILICON DIOXIDEINACTIVE INGREDIENTETJ7Z6XBU4LEFLUNOMIDE TABLET, FILM COATED [WINTHROP U.S.]1
talcINACTIVE INGREDIENT7SEV7J4R1ULEFLUNOMIDE TABLET, FILM COATED [WINTHROP U.S.]1
titanium dioxideINACTIVE INGREDIENT15FIX9V2JPLEFLUNOMIDE TABLET, FILM COATED [WINTHROP U.S.]1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
0955-1735LEFLUNOMIDE TABLET, FILM COATED [WINTHROP U.S.]13Legacy NDC20240723_eb85de02-2964-453b-978a-26451cd1c97a.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 1 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
AravaLEFLUNOMIDEsanofi-aventis U.S. LLC320f63f2-fac3-4aee-aff8-85724e00ef522025-06-04Boxed warning, Warnings, Adverse reactionsExact identifier
application applno (NDA): 020905
application number: NDA020905

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
0955-1735-30009551735301 BOTTLE in 1 CARTON (0955-1735-30) > 30 TABLET, FILM COATED in 1 BOTTLE1 bottle2015-09-070000-00-00NoNoCurrent