Demeclocycline Hydrochloride

Product NDC
24658-710
11-digit product format
246580710
Labeler code
24658
Product ID
24658-710_aa40e353-18db-4553-8f8d-a434eac8ed1f
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Demeclocycline Hydrochloride
Dosage form
TABLET, FILM COATED
Route
ORAL
Labeler
PuraCap Laboratories LLC
Application
ANDA065447
Marketing category
ANDA
Marketing start
2017-10-07
Substance
DEMECLOCYCLINE HYDROCHLORIDE
Active strength
150 mg/1
Pharmacologic classes
Tetracycline-class Antimicrobial [EPC], Tetracyclines [CS]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 1.

Orange Book products#

Current product rows page 1 of 1 · 2 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A065447-001DEMECLOCYCLINE HYDROCHLORIDEDEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-18
A065447-002DEMECLOCYCLINE HYDROCHLORIDEDEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-18

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 2 matching rows.

Application-product, TE code table
Application-productTE code
A065447-001AB
A065447-002AB

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Product history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-02-19 14:30 UTC2026-02A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-18011fe1cb6892…
2026-02-19 14:30 UTC2026-02A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-18011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-1831067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-1831067a03dcf5…
2025-08-23 18:47 UTC2025-08A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-186a471c1ec25d…
2025-08-23 18:47 UTC2025-08A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-186a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-18fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-18fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-18b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-18b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-1803ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-1803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-182680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-182680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-185bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-185bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-18d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-18d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-18d06236e962d9…
2024-10-29 15:01 UTC2024-10A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-18d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-1879d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-1879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-18301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-18301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-181e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-181e350fbaab3a…
2024-05-31 18:47 UTC2024-05A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-188072bd15b7f6…
2024-05-31 18:47 UTC2024-05A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-188072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-185c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-185c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-185d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-185d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-184b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-184b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-1874a2ff9319b5…
2019-12-13 00:20 UTC2019-12A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-1874a2ff9319b5…
2022-03-09 01:35 UTC2022-03A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-18bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-18bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A065447-001DEMECLOCYCLINE HYDROCHLORIDE150MGTABLET / ORALAB2015-08-18782e0a99824c…
2021-12-28 21:50 UTC2021-12A065447-002DEMECLOCYCLINE HYDROCHLORIDE300MGTABLET / ORALAB2015-08-18782e0a99824c…

Observed Orange Book normalized TE history#

Normalized TE history page 1 of 3 · 82 observed states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-02-19 14:30 UTC2026-02A065447-001AB1011fe1cb6892…
2026-02-19 14:30 UTC2026-02A065447-002AB1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A065447-001AB131067a03dcf5…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A065447-002AB131067a03dcf5…
2025-08-23 18:47 UTC2025-08A065447-001AB16a471c1ec25d…
2025-08-23 18:47 UTC2025-08A065447-002AB16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A065447-001AB1fd3edfee7708…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A065447-002AB1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A065447-001AB1b8a1b40f171c…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A065447-002AB1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A065447-001AB103ed91905a0d…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A065447-002AB103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A065447-001AB12680178bc6a6…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A065447-002AB12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A065447-001AB15bbf6a4d5a75…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A065447-002AB15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A065447-001AB1d8e5a09893c0…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A065447-002AB1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A065447-001AB1d06236e962d9…
2024-10-29 15:01 UTC2024-10A065447-002AB1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A065447-001AB179d66fd596c7…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A065447-002AB179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A065447-001AB1301d65b070ca…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A065447-002AB1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A065447-001AB11e350fbaab3a…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A065447-002AB11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A065447-001AB18072bd15b7f6…
2024-05-31 18:47 UTC2024-05A065447-002AB18072bd15b7f6…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A065447-001AB15c6f7cd8ea54…
2022-06-29 02:47 UTC · 2 captures of this ZIP2022-06A065447-002AB15c6f7cd8ea54…
2022-04-08 23:34 UTC2022-04A065447-001AB15d02ea3f76ae…
2022-04-08 23:34 UTC2022-04A065447-002AB15d02ea3f76ae…
2022-04-04 05:41 UTC2022-04A065447-001AB14b0b4de00fa7…
2022-04-04 05:41 UTC2022-04A065447-002AB14b0b4de00fa7…
2019-12-13 00:20 UTC2019-12A065447-001AB174a2ff9319b5…
2019-12-13 00:20 UTC2019-12A065447-002AB174a2ff9319b5…
2022-03-09 01:35 UTC2022-03A065447-001AB1bb7c543d1eb4…
2022-03-09 01:35 UTC2022-03A065447-002AB1bb7c543d1eb4…
2021-12-28 21:50 UTC2021-12A065447-001AB1782e0a99824c…
2021-12-28 21:50 UTC2021-12A065447-002AB1782e0a99824c…

Additional Listing Data#

Finished product
Yes
Brand name base
Demeclocycline Hydrochloride
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
DEMECLOCYCLINE HYDROCHLORIDE150 mg/1

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
29O079NTYTInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 2 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
905341Internal RxNorm lookup
905347Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
88e03cb0-25f5-41a5-b77f-58ab8f3be181Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
b5dbb1ae-e36f-978d-e5e0-8711031739bcProduct name220150904

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
24658-710-01Demeclocycline Hydrochloride100 in 1 BOTTLETABLET, FILM COATED1006

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
24658-710-01EA - Each24658-710e438abe1-3e2e-47b8-99ba-b643c706731612018-08-13

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
24658-710DEMECLOCYCLINE HYDROCHLORIDE TABLET, FILM COATED [PURACAP LABORATORIES LLC]5Current NDC, Legacy NDC, 1 package rows20241222_88e03cb0-25f5-41a5-b77f-58ab8f3be181.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 2 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
Demeclocycline HydrochlorideDEMECLOCYCLINE HYDROCHLORIDEPuraCap Laboratories LLC88e03cb0-25f5-41a5-b77f-58ab8f3be1812025-12-11Warnings, Adverse reactionsExact identifier
application applno (ANDA): 065447
application number: ANDA065447
ndc (product): 24658-710
Demeclocycline HydrochlorideDEMECLOCYCLINE HYDROCHLORIDEEpic Pharma, LLC645af8f4-0843-4afb-9ddc-f587f38adb682023-11-08Warnings, Adverse reactionsExact identifier
application applno (ANDA): 065447
application number: ANDA065447

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
905341demeclocycline HCl 150 MG Oral TabletPSN88e03cb0-25f5-41a5-b77f-58ab8f3be1816
905347demeclocycline HCl 300 MG Oral TabletPSN88e03cb0-25f5-41a5-b77f-58ab8f3be1816
905341demeclocycline hydrochloride 150 MG Oral TabletSCD88e03cb0-25f5-41a5-b77f-58ab8f3be1816
905347demeclocycline hydrochloride 300 MG Oral TabletSCD88e03cb0-25f5-41a5-b77f-58ab8f3be1816

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startMarketing endSampleExclude flagStatus
24658-710-0124658071001100 TABLET, FILM COATED in 1 BOTTLE (24658-710-01) 2017-10-070000-00-00NoNoCurrent