Sevoflurane

Product NDC
42677-308
11-digit product format
426770308
Labeler code
42677
Product ID
42677-308_47b367ce-bae5-a5cf-e063-6294a90acd21
Type
HUMAN PRESCRIPTION DRUG
Nonproprietary name
Sevoflurane
Dosage form
LIQUID
Route
RESPIRATORY (INHALATION)
Labeler
Shandong New Time Pharmaceutical Co., Ltd.
Application
ANDA214382
Marketing category
ANDA
Marketing start
2023-08-18
Substance
SEVOFLURANE
Active strength
250 mL/250mL
Pharmacologic classes
General Anesthesia [PE], General Anesthetic [EPC]
NDC exclude flag
No
Listing certified through
2027-12-31
Current FDA listing
Yes

Source provenance: Browse the complete Orange Book source catalog · source snapshot 42.

Orange Book products#

Current product rows page 1 of 1 · 1 matching rows.

Application-product, Trade name, Ingredient table
Application-productTrade nameIngredientStrengthDosage form / routeTE codesRLD / RSApproval date
A214382-001SEVOFLURANESEVOFLURANE100%LIQUID / INHALATIONAN2023-08-18

Therapeutic equivalence codes#

Current TE-code rows page 1 of 1 · 1 matching rows.

Application-product, TE code table
Application-productTE code
A214382-001AN

Observed Orange Book product history#

Observed FDA ZIP history: Each table is queried independently by exact application/product key from successfully parsed Orange Book snapshots. Capture times identify archived source observations; absence or a change between snapshots is not inferred. FDA publication files that were not recoverable as structured ZIP data are not represented as states.

Captured, Edition, Application-product table
CapturedEditionApplication-productTrade nameStrengthDosage form / routeProduct TE source textRLD / RSApproval dateSource SHA-256
2026-08-18 06:07:402026-07A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-18caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-18011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-1831067a03dcf5…
2025-08-23 18:47 UTC2025-08A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-186a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-18fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-18b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-1803ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-182680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-185bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-18d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-18d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-1879d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-18301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-181e350fbaab3a…
2024-05-31 18:47 UTC2024-05A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-188072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-186a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-181c564ffb4f44…
2023-12-20 04:57 UTC2023-12A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-18ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-18a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-189b2671bbb829…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A214382-001SEVOFLURANE100%LIQUID / INHALATIONAN2023-08-18a50c72e98297…

Observed Orange Book normalized TE history#

Captured, Edition, Application-product table
CapturedEditionApplication-productTE codeOrderSource SHA-256
2026-08-18 06:07:402026-07A214382-001AN1caaa826d4ba7…
2026-02-19 14:30 UTC2026-02A214382-001AN1011fe1cb6892…
2025-12-14 10:44 UTC · 2 captures of this ZIP2025-12A214382-001AN131067a03dcf5…
2025-08-23 18:47 UTC2025-08A214382-001AN16a471c1ec25d…
2025-03-22 03:13 UTC · 3 captures of this ZIP2025-03A214382-001AN1fd3edfee7708…
2025-02-26 10:13 UTC · 3 captures of this ZIP2025-02A214382-001AN1b8a1b40f171c…
2025-01-19 17:59 UTC · 7 captures of this ZIP2025-01A214382-001AN103ed91905a0d…
2024-12-13 21:23 UTC · 2 captures of this ZIP2024-12A214382-001AN12680178bc6a6…
2024-09-14 05:58 UTC · 2 captures of this ZIP2024-09A214382-001AN15bbf6a4d5a75…
2024-11-08 22:44 UTC · 3 captures of this ZIP2024-11A214382-001AN1d8e5a09893c0…
2024-10-29 15:01 UTC2024-10A214382-001AN1d06236e962d9…
2024-08-13 05:28 UTC · 3 captures of this ZIP2024-08A214382-001AN179d66fd596c7…
2024-07-13 05:37 UTC · 2 captures of this ZIP2024-07A214382-001AN1301d65b070ca…
2024-06-18 03:08 UTC · 5 captures of this ZIP2024-06A214382-001AN11e350fbaab3a…
2024-05-31 18:47 UTC2024-05A214382-001AN18072bd15b7f6…
2024-03-16 18:09 UTC · 4 captures of this ZIP2024-03A214382-001AN16a51e52b5d6a…
2024-02-18 07:12 UTC2024-02A214382-001AN11c564ffb4f44…
2023-12-20 04:57 UTC2023-12A214382-001AN1ea1830bbd6c7…
2023-11-28 05:40 UTC · 2 captures of this ZIP2023-11A214382-001AN1a72a2bbeb626…
2023-10-25 00:34 UTC · 2 captures of this ZIP2023-10A214382-001AN19b2671bbb829…
2026-07-26 02:55 UTC · 3 captures of this ZIP2026-06A214382-001AN1a50c72e98297…

Additional Listing Data#

Finished product
Yes
Brand name base
Sevoflurane
Listing expiration
2027-12-31

Active Ingredients#

Ingredient, Strength table
IngredientStrength
SEVOFLURANE250 mL/250mL

Harmonized UNII identifiers#

UNII identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
38LVP0K73AInternal UNII lookup

Harmonized RxCUI identifiers#

RxCUI identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
200243Internal RxNorm lookup

Harmonized SPL set identifiers#

SPL set identifiers page 1 of 1 · 1 matching rows.

Identifier, FDA.report destination table
IdentifierFDA.report destination
c808afe1-ebf1-44cf-9187-09656331bff5Available on FDA.report

DailyMed Product Concepts#

Product concept, Relation, Version table
Product conceptRelationVersionEffective
cf7269a1-35c0-eaae-99e6-6fe74a4680f4Product name320250516

DailyMed Package Descriptions#

Package NDC, Product, Description table
Package NDCProductDescriptionFormQuantityStrengthSPL version
42677-308-01Sevoflurane250 mL in 1 BOTTLE, GLASSLIQUID2505
42677-308-01Sevoflurane1 in 1 CARTONLIQUID15

DailyMed Dashboard NDC Coverage#

NDC, Dashboard title, SPL version table
NDCDashboard titleSPL versionValidationDashboard ZIP
42677-308SEVOFLURANE LIQUID [SHANDONG NEW TIME PHARMACEUTICAL CO., LTD.]4Current NDC, 2 package rows20241127_c808afe1-ebf1-44cf-9187-09656331bff5.zip

openFDA label cross-check#

OpenFDA label data provides additional search and identifier links. DailyMed’s Structured Product Label is the canonical label on FDA.report. Matching records are deduplicated before they are shown below.

Matched openFDA labels page 1 of 1 · 3 matching rows.

Brand, Generic, Manufacturer table
BrandGenericManufacturerSPL set IDEffective dateAvailable safety fieldsJoin
SevofluraneSEVOFLURANEShandong New Time Pharmaceutical Co., Ltd.c808afe1-ebf1-44cf-9187-09656331bff52026-06-02Warnings, Adverse reactionsExact identifier
application applno (ANDA): 214382
application number: ANDA214382
ndc (product): 42677-308
Sevoflurane, (Volatile for Inhalation)SEVOFLURANEMullan Pharmaceutical Inc.0ca6da3a-6a18-400d-8c49-08a5534b025f2026-03-23Warnings, Adverse reactionsExact identifier
application applno (ANDA): 214382
application number: ANDA214382
SevofluraneSEVOFLURANELannett Company, Inc.5bfc1cef-824d-4ebf-bb4d-fbc46c0abb792023-09-19Warnings, Adverse reactionsExact identifier
application applno (ANDA): 214382
application number: ANDA214382

Packages#

Package NDC, 11-digit format, Description table
Package NDC11-digit formatDescriptionMarketing startSampleExclude flagStatus
42677-308-01426770308011 BOTTLE, GLASS in 1 CARTON (42677-308-01) / 250 mL in 1 BOTTLE, GLASS2023-08-18NoNoCurrent