Signature Care Hydrocortisone

Product NDC: 21130-993
11-digit product format: 211300993
Labeler code: 21130
Product ID: 21130-993_2a93d0c8-b2ff-4a3e-9c2b-dcb675498b92
Type: HUMAN OTC DRUG
Nonproprietary name: hydrocortisone
Dosage form: CREAM
Route: TOPICAL
Labeler: Safeway
Application: M017
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2015-11-10
Substance: HYDROCORTISONE
Active strength: 1 g/100g
Pharmacologic classes: Corticosteroid Hormone Receptor Agonists [MoA], Corticosteroid [EPC]
NDC exclude flag: No
Listing certified through: 2026-12-31
Current FDA listing: Yes

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Signature Care Hydrocortisone
Listing expiration: 2026-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
HYDROCORTISONE	1 g/100g

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
WI4X0X7BPJ	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
106258	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
c6b9c4e1-bab8-490d-8c00-c43377ad0857	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
15bd4439-874a-4934-9954-248e5455d460	Product name	1	20260310
9962b773-9f2e-22cc-0032-535e48ac417b	Product name	3	20250724
56bb0587-1bf2-48b2-9d93-fc9f59d1eeb2	Product name	1	20250325
334fe8d2-68fb-4331-a576-420e302ec069	Product name	7	20240320
4d56e8eb-d741-d4a5-de3f-2bab1af75a60	Product name	7	20220608
626d7260-31b5-4412-84fd-579746adb6b3	Product name	1	20210513
8a011600-5e61-4c59-ab7b-54ab658a3b71	Product name	2	20181127
a919621a-248d-3c7a-1084-9f9ce286fdfd	Product name	2	20181009
e7d5a174-836b-a0af-b014-cb0826c69ddc	Product name	2	20181004
fcce390d-6460-4701-87cf-940d8800a1c3	Product name	2	20180212
0441a8f5-3835-497c-aedd-bc78cba56b2a	Product name	1	20150317
bf065fa6-1e3b-e4c3-0bde-2dc842ceeea1	Product name	2	20150218
02657a3f-1489-66ea-f740-5ab9524e57d7	Product name	1	20140508
26f3d783-2cc1-4327-e77d-71804cf675a2	Product name	1	20140508
36fdc54c-bbeb-981e-8a53-4d768e283892	Product name	1	20140508
58f3f9b7-3b9b-a9c1-1c9f-18ac777192b8	Product name	1	20140508
60c52429-fcef-eb54-2387-43bc9e4f296b	Product name	1	20140508
61e59a42-186b-9f4b-aec3-fb49a6debc31	Product name	1	20140508
705740e1-dee5-2610-c5a3-4c59cd9d62af	Product name	1	20140508
7bdc4804-3832-c0df-e519-72b6d47c9792	Product name	1	20140508
a7051cba-790b-a699-81f8-dbbbdbd9b5ac	Product name	1	20140508
abaf203f-619e-f265-559f-8c81af5cb1c2	Product name	1	20140508
acc4d8bb-0e29-e9f8-65f8-31e94184a9c0	Product name	1	20140508
b045ad64-0f28-9a02-2f9b-b34d94fb2278	Product name	1	20140508
bfd28ffb-d550-3fe9-f65b-10bcb7f971fd	Product name	1	20140508
da108d9e-edc8-17a3-8c28-3251c6a8accc	Product name	1	20140508
fe21f3fd-a378-0654-1972-db3c3b64470e	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	Strength	SPL version
21130-993-64	Signature Care Hydrocortisone	1 in 1 CARTON	CREAM	1		4
21130-993-64	Signature Care Hydrocortisone	28 g in 1 TUBE	CREAM	28		4

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
HYDROCORTISONE	ACTIVE INGREDIENT	WI4X0X7BPJ	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
HYDROCORTISONE	ACTIVE MOIETY	WI4X0X7BPJ	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
.ALPHA.-TOCOPHEROL	INACTIVE INGREDIENT	H4N855PNZ1	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
ALOE VERA LEAF	INACTIVE INGREDIENT	ZY81Z83H0X	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
ALUMINUM SULFATE	INACTIVE INGREDIENT	34S289N54E	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
CALCIUM ACETATE	INACTIVE INGREDIENT	Y882YXF34X	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
CETOSTEARYL ALCOHOL	INACTIVE INGREDIENT	2DMT128M1S	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
CETYL ALCOHOL	INACTIVE INGREDIENT	936JST6JCN	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
CHOLECALCIFEROL	INACTIVE INGREDIENT	1C6V77QF41	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
CORN OIL	INACTIVE INGREDIENT	8470G57WFM	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
GLYCERIN	INACTIVE INGREDIENT	PDC6A3C0OX	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
ISOPROPYL PALMITATE	INACTIVE INGREDIENT	8CRQ2TH63M	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
LIGHT MINERAL OIL	INACTIVE INGREDIENT	N6K5787QVP	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
MALTODEXTRIN	INACTIVE INGREDIENT	7CVR7L4A2D	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
METHYLPARABEN	INACTIVE INGREDIENT	A2I8C7HI9T	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
PETROLATUM	INACTIVE INGREDIENT	4T6H12BN9U	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
PROPYLENE GLYCOL	INACTIVE INGREDIENT	6DC9Q167V3	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
PROPYLPARABEN	INACTIVE INGREDIENT	Z8IX2SC1OH	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
SODIUM CETOSTEARYL SULFATE	INACTIVE INGREDIENT	7ZBS06BH4B	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
SODIUM LAURYL SULFATE	INACTIVE INGREDIENT	368GB5141J	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
VITAMIN A PALMITATE	INACTIVE INGREDIENT	1D1K0N0VVC	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
WATER	INACTIVE INGREDIENT	059QF0KO0R	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1
WHITE WAX	INACTIVE INGREDIENT	7G1J5DA97F	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	1

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
21130-993	SIGNATURE CARE HYDROCORTISONE (HYDROCORTISONE) CREAM [SAFEWAY]	4	Current NDC, Legacy NDC, 2 package rows	20241116_c6b9c4e1-bab8-490d-8c00-c43377ad0857.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 101 of 153 · 3,057 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Menthol Pain Relief Gel-Roll On	MENTHOL	Guangzhou Liuquanmiao Import & Export Trade Co., Ltd.	0bd62de8-ce8b-c110-e063-6294a90a98cb	2025-02-07	Warnings	Exact identifier application number: M017
Menthol Pain Relief Gel-Tube	MENTHOL	Guangzhou Liuquanmiao Import & Export Trade Co., Ltd.	0bb07892-824e-8691-e063-6294a90a3891	2025-02-07	Warnings	Exact identifier application number: M017
Olu Pain Management	LIDOCAINE AND CAMPHOR	Olakino Therapeutics LLC	2a41a621-c6f7-5819-e063-6394a90ae67d	2025-02-07	Warnings	Exact identifier application number: M017
Pain Reliveing Patch	LIDOCAINE 4%	simple diagnostics	02ed0b27-bba9-ec0c-e063-6294a90a014d	2025-02-07	Warnings	Exact identifier application number: M017
FlexDermal Pain Relieving Roll-On	MENTHOL	SOLVADERM LLC	d4d8050e-0761-4491-8635-39c806701eb5	2025-02-06	Warnings	Exact identifier application number: M017
Lipo Flavonoid Ear Pain Relief Drops with 4% Lidocaine	LIPO FLAVONOID EAR PAIN RELIEF DROPS WITH 4% LIDOCAINE	Clarion Brands LLC	2d7e9f6a-0f21-b103-e063-6294a90a912f	2025-02-06	Warnings	Exact identifier application number: M017
signature care Hydrocortisone	HYDROCORTISONE	Safeway	9fe16fc5-77e3-47f5-a943-85bc6565c0d4	2025-02-06	Warnings	Exact identifier application number: M017
Methyl Salicylate	METHYL SALICYLATE	PHARMACURE LLC	8803ae01-ea48-46c2-ab64-bb273de605ac	2025-02-05	Warnings	Exact identifier application number: M017
Hempvana Maximum Strength Pain Relief Cream 10% Trolamine Salicylate	TROLAMINE SALICYLATE	TELEBRANDS CORP	2d685602-5cd6-3b36-e063-6394a90a3c5d	2025-02-05	Warnings	Exact identifier application number: M017
Lidocore	LIDOCAINE	iON Pharma, LLC	204c3e50-1ac8-f442-e063-6294a90ae7b5	2025-02-05	Warnings	Exact identifier application number: M017
Methyl Salicylate	METHYL SALICYLATE	PHARMACURE LLC	2c32cfed-2022-4e7c-ae9c-ba22dbb560af	2025-02-04	Warnings	Exact identifier application number: M017
Capsaicin	CAPSAICIN	PHARMACURE LLC	b2b2de93-d957-43d7-a2a8-b46bcaea1f0d	2025-02-04	Warnings	Exact identifier application number: M017
Hempvana Maximum Strength Pain Relief Cream Extreme	MENTHOL 16%, CAMPHOR 11%	Telebrands Corp	2d54077e-4c8d-aaae-e063-6394a90adb41	2025-02-04	Warnings	Exact identifier application number: M017
Capsaicin External Analgesic	CAPSAICIN	NuCare Pharmaceuticals,Inc.	fd90a67d-d60d-a849-e053-6394a90a2cc8	2025-02-04	Warnings	Exact identifier application number: M017
Rugby Muscle Rub Cream	MUSCLE RUB CREAM	NuCare Pharmaceuticals, Inc.	2d58c15a-5ddb-1b16-e063-6294a90a3fbb	2025-02-04	Warnings	Exact identifier application number: M017
Cetilar	MENTHOL 1.4%	PharmaNutra Usa Corp.	2dd14bd4-b4e1-bc7d-e063-6394a90a1e59	2025-02-04	Warnings	Exact identifier application number: M017
Stopain Extra Strength Continuous	MENTHOL	Troy Manufacturing, Inc.	0d199d39-5b47-4c7f-b83a-757f39aa17b6	2025-02-03	Warnings	Exact identifier application number: M017
TheraCare Pain Relieving Lidocaine Cream	LIDOCAINE HYDROCHLORIDE	Veridian Healthcare	2d42192b-8889-a896-e063-6294a90a4fc8	2025-02-03	Warnings	Exact identifier application number: M017
Tiger Balm Pain Relieving Muscle	METHYL SALICYLATE, MENTHOL, UNSPECIFIED FORM, AND CAMPHOR (SYNTHETIC)	Haw Par Healthcare Ltd.	96b06d3f-8685-4314-ad7d-5d2720f4dde6	2025-02-03	Warnings	Exact identifier application number: M017
Icy Hot Medicated No Mess Applicator	MENTHOL	Chattem, Inc.	4ce2b823-7ef5-4cca-a2d8-2fe781bc958e	2025-02-01	Warnings	Exact identifier application number: M017

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
WI4X0X7BPJ	HYDROCORTISONE	50-23-7	HYDROCORTISONE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
106258	hydrocortisone 1 % Topical Cream	PSN	c6b9c4e1-bab8-490d-8c00-c43377ad0857	4
106258	hydrocortisone 10 MG/ML Topical Cream	SCD	c6b9c4e1-bab8-490d-8c00-c43377ad0857	4
106258	hydrocortisone 1 % (as hydrocortisone acetate 1.2 % ) Topical Cream	SY	c6b9c4e1-bab8-490d-8c00-c43377ad0857	4
106258	hydrocortisone 1 % Topical Cream	SY	c6b9c4e1-bab8-490d-8c00-c43377ad0857	4
106258	hydrocortisone 1 GM per 100 GM Topical Cream	SY	c6b9c4e1-bab8-490d-8c00-c43377ad0857	4

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Units	Marketing start	Marketing end	Sample	Exclude flag	Status
21130-993-64	21130099364	1 TUBE in 1 CARTON (21130-993-64) / 28 g in 1 TUBE	1 tube	2015-11-10	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Better Living Brands LLC Hydrocortisone 1% Cream Drug Facts	Safeway	2024-11-15	HUMAN OTC DRUG LABEL	4