Crest Pro-Health Multi-Protection
- Product NDC
- 37000-451
- 11-digit product format
- 370000451
- Labeler code
- 37000
- Product ID
- 37000-451_47e4e758-d6de-4e88-e063-6394a90ac40e
- Type
- HUMAN OTC DRUG
- Nonproprietary name
- Cetylpyridinium chloride
- Dosage form
- RINSE
- Route
- ORAL
- Labeler
- The Procter & Gamble Manufacturing Company
- Application
- M022
- Marketing category
- OTC MONOGRAPH DRUG
- Marketing start
- 2011-02-03
- Substance
- CETYLPYRIDINIUM CHLORIDE
- Active strength
- .014 g/20mL
- NDC exclude flag
- No
- Listing certified through
- 2027-12-31
- Current FDA listing
- Yes
NDC auxiliary status#
These records are reproduced from FDA’s unfinished, excluded, and compounder listings. They describe what appeared in the source files; a missing record does not establish a regulatory status. View all current auxiliary records, including entries without an NDC. · View the auxiliary file history.
| Dataset | Scope | Product NDC | Package NDC | Code | Status | Reporting period | Source date |
|---|---|---|---|---|---|---|---|
| excluded package | package | 37000-451 | 37000-451-10 | D | Discontinued by firm | 2026-10-15 |
Reported adverse events (FAERS/openFDA)#
Adverse event summaries are temporarily unavailable. Other product information remains available.
Additional Listing Data#
- Finished product
- Yes
- Brand name base
- Crest Pro-Health Multi-Protection
- Brand name suffix
- Refreshing Clean Mint
- Listing expiration
- 2027-12-31
Active Ingredients#
| Ingredient | Strength |
|---|---|
| CETYLPYRIDINIUM CHLORIDE | .014 g/20mL |
Harmonized UNII identifiers#
| Identifier | FDA.report destination |
|---|---|
| D9OM4SK49P | Internal UNII lookup |
Harmonized RxCUI identifiers#
Harmonized SPL set identifiers#
| Identifier | FDA.report destination |
|---|---|
| 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | Available on FDA.report |
FDA-Initiated Inactive NDC Indexing#
DailyMed Package Descriptions#
| Package NDC | Product | Description | Form | Quantity | Strength | SPL version |
|---|---|---|---|---|---|---|
| 37000-451-01 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 36 mL in 1 BOTTLE, PLASTIC | RINSE | 36 | 14 | |
| 37000-451-02 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 100 mL in 1 BOTTLE, PLASTIC | RINSE | 100 | 14 | |
| 37000-451-03 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 250 mL in 1 BOTTLE, PLASTIC | RINSE | 250 | 14 | |
| 37000-451-04 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 500 mL in 1 BOTTLE, PLASTIC | RINSE | 500 | 14 | |
| 37000-451-05 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 1000 mL in 1 BOTTLE, PLASTIC | RINSE | 1000 | 14 | |
| 37000-451-06 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 1500 mL in 1 BOTTLE, PLASTIC | RINSE | 1500 | 14 | |
| 37000-451-10 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 2 in 1 PACKAGE | RINSE | 2 | 14 | |
| 37000-451-10 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 1000 mL in 1 BOTTLE | RINSE | 1000 | 14 | |
| 37000-451-11 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 3 in 1 CELLO PACK | RINSE | 3 | 14 | |
| 37000-451-11 | Crest Pro-Health Multi-ProtectionRefreshing Clean Mint | 1000 mL in 1 BOTTLE, PLASTIC | RINSE | 1000 | 14 |
DailyMed Socrata Ingredients#
DailyMed Dashboard NDC Coverage#
| NDC | Dashboard title | SPL version | Validation | Dashboard ZIP |
|---|---|---|---|---|
| 37000-451 | CREST PRO-HEALTH MULTI-PROTECTION REFRESHING CLEAN MINT (CETYLPYRIDINIUM CHLORIDE) RINSE [THE PROCTER & GAMBLE MANUFACTURING COMPANY] | 11 | Current NDC, Legacy NDC, 10 package rows | 20250309_8867d791-7e93-4f39-aaaf-bfbee8296fd9.zip |
openFDA label cross-check#
OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.
| Brand | Generic | Manufacturer | SPL set ID | Effective date | Available safety fields | Join |
|---|---|---|---|---|---|---|
| Listerine Gum Therapy Glacier Mint | EUCALYPTOL, MENTHOL, METHYL SALICYLATE, THYMOL | Kenvue Brands LLC | ed6889b6-58db-41cf-e053-2a95a90a7de2 | 2024-11-11 | Warnings | M022 |
| Listerine FreshBurst Antiseptic | EUCALYPTOL, MENTHOL, UNSPECIFIED FORM, METHYL SALICYLATE, AND THYMOL | Kenvue Brands LLC | 62b5c3ee-01cc-4c4e-9f28-e7dafa7372d8 | 2024-11-11 | Warnings | M022 |
| Listerine Ultraclean Antiseptic Cool Mint | EUCALYPTOL, MENTHOL, UNSPECIFIED FORM, METHYL SALICYLATE, AND THYMOL | Kenvue Brands LLC | dd3729c2-fd05-4db0-a542-487bb0f9001f | 2024-11-11 | Warnings | M022 |
| Listerine Cool Mint Antiseptic | EUCALYPTOL, MENTHOL, UNSPECIFIED FORM, METHYL SALICYLATE, AND THYMOL | Kenvue Brands LLC | 9e97e4f8-80c2-44e0-862c-0dfca392a436 | 2024-11-11 | Warnings | M022 |
| Orajel 2X Medicated Gel | ORAL PAIN RELIEVER | Church & Dwight Co., Inc. | 262be295-4eaf-3136-e063-6294a90a7dcc | 2024-11-05 | Warnings | M022 |
| BIOTENE Fresh Mint Original | SODIUM FLUORIDE | Haleon US Holdings LLC | 1101c17f-c848-4cd5-a7cd-679b59dbe1bf | 2024-11-05 | Warnings | M022 |
| biotene | SODIUM MONOFLUOROPHOSPHATE | Haleon US Holdings LLC | a47a6502-efb2-4072-9562-cbe293531c2b | 2024-11-04 | Warnings | M022 |
| Amosan Oral Wound Cleanser Cherry | SODIUM PERBORATE MONOHYDRATE | Vintage Brands Limited | a0e145c8-6b08-40be-ae4f-5678c4a78b1e | 2024-10-30 | Warnings | M022 |
| HurriCaine Topical Anesthetic | BENZOCAINE | Beutlich Pharmaceuticals, LLC | 043bfbc3-c33b-78b7-e063-6294a90a1a5a | 2024-10-29 | Warnings | M022 |
| HurriCaine Topical Anesthetic | BENZOCAINE | Beutlich Pharmaceuticals, LLC | 043bfbc3-c33a-78b7-e063-6294a90a1a5a | 2024-10-29 | Warnings | M022 |
| HurriCaine Topical Anesthetic | BENZOCAINE | Beutlich Pharmaceuticals, LLC | 043a3cb4-f560-0ffd-e063-6394a90a2ff6 | 2024-10-29 | Warnings | M022 |
| Amosan Oral Wound Cleanser Mint | SODIUM PERBORATE MONOHYDRATE | Vintage Brands Limited | be57ca56-834f-4170-a407-f193484d8b0a | 2024-10-29 | Warnings | M022 |
| SENSODYNE PRONAMEL Intensive Enamel Repair Clean Mint | SODIUM FLUORIDE | Haleon US Holdings LLC | 817c0dad-d109-428e-adb5-3354604acc94 | 2024-10-28 | Warnings | M022 |
| HurriCaine Topical Anesthetic | BENZOCAINE | Beutlich Pharmaceuticals, LLC | 1f3d68f6-afd6-42e7-b3e5-210228c8e7de | 2024-10-28 | Warnings | M022 |
| HurriCaine Topical Anesthetic | BENZOCAINE | Beutlich Pharmaceuticals LLC | 0dd15227-6603-42ac-9a5f-f2dc49e0382a | 2024-10-28 | Warnings, Adverse reactions | M022 |
| HurriCaine Topical Anesthetic | BENZOCAINE | Beutlich Pharmaceuticals, LLC | 0605d5d6-82bd-415e-b5cb-e273f934a4a7 | 2024-10-28 | Warnings | M022 |
| HurriCaine Topical Anesthetic Liquid | BENZOCAINE | Beutlich Pharmaceuticals, LLC | f70fa3fc-cd65-4a80-9efd-129e98fd3998 | 2024-10-28 | Warnings | M022 |
| Sore Throat Relief Menthol | PHENOL | Chain Drug Consortium | af661ef0-cdc3-4146-8ae5-59795aa49650 | 2024-10-28 | Warnings | M022 |
| Sore Throat Relief Cherry Flavor | PHENOL | Chain Drug Consortium | a9cf9829-4b70-44fa-9719-240b65c06724 | 2024-10-28 | Warnings | M022 |
| Ear Wax Removal Aid Drops | CARBAMIDE PEROXIDE | PHARMACY VALUE ALLIANCE, LLC | 85ae80c1-2bc2-4c90-9559-63510d03e739 | 2024-10-28 | Warnings | M022 |
DailyMed RxNorm Mappings#
| RxCUI | RxNorm string | TTY | DailyMed | SPL version |
|---|---|---|---|---|
| 1100924 | cetylpyridinium chloride 0.07 % Oral Rinse | PSN | 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | 14 |
| 1251371 | Crest Pro-Health 0.07 % Oral Rinse | PSN | 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | 14 |
| 1251371 | cetylpyridinium chloride 0.7 MG/ML Mouthwash [Crest Mouthwash] | SBD | 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | 14 |
| 1100924 | cetylpyridinium chloride 0.7 MG/ML Mouthwash | SCD | 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | 14 |
| 1100924 | cetylpyridinium chloride 0.07 % Oral Rinse | SY | 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | 14 |
| 1251371 | Crest 0.07 % Mouthwash | SY | 8867d791-7e93-4f39-aaaf-bfbee8296fd9 | 14 |
| 1100924 | cetylpyridinium chloride 0.07 % Oral Rinse | PSN | 65bf17a9-21ad-27cb-e053-2991aa0afc40 | 4 |
| 1251371 | Crest Pro-Health 0.07 % Oral Rinse | PSN | 65bf17a9-21ad-27cb-e053-2991aa0afc40 | 4 |
| 1251371 | cetylpyridinium chloride 0.7 MG/ML Mouthwash [Crest Mouthwash] | SBD | 65bf17a9-21ad-27cb-e053-2991aa0afc40 | 4 |
| 1100924 | cetylpyridinium chloride 0.7 MG/ML Mouthwash | SCD | 65bf17a9-21ad-27cb-e053-2991aa0afc40 | 4 |
| 1100924 | cetylpyridinium chloride 0.07 % Oral Rinse | SY | 65bf17a9-21ad-27cb-e053-2991aa0afc40 | 4 |
| 1251371 | Crest 0.07 % Mouthwash | SY | 65bf17a9-21ad-27cb-e053-2991aa0afc40 | 4 |
Packages#
| Package NDC | 11-digit format | Description | Units | Marketing start | Marketing end | Sample | Exclude flag | Status |
|---|---|---|---|---|---|---|---|---|
| 37000-451-01 | 37000045101 | 36 mL in 1 BOTTLE, PLASTIC (37000-451-01) | 36 ml | 2011-02-03 | 0000-00-00 | No | No | Current |
| 37000-451-02 | 37000045102 | 100 mL in 1 BOTTLE, PLASTIC (37000-451-02) | 100 ml | 2021-01-01 | 0000-00-00 | No | No | Current |
| 37000-451-03 | 37000045103 | 250 mL in 1 BOTTLE, PLASTIC (37000-451-03) | 250 ml | 2011-02-03 | 0000-00-00 | No | No | Current |
| 37000-451-04 | 37000045104 | 500 mL in 1 BOTTLE, PLASTIC (37000-451-04) | 500 ml | 2011-02-03 | 0000-00-00 | No | No | Current |
| 37000-451-05 | 37000045105 | 1000 mL in 1 BOTTLE, PLASTIC (37000-451-05) | 1000 ml | 2011-02-03 | 0000-00-00 | No | No | Current |
| 37000-451-06 | 37000045106 | 1500 mL in 1 BOTTLE, PLASTIC (37000-451-06) | 1500 ml | 2011-02-03 | 0000-00-00 | No | No | Current |
| 37000-451-10 | 37000045110 | 2 BOTTLE in 1 PACKAGE (37000-451-10) > 1000 mL in 1 BOTTLE | 2 bottle | 2011-02-03 | 0000-00-00 | No | No | Current |
| 37000-451-11 | 37000045111 | 3 BOTTLE, PLASTIC in 1 CELLO PACK (37000-451-11) / 1000 mL in 1 BOTTLE, PLASTIC | 2011-02-03 | No | No | Current |