Cinryze

Product NDC
42227-081
11-digit product format
422270081
Labeler code
42227
Product ID
42227-081_421ea216-278f-4ca8-ae5d-5dafe85658a0
Type
PLASMA DERIVATIVE
Nonproprietary name
HUMAN C1-ESTERASE INHIBITOR
Dosage form
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
Route
INTRAVENOUS
Labeler
Takeda Pharmaceuticals America, Inc.
Application
BLA125267
Marketing category
BLA
Marketing start
2008-12-01
Substance
HUMAN C1-ESTERASE INHIBITOR
Active strength
500 [iU]/5mL
Pharmacologic classes
Decreased Vascular Permeability [PE], Human C1 Esterase Inhibitor [EPC], Kallikrein Inhibitors [MoA]
NDC exclude flag
No
Listing certified through
2026-12-31
Current FDA listing
Yes

Additional Listing Data#

Finished product
Yes
Brand name base
Cinryze
Listing expiration
2026-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
HUMAN C1-ESTERASE INHIBITOR500 [iU]/5mL

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
0ca1d589-929b-4b33-bc5b-1d84abdafa6aProduct name120150324
fc363c46-397b-4476-ac0f-70e43e8e4592Product name120150324

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
42227-081-01Cinryze5 mL in 1 VIAL, SINGLE-USEINJECTION, POWDER, LYOPHILIZED,5 mL500 [iU] in 5mL42
42227-081-01Cinryze5 mL in 1 VIAL, SINGLE-USEINJECTION, POWDER, LYOPHILIZED,542

DailyMed Billing Units#

Package NDC, Billing unit, Product NDC table
Package NDCBilling unitProduct NDCDailyMed indexing SPLSPL versionEffective
42227-081-01EA - Each42227-0817bf10b10-62fa-41ad-8142-ba8838d224fd12018-11-06
42227-081-05EA - Each42227-081aab4b7ce-bd70-40c0-b0ad-67d71fb816a212012-07-24

DailyMed Socrata Ingredients#

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
42227-081CINRYZE (HUMAN C1-ESTERASE INHIBITOR) INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION CINRYZE (HUMAN C1-ESTERASE INHIBITOR) KIT [TAKEDA PHARMACEUTICALS AMERICA, INC.]41Current NDC, Legacy NDC, 1 package rows20241224_d53a911f-070d-498a-8a61-baab72b9d0fe.zip

DailyMed RxNorm Mappings#

RxCUI, RxNorm string, TTY table
RxCUIRxNorm stringTTYDailyMedSPL version
1729336C1 esterase inhibitor (human) 500 UNT InjectionPSNd53a911f-070d-498a-8a61-baab72b9d0fe42
809871Cinryze 500 UNT InjectionPSNd53a911f-070d-498a-8a61-baab72b9d0fe42
809871C1 esterase inhibitor (human) 500 UNT Injection [Cinryze]SBDd53a911f-070d-498a-8a61-baab72b9d0fe42
1729336C1 esterase inhibitor (human) 500 UNT InjectionSCDd53a911f-070d-498a-8a61-baab72b9d0fe42
809871Cinryze 500 UNT InjectionSYd53a911f-070d-498a-8a61-baab72b9d0fe42

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionUnitsMarketing startMarketing endSampleExclude flagStatus
42227-081-01422270081015 mL in 1 VIAL, SINGLE-USE (42227-081-01) 5 ml2008-12-01NoNoCurrent
42227-081-05422270081051 VIAL, SINGLE-USE in 1 CARTON (42227-081-05) > 5 mL in 1 VIAL, SINGLE-USE (42227-081-01) 2008-12-010000-00-00NoNoCurrent