Advanced Eye Relief/ Redness Maximum Relief

Product NDC: 24208-450
11-digit product format: 242080450
Labeler code: 24208
Product ID: 24208-450_22f543dc-1475-ff56-e063-6394a90a867b
Type: HUMAN OTC DRUG
Nonproprietary name: Naphazoline Hydrochloride and Hypromellose
Dosage form: SOLUTION/ DROPS
Route: OPHTHALMIC
Labeler: Bausch & Lomb Incorporated
Application: M018
Marketing category: OTC MONOGRAPH DRUG
Marketing start: 2010-09-02
Substance: HYPROMELLOSE, UNSPECIFIED; NAPHAZOLINE HYDROCHLORIDE
Active strength: 5; .3 mg/mL; mg/mL
NDC exclude flag: No
Listing certified through: 2027-12-31
Current FDA listing: Yes

NDC auxiliary status#

These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.

Current NDC status page 1 of 1 · 1 matching rows.

Dataset, Scope, Product NDC table
Dataset	Scope	Product NDC	Package NDC	Code	Status	Reporting period	Source date
excluded package	package	24208-450	24208-450-90	D	Discontinued by firm		2026-10-20

Observed NDC auxiliary status history#

This history shows the information present in each captured FDA auxiliary file. It is not a continuous regulatory timeline, and a missing record does not establish a status.

Historic NDC status page 1 of 1 · 12 matching rows.

View current auxiliary records. · View the auxiliary file history.

Captured / source date, Snapshot, Source SHA-256 table
Captured / source date	Snapshot	Source SHA-256
2025-12-14 17:58 UTC · source 2025-12-05	`d630ba8d3edf…`	`732f749b63fb…`
2025-08-27 00:01 UTC · source 2025-08-26	`f5e01cc5f278…`	`a2eaf40c39c3…`
2025-04-01 02:39 UTC · source 2025-03-31	`2ef7874e63bc…`	`57b86245f4fa…`
2025-03-28 20:22 UTC · source 2025-03-28	`a1b67e2a42f9…`	`c4cf2c586c0d…`
2025-03-22 03:12 UTC · source 2025-03-21	`cfe11265f3b6…`	`090c488252e2…`
2025-03-10 12:48 UTC · source 2025-03-10	`cdf11ea48f46…`	`ba0047e9e063…`
2025-02-02 03:52 UTC · source 2025-01-31	`302b2466d912…`	`e7b80fea0513…`
2025-01-20 13:05 UTC · source 2025-01-20	`ed331223b511…`	`672a5bd82f5f…`
2025-01-11 03:41 UTC · source 2025-01-10	`0efc9e666f02…`	`f202fb6c5f17…`
2024-11-09 02:27 UTC · source 2024-11-08	`ad56d346431e…`	`cc804d4bbf1e…`
2024-10-04 04:10 UTC · source 2024-10-03	`367a005e9d99…`	`383a685ebd0f…`
2024-07-10 04:00 UTC · source 2024-07-09	`557ba5c1ecfa…`	`9c80585c8c6e…`

Reported adverse events (FAERS/openFDA)#

Adverse event summaries are temporarily unavailable. Other product information remains available.

Additional Listing Data#

Finished product: Yes
Brand name base: Advanced Eye Relief/ Redness Maximum Relief
Listing expiration: 2027-12-31

Active Ingredients#

Ingredient, Strength table
Ingredient	Strength
HYPROMELLOSE, UNSPECIFIED	5 mg/mL
NAPHAZOLINE HYDROCHLORIDE	.3 mg/mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
3NXW29V3WO	Internal UNII lookup
MZ1131787D	Internal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
1046654	Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
Identifier	FDA.report destination
3c11285a-7e86-4b47-b1ee-e7d59858087d	Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product concept	Relation	Version	Effective
e18001c8-33ae-5f66-9cdc-a39724bd4573	Product name	1	20140508

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDC	Product	Description	Form	Quantity	SPL version
24208-450-15	Advanced Eye Relief/ Redness Maximum Relief	15 mL in 1 BOTTLE, DROPPER	SOLUTION/ DROPS	15	11
24208-450-15	Advanced Eye Relief/ Redness Maximum Relief	1 in 1 CARTON	SOLUTION/ DROPS	1	11
24208-450-90	Advanced Eye Relief/ Redness Maximum Relief	2 in 1 CARTON	SOLUTION/ DROPS	2	11
24208-450-90	Advanced Eye Relief/ Redness Maximum Relief	15 mL in 1 BOTTLE, DROPPER	SOLUTION/ DROPS	15	11

DailyMed Socrata Ingredients#

Ingredient, Type, UNII table
Ingredient	Type	UNII	DailyMed label	SPL version
HYPROMELLOSES	ACTIVE INGREDIENT	3NXW29V3WO	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
NAPHAZOLINE HYDROCHLORIDE	ACTIVE INGREDIENT	MZ1131787D	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
HYPROMELLOSES	ACTIVE MOIETY	3NXW29V3WO	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
NAPHAZOLINE	ACTIVE MOIETY	H231GF11BV	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
BENZALKONIUM CHLORIDE	INACTIVE INGREDIENT	F5UM2KM3W7	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
BORIC ACID	INACTIVE INGREDIENT	R57ZHV85D4	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
EDETATE DISODIUM	INACTIVE INGREDIENT	7FLD91C86K	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
HYDROCHLORIC ACID	INACTIVE INGREDIENT	QTT17582CB	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
SODIUM BORATE	INACTIVE INGREDIENT	91MBZ8H3QO	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
SODIUM CHLORIDE	INACTIVE INGREDIENT	451W47IQ8X	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
SODIUM HYDROXIDE	INACTIVE INGREDIENT	55X04QC32I	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2
WATER	INACTIVE INGREDIENT	059QF0KO0R	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	2

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDC	Dashboard title	SPL version	Validation	Dashboard ZIP
24208-450	ADVANCED EYE RELIEF/ REDNESS MAXIMUM RELIEF (NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE) SOLUTION/ DROPS [BAUSCH & LOMB INCORPORATED]	11	Current NDC, Legacy NDC, 4 package rows	20240927_3c11285a-7e86-4b47-b1ee-e7d59858087d.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 19 of 25 · 494 matching rows.

Brand, Generic, Manufacturer table
Brand	Generic	Manufacturer	SPL set ID	Effective date	Available safety fields	Join
Eye Wash	WATER	Hubei Changjian Medical Products Co., Ltd.	d57e1c5b-1edc-4a94-88bc-f9ecf347b7ea	2024-10-11	Warnings	Exact identifier application number: M018
Capasil Pain Relieving	MENTHOL, METHYL SALICYLATE	PureTek Corporation	b1a8e78c-57f0-1f3e-e053-2995a90acbd5	2024-10-01	Warnings	Exact identifier application number: M018
Mencylate Pain Relieving	MENTHOL, METHYL SALICYLATE	PureTek Corporation	f824de86-9492-2e6b-e053-6294a90a6f2a	2024-10-01	Warnings	Exact identifier application number: M018
Advanced Eye Relief/ Redness Maximum Relief	NAPHAZOLINE HYDROCHLORIDE AND HYPROMELLOSE	Bausch & Lomb Incorporated	3c11285a-7e86-4b47-b1ee-e7d59858087d	2024-09-25	Warnings	Exact identifier application number: M018 ndc (product): 24208-450
Muro 128	SODIUM CHLORIDE	Bausch & Lomb Incorporated	cc3d5bc8-9d3c-4c65-9e43-707a2db4081a	2024-09-25	Warnings	Exact identifier application number: M018
Muro 128	SODIUM CHLORIDE	Bausch & Lomb Incorporated	93fafa27-5031-4d95-b4b8-5574b7204ae2	2024-09-25	Warnings	Exact identifier application number: M018
Muro 128	SODIUM CHLORIDE	Bausch & Lomb Incorporated	454f337e-d897-46de-ab05-1c543a33061c	2024-09-25	Warnings	Exact identifier application number: M018
PURPOSE	OCTINOXATE, OCTISALATE AND OXYBENZONE	Bausch & Lomb Incorporated	a1e14135-b8da-4cee-8c5b-1893572f4de4	2024-09-25	Warnings	Exact identifier application number: M018
Soothe Night Time	WHITE PETROLATUM MINERAL OIL	Bausch & Lomb Incorporated	638d3c3f-9960-43da-956e-0e28c77f533e	2024-09-24	Warnings	Exact identifier application number: M018
blink tears	POLYETHYLENE GLYCOL 400	Bausch & Lomb Incorporated	10fcf407-6eaf-4730-9ed0-9b7715cf5701	2024-09-20	Warnings	Exact identifier application number: M018
Soothe XP Preservative Free	LIGHT MINERAL OIL AND MINERAL OIL	Bausch & Lomb Incorporated	b254d885-6d49-4c95-b6be-cfdad49c85e6	2024-09-20	Warnings	Exact identifier application number: M018
blink gel tears	POLYETHYLENE GLYCOL 400	Bausch & Lomb Incorporated	6f7e06c3-204d-459a-af8f-c46be9ad0e8d	2024-09-20	Warnings	Exact identifier application number: M018
Soothe XP	LIGHT MINERAL OIL AND MINERAL OIL	Bausch & Lomb Incorporated	c0f053da-8d22-433e-a36e-79cf15ad387f	2024-09-20	Warnings	Exact identifier application number: M018
Soothe	GLYCERIN AND PROPYLENE GLYCOL	Bausch & Lomb Incorporated	fef002ea-c4bd-4486-a42e-1bbd9d73d28d	2024-09-20	Warnings	Exact identifier application number: M018
Leader Preservative-Free Ultra Lubricating Eye Drops	POLYETHYLENE GLYCOL 400, PROPYLENE GLYCOL	Cardinal Health	2a2aa620-ca63-4698-88fd-fc263b8fa0d1	2024-09-07	Warnings	Exact identifier application number: M018
Eyesaline Emergency Eyewash	PURIFIED WATER	Honeywell Safety Products USA, Inc.	ad42a7e3-84ea-390d-e053-2a95a90a3a32	2024-06-14	Warnings	Exact identifier application number: M018
Artificial Tears	POLYVINYL ALCOHOL, POVIDONE	NuCare Pharmaceuticals,Inc.	9c1c4911-908e-3c3c-e053-2995a90abcfc	2024-06-14	Warnings	Exact identifier application number: M018
Eyes Alive Eye Wash	WATER	RIVIERA PHARMA INC	081079f4-1c06-4054-b771-00fedaa666f6	2024-06-05	Warnings	Exact identifier application number: M018
Eyes Alive Lubricating	CARBOXYMETHYLCELLULOSE SODIUM, UNSPECIFIED	RIVIERA PHARMA INC	b6966691-6884-438c-9f89-5924089226e1	2024-05-31	Warnings	Exact identifier application number: M018
Eye Wash	WATER	M-star (Hubei) Health&Care Products Co., Ltd.	71706039-e250-4f08-9687-71b2928c4e46	2024-04-01	Warnings	Exact identifier application number: M018

UNII, Preferred term, Registry number table
UNII	Preferred term	Registry number	Matched term
3NXW29V3WO	HYPROMELLOSE, UNSPECIFIED	9004-65-3	HYPROMELLOSE, UNSPECIFIED
MZ1131787D	NAPHAZOLINE HYDROCHLORIDE	550-99-2	NAPHAZOLINE HYDROCHLORIDE

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUI	RxNorm string	TTY	DailyMed	SPL version
1046654	hypromellose 0.5 % / naphazoline HCl 0.03 % Ophthalmic Solution	PSN	3c11285a-7e86-4b47-b1ee-e7d59858087d	11
1046654	hypromellose 5 MG/ML / naphazoline hydrochloride 0.3 MG/ML Ophthalmic Solution	SCD	3c11285a-7e86-4b47-b1ee-e7d59858087d	11
1046654	hypromellose 0.5 % / naphazoline hydrochloride 0.03 % Ophthalmic Solution	SY	3c11285a-7e86-4b47-b1ee-e7d59858087d	11

Packages#

Package NDC, 11-digit format, Description table
Package NDC	11-digit format	Description	Marketing start	Marketing end	Sample	Exclude flag	Status
24208-450-15	24208045015	1 BOTTLE, DROPPER in 1 CARTON (24208-450-15) / 15 mL in 1 BOTTLE, DROPPER	2010-09-02	0000-00-00	No	No	Current
24208-450-90	24208045090	2 BOTTLE, DROPPER in 1 CARTON (24208-450-90) > 15 mL in 1 BOTTLE, DROPPER	2015-05-01	0000-00-00	No	No	Current

Title, Manufacturer, Effective date table
Title	Manufacturer	Effective date	Type	Version
Drug Facts	Bausch & Lomb Incorporated	2024-09-25	HUMAN OTC DRUG LABEL	11
Drug Facts	Preferred Pharmaceuticals Inc.	2017-06-07	HUMAN OTC DRUG LABEL	1